DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Wollert T., Heinz DW., Schubert WD. Only protein-protein interactions in vitro In vitro itc isothermal titration calorimetry ITC ITC itc predetermined predetermined participant predetermined Wollert T., Heinz DW., Schubert WD. DIP original experiment: DIP-113923X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Wollert T., Heinz DW., Schubert WD. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Wollert T., Heinz DW., Schubert WD. DIP original experiment: DIP-113924X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. cadh1_human Cadherin-1 Epithelial cadherin Uvomorulin CAM 120/80 CDH1 CDHE UVO protein protein human Homo sapiens Human MGPWSRSLSALLLLLQVSSWLCQEPEPCHPGFDAESYTFTVPRRHLERGRVLGRVNFEDCTGRQRTAYFSLDTRFKVGTDGVITVKRPLRFHNPQIHFLVYAWDSTYRKFSTKVTLNTVGHHHRPPPHQASVSGIQAELLTFPNSSPGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPRYLPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADMYGGGEDD DIP protein P12830 original sequence version: 191 DIP protein P12830 original sequence version: 185 DIP protein P12830 original sequence version: 108 DIP protein P12830 original sequence version: null DIP protein P12830 original sequence version: 134 DIP protein P12830 original sequence version: 147 DIP protein P12830 original sequence version: 174 DIP protein P12830 original sequence version: 189 DIP protein P12830 original sequence version: 156 DIP protein P12830 original sequence version: 201 DIP protein P12830 original sequence version: 117 E427118043A13C67 inla_lismo Internalin A inlA lmo0433 protein protein lismo Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) MRKKRYVWLKSILVAILVFGSGVWINTSNGTNAQAATITQDTPINQIFTDTALAEKMKTVLGKTNVTDTVSQTDLDQVTTLQADRLGIKSIDGVEYLNNLTQINFSNNQLTDITPLKNLTKLVDILMNNNQIADITPLANLTNLTGLTLFNNQITDIDPLKNLTNLNRLELSSNTISDISALSGLTSLQQLSFGNQVTDLKPLANLTTLERLDISSNKVSDISVLAKLTNLESLIATNNQISDITPLGILTNLDELSLNGNQLKDIGTLASLTNLTDLDLANNQISNLAPLSGLTKLTELKLGANQISNISPLAGLTALTNLELNENQLEDISPISNLKNLTYLTLYFNNISDISPVSSLTKLQRLFFYNNKVSDVSSLANLTNINWLSAGHNQISDLTPLANLTRITQLGLNDQAWTNAPVNYKANVSIPNTVKNVTGALIAPATISDGGSYTEPDITWNLPSYTNEVSYTFSQPVTIGKGTTTFSGTVTQPLKAIFNVKFHVDGKETTKEVEAGNLLTEPAKPVKEGHTFVGWFDAQTGGTKWNFSTDKMPTNDINLYAQFSINSYTATFDNDGVTTSQTVDYQGLLQEPTAPTKEGYTFKGWYDAKTGGDKWDFATSKMPAKNITLYAQYSANSYTATFDVDGKSTTQAVDYQGLLKEPKAPTKAGYTFKGWYDEKTDGKKWDFATDKMPANDITLYAQFTKNPVAPPTTGGNTPPTTNNGGNTTPPSANIPGSDTSNTSTGNSASTTSTMNAYDPYNSKEASLPTTGDSDNALYLLLGLLAVGTAMALTKKARASK 4D1B03A5CF7CCDE3 4D1B03A5CF7CCDE3 cdh1-inla-2 1 3 unspecified role unspecified role unspecified role unspecified role N-terminal domain 1-105 N-terminal domain 1-105 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role P0DJM0:p.Tyr369Ser mutation increasing strength mutation increasing interaction strength mutation increasing strength certain certain sequence position certain certain certain sequence position certain Y S Wed May 02 19:13:33 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr369ser' Tue Jun 30 18:14:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr369Ser' P0DJM0:p.Tyr369Ala Y369A/S mutation increasing strength mutation increasing interaction strength mutation increasing strength mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Y A Wed May 02 14:46:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr369ala' Tue Jun 30 19:00:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr369Ala' P0DJM0:p.Ser192Asn S192N mutation increasing mutation increasing interaction mutation increasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S N This feature has been corrected as a result of our quality control procedures. The original label was 'S192N'. Wed May 02 16:27:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser192asn' Tue Jun 30 17:56:59 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser192Asn' Region 36-496 Region 36-496 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction cdh1-inla-3 2 3 unspecified role unspecified role unspecified role unspecified role N-terminal domain 1-105 N-terminal domain 1-105 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role P0DJM0:p.Tyr369Ser mutation increasing strength mutation increasing interaction strength mutation increasing strength certain certain sequence position certain certain certain sequence position certain Y S Wed May 02 18:53:57 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr369ser' Tue Jun 30 16:01:56 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr369Ser' P0DJM0:p.Tyr369Ala Y369A/S mutation increasing strength mutation increasing interaction strength mutation increasing strength mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Y A Wed May 02 15:22:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr369ala' Tue Jun 30 15:41:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr369Ala' P0DJM0:p.Ser192Asn S192N mutation increasing mutation increasing interaction mutation increasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain S N This feature has been corrected as a result of our quality control procedures. The original label was 'S192N'. Wed May 02 17:25:20 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser192asn' Tue Jun 30 19:33:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser192Asn' Region 36-496 Region 36-496 binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction