DIP Database of Interacting Proteins 611 Young Drive East; Los Angeles CA 90095; USA http://dip.doe-mbi.ucla.edu/ dip@mbi.ucla.edu Recruitment of the priming protein pTP and DNA binding occur by overlapping Oct-1 POU homeodomain surfaces. Recruitment of the priming protein pTP and DNA binding occur by overlapping Oct-1 POU homeodomain surfaces. The EMBO journal 2002 imex curation de Jong RN., Mysiak ME., Meijer LA., van der Linden M., van der Vliet PC. Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined de Jong RN., Mysiak ME., Meijer LA., van der Linden M., van der Vliet PC. DIP original experiment: DIP-266765X The EMBO journal 2002 IMEx Recruitment of the priming protein pTP and DNA binding occur by overlapping Oct-1 POU homeodomain surfaces. p14859-1 POU domain, class 2, transcription factor 1 NF-A1 Octamer-binding protein 1 Octamer-binding transcription factor 1 POU2F1 OCT1 OTF1 protein protein human Homo sapiens Human MNNPSETSKPSMESGDGNTGTQTNGLDFQKQPVPVGGAISTAQAQAFLGHLHQVQLAGTSLQAAAQSLNVQSKSNEESGDSQQPSQPSQQPSVQAAIPQTQLMLAGGQITGLTLTPAQQQLLLQQAQAQAQLLAAAVQQHSASQQHSAAGATISASAATPMTQIPLSQPIQIAQDLQQLQQLQQQNLNLQQFVLVHPTTNLQPAQFIISQTPQGQQGLLQAQNLLTQLPQQSQANLLQSQPSITLTSQPATPTRTIAATPIQTLPQSQSTPKRIDTPSLEEPSDLEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAENLSSDSSLSSPSALNSPGIEGLSRRRKKRTSIETNIRVALEKSFLENQKPTSEEITMIADQLNMEKEVIRVWFCNRRQKEKRINPPSSGGTSSSPIKAIFPSPTSLVATTPSLVTSSAATTLTVSPVLPLTSAAVTNLSVTGTSDTTSNNTATVISTAPPASSAVTSPSLSPSPSASASTSEASSASETSTTQTTSTPLSSPLGTSQVMVTASGLQTAAAAALQGAAQLPANASLAAMAAAAGLNPSLMAPSQFAAGGALLSLNPGTLSGALSPALMSNSTLATIQALASGGSLPITSLDATGNLVFANAGGAPNIVTAPLFLNPQNLSLLTSNPVSLVSAAAASAGNSAPVASLHATSTSAESIQNSLFTVASASGAASTTTTASKAQ DIP protein P14859-1 original sequence version: 191 term_ade05 Preterminal protein Bellett protein Precursor terminal protein PTP protein protein ade05 Human adenovirus C serotype 5 (HAdV-5) HAdV-5 Human adenovirus 5 MALSVNDCARLTGQSVPTMEHFLPLRNIWNRVRDFPRASTTAAGITWMSRYIYGYHRLMLEDLAPGAPATLRWPLYRQPPPHFLVGYQYLVRTCNDYVFDSRAYSRLRYTELSQPGHQTVNWSVMANCTYTINTGAYHRFVDMDDFQSTLTQVQQAILAERVVADLALLQPMRGFGVTRMGGRGRHLRPNSAAAAAIDARDAGQEEGEEEVPVERLMQDYYKDLRRCQNEAWGMADRLRIQQAGPKDMVLLSTIRRLKTAYFNYIISSTSARNNPDRRPLPPATVLSLPCDCDWLDAFLERFSDPVDADSLRSLGGGVPTQQLLRCIVSAVSLPHGSPPPTHNRDMTGGVFQLRPRENGRAVTETMRRRRGEMIERFVDRLPVRRRRRRVPPPPPPPEEEEGEALMEEEIEEEEEAPVAFEREVRDTVAELIRLLEEELTVSARNSQFFNFAVDFYEAMERLEALGDINESTLRRWVMYFFVAEHTATTLNYLFQRLRNYAVFARHVELNLAQVVMRARDAEGGVVYSRVWNEGGLNAFSQLMARISNDLAATVERAGRGDLQEEEIEQFMAEIAYQDNSGDVQEILRQAAVNDTEIDSVELSFRLKLTGPVVFTQRRQIQEINRRVVAFASNLRAQHQLLPARGADVPLPPLPAGPEPPLPPGARPRHRF DIP protein P04499 original sequence version: 58 pou2f1-ptp-1 1 3 unspecified role unspecified role prey prey Region 1-183 Region 1-183 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecolx Escherichia coli 2 unspecified role unspecified role bait bait Region 280-439 Region 280-439 sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain GST-tag GST-tag gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P14859-1:p.Arg380Trp R380W mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R W This feature has been corrected as a result of our quality control procedures. The original label was 'R380W'. Wed May 02 15:43:29 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg380trp' Tue Jun 30 16:52:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg380Trp' P14859-1:p.Lys382Thr K382T mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K T This feature has been corrected as a result of our quality control procedures. The original label was 'K382T'. Wed May 02 16:57:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys382thr' Tue Jun 30 20:06:02 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys382Thr' P14859-1:p.Arg383Ser R383S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R S This feature has been corrected as a result of our quality control procedures. The original label was 'R383S'. Wed May 02 16:57:10 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg383ser' Tue Jun 30 17:01:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg383Ser' P14859-1:p.Thr384Pro T384P mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain T P This feature has been corrected as a result of our quality control procedures. The original label was 'T384P'. Wed May 02 17:01:56 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr384pro' Tue Jun 30 19:53:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr384Pro' P14859-1:p.Thr384Ser T384S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain T S This feature has been corrected as a result of our quality control procedures. The original label was 'T384S'. Wed May 02 19:14:11 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr384ser' Tue Jun 30 18:31:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr384Ser' P14859-1:p.Lys403Glu K403E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K E This feature has been corrected as a result of our quality control procedures. The original label was 'K403E'. Wed May 02 17:54:07 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys403glu' Tue Jun 30 17:40:40 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys403Glu' P14859-1:p.Lys403Met K403M mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K M This feature has been corrected as a result of our quality control procedures. The original label was 'K403M'. Wed May 02 18:28:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys403met' Tue Jun 30 17:21:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Lys403Met' P14859-1:p.Glu408Gly E408G mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain E G This feature has been corrected as a result of our quality control procedures. The original label was 'E408G'. Wed May 02 18:12:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu408gly' Tue Jun 30 17:48:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu408Gly' P14859-1:p.Thr410Ser T410S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain T S This feature has been corrected as a result of our quality control procedures. The original label was 'T410S'. Wed May 02 18:54:54 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr410ser' Tue Jun 30 17:32:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr410Ser' P14859-1:p.Val425Gly V425G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain V G This feature has