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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
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      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
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        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Structural basis for a novel interaction between TXNIP and Vav2.</fullName>
        </names>
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          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="26919541" refType="primary-reference" refTypeAc="MI:0358"/>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Structural basis for a novel interaction between TXNIP and Vav2.</attribute>
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            <attribute name="publication year" nameAc="MI:0886">2016</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Liu S., Wu X., Zong M., Tempel W., Loppnau P., Liu Y.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">yanliliu@mail.ccnu.edu.cn</attribute>
            <attribute name="author-announcement">22-Jun-2016: Contacted by IntAct-Help.</attribute>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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          <attribute name="author-list" nameAc="MI:0636">Liu S., Wu X., Zong M., Tempel W., Loppnau P., Liu Y.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">yanliliu@mail.ccnu.edu.cn</attribute>
          <attribute name="accepted">Accepted 2016-MAY-18 AT 09:47 BST AT 09:47 BST by MARTA</attribute>
          <attribute name="journal" nameAc="MI:0885">FEBS letters</attribute>
          <attribute name="publication year" nameAc="MI:0886">2016</attribute>
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      </experimentDescription>
      <experimentDescription id="2">
        <names>
          <fullName>Structural basis for a novel interaction between TXNIP and Vav2.</fullName>
        </names>
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            <attribute name="author-announcement">22-Jun-2016: Contacted by IntAct-Help.</attribute>
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              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
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        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>itc</shortLabel>
            <fullName>isothermal titration calorimetry</fullName>
            <alias type="go synonym" typeAc="MI:0303">ITC</alias>
            <alias type="synonym" typeAc="MI:1041">ITC</alias>
            <alias type="synonym" typeAc="MI:1041">itc</alias>
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            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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          <attribute name="author-list" nameAc="MI:0636">Liu S., Wu X., Zong M., Tempel W., Loppnau P., Liu Y.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">yanliliu@mail.ccnu.edu.cn</attribute>
          <attribute name="accepted">Accepted 2016-MAY-18 AT 09:47 BST AT 09:47 BST by MARTA</attribute>
          <attribute name="journal" nameAc="MI:0885">FEBS letters</attribute>
          <attribute name="publication year" nameAc="MI:0886">2016</attribute>
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          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="3">
        <names>
          <shortLabel>txnip_human</shortLabel>
          <fullName>Thioredoxin-interacting protein</fullName>
          <alias type="gene name" typeAc="MI:0301">TXNIP</alias>
          <alias type="gene name synonym" typeAc="MI:0302">VDUP1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Vitamin D3 up-regulated protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Thioredoxin-binding protein 2</alias>
        </names>
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          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E3D3" version="SP_100" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_006463.3"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014752" version="SP_160"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014756" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GEI" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GEJ" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4GFX" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LL1" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LL4" version="SP_160"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROF" version="SP_160"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5CQ2" version="SP_160"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5DZD" version="SP_160"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071228" version="SP_160"/>
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        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
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        </organism>
        <sequence>MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTSEYLRYEDTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGKYGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDEISIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVEYSLLIYVSVPGSKKVILDLPLVIGSRSGLSSRTSSMASRTSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPLLDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNVQ</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q9H3M7 original sequence version: null</attribute>
          <attribute name="crc64">B0FE2D35D0B0735A</attribute>
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      </interactor>
      <interactor id="4">
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          <shortLabel>vav2_human</shortLabel>
          <fullName>Guanine nucleotide exchange factor VAV2</fullName>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR037832" version="SP_209"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P52735" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2DLZ" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2DM1" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LNW" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2LNX" version="SP_209"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROJ" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-114604" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-193648" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2029482" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2424491" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2871796" version="SP_209"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051056" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000219" version="SP_209"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000980" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2871809" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3928665" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-416482" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-445144" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5218920" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8980692" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013026" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013106" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013148" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013149" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013404" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013408" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013423" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9664422" version="SP_209"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-4420097" version="SP_209"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_001127870.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003362.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_005272270.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-33088N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERSASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P52735 original sequence version: 114</attribute>
          <attribute name="crc64">C186911605FD5B73</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>src_human</shortLabel>
          <fullName>Proto-oncogene tyrosine-protein kinase Src</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">pp60c-src</alias>
          <alias type="gene name" typeAc="MI:0301">SRC</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SRC1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Proto-oncogene c-Src</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P12931" version="SP_111" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-28966850" refType="intact-secondary"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000350941" version="SP_256" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000362668" version="SP_256" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000362680" version="SP_256" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q86VB9" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q9H5A8" version="SP_111" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383910" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q76P87" version="SP_133" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="E1P5V4" version="SP_147" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-621482" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000358208" version="SP_256" refType="transcript"/>
