HPIDb Host Pathogen Interaction database http://www.agbase.msstate.edu/hpi/main.html Caveolin-1 mediates Salmonella invasion via the regulation of SopE-dependent Rac1 activation and actin reorganization. Caveolin-1 mediates Salmonella invasion via the regulation of SopE-dependent Rac1 activation and actin reorganization. J. Infect. Dis. (0022-1899) 2014 imex curation Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A., Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A. kacho@jnu.ac.kr Only protein-protein interactions imex curation human-hdf Homo sapiens diploid fibroblasts cells human-hdf cells human diploid fibroblasts cells pull down pull down western blot western blot Immuno blot Immuno blot Lim J.S., Shin M., Kim H.J., Kim K.S., Choy H.E., Cho K.A. kacho@jnu.ac.kr Accepted 2015-MAR-23 by ORCHARD J. Infect. Dis. (0022-1899) 2014 imex curation a0a0h3ngi8_salts Guanine nucleotide exchange factor sopE SL1344_2674 protein protein salts Salmonella typhimurium (strain SL1344) MTKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQNTP F636F6C437018D03 rac1_human Ras-related C3 botulinum toxin substrate 1 RAC1 MIG5 p21-Rac1 Ras-like protein TC25 Cell migration-inducing gene 5 protein TC25 protein protein human Homo sapiens Human MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKRKRKCLLL ACEDF83A45E5EA67 pak1_human Serine/threonine-protein kinase PAK 1 PAK1 p21-activated kinase 1 p65-PAK Alpha-PAK protein protein human Homo sapiens Human MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPGDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKNPQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNALNVKAVSETPAVPPVSEDEDDDDDDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEATKNNH DIP protein Q13153 original sequence version: 161 DIP protein Q13153 original sequence version: 122 DIP protein Q13153 original sequence version: 134 DIP protein Q13153 original sequence version: 165 1A95CD5F2195CD7B cav1_human Caveolin-1 CAV1 CAV protein protein human Homo sapiens Human MSGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHSFDGIWKASFTTFTVTKYWFYRLLSALFGIPMALIWGIYFAILSFLHIWAVVPCIKSFLIEIQCISRVYSIYVHTVCDPLFEAVGKIFSNVRINLQKEI DIP protein Q03135 original sequence version: 164 DIP protein Q03135 original sequence version: 119 DIP protein Q03135 original sequence version: 122 DIP protein Q03135-1 original sequence version: 122 DIP protein Q03135 original sequence version: 133 DIP protein Q03135 original sequence version: 155 DIP protein Q03135 original sequence version: 147 2424DE9B5E6521D5 rac1-sope-pak1-cav1-1 1 2 unspecified role unspecified role prey prey 3 unspecified role unspecified role prey prey RAC-1 was GTP bound 4 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey association association 4C and 5B pak1-cav1-1 1 3 unspecified role unspecified role prey prey RAC-1 was GTP bound 5 unspecified role unspecified role bait bait physical association physical association 4C, 5C and suppl. data 1 cav1-rac1-sope-1 1 2 unspecified role unspecified role prey prey 5 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey RAC-1 was GTP bound association association 4C pak1-cav1-rac1-1 1 3 unspecified role unspecified role prey prey RAC-1 was GTP bound 4 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey association association 4C, 5C, 5D and suppl. data 1 NSC23766, Rac1 inhibitor, inhibit Rac1-cav1 interaction pak1-cav1-sope-rac1-1 1 2 unspecified role unspecified role prey prey ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role prey prey RAC-1 was GTP bound 4 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey association association suppl. data 1 cav1-sope-rac1-1 1 2 unspecified role unspecified role prey prey ha tag ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 3 unspecified role unspecified role prey prey 5 unspecified role unspecified role prey prey association association suppl. data 1