been corrected as a result of our quality control procedures. The original label was 'V425G'. Wed May 02 16:21:16 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'val425gly' Tue Jun 30 18:20:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Val425Gly' P14859-1:p.Phe427Tyr F427Y mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain F Y This feature has been corrected as a result of our quality control procedures. The original label was 'F427Y'. Wed May 02 16:23:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe427tyr' Tue Jun 30 17:43:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe427Tyr' P14859-1:p.Cys428Tyr C428Y mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C Y This feature has been corrected as a result of our quality control procedures. The original label was 'C428Y'. Wed May 02 15:05:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'cys428tyr' Tue Jun 30 17:28:12 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Cys428Tyr' P14859-1:p.Asn429Asp N429D mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain N D This feature has been corrected as a result of our quality control procedures. The original label was 'N429D'. Wed May 02 16:43:09 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asn429asp' Tue Jun 30 17:28:11 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Asn429Asp' P14859-1:p.Arg431Ser R431S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain R S This feature has been corrected as a result of our quality control procedures. The original label was 'R431S'. Wed May 02 15:27:37 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg431ser' Tue Jun 30 15:46:13 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Arg431Ser' P14859-1:p.[Ile373Thr;Val425Ala] I373T/V425A mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain V A certain certain sequence position certain certain certain sequence position certain I T This feature has been corrected as a result of our quality control procedures. The original label was 'I373T/V425A'. Wed May 02 19:12:15 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile373thr,val425ala' Tue Jun 30 15:51:43 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile373Thr;Val425Ala]' P14859-1:p.[Ser377Gly;Lys420Glu] S377G/K420E mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain S G certain certain sequence position certain certain certain sequence position certain K E This feature has been corrected as a result of our quality control procedures. The original label was 'S377G/K420E'. Wed May 02 15:05:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser377gly,lys420glu' Tue Jun 30 18:27:10 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser377Gly;Lys420Glu]' P14859-1:p.[Lys382Glu;Leu394Ser] K383E/L394S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain L S certain certain sequence position certain certain certain sequence position certain K E Wed May 02 16:30:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys382glu,leu394ser' Tue Jun 30 17:13:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys382Glu;Leu394Ser]' P14859-1:p.[Glu400Gly;Met418Leu] E400G/M418L mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain E G certain certain sequence position certain certain certain sequence position certain M L This feature has been corrected as a result of our quality control procedures. The original label was 'E400G/M418L'. Wed May 02 15:45:35 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu400gly,met418leu' Tue Jun 30 17:29:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Glu400Gly;Met418Leu]' P14859-1:p.[Lys403Gln;Arg424Ser] K403Q/R424S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K Q certain certain sequence position certain certain certain sequence position certain R S This feature has been corrected as a result of our quality control procedures. The original label was 'K403Q/R424S'. Wed May 02 14:43:00 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'lys403gln,arg424ser' Tue Jun 30 19:40:48 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Lys403Gln;Arg424Ser]' P14859-1:p.[Ile412Phe;Val425Asp] I412F/V425D mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain I F certain certain sequence position certain certain certain sequence position certain V D This feature has been corrected as a result of our quality control procedures. The original label was 'I412F/V425D'. Wed May 02 19:43:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile412phe,val425asp' Tue Jun 30 16:23:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ile412Phe;Val425Asp]' P14859-1:p.[Asp414Gly;Val425Gly] D414G/V425G mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain D G certain certain sequence position certain certain certain sequence position certain V G This feature has been corrected as a result of our quality control procedures. The original label was 'D414G/V425G'. Wed May 02 18:49:46 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp414gly,val425gly' Tue Jun 30 16:34:49 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asp414Gly;Val425Gly]' P14859-1:p.[Gln415Leu;Cys428Ser] Q415L/C428S mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain C S certain certain sequence position certain certain certain sequence position certain Q L This feature has been corrected as a result of our quality control procedures. The original label was 'Q415L/C428S'. Wed May 02 15:50:20 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln415leu,cys428ser' Tue Jun 30 16:43:33 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Gln415Leu;Cys428Ser]' P14859-1:p.[Glu419Gly;Lys433Glu] E419G/K433E mutation decreasing strength mutation decreasing interaction strength mutation decreasing strength substitut analysis substitution analysis substitut analysis certain certain sequence position certain certain certain sequence position certain K E certain certain sequence position certain certain certain sequence position certain E G This feature has been corrected as a result of our quality control procedures. The original label was 'E419G/K433E'. Wed May 02 14:51:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu419gly,lys433glu' Tue Jun 30 19:57:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Glu419Gly;Lys433Glu]' ecolx Escherichia coli direct interaction direct interaction