DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. Only protein-protein interactions in vitro In vitro solid state nmr solid state nmr ssnmr solid state nmr predetermined predetermined participant predetermined Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. DIP original experiment: DIP-264042X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. Only protein-protein interactions in vitro In vitro fluorescence spectr classical fluorescence spectroscopy fluorescence spectr predetermined predetermined participant predetermined Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. DIP original experiment: DIP-264043X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. Only protein-protein interactions in vitro In vitro tem transmission electron microscopy tem predetermined predetermined participant predetermined Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. DIP original experiment: DIP-264041X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. General structural motifs of amyloid protofilaments. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. Only protein-protein interactions in vitro In vitro light scattering light scattering predetermined predetermined participant predetermined Ferguson N., Becker J., Tidow H., Tremmel S., Sharpe TD., Krause G., Flinders J., Petrovich M., Berriman J., Oschkinat H., Fersht AR. DIP original experiment: DIP-264040X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx General structural motifs of amyloid protofilaments. tcrg1_human Transcription elongation regulator 1 TATA box-binding protein-associated factor 2S Transcription factor CA150 TCERG1 CA150 TAF2S protein protein human Homo sapiens Human MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK DIP protein O14776 original sequence version: 133 5F0A0C3A07EBF00F tcerg1-1 2 5 unspecified role unspecified role unspecified role unspecified role Region 427-439 Region 427-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction tcerg1-2 4 5 unspecified role unspecified role unspecified role unspecified role Region 427-439 Region 427-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction tcerg1-3 3 5 unspecified role unspecified role unspecified role unspecified role Region 427-439 Region 427-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction tcerg1-4 1 5 unspecified role unspecified role unspecified role unspecified role Region 427-464 Region 427-464 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain in vitro In vitro direct interaction direct interaction