UniProt UniProt http://www.uniprot.org The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 density sedimentation cosedimentation through density gradient density sedimentation western blot western blot Immuno blot Immuno blot Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti tag coip anti tag coimmunoprecipitation anti tag coip sequence tag sequence tag identification sequence tag Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics. J. Cell. Sci. (0021-9533) 2010 imex curation Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk 05-Sep-2017: Contacted by IntAct-Help. Only protein-protein interactions imex curation human-hela Homo sapiens epitheloid cervix carcinoma cells Human hela Human epitheloid cervix carcinoma HeLa cells derivation: cervix; epithelial; adenocarcinoma ATCC no:CCL-2 fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Harbour M.E., Breusegem S.Y., Antrobus R., Freeman C., Reid E., Seaman M.N. Authors did not respond to e-mail concerning used plasmids/constructs. A number of interactions cannot be curated. Origin of transfected VSP29-GFP according Collins et al 2005, PMID 15965486. Origin of transfected GFP-TBC1D5 according Seaman et al 2009, PMID 19531583. Origin of GFP-VPS35 according Gokool et al 2007, PMID 17696874. Origin of transfected FKBP15 according supplier (Kazusa). VPS26 is not included as interactor if identified by western blot as antibody specificity is not established (VPS26A vs VPS26B). FAM21 is not included as interactor derived from experiments using an anti-FAM21 antibody as the antibody specificity is not established (FAM21A-C) (relates to fig. 9). Origin of used FAM21 plasmid/construct according data from cDNA clone supplying site (Kazusa). Results from Supplementary figure 1 have not been included as the cell line used is not specified - HeLa or Mefs. mnjs100@cam.ac.uk Accepted 2017-AUG-29 AT 12:38 BST AT 12:38 BST by MGT J. Cell. Sci. (0021-9533) 2010 imex curation wasc4_human WASH complex subunit 4 WASHC4 KIAA1033 Strumpellin and WASH-interacting protein WASH complex subunit SWIP protein protein human Homo sapiens Human MAVETLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDSIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDASMVEGDCQIQMGRFISFLQELSCFVTRCYEVVMNVVHQLAALYISNKIAPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHITLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGVSVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTIDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIQKIPAAAKLLDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESILSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLVELLKAIEHMFYRRSMVVADSVSHITQHLQHQALHSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHARHLESYEILLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGMKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGVTPEGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCSSNAIRFVPDLEDIVNFEELVKEEGLAEETLKAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYILKLLDQYREFDSLHWFQSVREKYLKEIRAVAKQQNVQSASQDEKLLQTMNLTQKRLDVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSNGDLSDSTVSADPVVK FD073D5F21127DED tbcd5_human TBC1 domain family member 5 TBC1D5 KIAA0210 protein protein human Homo sapiens Human