DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66113X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66105X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66112X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66104X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66106X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-261535X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66114X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions human Homo sapiens Human protein kinase assay protein kinase assay ms participant Identification by mass spectrometry ms participant Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66110X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay predetermined predetermined participant predetermined Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66111X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66107X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions human Homo sapiens Human protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66109X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. Nature structural & molecular biology 2006 imex curation Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. Only protein-protein interactions in vitro In vitro protein kinase assay protein kinase assay antibody detection identification by antibody antibody detection Larochelle S., Batliner J., Gamble MJ., Barboza NM., Kraybill BC., Blethrow JD., Shokat KM., Fisher RP. DIP original experiment: DIP-66108X Nature structural & molecular biology 2006 IMEx Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics. cdk2_human Cyclin-dependent kinase 2 CDK2 p33 protein kinase Cell division protein kinase 2 CDKN2 protein protein human Homo sapiens Human MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL DIP protein P24941 original sequence version: 142 DIP protein P24941 original sequence version: 118 DIP protein P24941 original sequence version: 143 DIP protein P24941 original sequence version: 144 DIP protein P24941 original sequence version: 152 DIP protein P24941 original sequence version: 182 DIP protein P24941-1 original sequence version: 204 DIP protein P24941 original sequence version: 90 DIP protein P24941 original sequence version: 190 DIP protein P24941 original sequence version: 168 F90A0F4E70910B51 cdk1_human Cyclin-dependent kinase 1 p34 protein kinase Cell division protein kinase 1 CDK1 CDC2 Cell division control protein 2 homolog CDC28A CDKN1 P34CDC2 protein protein human Homo sapiens Human MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM DIP protein P06493 original sequence version: 185 DIP protein P06493 original sequence version: 162 DIP protein P06493 original sequence version: 184 DIP protein P06493 original sequence version: 97 DIP protein P06493 original sequence version: 192 942D79448EFE490A cdk4_human Cyclin-dependent kinase 4 CDK4 Cell division protein kinase 4 PSK-J3 protein protein human Homo sapiens Human MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGNPE DIP protein P11802 original sequence version: 177 DIP protein P11802 original sequence version: 135 DIP protein P11802 original sequence version: 136 DIP protein P11802 original sequence version: 200 DIP protein P11802 original sequence version: 86 0916A0C07403A33A q6iaw3_human CDK5 protein protein human Homo sapiens Human MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNPLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP DIP protein Q6IAW3 original sequence version: 25 p21127-12 Cyclin-dependent kinase 11B PITSLRE serine/threonine-protein kinase CDC2L1 PITSLREA PK58 CDK11B CDC2L1 CDK11 Cell division cycle 2-like protein kinase 1 Galactosyltransferase-associated protein kinase p58/GTA p58 CLK-1 Cell division protein kinase 11B CDK11-p58 protein protein human Homo sapiens Human MSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF Produced by alternative initiation at Met-357 of isoform SV9 via an internal ribosomal entry site (IRES). DIP protein P21127-12 original sequence version: 75 2008B90F6CE66EF6 spt5h_human Transcription elongation factor SPT5 DRB sensitivity-inducing factor large subunit DRB sensitivity-inducing factor 160 kDa subunit Tat-cotransactivator 1 protein SUPT5H SPT5 SPT5H protein protein human Homo sapiens Human MSDSEDSNFSEEEDSERSSDGEEAEVDEERRSAAGSEKEEEPEDEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKEEIEASNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMSLKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVVTESTGKEREHNFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMYGKVVTVRHQAVTRKKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHLFRSFAFLHCKKLVENGGMFVCKTRHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMDLDEQLKILNLRFLGKLLEA DIP protein O00267 original sequence version: 130 DIP protein O00267 original sequence version: 91 DIP protein O00267 original sequence version: 131 DIP protein O00267-1 original sequence version: 150 DIP protein O00267 original sequence version: 44 EC3F402A670A5B7D cdk19_human Cyclin-dependent kinase 19 CDK19 CDC2-related protein kinase 6 Death-preventing kinase Cyclin-dependent kinase 11 CDK11 KIAA1028 CDC2L6 Cell division cycle 2-like protein kinase 6 Cell division protein kinase 19 protein protein human Homo sapiens Human MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY DIP protein Q9BWU1 original sequence version: 43 DIP protein Q9BWU1 original sequence version: 124 D9EED1BBB582EABA cdk7_human Cyclin-dependent kinase 7 CDK7 MO15 CAK CAK1 TFIIH basal transcription factor complex kinase subunit 39 kDa protein kinase CDKN7 STK1 Cell division protein kinase 7 CDK-activating kinase 1 Serine/threonine-protein kinase 1 protein protein human Homo sapiens Human MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF DIP protein P50613 original sequence version: 126 DIP protein P50613 original sequence version: 78 0A94BFA7DD416CEB rpb1_human DNA-directed RNA polymerase II subunit RPB1 POLR2A DNA-directed RNA polymerase II subunit A DNA-directed RNA polymerase III largest subunit POLR2 RNA-directed RNA polymerase II subunit RPB1 protein protein human Homo sapiens Human MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSVRPAVVMQGSARNQDDLTHKLADIVKINNQLRRNEQNGAAAHVIAEDVKLLQFHVATMVDNELPGLPRAMQKSGRPLKSLKQRLKGKEGRVRGNLMGKRVDFSARTVITPDPNLSIDQVGVPRSIAANMTFAEIVTPFNIDRLQELVRRGNSQYPGAKYIIRDNGDRIDLRFHPKPSDLHLQTGYKVERHMCDGDIVIFNRQPTLHKMSMMGHRVRILPWSTFRLNLSVTTPYNADFDGDEMNLHLPQSLETRAEIQELAMVPRMIVTPQSNRPVMGIVQDTLTAVRKFTKRDVFLERGEVMNLLMFLSTWDGKVPQPAILKPRPLWTGKQIFSLIIPGHINCIRTHSTHPDDEDSGPYKHISPGDTKVVVENGELIMGILCKKSLGTSAGSLVHISYLEMGHDITRLFYSNIQTVINNWLLIEGHTIGIGDSIADSKTYQDIQNTIKKAKQDVIEVIEKAHNNELEPTPGNTLRQTFENQVNRILNDARDKTGSSAQKSLSEYNNFKSMVVSGAKGSKINISQVIAVVGQQNVEGKRIPFGFKHRTLPHFIKDDYGPESRGFVENSYLAGLTPTEFFFHAMGGREGLIDTAVKTAETGYIQRRLIKSMESVMVKYDATVRNSINQVVQLRYGEDGLAGESVEFQNLATLKPSNKAFEKKFRFDYTNERALRRTLQEDLVKDVLSNAHIQNELEREFERMREDREVLRVIFPTGDSKVVLPCNLLRMIWNAQKIFHINPRLPSDLHPIKVVEGVKELSKKLVIVNGDDPLSRQAQENATLLFNIHLRSTLCSRRMAEEFRLSGEAFDWLLGEIESKFNQAIAHPGEMVGALAAQSLGEPATQMTLNTFHYAGVSAKNVTLGVPRLKELINISKKPKTPSLTVFLLGQSARDAERAKDILCRLEHTTLRKVTANTAIYYDPNPQSTVVAEDQEWVNVYYEMPDFDVARISPWLLRVELDRKHMTDRKLTMEQIAEKINAGFGDDLNCIFNDDNAEKLVLRIRIMNSDENKMQEEEEVVDKMDDDVFLRCIESNMLTDMTLQGIEQISKVYMHLPQTDNKKKIIITEDGEFKALQEWILETDGVSLMRVLSEKDVDPVRTTSNDIVEIFTVLGIEAVRKALERELYHVISFDGSYVNYRHLALLCDTMTCRGHLMAITRHGVNRQDTGPLMKCSFEETVDVLMEAAAHGESDPMKGVSENIMLGQLAPAGTGCFDLLLDAEKCKYGMEIPTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPASPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN DIP protein P24928 original sequence version: 108 DIP protein P24928 original sequence version: 147 DIP protein P24928 original sequence version: 158 DIP protein P24928 original sequence version: 157 DIP protein P24928 original sequence version: 179 DIP protein P24928 original sequence version: 181 DIP protein P24928 original sequence version: 161 DIP protein P24928 original sequence version: 175 DIP protein P24928-1 original sequence version: 175 DIP protein P24928 original sequence version: 68 DIP protein P24928 original sequence version: 116 28D6FD25693A6472 cdk9_human Cyclin-dependent kinase 9 CDK9 CDC2L4 Cell division protein kinase 9 Serine/threonine-protein kinase PITALRE Cell division cycle 2-like protein kinase 4 C-2K TAK Tat-associated kinase complex catalytic subunit protein protein human Homo sapiens Human MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFPITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVKFTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNSQPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLALISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDPAQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNPATTNQTEFERVF DIP protein P50750 original sequence version: 100 DIP protein P50750 original sequence version: 115 DIP protein P50750-1 original sequence version: 119 DIP protein P50750 original sequence version: 170 DIP protein P50750 original sequence version: 184 DIP protein P50750-1 original sequence version: 144 DIP protein P50750 original sequence version: 70 DIP protein P50750 original sequence version: 120 69E851CC6F7A0388 cdk7-polr2a-1 4 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 15:25:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 17:40:34 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm 21 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human direct interaction direct interaction cdk1-cdk7-1 2 14 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 20:05:48 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 19:24:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk2-cdk7-2 5 13 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 15:34:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 19:19:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk4-cdk7-1 10 15 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 20:20:49 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 18:46:05 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk5-cdk7-1 12 16 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 16:36:19 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 19:42:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk19-cdk7-1 11 19 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 17:12:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 16:22:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk7-supt5h-1 8 18 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 19:29:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 20:19:54 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk11b-cdk7-1 9 17 enzyme target enzyme target substrate substrate unspecified role unspecified role in vitro In vitro 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 16:41:02 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 17:29:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk7-supt5h-2 1 18 enzyme target enzyme target substrate substrate unspecified role unspecified role 844-1087 binding region 844-1087 binding region sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 20:19:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 16:49:18 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk9-supt5h-1 7 18 enzyme target enzyme target substrate substrate unspecified role unspecified role 720-830 binding region 720-830 binding region sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 22 enzyme enzyme unspecified role unspecified role spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk7-supt5h-3 3 18 enzyme target enzyme target substrate substrate unspecified role unspecified role 720-830 binding region 720-830 binding region sufficient to bind sufficient binding region sufficient to bind full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 15:18:47 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 19:03:30 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction cdk4-cdk7-2 6 15 enzyme target enzyme target substrate substrate unspecified role unspecified role human Homo sapiens Human 20 enzyme enzyme unspecified role unspecified role P50613:p.Phe91Gly F91G mutation mutation mutation full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain F G This feature has been corrected as a result of our quality control procedures. The original label was 'F91G mutation'. Wed May 02 15:14:52 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe91gly' Tue Jun 30 15:42:04 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe91Gly' spofr Spodoptera frugiperda (Fall armyworm) Fall armyworm direct interaction direct interaction 1 nodeMerge04 2014-06-30