DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Sato M., Cismowski MJ., Toyota E., Smrcka AV., Lucchesi PA., Chilian WM., Lanier SM. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Sato M., Cismowski MJ., Toyota E., Smrcka AV., Lucchesi PA., Chilian WM., Lanier SM. DIP original experiment: DIP-262498X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. Proceedings of the National Academy of Sciences of the United States of America 2006 imex curation Sato M., Cismowski MJ., Toyota E., Smrcka AV., Lucchesi PA., Chilian WM., Lanier SM. Only protein-protein interactions in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Sato M., Cismowski MJ., Toyota E., Smrcka AV., Lucchesi PA., Chilian WM., Lanier SM. DIP original experiment: DIP-262499X Proceedings of the National Academy of Sciences of the United States of America 2006 IMEx Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma. gbb2_rat Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Gnb2 G protein subunit beta-2 Transducin beta chain 2 protein protein rat Rattus norvegicus (Rat) Rat MSELEQLRQEAEQLRNQIRDARKACGDSTLTQITAGLDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN DIP protein P54313 original sequence version: 116 fndc1_rat Fibronectin type III domain-containing protein 1 Fndc1 Ags8 Activator of G-protein signaling 8 protein protein rat Rattus norvegicus (Rat) Rat MAPEARASPRLLLRAALLLLAALLPVASSAGPPVDHPLKPRHVKLLSANMGLKVTWDPPKDATSRPVEHYNIAYGKSLKSLKSIKVNAETHSFLIKDVEKEVPNKPLRMRVRASDDRLSVAWKAPRLSGAKSPRRSRGFLLGYGESGRKMNYVPLTRDERSHEIKKLASESVYVVSLQSTNSQGQSQPVYRAALTKRKNAEEDELDVPEDISVRVMSSQSVLVAWVDPLVEKQKRVVASRQYTVRYREKGESARWDYKQVSNRRALVDSLIPDTVYEFAVRISQGERDGKWSASVFQRTPESAPTTAPENLRVWPVNGKPTVVTVSWDALPESEGKVKEYILSYAPALKPFGAKSLTFSGHTTSALVDGLQPGERYLFKIRATNRRGQGPHSKAFIVAIPTTSSTEASVQPNGRDNGKPEKPQQPSSSAPKVAASSQHMPPAKNVKDALSDLKNKIQTNGVAPGRTQLHSKVGELDPQSTEVTGEEELDSLENPRSSRLETLNQKQPLRVPSRSGHGALAPGRTPARAGLPVLSRKEGMDRRGPSLDPHPHPRVEPSASSAYHQLSSTDNDSVDRKEDDQAGSPDPKAASSGSSPKNPGRSRPTSAPSRHAASNMLRDKSRVHPGTKAASSSTSRQSHSSTSEEDSSAQPSRHFPLHRGSSTSPLSRGWKDRQDTHASSSHTTSRTASSSHPSALTEGSEEEDGGADSDRAAEDTIRRAEATAQIQQTRPGLGHFSLIRNKPFTPHSRNPNRFPRLRGPRLQPSVSPQSTSASKVLTRSPSLPASHTRPGSDVYGDGEDEEPLPATVINDRTPSYPRHPISGSSDTLRRGPQRGASLYRKEPIPENSKAAGADVPPGGRSPLSSKAQGFQQSTTDEGAPQTSPASTSRQPSPARPPASRSQPSPGSTVPRRMTPDRSSELSSSQSKDRSLSQPKLSVAHAGHDHPHTANSRGVLPSAPQNQNEGAQSTYEDNSTEIEGPDSRTPTHSARAKDTTPPILKPRQVGSQSWSSDNRPQPSQAGASERPIRPGSTHPRAQVPGRAGVQATSVKKVSPSKRPLPLESQQSVFAEEEEENEGMLKGKEDSLSTSVKKWPSSSSPRDKYADRNLDKDKAAIGLLVQEENTVPGRRPPGSPAIASHPSTRHQPRNPATASPIANTHSWPRYTTRAPSSYSSTTPMLSLRQRMQRRFRTPVSRQPPPPRPVLTPGYNGRPNAEENIPPGSIGKPNGQRIINGPQGTKWVVDLDRGLVLNAEGRYLQDSHGNPLRVRLGGDGRTIVDLGGTPMVSPDGLPLFGQGRHGKPVASAQDKPILSLGGKPLVGLEVVRTTTQVPTTTMPPSTTTTTVPPTTTLPPTTTTTRRTTTTRRTTTTRRPTTTTRATRRTTTTTTTPEPTTPSPTCPPGTLEHRDEAGNLIMGSNGIPECYPEEDDFSGLEIDTALPTEEDYVVYDDDYGLETTRPPTSTMPSTTAATPKVVPEQGTVSSFPEEEFDLAGKRRFVAPYVTYLSKDPAAPCSLTDALDHFQVESLDELIPNDLTKNDLPPQHAPRNITVVAMEGCHSFVIVDWNKAIPGDVVTGYLVYSASYEDFIRNKWSTQTSSVTHLPIENLKPNTRYYFKVQAKNPHGYGPVSPSVSFVTESDNPLLVVRPPGGEPIWIPFAFKHDPGYTDCHGRQYVKRTWYKKFVGVVLCNSLRYKIYLSDNLKDTFYSIGDSWGRGEDHCQFVDSHLDGRTGPQSYVEALPTIQGYYRQYRQEPVSFGHIGFGTPYYYVGWYECGVSIPGKW DIP protein Q2Q0I9 original sequence version: 65 gbb1_rat Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Transducin beta chain 1 Gnb1 protein protein rat Rattus norvegicus (Rat) Rat MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN DIP protein P54311 original sequence version: 123 DIP protein P54311 original sequence version: 96 896CBD32D2686598 fndc1-gnb1-1 1 5 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 4 unspecified role unspecified role bait bait Region 1359-1730 Region 1359-1730 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association fndc1-gnb2-1 2 3 unspecified role unspecified role prey prey spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 4 unspecified role unspecified role bait bait Region 1359-1730 Region 1359-1730 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecolx Escherichia coli physical association physical association