DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68035X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68031X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68037X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-262425X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-262427X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68034X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68032X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68033X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-68036X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. Structure (London, England : 1993) 2008 imex curation Robinson RA., Lu X., Jones EY., Siebold C. Only protein-protein interactions in vitro In vitro solid phase assay solid phase assay predetermined predetermined participant predetermined Robinson RA., Lu X., Jones EY., Siebold C. DIP original experiment: DIP-262426X Structure (London, England : 1993) 2008 IMEx Biochemical and structural studies of ASPP proteins reveal differential binding to p53, p63, and p73. p53_human Cellular tumor antigen p53 TP53 P53 Tumor suppressor p53 Phosphoprotein p53 Antigen NY-CO-13 protein protein human Homo sapiens Human MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD DIP protein P04637 original sequence version: 121 DIP protein P04637 original sequence version: 115 DIP protein P04637-1 original sequence version: 224 DIP protein P04637 original sequence version: 117 DIP protein P04637-1 original sequence version: 226 DIP protein P04637 original sequence version: 226 DIP protein P04637 original sequence version: 212 DIP protein P04637 original sequence version: 220 DIP protein P04637-1 original sequence version: 220 DIP protein P04637-1 original sequence version: 145 DIP protein P04637 original sequence version: 146 DIP protein P04637 original sequence version: 145 DIP protein P04637 original sequence version: 166 DIP protein P04637-1 original sequence version: 166 DIP protein P04637 original sequence version: 169 DIP protein P04637 original sequence version: 177 DIP protein P04637 original sequence version: 175 DIP protein P04637-1 original sequence version: 175 DIP protein P04637-1 original sequence version: 172 DIP protein P04637-1 original sequence version: 169 DIP protein P04637 original sequence version: 170 DIP protein P04637 original sequence version: 172 DIP protein P04637-1 original sequence version: 194 DIP protein P04637 original sequence version: 196 DIP protein P04637 original sequence version: 185 DIP protein P04637-1 original sequence version: 191 DIP protein P04637 original sequence version: 191 DIP protein P04637 original sequence version: 180 DIP protein P04637-1 original sequence version: 197 DIP protein P04637 original sequence version: 183 DIP protein P04637-1 original sequence version: 183 DIP protein P04637-1 original sequence version: 185 DIP protein P04637 original sequence version: 199 DIP protein P04637 original sequence version: 201 DIP protein P04637 original sequence version: 189 DIP protein P04637 original sequence version: 235 DIP protein P04637 original sequence version: 230 DIP protein P04637 original sequence version: 234 DIP protein P04637-1 original sequence version: 234 DIP protein P04637-1 original sequence version: 235 DIP protein P04637 original sequence version: 239 DIP protein P04637-1 original sequence version: 212 DIP protein P04637-1 original sequence version: 213 DIP protein P04637 original sequence version: 213 DIP protein P04637 original sequence version: 206 DIP protein P04637-1 original sequence version: 188 DIP protein P04637-1 original sequence version: 228 DIP protein P04637 original sequence version: 208 DIP protein P04637 original sequence version: 240 DIP protein P04637-1 original sequence version: 240 DIP protein P04637 original sequence version: 204 DIP protein P04637-1 original sequence version: 204 DIP protein P04637-1 original sequence version: 209 DIP protein P04637-1 original sequence version: 203 DIP protein P04637 original sequence version: 