UniProt UniProt http://www.uniprot.org Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Molecular vision 2009 imex curation Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu 04-Aug-2016: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro pull down pull down weight autoradiogra molecular weight estimation by autoradiography weight autoradiogra Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Accepted 2016-JUL-11 AT 09:27 BST AT 09:27 BST by ORCHARD Molecular vision 2009 imex curation you are right. thanks. did not read to the end... Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Molecular vision 2009 imex curation Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu 04-Aug-2016: Contacted by IntAct-Help. Only protein-protein interactions mouse-retina Mus musculus retina retina retinal tissue anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Accepted 2016-JUL-11 AT 09:27 BST AT 09:27 BST by ORCHARD Molecular vision 2009 imex curation you are right. thanks. did not read to the end... Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Interaction of ciliary disease protein retinitis pigmentosa GTPase regulator with nephronophthisis-associated proteins in mammalian retinas. Molecular vision 2009 imex curation Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu 04-Aug-2016: Contacted by IntAct-Help. Only protein-protein interactions bovin-retina Bovine retina retina retinal tissue anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Murga-Zamalloa CA., Desai NJ., Hildebrandt F., Khanna H. Origin of in vitro-translated NPHP4 and NPHP1 according seq length in fig 1C. Origin of GST-RPGR according ref. 19 (PMID 16043481) Hemant.Khanna@umassmed.edu Accepted 2016-JUL-11 AT 09:27 BST AT 09:27 BST by ORCHARD Molecular vision 2009 imex curation you are right. thanks. did not read to the end... nphp4_mouse Nephrocystin-4 Nphp4 Nephroretinin protein protein mouse Mus musculus Mouse