MYHSLSETRHPLQPEEQEVGIDPLSSYSNKSGGDSNKNGRRTSSTLDSEGTFNSYRKEWEELFVNNNYLATIRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIEELRAWYSNIKEIHITNPRKVVGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVKRTFPEMQFFQQENVRKILTDVLFCYARENEQLLYKQGMHELLAPIVFVLHCDHQAFLHASESAQPSEEMKTVLNPEYLEHDAYAVFSQLMETAEPWFSTFEHDGQKGKETLMTPIPFARPQDLGPTIAIVTKVNQIQDHLLKKHDIELYMHLNRLEIAPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLSLGLVDYIFVAMLLYIRDALISSNYQTCLGLLMHYPFIGDVHSLILKALFLRDPKRNPRPVTYQFHPNLDYYKARGADLMNKSRTNAKGAPLNINKVSNSLINFGRKLISPAMAPGSAGGPVPGGNSSSSSSVVIPTRTSAEAPSHHLQQQQQQQRLMKSESMPVQLNKGLSSKNISSSPSVESLPGGREFTGSPPSSATKKDSFFSNISRSRSHSKTMGRKESEEELEAQISFLQGQLNDLDAMCKYCAKVMDTHLVNIQDVILQENLEKEDQILVSLAGLKQIKDILKGSLRFNQSQLEAEENEQITIADNHYCSSGQGQGRGQGQSVQMSGAIKQASSETPGCTDRGNSDDFILISKDDDGSSARGSFSGQAQPLRTLRSTSGKSQAPVCSPLVFSDPLMGPASASSSNPSSSPDDDSSKDSGFTIVSPLDI 598CE3B436835E1D wash2_human WAS protein family homolog 2 WASH2P FAM39B CXYorf1-like protein on chromosome 2 Protein FAM39B protein protein human Homo sapiens Human MTPVRMQHSLAGQTYAVPLIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPGIANDLMYIADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGRATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPLPPPQQPQAEEDEDDWES 54FD1BB405E391DF wac2a_human WASH complex subunit 2A WASHC2A FAM21A FAM21B protein protein human Homo sapiens Human MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 8F0F755EB1493EA7 vps29_mouse Vacuolar protein sorting-associated protein 29 Vps29 Vesicle protein sorting 29 protein protein mouse Mus musculus Mouse MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKS Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro) mint 6CDCDE6B720C9BF8 wash1_human WASH complex subunit 1 WASHC1 CXYorf1-like protein on chromosome 9 FAM39E Protein FAM39E WAS protein family homolog 1 WASH1 protein protein human Homo sapiens Human MTPVRMQHSLAGQTYAVPFIQPDLRREEAVQQMADALQYLQKVSGDIFSRISQQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPGRLQEYGSIFTGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIHVPSYLPDLPGIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKVDLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDSSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAKLRSMKERKLEKQQQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFVRVSDSIPPLPPPQQPQAEEDEDDWES DBD5DEAFB7019B3E wac2c_human WASH complex subunit 2C VPEF WASHC2C FAM21C KIAA0592 Vaccinia virus penetration factor protein protein human Homo sapiens Human MMNRTTPDQELVPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNQHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAMGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEASQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSLKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTRKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSYSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASNLKGASLLPGKLPTSVSLFDDEDEEDNLFGGTAAKKQTLSLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDKEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGCDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVNSFKNQKHPESIQGSKEKGIWKPETPQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSEAEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDTSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSSSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSTGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ 156651EE158BE32F vps29_human Vacuolar protein sorting-associated protein 29 Vesicle protein sorting 29 PEP11 homolog VPS29 DC7 DC15 MDS007 protein protein human Homo sapiens Human