DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. PLoS biology 2007 imex curation Meinke G., Phelan P., Moine S., Bochkareva E., Bochkarev A., Bullock PA., Bohm A. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Meinke G., Phelan P., Moine S., Bochkareva E., Bochkarev A., Bullock PA., Bohm A. DIP original experiment: DIP-66500X PLoS biology 2007 IMEx The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. PLoS biology 2007 imex curation Meinke G., Phelan P., Moine S., Bochkareva E., Bochkarev A., Bullock PA., Bohm A. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Meinke G., Phelan P., Moine S., Bochkareva E., Bochkarev A., Bullock PA., Bohm A. DIP original experiment: DIP-66501X PLoS biology 2007 IMEx The crystal structure of the SV40 T-antigen origin binding domain in complex with DNA. lt_sv40 Large T antigen protein protein sv40 sv40 SV40 MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET 3E37D4BAFC5D59BD t_ag-1 2 3 unspecified role unspecified role unspecified role unspecified role OBD region 131-260 OBD region 131-260 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction t_ag-2 1 3 unspecified role unspecified role unspecified role unspecified role OBD region 131-260 OBD region 131-260 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli physical association physical association