MGDWHRAFTQNTLVPPHPQRARQLGKESTAFQCILKWLDGPLIKQGILDMLSELECHLRVTLFDVTYKHFFGRTWKTTVKPTNQPSKQPPRITFNEPLYFHTTLSHPSIVAVVEVVTEGRKRDGTLQLLSCGFGILRIFGNKPESPTSAAQDKRLRLYHGTPRALLHPLLQDPIEQNKFMRLMENCSLQYTLKPHPPLEPAFHLLPENLLVSGFQQIPGLLPPHGDTGDALRKPRFQKPTTWHLDDLFFTLYPSLEKFEEELVQLLISDREGVGLLDSGTLEVLERRLHVCVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKISASSKNSSGNQALVLRSHLRLPEMVSHPAFAIVFQLEYVFNSPSGADGGASSPTSISSVACMHMVRWAVWNPDLEVGPGKVTLPLQGGVQQNPSRCLVYKVPSASMSSEEVKQVESGTIQFQFSLSSDGPTEHANGPRVGRRSSRKMPASPSGTPAPAARDLAATQDSPVGPGLSLSQLTASPLSPALQSSSKPPLQPPDSSQSPEGPQLQAESVLESRVSHLEADLSQPASLQGTPAVEHLQELPFTPLHAPIVVGAQTRSSRSQLSRAAMVLLQSSGFPEILDASQQPVEAVNPIDPVRFNPQKEESDCLRGNEIVLQFLAFSRAAQDCPGTPWPQTVYFTFQFYRFPPETTPRLQLVKLDGTGKSGSGSLSHILVPINKDGSFDAGSPGLQLRYMVDPGFLKPGEQRWFAHYLAAQTLQVDVWDGDSLLLIGSAGVQMKHLLRQGRPAVQVSHELEVVATEYEQEMMAVSGDVAGFGSVKPIGVHTVVKGRLHLTLANVGHACEPRARGSNLLPPSRSRVISNDGASFFSGGSLLIPGGPKRKRVVQAQRLADVDSELAAMLLTHTRAGQGPQAAGQEADAVHKRKLERMRLVRLQEAGGDSDSRRISLLAQHSVRAQHSRDLQVIDAYRERTKAESIAGVLSQAITTHHTLYATLGTAEFFEFALKNPHNTQHTVAIEIDSPELSIILDSQEWRYFKEATGLHTPLEEDMFHLRGSLAPQLYLRPRETAHIPLKFQSFSVGPLAPTQAPAEVITEKDAESGPLWKCSAMPTKHAKVLFRVETGQLIAVLCLTVEPQPHVVDQVFRFYHPELTFLKKAIRLPPWHTLPGAPVGMPGEDPPVHVRCSDPNVICEAQNVGPGEPRDVFLKVASGPSPEIKDFFVVIYADRWLAVPVQTWQVCLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAFTSHPQELKTDPAGVFVLPPHGVQDLHVGVRPRRAGSRFVHLNLVDIDYHQLVASWLVCLSCRQPLISKAFEITMAAGDEKGTNKRITYTNPYPSRRTYRLHSDRPELLRFKEDSFQVAGGETYTIGLRFLPSGSAGQEEILIYINDHEDKNEETFCVKVLYQ DDB9739850AEA5C4 ce290_bovin Centrosomal protein of 290 kDa CEP290 NPHP6 Nephrocystin-6 protein protein bovin Bos taurus (Bovine) Bovine ERQLRKENGKQKNELMAMEAEVGEKIGRLQRFKEMAVFKIAALQKVVDNSVSLSELELANRQYNELTAKYRDILQKDNMLVQRTNNLEHLECENVSLKEQMESINKELEITKEKLHTIEQAWEQETKLGNESNMDKAKKSVTNSEIVSISKKITMLEMKELNERQRAEHSQKMYEHVKTSLQQVEERNFELETKFAELTRINLEAQKVEQMLRDELADSVSKTVSDADRQHILELEKSEMELKVEVSKLKEISDIAKRQVEILNAQQQSREKEVESLRTQLLDYQAQSDEKALIAKLHQHVVSLQASEAAALGKVESVASKLQKVEAHTLRLEQKLDEKEQALFYARLEGRNRAKHLRQTIQSLRRQFSGALPLAQQEKFSKTMIQLQNDKLKIMEEMKNSQQEHRSLKNKTLEMELKLKGLEDLISTLKDARGAQKVISWHTKIEELRLQELKLNRELVKDKEEIKYLNNIISEYENTISSLEEEIVQQNKFHEERQMAWDQREVELERQLDVFDRQQSEILREAQKFEEATGSMPDPSLPIPNQLEIALRKIKENIRIILETQATCRSLEEKLREKESALRLAEENILSRDKVINELRLRLPATAEQEKLLAEFSRKEVEPKSHHTLKLAHQTIANMQARLNQKEEVLKKYQHLLEKAREEQREIVKKHEEELHTLHRKLELQADNSLSKFKETAWDLIKQSPTPVPTNKHFIRLAEMEQTVAEQDDSLSSLVIKLKQVSQDLERQKEITELKIKEFENMKLRLQENHADEVKKIKAEVEDLRCLLVQSQKESQSLKSELQTQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEMTAAAEERIISMTSQKEANLNVQQIVDRHTKELKSQIEDLNENILKLKEALKTSKNRENTLTDNLNDLTNELQNKQKAYGKVLREKDAVDQENNELKRQIKRLTSGLQGKPLIDNKQSLIEELQKKIKKLESQLERKVDEAEMKPMKEKSAREEVIRWEEGKKWQTKIEGIRNKLKEKEGEVYILTKQLTTLKDLFAKADKEKLTLQRKLKTTGLTVDQVMAARVLESEKELEELKKRNLDLENDISYMRSHQALPRDSVIEDLHLQNKYLQEKLHALEKQLSKDAYSRPSTSGIDSDDHYQREQELQRENLKLSSENIELKFQLEQANKDLPRLKNQVRDLKEMCEFLKKEKAEVERKLGRVRGSGRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEMENEKLKAELEKLKVHLGRQLSMHYESKAKGTEKIVAENERLRKELKKIEILKHVPEGDETEQGLQRELRVLRLANSQLEKEKEELIHRIEISKDQNGPDSTISDPDHLMEKIKDLETQLRTSDMEKQHLKEEIQKLKKELENFDPSFFEEIEDLKYNYKEEVKKNILLEEKLKKLSEQFGVELTSPVAASEQFEDEQENPVNFPIY 18A31723723A873E e1bjb4_bovin RPGRIP1L protein protein bovin Bos taurus (Bovine) Bovine MSGPTDETAGDLPVKDIGLNLFGMGGLQETSTTRTMKSRQAVSRISREELEDRFLRLHDENILLKQHARKQEDKIKRMATKLIRLVNDKKRYEQVGGGPKRLGRDVEMEEMIERLQEKVHELERQNEVLKSRLISTKQQLQIQGHRHTPYSYVQSRVNTGRRRVNENAGLQECPRKGIKFQDTDVAETVQTMPTKYSNSLLKEARGEIRNLENVIESQRGQIEELERLAEILKTQLRRKENEIELSLLQLREHQATDQRSNIRDNVELIKLHKQLVEKSNALSVMEGKFIQLQEKQKTLRISHDALMANGDELNLQLKEQRLKCCSLEKQLRSMTFSERRIEELQDRISDLEKERELLKENYDKLYNSAFSAAHEEQWKLKEQQLKIQIAQLETALKSDLTDKTEILDRLKTERDQNEKISQENRQLQLQYLEQKQQLDELKNRMKFYNQESDINADELSEALLLIKAQKSQKNGDLSFLEKVDSKINKDLERSMKELQATHAETVQELEKTRNMLIMQHKINKDYQMEVEAVTQKMENLQQDYELKVEQYVHLLDIRAARIQKLEAQLKDIAYGTKQYKFKPEIMPDDSVDEFDETIHLERGENLFEIHINKVTFSSEVLQASGDKEPVTFCTYAFYDFELQTTPIVRGLHPEYNFTSQYLVHVNDLFLQYIQKNTVTLEVHQAYSTDYETIAACQLRFHEILEKSGRIFCTASLVGTKGDISNFGTVEYWFRLRVPMDQAIRLYRERAKALGYITSNFKGPEQMQWLSHQAPKTAQLSSTDSTDGNLNELHITIRCCNHLQSRASHLQPHPYVVYKFFDFADHDTAIIPSSNDPQFDDHMCFPVPMNMDLDRYLKSESLSFYVFDDSDTQENIYIGKVSVPLISLAHDRCISGIFELTDHEKHPAGTIHVILKWKFAYLPPSGCITTEDLGNFRHKEESEVVQRLLPTSSFSTIIAAPTPKPRRLTTKDKKVSFMDITPHQHYKETSTLPEDRKEISPEVEHIPEREIDMPTVSHIPKVPQESSVDKVKENTEKTQQGKDDDVSLLSEGQLAERSLTSSEDETEITEELEPEDEGDRSASDSDECIIPGPVSKNIKQPPEKIRIEIIALSLNDSRVTADDTIQRLFVECRFYSLPAEETPVSLPKPKSGQWVYYNYSYVIYMDKENNQAKRDILKAILLKQEMPNRSVRFTVVSDPPEDEQDLECEDIGIANVDLADVFREGRDIIEQNIDVLDARASGGGIGKLRVTVEALHALRSVYEQFRDDLEA 1F35805778A47281 nphp4_human Nephrocystin-4 NPHP4 KIAA0673 Nephroretinin protein protein human Homo sapiens Human