DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Guo RT., Cao R., Liang PH., Ko TP., Chang TH., Hudock MP., Jeng WY., Chen CK., Zhang Y., Song Y., Kuo CJ., Yin F., Oldfield E., Wang AH. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Guo RT., Cao R., Liang PH., Ko TP., Chang TH., Hudock MP., Jeng WY., Chen CK., Zhang Y., Song Y., Kuo CJ., Yin F., Oldfield E., Wang AH. DIP original experiment: DIP-261579X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Guo RT., Cao R., Liang PH., Ko TP., Chang TH., Hudock MP., Jeng WY., Chen CK., Zhang Y., Song Y., Kuo CJ., Yin F., Oldfield E., Wang AH. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Guo RT., Cao R., Liang PH., Ko TP., Chang TH., Hudock MP., Jeng WY., Chen CK., Zhang Y., Song Y., Kuo CJ., Yin F., Oldfield E., Wang AH. DIP original experiment: DIP-261578X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. upps_ecoli Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) ispU Ditrans,polycis-undecaprenylcistransferase Undecaprenyl diphosphate synthase Undecaprenyl pyrophosphate synthase rth uppS yaeS JW0169 b0174 protein protein ecoli Escherichia coli (strain K12) MMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA DIP protein P60472 original sequence version: 102 73DC9534C14CA7B9 ggpps_yeast Geranylgeranyl pyrophosphate synthase YPL069C BTS1 Geranylgeranyl diphosphate synthase BET2 suppressor protein 1 (2E,6E)-farnesyl diphosphate synthase Dimethylallyltranstransferase Farnesyl diphosphate synthase Farnesyltranstransferase Geranyltranstransferase protein protein yeast Saccharomyces cerevisiae Baker's yeast MEAKIDELINNDPVWSSQNESLISKPYNHILLKPGKNFRLNLIVQINRVMNLPKDQLAIVSQIVELLHNSSLLIDDIEDNAPLRRGQTTSHLIFGVPSTINTANYMYFRAMQLVSQLTTKEPLYHNLITIFNEELINLHRGQGLDIYWRDFLPEIIPTQEMYLNMVMNKTGGLFRLTLRLMEALSPSSHHGHSLVPFINLLGIIYQIRDDYLNLKDFQMSSEKGFAEDITEGKLSFPIVHALNFTKTKGQTEQHNEILRILLLRTSDKDIKLKLIQILEFDTNSLAYTKNFINQLVNMIKNDNENKYLPDLASHSDTATNLHDELLYIIDHLSEL 4C7D6527FF29F157 4C7D6527FF29F157 ggpps-1 2 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction ispu-1 1 3 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction