DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Nature 2006 imex curation Ali MM., Roe SM., Vaughan CK., Meyer P., Panaretou B., Piper PW., Prodromou C., Pearl LH. Only protein-protein interactions in vitro In vitro x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ali MM., Roe SM., Vaughan CK., Meyer P., Panaretou B., Piper PW., Prodromou C., Pearl LH. DIP original experiment: DIP-254042X Nature 2006 IMEx Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. Nature 2006 imex curation Ali MM., Roe SM., Vaughan CK., Meyer P., Panaretou B., Piper PW., Prodromou C., Pearl LH. Only protein-protein interactions ecolx Escherichia coli x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Ali MM., Roe SM., Vaughan CK., Meyer P., Panaretou B., Piper PW., Prodromou C., Pearl LH. DIP original experiment: DIP-254041X Nature 2006 IMEx Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex. sba1_yeast Co-chaperone protein SBA1 YKL518 YKL117W SBA1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSDKVINPQVAWAQRSSTTDPERNYVLITVSIADCDAPELTIKPSYIELKAQSKPHVGDENVHHYQLHIDLYKEIIPEKTMHKVANGQHYFLKLYKKDLESEYWPRLTKEKVKYPYIKTDFDKWVDEDEQDEVEAEGNDAAQGMDFSQMMGGAGGAGGAGGMDFSQMMGGAGGAGSPDMAQLQQLLAQSGGNLDMGDFKENDEEDEEEEIEPEVKA C51CDE30BF2FA945 C51CDE30BF2FA945 hsp82_yeast ATP-dependent molecular chaperone HSP82 HSP90 YPL240C HSP82 Heat shock protein Hsp90 heat-inducible isoform 82 kDa heat shock protein protein protein yeast Saccharomyces cerevisiae Baker's yeast MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTEMEEVD D7C35676D668FB63 D7C35676D668FB63 hsp90-1 2 4 unspecified role unspecified role unspecified role unspecified role Region 273-709 Region 273-709 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli direct interaction direct interaction hsp90-sba1-1 1 3 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli 4 unspecified role unspecified role unspecified role unspecified role ecolx Escherichia coli direct interaction direct interaction