MNDWHRIFTQNVLVPPHPQRARQPWKESTAFQCVLKWLDGPVIRQGVLEVLSEVECHLRVSFFDVTYRHFFGRTWKTTVKPTKRPPSRIVFNEPLYFHTSLNHPHIVAVVEVVAEGKKRDGSLQTLSCGFGILRIFSNQPDSPISASQDKRLRLYHGTPRALLHPLLQDPAEQNRHMTLIENCSLQYTLKPHPALEPAFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPITGHLDDLFFTLYPSLEKFEEELLELHVQDHFQEGCGPLDGGALEILERRLRVGVHNGLGFVQRPQVVVLVPEMDVALTRSASFSRKVVSSSKTSSGSQALVLRSRLRLPEMVGHPAFAVIFQLEYVFSSPAGVDGNAASVTSLSNLACMHMVRWAVWNPLLEADSGRVTLPLQGGIQPNPSHCLVYKVPSASMSSEEVKQVESGTLRFQFSLGSEEHLDAPTEPVSGPKVERRPSRKPPTSPSSPPAPVPRVLAAPQNSPVGPGLSISQLAASPRSPTQHCLARPTSQLPHGSQASPAQAQEFPLEAGISHLEADLSQTSLVLETSIAEQLQELPFTPLHAPIVVGTQTRSSAGQPSRASMVLLQSSGFPEILDANKQPAEAVSATEPVTFNPQKEESDCLQSNEMVLQFLAFSRVAQDCRGTSWPKTVYFTFQFYRFPPATTPRLQLVQLDEAGQPSSGALTHILVPVSRDGTFDAGSPGFQLRYMVGPGFLKPGERRCFARYLAVQTLQIDVWDGDSLLLIGSAAVQMKHLLRQGRPAVQASHELEVVATEYEQDNMVVSGDMLGFGRVKPIGVHSVVKGRLHLTLANVGHPCEQKVRGCSTLPPSRSRVISNDGASRFSGGSLLTTGSSRRKHVVQAQKLADVDSELAAMLLTHARQGKGPQDVSRESDATRRRKLERMRSVRLQEAGGDLGRRGTSVLAQQSVRTQHLRDLQVIAAYRERTKAESIASLLSLAITTEHTLHATLGVAEFFEFVLKNPHNTQHTVTVEIDNPELSVIVDSQEWRDFKGAAGLHTPVEEDMFHLRGSLAPQLYLRPHETAHVPFKFQSFSAGQLAMVQASPGLSNEKGMDAVSPWKSSAVPTKHAKVLFRASGGKPIAVLCLTVELQPHVVDQVFRFYHPELSFLKKAIRLPPWHTFPGAPVGMLGEDPPVHVRCSDPNVICETQNVGPGEPRDIFLKVASGPSPEIKDFFVIIYSDRWLATPTQTWQVYLHSLQRVDVSCVAGQLTRLSLVLRGTQTVRKVRAFTSHPQELKTDPKGVFVLPPRGVQDLHVGVRPLRAGSRFVHLNLVDVDCHQLVASWLVCLCCRQPLISKAFEIMLAAGEGKGVNKRITYTNPYPSRRTFHLHSDHPELLRFREDSFQVGGGETYTIGLQFAPSQRVGEEEILIYINDHEDKNEEAFCVKVIYQ 8C974278F4EE4505 q29rs3_bovin IQCB1 protein protein bovin Bos taurus (Bovine) Bovine MKPTGTDPRILSLAAEVAKSPEQNVPVILLKLKEIINNTPLGSSELKKIKQDIYCYDLIQYCLLVLSQDCSRIQGGWTTVSQLTQILSHCCVGLEPGEDAEEFYNELLPSAAENFLVLGRRLQTCFINAAKGEEKDALLHFFEVVTDSLFWLLGGHVQLIQNVLKSDHFLRLLQTDSVQIGSMVMTLLQNILQINSGDLLRIEGKILHSILDEVVFKLLSTPSPVIRGTATKLLLLMAESHQEILILLRLSACYKGLRSLLNKQEPGTEFSQELRQLIGLLSPKACQEVKDQKQHKAACLIQAYWKGFQTRKRLKKLPSAVITLQRSFRSKRTKMLMKLSRQKEEEDHRLQLQIQRQRAMRLSREIRLNMLEIVHPGQVEKHNREIEEKSALIIQKHWKGYRERKNFRQQRPSLTEYKAAVILQRATLKFLAKCRKKKKLFAPWPGLRELTDARRIELKQQVDDYIRRHPGSQISDVTSRELHSQAQERLQCYFMGRALEERSQQHREALMAQISTNIEQLMKAPSLKEAEGKDPELFLSRSRPVAAKAKQAHLTTLKHIQAPWWKKLGEEAGDDIDIPKDELSVELGTLFIGGTKPP 8B21F6FE56D4AC98 q9gmd3_bovin RPGR protein protein bovin Bos taurus (Bovine) Bovine