DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase. A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase. Proceedings of the National Academy of Sciences of the United States of America 2007 imex curation Muramoto K., Hirata K., Shinzawa-Itoh K., Yoko-o S., Yamashita E., Aoyama H., Tsukihara T., Yoshikawa S. Only protein-protein interactions bovin Bos taurus (Bovine) Bovine x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Muramoto K., Hirata K., Shinzawa-Itoh K., Yoko-o S., Yamashita E., Aoyama H., Tsukihara T., Yoshikawa S. DIP original experiment: DIP-261457X Proceedings of the National Academy of Sciences of the United States of America 2007 IMEx A histidine residue acting as a controlling site for dioxygen reduction and proton pumping by cytochrome c oxidase. cox7b_bovin Cytochrome c oxidase subunit 7B, mitochondrial COX7B Cytochrome c oxidase polypeptide VIIb IHQ protein protein bovin Bos taurus (Bovine) Bovine MFPLAKNALSRLRVQSIQQAVARQIHQKRAPDFHDKYGNAVLASGATFCVAVWVYMATQIGIEWNPSPVGRVTPKEWREQ DIP protein P13183 original sequence version: 116 D8EB7080C1CAEB16 cx6a2_bovin Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 COX6A Cytochrome c oxidase polypeptide VIa-heart Cytochrome c oxidase polypeptide VIb protein protein bovin Bos taurus (Bovine) Bovine MALPLKSLSRGLASAAKGDHGGTGARTWRFLTFGLALPSVALCTLNSWLHSGHRERPAFIPYHHLRIRTKPFSWGDGNHTFFHNPRVNPLPTGYEKP DIP protein P07471 original sequence version: 120 59B408A1B9B6AF4F cox8b_bovin Cytochrome c oxidase subunit 8B, mitochondrial COX8B COX8H Cytochrome c oxidase polypeptide VIII-heart Cytochrome c oxidase subunit 8-1 Cytochrome c oxidase subunit 8H IX VIIIb protein protein bovin Bos taurus (Bovine) Bovine MLRLAPTVRLLQAPLRGWAVPKAHITAKPAKTPTSPKEQAIGLSVTFLSFLLPAGWVLYHLDNYKKSSAA DIP protein P10175 original sequence version: 119 17BE70ADEC45FDD8 cox7c_bovin Cytochrome c oxidase subunit 7C, mitochondrial COX7C COX7CP1 Cytochrome c oxidase polypeptide VIIIA Cytochrome c oxidase polypeptide VIIc protein protein bovin Bos taurus (Bovine) Bovine MLGQSIRRFTTSVVRRSHYEEGPGKNIPFSVENKWRLLAMMTLFFGSGFAAPFFIVRHQLLKK DIP protein P00430 original sequence version: 125 C6A2AD5CC4E63C0B cox41_bovin Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 COX4 Cytochrome c oxidase subunit IV isoform 1 Cytochrome c oxidase polypeptide IV protein protein bovin Bos taurus (Bovine) Bovine MLATRVFSLIGRRAISTSVCVRAHGSVVKSEDYALPSYVDRRDYPLPDVAHVKNLSASQKALKEKEKASWSSLSIDEKVELYRLKFKESFAEMNRSTNEWKTVVGAAMFFIGFTALLLIWEKHYVYGPIPHTFEEEWVAKQTKRMLDMKVAPIQGFSAKWDYDKNEWKK DIP protein P00423 original sequence version: 114 76D2B2D15F8D02A1 cox3_bovin Cytochrome c oxidase subunit 3 MT-CO3 COIII COXIII Cytochrome c oxidase polypeptide III MTCO3 protein protein bovin Bos taurus (Bovine) Bovine MTHQTHAYHMVNPSPWPLTGALSALLMTSGLTMWFHFNSMTLLMIGLTTNMLTMYQWWRDVIRESTFQGHHTPAVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGIHPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGDRKHMLQALFITITLGVYFTLLQASEYYEAPFTISDGVYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS DIP protein P00415 original sequence version: 110 A521E76A9089B3FC cox5b_bovin Cytochrome c oxidase subunit 5B, mitochondrial COX5B Cytochrome c oxidase polypeptide Vb Cytochrome c oxidase polypeptide VIa protein protein bovin Bos taurus (Bovine) Bovine MASRLLRGVGALASQALRARGPNGVSVVRSMASGGGVPTDEEQATGLEREVMLAARKGQDPYNILAPKATSGTKEDPNLVPSITNKRIVGCICEEDNSTVIWFWLHKGEAQRCPSCGTHYKLVPHQLAH