DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 2006 imex curation Saleh M., Mathison JC., Wolinski MK., Bensinger SJ., Fitzgerald P., Droin N., Ulevitch RJ., Green DR., Nicholson DW. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Saleh M., Mathison JC., Wolinski MK., Bensinger SJ., Fitzgerald P., Droin N., Ulevitch RJ., Green DR., Nicholson DW. DIP original experiment: DIP-254044X Nature 2006 IMEx Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 2006 imex curation Saleh M., Mathison JC., Wolinski MK., Bensinger SJ., Fitzgerald P., Droin N., Ulevitch RJ., Green DR., Nicholson DW. Only protein-protein interactions human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip predetermined predetermined participant predetermined Saleh M., Mathison JC., Wolinski MK., Bensinger SJ., Fitzgerald P., Droin N., Ulevitch RJ., Green DR., Nicholson DW. DIP original experiment: DIP-254043X Nature 2006 IMEx Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. casp1_human Caspase-1 Interleukin-1 beta convertase Interleukin-1 beta-converting enzyme p45 CASP1 IL1BC IL1BCE protein protein human Homo sapiens Human MADKVLKEKRKLFIRSMGEGTINGLLDELLQTRVLNKEEMEKVKRENATVMDKTRALIDSVIPKGAQACQICITYICEEDSYLAGTLGLSADQTSGNYLNMQDSQGVLSSFPAPQAVQDNPAMPTSSGSEGNVKLCSLEEAQRIWKQKSAEIYPIMDKSSRTRLALIICNEEFDSIPRRTGAEVDITGMTMLLQNLGYSVDVKKNLTASDMTTELEAFAHRPEHKTSDSTFLVFMSHGIREGICGKKHSEQVPDILQLNAIFNMLNTKNCPSLKDKPKVIIIQACRGDSPGVVWFKDSVGVSGNLSLPTTEEFEDDAIKKAHIEKDFIAFCSSTPDNVSWRHPTMGSVFIGRLIEHMQEYACSCDVEEIFRKVRFSFEQPDGRAQMPTTERVTLTRCFYLFPGH DIP protein P29466 original sequence version: 155 DIP protein P29466-1 original sequence version: 169 DIP protein P29466 original sequence version: 169 DIP protein P29466 original sequence version: 163 DIP protein P29466 original sequence version: 101 DIP protein P29466 original sequence version: 160 DIP protein P29466 original sequence version: 184 ABF33CF33CC71584 caspc_rat Caspase-12 Casp12 protein protein rat Rattus norvegicus (Rat) Rat MAAKRTHERDPIYKIKGLAKDMLDGVFDDLMDKNVLNGDELLKIGEGASLILSKAENLVESFFEKTEMAGKIFAGHIANSDKQLSLQFPSDDEEDELQKMFTPSSASESRGKVEDEEMEVNVGVAHASHLMLTVPQGIQSTEVQDSLKLCSRDWFCTMKTERAEEIYPVMEKEGRTRLALIICNKKFDYLFDRDDAETDILNMKELLQNLGYSVVIKENLTAQEMETELMKFAGRPEHQSSDSTFLVFMSHGILEGICGVKHRNKKPDVLHDDTIFTIFNNSNCPSLRNKPKILIMQACRGRHTGTIWVSTSKGIATADTDEECVLSHRWNNSITKAHVETDFIAFKSSTPHNISWKVGKSGSLFISKLIDCFKKYCWCYHLEEIFRKVQYSFEVPGELTQMPTIERVSMTRYFYLFPGN DIP protein Q920D5 original sequence version: 79 DIP protein Q920D5 original sequence version: 40 E00809BBC61461AC casp5_human Caspase-5 CASP5 ICH3 Protease ICH-3 Protease TY ICE(rel)-III protein protein human Homo sapiens Human MAEDSGKKKRRKNFEAMFKGILQSGLDNFVINHMLKNNVAGQTSIQTLVPNTDQKSTSVKKDNHKKKTVKMLEYLGKDVLHGVFNYLAKHDVLTLKEEEKKKYYDTKIEDKALILVDSLRKNRVAHQMFTQTLLNMDQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRDSPASLALISSQSSENLEADSVCKIHEEKDFIAFCSSTPHNVSWRDRTRGSIFITELITCFQKYSCCCHLMEIFRKVQKSFEVPQAKAQMPTIERATLTRDFYLFPGN DIP protein P51878 original sequence version: 126 C5257C2BF15EB6D5 casp1-casp12-1 2 3 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 4 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association casp5-casp12-1 1 5 unspecified role unspecified role bait bait Flag-tag Flag-tag flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged n-term range n-terminal range n-term range n-term range n-terminal range n-term range human Homo sapiens Human 4 unspecified role unspecified role prey prey human Homo sapiens Human physical association physical association