KQEIIEKPKQHTTYTESDDSNEYENEEISPKVTEGRVYKQLLAQGMYAMPVAISMETFSDEDVGDDSDQQSPQTSTSAEGLQKGTFRHENKHDVYPLNTEEIEKESDEGQSQKDSEANEIVSEMESDLVKMTDLKDIRKTEENRKNTDTFFDDLPNRYMNIEDEEDKDFVKESKGDKQDMIFDSEQASIEEENSYLEGESESQQSIADGFQQSESIEFNSVEKDDDEVETNQNLWYSRTFIKQRHEEARHRLSRIMAKYEFKCDRLSRIPEEQEEDSEGSGVEEQEIEANEEECGEKEKEETALLSDDLTDRAEVSEGKGKLGGEAEHVPKGGGEGIRKEGNSGVEQRSRTGSEEGEEGEDMGEGVIESLGKGEKDLEEEEQEQKEREQGHQEERSTGRKEAGEREQGGGEGEEEADEEEGEEEKDKEKEEGKEKEEEEEQEGEGEELEEGRWQDGEEGEGKGDEEGQEGGREEEGDREGQEGEEEGEGEEAGEGEEEGEGEEEGEGEEEGEGEEAGEGEEAGEGKGREEEEKGEEGEGEEKVGGEEEEDGEGQEGEEEEEEEGDGEEEEEGDGEEQEAEGGEVEGDGEVEEVGDEEKEGDGEEEGDGEREGGTGEGDEEEQKGEEEEEGDGEGEEEGDGEGEEEGDGEGEEEGDGEEQEGEKEEDGEGEEEGDGEGEEGDGEGEEEGDGEGEEEGDGEGEEEGDGEEQEGEEEEDGEGEEEGDGEQEGEEEEEGGGDEGEEEGEGEEELEEGEGEEEGEAEGEEGEGEEEEGEGEKGGEGLGGEGEEGEEEGGERVEEGEGEREREGMEREEKEWVVRKRKEKENGRGEEKEEDENNEEEKGKCQETGNEESGRQGRKGGGRESKVSKIRGSGKYGKDRTHPKKFTTNREGKGKGHGVQRFKIPVQSKQLLVNGPPGSKKFWNNVLPHYLELK 0D7EFD55E5302650 a0jn59_bovin INVS protein protein bovin Bos taurus (Bovine) Bovine MNRSENLFFAGSSLASQVHAAAINGDKGALHKLIIGNSALKDKEDQFGRTPLMYCVLADRLDCADTLLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHKSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRREAEQQKGRLSPDSCRPHAPLCLPRTQAEPHRQSRAPSKQPPCSDKAQGPERKACRRSPGRGSPSRAPQKEQQLSSDLQRTEPRKPNETAREHSKGRSACVHFSPSEGSDGNRRPGVCPAEKPRGETAGEQHCDKGKGSSKQPSHVKGAGPDAEGEEPSWAATSLPQQDSHWKASRRQDAAPKAMRASQKRRSQELRGGRRSPAGSSRPGSAKGEVVHPGQSPLHHRTPRNTVTQDKLAGGTSSDLPPSTEVLRSGVRKLGTSARSEDTRLPKETDPAPGPLPGQTVNIDLLPVELRLQIIQRERSRKELFRRKNKAAAIIQRAWRSYQLRKHLSHLLHVKQLGARDMDRWNRECLALILQVWRKELELKPPKTMAVSKTTKSPPKGSSGTKPTRHSVLKQIYGSQEGKVRQPTRSSKAHSVLGLNSVSNLQCIHLLKNSGKSQNFSYNLQSANPSRNKLKLRLPKEEDCARGARIASADFKFSD 6D44179C9CEA526B rpgr_human X-linked retinitis pigmentosa GTPase regulator RPGR RP3 XLRP3 protein protein human Homo sapiens Human MREPEELMPDSGAVFTFGKSKFAENNPGKFWFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLPYSSLTSGNVLQRTLSARMRRRERERSPDSFSMRRTLPPIEGTLGLSACFLPNSVFPRCSERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPATTIEAFSDEEVGNDTGQVGPQADTDGEGLQKEVYRHENNNGVDQLDAKEIEKESDGGHSQKESEAEEIDSEKETKLAEIAGMKDLREREKSTKKMSPFFGNLPDRGMNTESEENKDFVKKRESCKQDVIFDSERESVEKPDSYMEGASESQQGIADGFQQPEAIEFSSGEKEDDEVETDQNIRYGRKLIEQGNEKETKPIISKSMAKYDFKCDRLSEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEDHEFSKTEELKLEDVDEEINAENVESKKKTVGDDESVPTGYHSKTEGAERTNDDSSAETIEKKEKANLEERAICEYNENPKGYMLDDADSSSLEILENSETTPSKDMKKTKKIFLFKRVPSINQKIVKNNNEPLPEIKSIGDQIILKSDNKDADQNHMSQNHQNIPPTNTERRSKSCTIL