DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. Only protein-protein interactions ecolx Escherichia coli molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column predetermined predetermined participant predetermined Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. DIP original experiment: DIP-261659X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. Only protein-protein interactions ecolx Escherichia coli light scattering light scattering predetermined predetermined participant predetermined Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. DIP original experiment: DIP-261662X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. Only protein-protein interactions ecolx Escherichia coli ms of complexes mass spectrometry studies of complexes ms of complexes predetermined predetermined participant predetermined Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. DIP original experiment: DIP-261660X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. Only protein-protein interactions ecolx Escherichia coli fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Banci L., Bertini I., Durazo A., Girotto S., Gralla EB., Martinelli M., Valentine JS., Vieru M., Whitelegge JP. DIP original experiment: DIP-261661X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: a possible general mechanism for familial ALS. sodc_human Superoxide dismutase [Cu-Zn] Superoxide dismutase 1 SOD1 protein protein human Homo sapiens Human MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ DIP protein P00441 original sequence version: 194 DIP protein P00441 original sequence version: 189 DIP protein P00441 original sequence version: 186 DIP protein P00441 original sequence version: 147 DIP protein P00441 original sequence version: 148 DIP protein P00441 original sequence version: 145 DIP protein P00441 original sequence version: 169 25CA38DA8D564483 sod1-1 1 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction sod1-2 3 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction sod1-3 4 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction sod1-4 2 5 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction