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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18033300" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature06306" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15671928" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-21334" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Collison LW.,  Workman CJ.,  Kuo TT.,  Boyd K.,  Wang Y.,  Vignali KM.,  Cross R.,  Sehy D.,  Blumberg RS.,  Vignali DA.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21334" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-253780X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="18033300" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature06306" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="10090">
            <names>
              <shortLabel>mouse</shortLabel>
              <fullName>Mus musculus</fullName>
              <alias type="synonym" typeAc="MI:1041">Mouse</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Collison LW., Workman CJ., Kuo TT., Boyd K., Wang Y., Vignali KM., Cross R., Sehy D., Blumberg RS., Vignali DA.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253780X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="18033300" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature06306" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15671928" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-21334" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Collison LW.,  Workman CJ.,  Kuo TT.,  Boyd K.,  Wang Y.,  Vignali KM.,  Cross R.,  Sehy D.,  Blumberg RS.,  Vignali DA.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21334" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-253781X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="18033300" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nature06306" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human</shortLabel>
              <fullName>Homo sapiens</fullName>
              <alias type="synonym" typeAc="MI:1041">Human</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Collison LW., Workman CJ., Kuo TT., Boyd K., Wang Y., Vignali KM., Cross R., Sehy D., Blumberg RS., Vignali DA.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253781X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">The inhibitory cytokine IL-35 contributes to regulatory T-cell function.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>il27b_human</shortLabel>
          <fullName>Interleukin-27 subunit beta</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Epstein-Barr virus-induced gene 3 protein</alias>
          <alias type="gene name" typeAc="MI:0301">EBI3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IL27B</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q14213" version="SP_58" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000221847" version="SP_175" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O75269" version="SP_58" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A0N0N2" version="SP_80" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-742959" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000105246" version="SP_175" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000221847" version="SP_175" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004896" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005788" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005886" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006959" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017046" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019955" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033210" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042088" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" version="SP_175"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046641" version="SP_175"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003530" version="SP_175"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003961" version="SP_175"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_175"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036116" version="SP_175"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8984722" version="SP_175"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9020956" version="SP_175"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005746.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011525921.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-57556N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MTPQLLLALVLWASCPPCSGRKGPPAALTLPRVQCRASRYPIAVDCSWTLPPAPNSTSPVSFIATYRLGMAARGHSWPCLQQTPTSTSCTITDVQLFSMAPYVLNVTAVHPWGSSSSFVPFITEHIIKPDPPEGVRLSPLAERQLQVQWEPPGSWPFPEIFSLKYWIRYKRQGAARFHRVGPIEATSFILRAVRPRARYYVQVAAQDLTDYGELSDWSLPATATMSLGK</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q14213 original sequence version: 108</attribute>
          <attribute name="remark-internal">DIP protein Q14213 original sequence version: 93</attribute>
          <attribute name="crc64">CFBAD72D91859EF0</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>il12a_mouse</shortLabel>
          <fullName>Interleukin-12 subunit alpha</fullName>
          <alias type="gene name" typeAc="MI:0301">Il12a</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cytotoxic lymphocyte maturation factor 35 kDa subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IL-12 subunit p35</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P43431" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000103446" version="SP_154" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3862959" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_032377.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001152896.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60363N"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000027776" version="SP_154" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000107816" version="SP_154" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001916" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002860" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005143" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005788" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005796" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008083" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008283" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009986" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010224" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031904" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032700" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032816" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032946" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034393" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035711" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042102" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042163" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042531" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042832" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043514" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045513" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045582" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045785" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045954" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048662" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050671" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050709" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051135" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071222" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900747" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903588" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000510" version="SP_154"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004281" version="SP_154"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009079" version="SP_154"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" version="SP_154"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MCQSRYLLFLATLALLNHLSLARVIPVSGPARCLSQSRNLLKTTDDMVKTAREKLKHYSCTAEDIDHEDITRDQTSTLKTCLPLELHKNESCLATRETSSTTRGSCLPPQKTSLMMTLCLGSIYEDLKMYQTEFQAINAALQNHNHQQIILDKGMLVAIDELMQSLNHNGETLRQKPPVGEADPYRVKMKLCILLHAFSTRVVTINRVMGYLSSA</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P43431 original sequence version: 99</attribute>
          <attribute name="crc64">56845B9B66D35A53</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>il12a_human</shortLabel>
