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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
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        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>TRIC channels are essential for Ca2+ handling in intracellular stores.</fullName>
        </names>
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          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="17611541" refType="primary-reference" refTypeAc="MI:0358"/>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Yazawa M.,  Ferrante C.,  Feng J.,  Mio K.,  Ogura T.,  Zhang M.,  Lin PH.,  Pan Z.,  Komazaki S.,  Kato K.,  Nishi M.,  Zhao X.,  Weisleder N.,  Sato C.,  Ma J.,  Takeshima H.</attribute>
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        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21182" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="562">
            <names>
              <shortLabel>ecolx</shortLabel>
              <fullName>Escherichia coli</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>crosslink</shortLabel>
            <fullName>cross-linking study</fullName>
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          <xref>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>anti tag western</shortLabel>
            <fullName>anti tag western blot</fullName>
            <alias type="synonym" typeAc="MI:1041">anti tag western</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0705" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-967832" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Yazawa M., Ferrante C., Feng J., Mio K., Ogura T., Zhang M., Lin PH., Pan Z., Komazaki S., Kato K., Nishi M., Zhao X., Weisleder N., Sato C., Ma J., Takeshima H.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253194X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
        </attributeList>
      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>TRIC channels are essential for Ca2+ handling in intracellular stores.</fullName>
        </names>
        <bibref>
          <xref>
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            <secondaryRef db="imex" dbAc="MI:0670" id="IM-21182" refType="imex-primary" refTypeAc="MI:0662"/>
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            <attribute name="publication title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nature</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Yazawa M.,  Ferrante C.,  Feng J.,  Mio K.,  Ogura T.,  Zhang M.,  Lin PH.,  Pan Z.,  Komazaki S.,  Kato K.,  Nishi M.,  Zhao X.,  Weisleder N.,  Sato C.,  Ma J.,  Takeshima H.</attribute>
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            <attribute name="imex curation" nameAc="MI:0959"/>
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        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21182" refType="imex-primary" refTypeAc="MI:0662"/>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9986">
            <names>
              <shortLabel>rabit</shortLabel>
              <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
              <alias type="synonym" typeAc="MI:1041">Rabbit</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>tem</shortLabel>
            <fullName>transmission electron microscopy</fullName>
            <alias type="synonym" typeAc="MI:1041">tem</alias>
          </names>
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            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0020" refType="identity" refTypeAc="MI:0356"/>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
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          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Yazawa M., Ferrante C., Feng J., Mio K., Ogura T., Zhang M., Lin PH., Pan Z., Komazaki S., Kato K., Nishi M., Zhao X., Weisleder N., Sato C., Ma J., Takeshima H.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253192X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
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      <experimentDescription id="3">
        <names>
          <fullName>TRIC channels are essential for Ca2+ handling in intracellular stores.</fullName>
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            <attribute name="publication title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
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            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
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            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-21182" refType="imex-primary" refTypeAc="MI:0662"/>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="9986">
            <names>
              <shortLabel>rabit</shortLabel>
              <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
              <alias type="synonym" typeAc="MI:1041">Rabbit</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>crosslink</shortLabel>
            <fullName>cross-linking study</fullName>
            <alias type="synonym" typeAc="MI:1041">crosslink</alias>
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          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0030" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
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            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
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          <attribute name="author-list" nameAc="MI:0636">Yazawa M., Ferrante C., Feng J., Mio K., Ogura T., Zhang M., Lin PH., Pan Z., Komazaki S., Kato K., Nishi M., Zhao X., Weisleder N., Sato C., Ma J., Takeshima H.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-253193X</attribute>
          <attribute name="journal" nameAc="MI:0885">Nature</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">TRIC channels are essential for Ca2+ handling in intracellular stores.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="4">
        <names>
          <shortLabel>tm38a_rabit</shortLabel>
          <fullName>Trimeric intracellular cation channel type A</fullName>
          <alias type="gene name" typeAc="MI:0301">TMEM38A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MG33A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Mitsugumin-33A</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Transmembrane protein 38A</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="A5A6S6" version="32" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15646422" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005267" version="SP_57"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="SP_57"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031965" version="SP_57"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033017" version="SP_57"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_57"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007866" version="SP_57"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001093439.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-60261N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9986">
          <names>
            <shortLabel>rabit</shortLabel>
            <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
            <alias type="synonym" typeAc="MI:1041">Rabbit</alias>
          </names>
        </organism>
        <sequence>MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPLIDYFSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKGSGVALLSNVEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTMFMVSCKVFLTATHSHSSPFDVLEAYVCPVLFGTGSGGDHPQDNHGAWPGGPPSGALATKSKEELSEGSRKKKTKKAD</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein A5A6S6 original sequence version: 32</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-21182-1">
        <names>
          <shortLabel>tmem38a-1</shortLabel>
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          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191064E" refType="identity" refTypeAc="MI:0356"/>
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        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
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                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9986">
                <names>
                  <shortLabel>rabit</shortLabel>
                  <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Rabbit</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
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            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionType>
      </interaction>
      <interaction id="7" imexId="IM-21182-2">
        <names>
          <shortLabel>tmem38a-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191064E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15646454" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-21182-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>3</experimentRef>
        </experimentList>
        <participantList>
          <participant id="8">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="9986">
                <names>
                  <shortLabel>rabit</shortLabel>
                  <fullName>Oryctolagus cuniculus (Rabbit)</fullName>
                  <alias type="synonym" typeAc="MI:1041">Rabbit</alias>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
      <interaction id="9" imexId="IM-21182-3">
        <names>
          <shortLabel>tmem38a-3</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-191064E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15646470" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-21182-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="11">
                <names>
                  <shortLabel>HA-tag</shortLabel>
                  <fullName>HA-tag</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-15646475" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>ha tag</shortLabel>
                    <fullName>ha tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">YPYDVPDYA epitope tag</alias>
                    <alias type="synonym" typeAc="MI:1041">YPYDVPDYA epitope tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0520" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456513" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>c-term range</shortLabel>
                        <fullName>C-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">c-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1039" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929799" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>