EAB16275A9A436C3 rpgr_mouse X-linked retinitis pigmentosa GTPase regulator Rpgr protein protein mouse Mus musculus Mouse MAESESLVPDTGAVFTFGKTKFAENIPSKFWFKNDIPICLSCGDEHTAIVTGNNKLYMFGSNNWGQLGLGSKAAIIKPTCIKALKPEKVKLAACGRNHTLVSTDTGGVYAAGGNNEGQLGLGDTDDRDTFHQIVFFTPADTIKQLSAGANTSAALTEDGKLFMWGDNSEGQIGLEDKSNVCIPHEVTVGKPISWISCGYYHSAFVTMDGELYTFGEPENGKLGLPNELLMNHRSPQRVLGIPERVIQVACGGGHTVVLTEKVVYAFGLGQFGQLGLGTFLFETSEPKIIERIKDQKICHISCGENHTALMTELGLLYTFGDGRHGKLGLGMENFTNQFFPTLCSNFLRFAVQLIACGGCHMLVFATPRLGTIDEPKFEDVYEPYISTGSFSINDLSPRSSLNRSLSARLRRRERERPPCSASMVGTLPPLEGTSASTSAYFYPSSPPFHLSVNNYPEKSPSESMEPLDSDYFEDKMNKDTETENSSAVDSENFGETNDILNMTHMMTTSSNEKLLDFSPIQKQQNQDTFEKVMESTPCTENEDSYEYEEMSKIKEVTVYKQYLAKGIYMIRPAEILEAFSDEEVGNGLDQVEEPRVFTDGKGLQSKQVGKESDEEIVSEKKTEVMEVADVKKIRESEENSKSDSLFDDLPDKTMNSESEDNKDIAEERRSSEQNMTFDSETELVEEPDSYMECERHSEQDSAEELEQPKLVEYSSEEKDEKDEKDDDEVETENLWYDRNCTEQETENVFRATRFFPKFDLKHDHLSGIPEEQEGPEDSEGNVVVEQVVQAQKENLEFEGDRKEAKAEAPSDVITEKEAPQLSETVKPEEGEMDEEISILNVEDTVEEERKEGEKEIVEEGSIPETEGSETIDITDEKLDEVLKEEDSASLLQRALREYNENPKGHMYDRVKSSSSEILGGNDPTSKDIKKAKKISFFNRMSLTGQKLMQNTNDPLPEIKPIGDQIALQSDKKDANQNHMGQNLQDSTTPNMEGKSKSCTIL DIP protein Q9R0X5 original sequence version: 68 021997395B74E6CA e1bjb5_bovin NPHP4 protein protein bovin Bos taurus (Bovine) Bovine MHDWHRIFDQNLLVPPHPQRARQPLKESTAFQCVLKWLDGPLIKQGVLELLSEVGCHLRVSLFDVTYRHFFGRTWRSSPRPAEPLTRQPARIVFNEPLYFHTSLNHPHIVAVVEVVVEGRRRDGTLQTLSCGFGILRIFSHKPESPTSTSQDKRLRLYHGSPRALLHPLLQDPIEQNKHMTLIENCSLQYTLRPHPLLEPVFHLLPENLLVSGLQQIPGLLPAHGESGDALRKPRLQKPLTCYLDDLFFTLYPSLEKFEEELLELVISDCFREAGSPLDVGTLEILERRLCVGVHNGLGFVQRPQVLVLVPELEVALTRSASFSRKVGSSSKASSGNQALVLRSRLRLPEMVRHPAFAIVFQLEYVFNSPSGADSNAASLSSLSSLACMHMVRWAVWNPSLEASSGQVMLPLQGGIQSNPSHCLVYKVPPASISSEEVKQVESGTVQFQYSLSPEEHPGTPTANASSPKAERRSFRKPPVSPSSPPASPSQGLTAAQDSPMGPGLSLSQLAASPPSPAPRRRSAKPSSQPPGSPVPSLVPGEFPLEGRISHLEADLSQTALALGTSAADHLQELPFTPVHAPIIAGTQTRSSGGKLSRASLALLQSAGFPEILDANKQPAEAVSPTDPVKFSPQKEESDCLQGNEIVLQFLAFSRVPQDEQAAPWPQTVYFTFQFYRFPPETTPRLQLVELADAGKTSSASLSHILAQIQKDGSFDAGSPGFQRKYLVDPGFLRPGEQRWFARYLAMQTLQIDVWDGDSLLLIGSAAVQLKHLLRQGRPAVQVSHELEVVATEYEQDAMVVSGDMTKFGCVRPIDVHTVVKGQLHLTLANVGHLCEQRVRSPSSLPPSRSRVISNDGVGNFMGGSLLTPGGPRLKNVVQAQKLADVDSELAALLFTQPRPGARGPQGINQEGDAVRRRKLERMRAVRLRECGLEPGRRGLGALAQQSLHAQHARDLQVIAAYRERTKAESIASALSTAITTQHTIHATLGAAEFFEFALRNPHNAQHMVTIEIDNPELSLILDGQEWRYFKDMADLHTPLEEDMFHLRGSLAPQLFLRPRETAHIPFKFQTFSVGPWASAQASAELRSEKDMDAGSPYKSSMMPTKHAKVLFRAGSGKPLAVLCLTVELQPHVVDQVFRFHHPELTFLKKAIRLPPWHTLPGAPVGTSSEDPPFHVRCSDPNIICETQSVGPGEPRDVFLKVASGPSPEVKDFFVTIYVDRWLATPVQTWQVHLHSLQRVDVSCITGQRTRLALVLRGTQTVRRVQAFSSHPQELTTDPRGVFVLPPHGVQDLHVSVRPCRPGSRFAHLHLVDVDAHQLVASWLLCLSCRPPLISKAFEIKLPAGSGRGANKRITYTNPYPSRRAYRLHSDHPHLLQFKEDAFQVGGGETYTIGLRFVSRQRAGEEEILIYINDHEDKNEETFCVKVIYQ B6028557C130E612 a7ywf3_bovin NPHP1 protein protein bovin Bos taurus (Bovine) Bovine MLARRQRDPLQSLQRRNQELKQQVDGLLFESRLKGALEASKRRDMYQRCIQLKQAIDENKNALQKLKKADEPAPVGNYYQKKEEEHNLLDKLTHQLQELAVSISRENVPETGALAEREEEENSDEEDEEEDDDEEESEESGGEDEETEEEEEEKQEGESQPEATSGEYIALGDFTAQQVGDLTFKKGEILCIIKKNSDGWWMAKNAKGNEGLIPKTYLEPYNKEGGQESSEGGSEEDTEVGDGTVDGAEVKQRTDSHWSAVRKAISEINTVDVLTAMGAIPAGFRPSTLFQLLEEGNQFRASYFLQPELTPSQLAFRDLMWDAKTGSIRSRPSRVSLILTLWSCKMIPLPGVSIQVLSRHVRLCLFDGSEVLSNIHTVRATWQPKKPKTWTFSPQVTGILPCLLDGDCFIRSNSSSPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDATGIPIPAKTYKLFLNGGTPYEKGVEVDPSVSRRAHGSVFHQLMTMRRQPQLLVKLRSLNRRSRSTLSLLPETLIGSMCCVHLLIFYRQILGDVLLKDRMSLNSADLISNPVLATFPKLLEESDIMDALRSSWAEKESTLKRSEKGDRELLKAVFLLVYHDCALPLLHSALLPPSRWAEEETEAARWKGIADFLKQNQENEGALQVLLSPEGVHEPFDISEQTYDFLGERRKNVT 868A6083F50915DC nphp1_human Nephrocystin-1 Juvenile nephronophthisis 1 protein NPHP1 NPH1 protein protein human Homo sapiens Human MLARRQRDPLQALRRRNQELKQQVDSLLSESQLKEALEPNKRQHIYQRCIQLKQAIDENKNALQKLSKADESAPVANYNQRKEEEHTLLDKLTQQLQGLAVTISRENITEVGAPTEEEEESESEDSEDSGGEEEDAEEEEEEKEENESHKWSTGEEYIAVGDFTAQQVGDLTFKKGEILLVIEKKPDGWWIAKDAKGNEGLVPRTYLEPYSEEEEGQESSEEGSEEDVEAVDETADGAEVKQRTDPHWSAVQKAISEAGIFCLVNHVSFCYLIVLMRNRMETVEDTNGSETGFRAWNVQSRGRIFLVSKPVLQINTVDVLTTMGAIPAGFRPSTLSQLLEEGNQFRANYFLQPELMPSQLAFRDLMWDATEGTIRSRPSRISLILTLWSCKMIPLPGMSIQVLSRHVRLCLFDGNKVLSNIHTVRATWQPKKPKTWTFSPQVTRILPCLLDGDCFIRSNSASPDLGILFELGISYIRNSTGERGELSCGWVFLKLFDASGVPIPAKTYELFLNGGTPYEKGIEVDPSISRRAHGSVFYQIMTMRRQPQLLVKLRSLNRRSRNVLSLLPETLIGNMCSIHLLIFYRQILGDVLLKDRMSLQSTDLISHPMLATFPMLLEQPDVMDALRSSWAGKESTLKRSEKRDKEFLKSTFLLVYHDCVLPLLHSTRLPPFRWAEEETETARWKVITDFLKQNQENQGALQALLSPDGVHEPFDLSEQTYDFLGEMRKNAV 270125F56F2C50F7 rpgr-nphp4-2 2 4 unspecified role unspecified role prey prey 12 unspecified role unspecified role bait bait physical association physical association 1B rpgr-nphp4-3 1 7 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain rabit-reticulocyte Oryctolagus cuniculus reticulocyte reticulocyte Reticulocytes 11 unspecified role unspecified role bait bait region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 25 22 physical association physical association 1D and E rpgr-nphp1-1 3 14 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey association association 1A and 2A nphp1-rpgr-1 3 14 unspecified role unspecified role bait bait 9 unspecified role unspecified role prey prey physical association physical association 2B rpgr-nphp4-4 1 15 unspecified role unspecified role prey prey region 35s radiolabel 35s radiolabel 35S s35 radiolabelled S35 s35 radiolabelled 35S S35 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain rabit-reticulocyte Oryctolagus cuniculus reticulocyte reticulocyte Reticulocytes 11 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined ecoli Escherichia coli (strain K12) 36 38 physical association physical association 2D and E rpgr-invs-1 3 8 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait association association 3C Detected in precipitate of NPHP4-depleted supernatant rpgr-cep290-3 3 6 unspecified role unspecified role prey prey 5 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey association association 4B Detected in precipitate of NPHP1-depleted supernatant nphp4-1 3 14 unspecified role unspecified role prey prey 13 unspecified role unspecified role bait bait Detected in precipitate of RPGR-depleted supernatant physical association physical association 5B Detected in precipitate of RPGR-depleted supernatant nphp1-nphp4-4 3 14 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey Detected in precipitate of RPGR-depleted supernatant physical association physical association 5C Detected in precipitate of RPGR-depleted supernatant