DIP protein P00428 original sequence version: 125 C78CE7552CE6C313 cx7a1_bovin Cytochrome c oxidase subunit 7A1, mitochondrial COX7A1 COX7A COX7AH Cytochrome c oxidase subunit VIIa-heart Cytochrome c oxidase subunit VIIa-muscle Cytochrome c oxidase subunit VIIIc protein protein bovin Bos taurus (Bovine) Bovine MRALRVSQALVRSFSSTARNRFENRVAEKQKLFQEDNGLPVHLKGGATDNILYRVTMTLCLGGTLYSLYCLGWASFPHKK DIP protein P07470 original sequence version: 122 A33FE89A867472A0 cx6b1_bovin Cytochrome c oxidase subunit 6B1 COX6B1 COX6B Cytochrome c oxidase polypeptide VII Cytochrome c oxidase subunit AED Cytochrome c oxidase subunit VIb isoform 1 protein protein bovin Bos taurus (Bovine) Bovine MAEDIQAKIKNYQTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWVSTWDDRRAEGTFPGKI DIP protein P00429 original sequence version: 119 A8933C01C71ACB8B cox2_bovin Cytochrome c oxidase subunit 2 MT-CO2 COII COXII MTCO2 Cytochrome c oxidase polypeptide II COX2 protein protein bovin Bos taurus (Bovine) Bovine MAYPMQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLSFDSYMIPTSELKPGELRLLEVDNRVVLPMEMTIRMLVSSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMSSRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEKWSASML DIP protein P68530 original sequence version: 86 C562D5B39FA9771A cox1_bovin Cytochrome c oxidase subunit 1 MT-CO1 COI COXI Cytochrome c oxidase polypeptide I MTCO1 protein protein bovin Bos taurus (Bovine) Bovine MFINRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMSQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMMWALGFIFLFTVGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFSGYTLNDTWAKIHFAIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTMWNTISSMGSFISLTAVMLMVFIIWEAFASKREVLTVDLTTTNLEWLNGCPPPYHTFEEPTYVNLK DIP protein P00396 original sequence version: 124 0D7C807D7FA3996C cox6c_bovin Cytochrome c oxidase subunit 6C COX6C Cytochrome c oxidase polypeptide VIc Cytochrome c oxidase subunit STA protein protein bovin Bos taurus (Bovine) Bovine MSTALAKPQMRGLLARRLRFHIVGAFMVSLGFATFYKFAVAEKRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK DIP protein P04038 original sequence version: 113 E063BDB1B7AE9E4C cox5a_bovin Cytochrome c oxidase subunit 5A, mitochondrial COX5A Cytochrome c oxidase polypeptide Va protein protein bovin Bos taurus (Bovine) Bovine MLGAAVRRCSVAAAAVARASPRGLLHPTPAPGQAAAVQSLRCYSHGSHETDEEFDARWVTYFNKPDIDAWELRKGMNTLVGYDLVPEPKIIDAALRACRRLNDFASAVRILEVVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV DIP protein P00426 original sequence version: 113 CE8FA765A8ABBA02 cox4i1-cox5a-3 1 9 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 13 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 10 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 3 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 8 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 14 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 6 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 11 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 4 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 5 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 2 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 7 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine 12 unspecified role unspecified role unspecified role unspecified role bovin Bos taurus (Bovine) Bovine physical association physical association