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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>DIP</shortLabel>
        <fullName>Database of Interacting Proteins</fullName>
      </names>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="14681454" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1579232" refType="identity" refTypeAc="MI:0356"/>
      </xref>
      <attributeList>
        <attribute name="postaladdress">611 Young Drive East; Los Angeles CA 90095; USA</attribute>
        <attribute name="url" nameAc="MI:0614">http://dip.doe-mbi.ucla.edu/</attribute>
        <attribute name="contact-email" nameAc="MI:0634">dip@mbi.ucla.edu</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Dominance of SOX9 function over RUNX2 during skeletogenesis.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="17142326" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0605170103" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15613744" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-23996" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Dominance of SOX9 function over RUNX2 during skeletogenesis.</attribute>
            <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
            <attribute name="publication year" nameAc="MI:0886">2006</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Zhou G.,  Zheng Q.,  Engin F.,  Munivez E.,  Chen Y.,  Sebald E.,  Krakow D.,  Lee B.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="imex" dbAc="MI:0670" id="IM-23996" refType="imex-primary" refTypeAc="MI:0662"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-264246X" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="pubmed" dbAc="MI:0446" id="17142326" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="doi" dbAc="MI:0574" id="10.1073/pnas.0605170103" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>pull down</shortLabel>
            <fullName>pull down</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0096" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1223" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>autoradiography</shortLabel>
            <fullName>autoradiography</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1372407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Zhou G., Zheng Q., Engin F., Munivez E., Chen Y., Sebald E., Krakow D., Lee B.</attribute>
          <attribute name="comment" nameAc="MI:0612">DIP original experiment: DIP-264246X</attribute>
          <attribute name="journal" nameAc="MI:0885">Proceedings of the National Academy of Sciences of the United States of America</attribute>
          <attribute name="publication year" nameAc="MI:0886">2006</attribute>
          <attribute name="curation depth" nameAc="MI:0955">IMEx</attribute>
          <attribute name="title" nameAc="MI:1091">Dominance of SOX9 function over RUNX2 during skeletogenesis.</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>runx2_human</shortLabel>
          <fullName>Runt-related transcription factor 2</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Oncogene AML-3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Polyomavirus enhancer-binding protein 2 alpha A subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SL3-3 enhancer factor 1 alpha A subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SL3/AKV core-binding factor alpha A subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Osteoblast-specific transcription factor 2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Core-binding factor subunit alpha-1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Acute myeloid leukemia 3 protein</alias>
          <alias type="gene name" typeAc="MI:0301">RUNX2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">AML3</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CBFA1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">OSF2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">PEBP2A</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q13950" version="SP_71" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28971669" refType="intact-secondary"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000360493" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495497" version="SP_206" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14614" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O14615" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="O95181" version="SP_71" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-976402" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000359524"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000352514"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000371432"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000360486"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000371436"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000360491"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000360493"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000495497"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000124813" version="SP_206" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000371438" version="SP_206" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000647337" version="SP_206" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000785" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000978" version="SP_206"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001228" version="SP_206"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001649" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0001958" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002051" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002062" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002063" version="SP_206"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030217" version="SP_206"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030509" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071773" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901522" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000040" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008967" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012346" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013524" version="SP_206"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013711" version="SP_206"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027384" version="SP_206"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q13950" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042487" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_206"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VG8" version="SP_206"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VGD" version="SP_206"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VGE" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045595" version="SP_206"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045669" version="SP_206"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6VGG" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2032785" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8878166" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939246" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8939902" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8940973" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941284" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941326" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941332" version="SP_206"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941333" version="SP_206"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001015051.3"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001019801.3"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-36707N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MASNSLFSTVTPCQQNFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQKLDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQSSPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISDDDTATSDFCLWPSTLSKKSQAGASELGPFSDPRQFPSISSLTESRFSNPRMHYPATFTYTPPVTSGMSLGMSATTHYHTYLPPPYPGSSQSQSGPFQTSSTPYLYYGTSSGSYQFPMVPGGDRSPSRMLPPCTTTSNGSTLLNPNLPNQNDGVDADGSHSSSPTVLNSSGRMDESVWRPY</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q13950 original sequence version: 155</attribute>
          <attribute name="remark-internal">DIP protein Q13950 original sequence version: 138</attribute>
          <attribute name="remark-internal">DIP protein Q13950 original sequence version: 108</attribute>
          <attribute name="remark-internal">DIP protein Q13950 original sequence version: 157</attribute>
          <attribute name="remark-internal">DIP protein Q13950 original sequence version: 135</attribute>
          <attribute name="remark-internal">DIP protein Q13950-1 original sequence version: 135</attribute>
          <attribute name="crc64">44C4F3867D6F3EB1</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>sox9_human</shortLabel>
          <fullName>Transcription factor SOX-9</fullName>
