DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Buxbaum JN., Ye Z., Reixach N., Friske L., Levy C., Das P., Golde T., Masliah E., Roberts AR., Bartfai T. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Buxbaum JN., Ye Z., Reixach N., Friske L., Levy C., Das P., Golde T., Masliah E., Roberts AR., Bartfai T. DIP original experiment: DIP-68302X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proceedings of the National Academy of Sciences of the United States of America 2008 imex curation Buxbaum JN., Ye Z., Reixach N., Friske L., Levy C., Das P., Golde T., Masliah E., Roberts AR., Bartfai T. Only protein-protein interactions in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Buxbaum JN., Ye Z., Reixach N., Friske L., Levy C., Das P., Golde T., Masliah E., Roberts AR., Bartfai T. DIP original experiment: DIP-68303X Proceedings of the National Academy of Sciences of the United States of America 2008 IMEx Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. tthy_mouse Transthyretin Ttr Prealbumin protein protein mouse Mus musculus Mouse MASLRLFLLCLAGLVFVSEAGPAGAGESKCPLMVKVLDAVRGSPAVDVAVKVFKKTSEGSWEPFASGKTAESGELHGLTTDEKFVEGVYRVELDTKSYWKTLGISPFHEFADVVFTANDSGHRHYTIAALLSPYSYSTTAVVSNPQN DIP protein P07309 original sequence version: 73 mint Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain 9803CCC3024BA911 p05067-pro_0000000092 Amyloid-beta protein 42 Alzheimer disease amyloid protein Cerebral vascular amyloid peptide APP A4 AD1 ABPP PreA4 Protease nexin-II APPI Amyloid precursor protein Amyloid-beta A4 protein Alzheimer disease amyloid A4 protein homolog Amyloid-beta (A4) precursor protein protein protein human Homo sapiens Human DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 672 713 3AC85563D7858C37 tthy_human Transthyretin Prealbumin TBPA ATTR TTR PALB protein protein human Homo sapiens Human MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE DIP protein P02766 original sequence version: 114 DIP protein P02766 original sequence version: 163 DIP protein P02766 original sequence version: 174 3A6AEBCBBA56BC44 p12023-pro_0000000118 Amyloid-beta protein 42 App ABPP Alzheimer disease amyloid A4 protein homolog Amyloid precursor protein Amyloidogenic glycoprotein A4 AD1 Alzheimer disease amyloid protein Amyloid-beta (A4) precursor protein Amyloid-beta A4 protein protein protein mouse Mus musculus Mouse DAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA 672 713 68706EF3D7839B56 ttr-app-1 1 4 unspecified role unspecified role prey prey Region 1-40 Region 1-40 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 5 unspecified role unspecified role bait bait ecolx Escherichia coli direct interaction direct interaction ttr-amyloidbeta-2 2 3 unspecified role unspecified role bait bait ecolx Escherichia coli 6 unspecified role unspecified role prey prey in vitro In vitro direct interaction direct interaction