DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature 2006 imex curation Paton AW., Beddoe T., Thorpe CM., Whisstock JC., Wilce MC., Rossjohn J., Talbot UM., Paton JC. Only protein-protein interactions in vitro In vitro protease assay protease assay predetermined predetermined participant predetermined Paton AW., Beddoe T., Thorpe CM., Whisstock JC., Wilce MC., Rossjohn J., Talbot UM., Paton JC. DIP original experiment: DIP-254001X Nature 2006 IMEx AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. bip_bovin Endoplasmic reticulum chaperone BiP HSPA5 GRP78 78 kDa glucose-regulated protein Binding-immunoglobulin protein Heat shock protein 70 family protein 5 Heat shock protein family A member 5 Immunoglobulin heavy chain-binding protein protein protein bovin Bos taurus (Bovine) Bovine MKLSLVAAVLLLLLGTARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDVGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTSEEEAADKDEL DIP protein Q0VCX2 original sequence version: 54 93B4C3D46A441066 suba_ecolx Subtilase cytotoxin subunit A subA protein protein ecolx Escherichia coli MLKILWTYILFLLFISASARAEKPWYFDAIGLTETTMSLTDKNTPVVVSVVDSGVAFIGGLSDSEFAKFSFTQDGSPFPVKKSEALYIHGTAMASLIASRYGIYGVYPHALISSRRVIPDGVQDSWIRAIESIMSNVFLAPGEEKIINISGGQKGVASASVWTELLSRMGRNNDRLIVAAVGNDGADIRKLSAQQRIWPAAYHPVSSVNKKQDPVIRVAALAQYRKGETPVLHGGGITGSRFGNNWVDIAAPGQNITFLRPDAKTGTGSGTSEATAIVSGVLAAMTSCNPRATATELKRTLLESADKYPSLVDKVTEGRVLNAEKAISMFCKKNYIPVRQGRMSEEL DIP protein Q6EZC2 original sequence version: 41 hspa5-suba-1 1 3 enzyme enzyme unspecified role unspecified role ecolx Escherichia coli 2 enzyme target enzyme target substrate substrate unspecified role unspecified role bovin Bos taurus (Bovine) Bovine protein cleavage protein cleavage