          <fullName>Interleukin-12 subunit alpha</fullName>
          <alias type="gene name" typeAc="MI:0301">IL12A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NKSF1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">IL-12 subunit p35</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Cytotoxic lymphocyte maturation factor 35 kDa subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">NK cell stimulatory factor chain 1</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P29459" version="SP_71" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q96QZ1" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000303231" version="SP_186" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1029636" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000873.2"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032729" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032816" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032946" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034393" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042163" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042531" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043514" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045513" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045785" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032700" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045954" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046982" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048662" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050671" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050709" version="SP_186"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000168811" version="SP_186" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000305579" version="SP_186" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001916" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002860" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005143" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005576" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005788" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006955" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008083" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009615" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0010224" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016477" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031906" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032496" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051135" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051726" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097191" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098586" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1900747" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1903588" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000510" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR004281" version="SP_186"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009079" version="SP_186"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1F45" version="SP_186"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3HMX" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6783783" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6785807" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8984722" version="SP_186"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9020591" version="SP_186"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050830" version="SP_186"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-3772N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MCPARSLLLVATLVLLDHLSLARNLPVATPDPGMFPCLHHSQNLLRAVSNMLQKARQTLEFYPCTSEEIDHEDITKDKTSTVEACLPLELTKNESCLNSRETSFITNGSCLASRKTSFMMALCLSSIYEDLKMYQVEFKTMNAKLLMDPKRQIFLDQNMLAVIDELMQALNFNSETVPQKSSLEEPDFYKTKIKLCILLHAFRIRAVTIDRVMSYLNAS</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P29459 original sequence version: 129</attribute>
          <attribute name="crc64">7C658AB7716112B2</attribute>
        </attributeList>
      </interactor>
      <interactor id="6">
        <names>
          <shortLabel>il27b_mouse</shortLabel>
          <fullName>Interleukin-27 subunit beta</fullName>
          <alias type="gene name" typeAc="MI:0301">Ebi3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Epstein-Barr virus-induced gene 3 protein homolog</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Il27b</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O35228" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSP00000003274" version="SP_156" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-3862967" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_056581.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60364N"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUSG00000003206" version="SP_156" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSMUST00000003274" version="SP_156" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004896" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005125" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005615" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009897" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017046" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019221" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019955" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033210" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042098" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043235" version="SP_156"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045523" version="SP_156"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003530" version="SP_156"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR003961" version="SP_156"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013783" version="SP_156"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015373" version="SP_156"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036116" version="SP_156"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-8984722" version="SP_156"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-MMU-9020956" version="SP_156"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MSKLLFLSLALWASRSPGYTETALVALSQPRVQCHASRYPVAVDCSWTPLQAPNSTRSTSFIATYRLGVATQQQSQPCLQRSPQASRCTIPDVHLFSTVPYMLNVTAVHPGGASSSLLAFVAERIIKPDPPEGVRLRTAGQRLQVLWHPPASWPFPDIFSLKYRLRYRRRGASHFRQVGPIEATTFTLRNSKPHAKYCIQVSAQDLTDYGKPSDWSLPGQVESAPHKP</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O35228 original sequence version: 99</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="7" imexId="IM-21334-1">
        <names>
          <shortLabel>il12a-ebi3-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191505E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15671947" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-21334-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <interactorRef>6</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="10090">
                <names>
                  <shortLabel>mouse</shortLabel>
                  <fullName>Mus musculus</fullName>
                  <alias type="synonym" typeAc="MI:1041">Mouse</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="9">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="10090">
                <names>
                  <shortLabel>mouse</shortLabel>
                  <fullName>Mus musculus</fullName>
                  <alias type="synonym" typeAc="MI:1041">Mouse</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="10" imexId="IM-21334-2">
        <names>
          <shortLabel>il12a-ebi3-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191506E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15671964" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-21334-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="11">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9606">
                <names>
                  <shortLabel>human</shortLabel>
                  <fullName>Homo sapiens</fullName>
                  <alias type="synonym" typeAc="MI:1041">Human</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="12">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9606">
                <names>
                  <shortLabel>human</shortLabel>
                  <fullName>Homo sapiens</fullName>
                  <alias type="synonym" typeAc="MI:1041">Human</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>