221 DIP protein P04637-1 original sequence version: 152 DIP protein P04637 original sequence version: 217 DIP protein P04637-1 original sequence version: 140 DIP protein P04637 original sequence version: 215 DIP protein P04637 original sequence version: 214 DIP protein P04637-1 original sequence version: 182 DIP protein P04637 original sequence version: 182 DIP protein P04637 original sequence version: 188 DIP protein P04637 original sequence version: 192 DIP protein P04637-1 original sequence version: 192 DIP protein P04637 original sequence version: 218 DIP protein P04637-1 original sequence version: 218 AD5C149FD8106131 p63_human Tumor protein 63 TP63 KET P63 P73H P73L TP73L Transformation-related protein 63 Tumor protein p73-like p51 p40 Keratinocyte transcription factor KET Chronic ulcerative stomatitis protein protein protein human Homo sapiens Human MNFETSRCATLQYCPDPYIQRFVETPAHFSWKESYYRSTMSQSTQTNEFLSPEVFQHIWDFLEQPICSVQPIDLNFVDEPSEDGATNKIEISMDCIRMQDSDLSDPMWPQYTNLGLLNSMDQQIQNGSSSTSPYNTDHAQNSVTAPSPYAQPSSTFDALSPSPAIPSNTDYPGPHSFDVSFQQSSTAKSATWTYSTELKKLYCQIAKTCPIQIKVMTPPPQGAVIRAMPVYKKAEHVTEVVKRCPNHELSREFNEGQIAPPSHLIRVEGNSHAQYVEDPITGRQSVLVPYEPPQVGTEFTTVLYNFMCNSSCVGGMNRRPILIIVTLETRDGQVLGRRCFEARICACPGRDRKADEDSIRKQQVSDSTKNGDGTKRPFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQHLLQKQTSIQSPSSYGNSSPPLNKMNSMNKLPSVSQLINPQQRNALTPTTIPDGMGANIPMMGTHMPMAGDMNGLSPTQALPPPLSMPSTSHCTPPPPYPTDCSIVSFLARLGCSSCLDYFTTQGLTTIYQIEHYSMDDLASLKIPEQFRHAIWKGILDHRQLHEFSSPSHLLRTPSSASTVSVGSSETRGERVIDAVRFTLRQTISFPPRDEWNDFNFDMDARRNKQQRIKEEGE DIP protein Q9H3D4 original sequence version: 99 DIP protein Q9H3D4 original sequence version: 100 DIP protein Q9H3D4 original sequence version: 119 DIP protein Q9H3D4-1 original sequence version: 146 DIP protein Q9H3D4 original sequence version: 146 DIP protein Q9H3D4 original sequence version: 142 DIP protein Q9H3D4 original sequence version: 68 F66ECD45E87D9799 iaspp_human RelA-associated inhibitor PPP1R13L IASPP NKIP1 PPP1R13BL RAI Inhibitor of ASPP protein NFkB-interacting protein 1 PPP1R13B-like protein protein protein human Homo sapiens Human MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQAGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSSPRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGRAGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDLTLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTGKDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPEQPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEGITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIFATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFREGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV DIP protein Q8WUF5 original sequence version: 129 DIP protein Q8WUF5 original sequence version: 52 7BEEF239B7CA9C70 p73_human Tumor protein p73 TP73 P73 p53-like transcription factor p53-related protein protein protein human Homo sapiens Human MAQSTATSPDGGTTFEHLWSSLEPDSTYFDLPQSSRGNNEVVGGTDSSMDVFHLEGMTTSVMAQFNLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVIPSNTDYPGPHHFEVTFQQSSTAKSATWTYSPLLKKLYCQIAKTCPIQIKVSTPPPPGTAIRAMPVYKKAEHVTDVVKRCPNHELGRDFNEGQSAPASHLIRVEGNNLSQYVDDPVTGRQSVVVPYEPPQVGTEFTTILYNFMCNSSCVGGMNRRPILIIITLEMRDGQVLGRRSFEGRICACPGRDRKADEDHYREQQALNESSAKNGAASKRAFKQSPPAVPALGAGVKKRRHGDEDTYYLQVRGRENFEILMKLKESLELMELVPQPLVDSYRQQQQLLQRPSHLQPPSYGPVLSPMNKVHGGMNKLPSVNQLVGQPPPHSSAATPNLGPVGPGMLNNHGHAVPANGEMSSSHSAQSMVSGSHCTPPPPYHADPSLVSFLTGLGCPNCIEYFTSQGLQSIYHLQNLTIEDLGALKIPEQYRMTIWRGLQDLKQGHDYSTAQQLLRSSNAATISIGGSGELQRQRVMEAVHFRVRHTITIPNRGGPGGGPDEWADFGFDLPDCKARKQPIKEEFTEAEIH DIP protein O15350 original sequence version: 170 DIP protein O15350-1 original sequence version: 100 DIP protein O15350 original sequence version: 123 DIP protein O15350 original sequence version: 149 DIP protein O15350-1 original sequence version: 165 DIP protein O15350 original sequence version: 92 DIP protein O15350-1 original sequence version: 122 DIP protein O15350-1 original sequence version: 135 DIP protein O15350-1 original sequence version: 174 A467493C5D93EEE0 aspp2_human Apoptosis-stimulating