          <alias type="gene name" typeAc="MI:0301">SOX9</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P48436" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000245479" version="SP_209" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q53Y80" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000125398" version="SP_209" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000245479" version="SP_209" refType="transcript"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030857" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030858" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030879" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030903" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030916" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031018" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032331" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032332" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032808" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032991" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034236" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0034504" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035019" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0002053" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0035622" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042127" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043066" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043425" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043491" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042981" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043565" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045662" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045668" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045732" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045892" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045893" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046322" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046533" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048709" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050679" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0050680" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051216" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060008" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060009" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060018" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060041" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060174" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060221" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060441" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060487" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060517" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060532" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060534" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060729" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0060784" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061036" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061046" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061138" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0061145" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0065003" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070168" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070371" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070384" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070542" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071260" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071300" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071347" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071364" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071504" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071560" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071773" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072034" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072190" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072193" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072197" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072289" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090090" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090103" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090184" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090190" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097065" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097157" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0098609" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1901203" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902732" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902894" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1904864" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990837" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000020" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000138" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000741" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000794" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001054" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR009071" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022151" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR029548" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036910" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1S9M" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SX9" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4EUW" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3769402" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8878166" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9690406" version="SP_209"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_000337.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-61319N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MNLLDPFMKMTDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESEEDKFPVCIREAVSQVLKGYDWTLVPMPVRVNGSSKNKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKNGQAEAEEATEQTHISPNAIFKALQADSPHSSSGMSEVHSPGEHSGQSQGPPTPPTTPKTDVQPGKADLKREGRPLPEGGRQPPIDFRDVDIGELSSDVISNIETFDVNEFDQYLPPNGHPGVPATHGQVTYTGSYGISSTAATPASAGHVWMSKQQAPPPPPQQPPQAPPAPQAPPQPQAAPPQQPAAPPQQPQAHTLTTLSSEPGQSQRTHIKTEQLSPSHYSEQQQHSPQQIAYSPFNLPHYSPSYPPITRSQYDYTDHQNSSSYYSHAAGQGTGLYSTFTYMNPAQRPMYTPIADTSGVPSIPQTHSPQHWEQPVYTQLTRP</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P48436 original sequence version: 154</attribute>
          <attribute name="crc64">9289CFBB8D6631A2</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-23996-1">
        <names>
          <shortLabel>runx2-sox9-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="dip" dbAc="MI:0465" id="DIP-198438E" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-15613763" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0465" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-23996-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>Region 1-304</shortLabel>
                  <fullName>Region 1-304</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-15613771" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>sufficient to bind</shortLabel>
                    <fullName>sufficient binding region</fullName>
                    <alias type="synonym" typeAc="MI:1041">sufficient to bind</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0442" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608899" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureDetectionMethod>
                  <names>
                    <shortLabel>deletion analysis</shortLabel>
                    <fullName>deletion analysis</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0033" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456769" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureDetectionMethod>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="1"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="304"/>
                  </featureRange>
                </featureRangeList>
              </feature>
              <feature id="7">
                <names>
                  <shortLabel>35S-label</shortLabel>
                  <fullName>35S-label</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-15613773" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>35s radiolabel</shortLabel>
                    <fullName>35s radiolabel</fullName>
                    <alias type="go synonym" typeAc="MI:0303">35S</alias>
                    <alias type="go synonym" typeAc="MI:0303">s35 radiolabelled</alias>
                    <alias type="go synonym" typeAc="MI:0303">S35</alias>
                    <alias type="synonym" typeAc="MI:1041">s35 radiolabelled</alias>
                    <alias type="synonym" typeAc="MI:1041">35S</alias>
                    <alias type="synonym" typeAc="MI:1041">S35</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0371" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608954" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="-1">
                <names>
                  <shortLabel>in vitro</shortLabel>
                  <fullName>In vitro</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
          <participant id="8">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="9">
                <names>
                  <shortLabel>GST-tag</shortLabel>
                  <fullName>GST-tag</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-15613768" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>gst tag</shortLabel>
                    <fullName>glutathione s tranferase tag</fullName>
                    <alias type="go synonym" typeAc="MI:0303">glutathione S-tranferase tag</alias>
                    <alias type="synonym" typeAc="MI:1041">glutathione S-tranferase tag</alias>
                    <alias type="synonym" typeAc="MI:1041">gst tag</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0519" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456510" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>n-term range</shortLabel>
                        <fullName>n-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">n-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>n-term range</shortLabel>
                        <fullName>n-terminal range</fullName>
                        <alias type="synonym" typeAc="MI:1041">n-term range</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:1040" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2929795" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14760721" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="562">
                <names>
                  <shortLabel>ecolx</shortLabel>
                  <fullName>Escherichia coli</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
      </interaction>
    </interactionList>
  </entry>
</entrySet>