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          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000373578" version="SP_256" refType="transcript"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000641" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2000811" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001237" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001243" version="SP_256"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:2001286" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000980" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001245" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001452" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008266" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017441" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020635" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036028" version="SP_256"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036860" version="SP_256"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P12931" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A07" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A08" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A09" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1A" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1B" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1C" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1A1E" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1FMK" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1HCS" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1HCT" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1KSW" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O41" version="SP_256"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O44" version="SP_256"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4H" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4I" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4J" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4K" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4L" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4M" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4N" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4O" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4P" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4Q" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O4R" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1O48" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1Y57" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YI6" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YOJ" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YOL" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1YOM" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BDF" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2BDJ" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2H8H" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2SRC" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3VRO" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZMP" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3ZMQ" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4F59" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4F5A" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4F5B" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4HXJ" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4K11" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MXO" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MXX" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MXY" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MXZ" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6ATE" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6C4S" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6E6E" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6EHJ" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1227986" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1251985" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1253288" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1257604" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1295596" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1433557" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1433559" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-171007" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-177929" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-180292" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-186763" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-191650" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2029481" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-210990" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2219530" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2682334" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-354192" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-354194" version="SP_256"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1SHD" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-372708" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-375165" version="SP_256"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-391160" version="SP_256"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3928663" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3928664" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-3928665" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418555" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418592" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418594" version="SP_256"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-418886" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-428542" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-430116" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-437239" version="SP_256"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8874081" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8876493" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8934593" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8934903" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8940973" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8941858" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9009391" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9032500" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9603381" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9620244" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9649948" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9656223" version="SP_256"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9664323" version="SP_256"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_005408.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_938033.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_011527315.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883513.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883514.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883515.1"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="XP_016883516.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-1059N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGPSAAFAPAAAEPKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 188</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 189</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 190</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 191</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 115</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 116</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 164</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 142</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 143</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 150</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 160</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 184</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 155</attribute>
          <attribute name="remark-internal">DIP protein P12931-1 original sequence version: 155</attribute>
          <attribute name="remark-internal">DIP protein P12931 original sequence version: 202</attribute>
          <attribute name="crc64">C1908084683E5DE8</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-25084-1">
        <names>
          <shortLabel>txnip-vav2-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686229" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4ROJ"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-25084-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="8">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686233" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000980"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="667"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="782"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="9">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="10">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686235" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="327"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="338"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">t1 f2</attribute>
        </attributeList>
      </interaction>
      <interaction id="11" imexId="IM-25084-2">
        <names>
          <shortLabel>txnip-vav2-2</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686246" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-25084-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="12">
            <xref>
              <primaryRef db="interpro" dbAc="MI:0449" id="IPR000980"/>
            </xref>
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="13">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686252" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="667"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="782"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="14">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="15">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686249" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="327"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="338"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <parameterList>
          <parameter term="kd" termAc="MI:0646" unit="molar" unitAc="MI:0648" base="10" exponent="-6" factor="14"/>
        </parameterList>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">f1c</attribute>
        </attributeList>
      </interaction>
      <interaction id="16" imexId="IM-25084-3">
        <names>
          <shortLabel>src-txnip-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686298" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-25084-3" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>2</experimentRef>
        </experimentList>
        <participantList>
          <participant id="17">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="18">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686305" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000980"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="145"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="250"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
          <participant id="19">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="20">
                <names>
                  <shortLabel>binding range</shortLabel>
                  <fullName>binding range</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-11686302" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>binding region</shortLabel>
                    <fullName>binding-associated region</fullName>
                    <alias type="synonym" typeAc="MI:1041">binding region</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0117" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456493" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <begin position="327"/>
                    <endStatus>
                      <names>
                        <shortLabel>certain</shortLabel>
                        <fullName>certain sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">certain</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0335" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-540564" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                    <end position="338"/>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <parameterList>
          <parameter term="kd" termAc="MI:0646" unit="molar" unitAc="MI:0648" base="10" exponent="-6" factor="12"/>
        </parameterList>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">f1B</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>