of p53 protein 2 TP53BP2 ASPP2 BBP Tumor suppressor p53-binding protein 2 Bcl2-binding protein Renal carcinoma antigen NY-REN-51 protein protein human Homo sapiens Human MMPMFLTVYLSNNEQHFTEVPVTPETICRDVVDLCKEPGESDCHLAEVWCGSERPVADNERMFDVLQRFGSQRNEVRFFLRHERPPGRDIVSGPRSQDPSLKRNGVKVPGEYRRKENGVNSPRMDLTLAELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQEAKLKKVRALKGHVEQKRLSNGKLVEEIEQMNNLFQQKQRELVLAVSKVEELTRQLEMLKNGRIDSHHDNQSAVAELDRLYKELQLRNKLNQEQNAKLQQQRECLNKRNSEVAVMDKRVNELRDRLWKKKAALQQKENLPVSSDGNLPQQAASAPSRVAAVGPYIQSSTMPRMPSRPELLVKPALPDGSLVIQASEGPMKIQTLPNMRSGAASQTKGSKIHPVGPDWSPSNADLFPSQGSASVPQSTGNALDQVDDGEVPLREKEKKVRPFSMFDAVDQSNAPPSFGTLRKNQSSEDILRDAQVANKNVAKVPPPVPTKPKQINLPYFGQTNQPPSDIKPDGSSQQLSTVVPSMGTKPKPAGQQPRVLLSPSIPSVGQDQTLSPGSKQESPPAAAVRPFTPQPSKDTLLPPFRKPQTVAASSIYSMYTQQQAPGKNFQQAVQSALTKTHTRGPHFSSVYGKPVIAAAQNQQQHPENIYSNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNASTENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDVYLEEYPPYPPPPYPSGEPEGPGEDSVSMRPPEITGQVSLPPGKRTNLRKTGSERIAHGMRVKFNPLALLLDSSLEGEFDLVQRIIYEVDDPSLPNDEGITALHNAVCAGHTEIVKFLVQFGVNVNAADSDGWTPLHCAASCNNVQVCKFLVESGAAVFAMTYSDMQTAADKCEEMEEGYTQCSQFLYGVQEKMGIMNKGVIYALWDYEPQNDDELPMKEGDCMTIIHREDEDEIEWWWARLNDKEGYVPRNLLGLYPRIKPRQRSLA DIP protein Q13625 original sequence version: 114 DIP protein Q13625 original sequence version: 156 DIP protein Q13625-1 original sequence version: 156 DIP protein Q13625 original sequence version: 160 DIP protein Q13625-1 original sequence version: 86 C75D056FBC1DAD75 tp63-ppp1r13l-1 8 12 unspecified role unspecified role bait bait Region 123-323 Region 123-323 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 13 unspecified role unspecified role prey prey Region 625-828 Region 625-828 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tp63-tp53bp2-1 9 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 12 unspecified role unspecified role bait bait Region 123-323 Region 123-323 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tp53-ppp1r13l-5 7 11 unspecified role unspecified role bait bait Region 94-292 Region 94-292 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 13 unspecified role unspecified role prey prey Region 625-828 Region 625-828 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tp53-tp53bp2-2 1 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 11 unspecified role unspecified role bait bait Region 94-292 Region 94-292 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction ppp1r13l-ppp1r13l-2 2 13 unspecified role unspecified role unspecified role unspecified role Region 625-828 Region 625-828 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 13 unspecified role unspecified role unspecified role unspecified role Region 616-623 Region 616-623 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction tp73-ppp1r13l-1 6 14 unspecified role unspecified role bait bait Region 112-312 Region 112-312 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 13 unspecified role unspecified role prey prey Region 625-828 Region 625-828 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tp73-tp53bp2-1 3 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 14 unspecified role unspecified role bait bait Region 112-312 Region 112-312 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction tp63-tp53bp2-2 4 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 12 unspecified role unspecified role bait bait Region 123-323 Region 123-323 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction 1 nodeMerge04 2014-11-30 tp53-tp53bp2-3 10 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 11 unspecified role unspecified role bait bait Region 94-292 Region 94-292 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction 1 nodeMerge04 2014-11-30 tp73-tp53bp2-2 5 15 unspecified role unspecified role prey prey Region 905-1128 Region 905-1128 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 14 unspecified role unspecified role bait bait Region 112-312 Region 112-312 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction 1 nodeMerge04 2014-11-30