MLVLVLGDLHIPHRCNSLPAKFKKLLVPGKIQHILCTGNLCTKESYDYLKTLAGDVHIVRGDFDENLNYPEQKVVTVGQFKIGLIHGHQVIPWGDMASLALLQRQFDVDILISGHTHKFEAFEHENKFYINPGSATGAYNALETNIIPSFVLMDIQASTVVTYVYQLIGDDVKVERIEYKKP DIP protein Q9UBQ0 original sequence version: 51 DIP protein Q9UBQ0-1 original sequence version: 117 DIP protein Q9UBQ0 original sequence version: 117 DIP protein Q9UBQ0 original sequence version: 129 6E0CDE6B720C9BF8 vps35_mouse Vacuolar protein sorting-associated protein 35 Vesicle protein sorting 35 Maternal-embryonic 3 Vps35 Mem3 protein protein mouse Mus musculus Mouse MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPAEIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSDDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSQMDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRSRRESPESEGPIYEGLIL DIP protein Q9EQH3 original sequence version: 93 DIP protein Q9EQH3 original sequence version: 57 2ABD338111D641CC caza2_human F-actin-capping protein subunit alpha-2 CapZ alpha-2 CAPZA2 protein protein human Homo sapiens Human MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA DIP protein P47755 original sequence version: null B5E1B617A38E758B vp26a_human Vacuolar protein sorting-associated protein 26A VPS26A VPS26 Vesicle protein sorting 26A protein protein human Homo sapiens Human MSFLGGFFGPICEIDIVLNDGETRKMAEMKTEDGKVEKHYLFYDGESVSGKVNLAFKQPGKRLEHQGIRIEFVGQIELFNDKSNTHEFVNLVKELALPGELTQSRSYDFEFMQVEKPYESYIGANVRLRYFLKVTIVRRLTDLVKEYDLIVHQLATYPDVNNSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIQHMELQLIKKEITGIGPSTTTETETIAKYEIMDGAPVKGESIPIRLFLAGYDPTPTMRDVNKKFSVRYFLNLVLVDEEDRRYFKQQEIILWRKAPEKLRKQRTNFHQRFESPESQASAEQPEM DIP protein O75436 original sequence version: 115 DIP protein O75436 original sequence version: 53 DIP protein O75436 original sequence version: 113 DIP protein O75436-1 original sequence version: 113 DIP protein O75436 original sequence version: 123 BD3B2EAA6CFCBFA9 caza1_human F-actin-capping protein subunit alpha-1 CAPZA1 CapZ alpha-1 protein protein human Homo sapiens Human MADFDDRVSDEEKVRIAAKFITHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNMDQFTPVKIEGYEDQVLITEHGDLGNSRFLDPRNKISFKFDHLRKEASDPQPEEADGGLKSWRESCDSALRAYVKDHYSNGFCTVYAKTIDGQQTIIACIESHQFQPKNFWNGRWRSEWKFTITPPTAQVVGVLKIQVHYYEDGNVQLVSHKDVQDSLTVSNEAQTAKEFIKIIENAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA 0F47ADAB6A3689DD wash6_human WAS protein family homolog 6 WASH6P CXYorf1 FAM39A Protein FAM39A protein protein human Homo sapiens Human MAFHEMQAHKNALGTSGEQQAADITGPTPHQGGWKQVEQSRSQVQAIGEKVSLAQAKIEKIKGSKKAIKVFSSAKYPAPERLQEYGSIFTGAQDPGLQRRPRHRIQSKHRPLDERALQEKLKDFPVCVSTKPEPEDDAEEGLGGLPSNISSVSSLLLFNTTENLYKKYVFLDPLAGAVTKTHVMLGAETEEKLFDAPLSISKREQLEQQVPENYFYVPDLGQVPEIDVPSYLPDLPSIANDLMYSADLGPGIAPSAPGTIPELPTFHTEVAEPLKADLQDGVLTPPPPPPPPPPAPEVLASAPPLPPSTAAPVGQGARQDDGSSSASPSVQGAPREVVDPSGGWATLLESIRQAGGIGKAKLRSMKERKLEKKKQKEQEQVRATSQGGHLMSDLFNKLVMRRKGISGKGPGAGEGPGGAFARVSDSIPPVPPPQQPQAEEDEDDWES 7B1217DC3CF9DDAA snx1_human Sorting nexin-1 SNX1 protein protein human Homo sapiens Human MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS DIP protein Q13596 original sequence version: 129 6AC8AA0A589513E3 vp26b_human Vacuolar protein sorting-associated protein 26B Vesicle protein sorting 26B VPS26B protein protein human Homo sapiens Human MSFFGFGQSVEVEILLNDAESRKRAEHKTEDGKKEKYFLFYDGETVSGKVSLALKNPNKRLEHQGIKIEFIGQIELYYDRGNHHEFVSLVKDLARPGEITQSQAFDFEFTHVEKPYESYTGQNVKLRYFLRATISRRLNDVVKEMDIVVHTLSTYPELNSSIKMEVGIEDCLHIEFEYNKSKYHLKDVIVGKIYFLLVRIKIKHMEIDIIKRETTGTGPNVYHENDTIAKYEIMDGAPVRGESIPIRLFLAGYELTPTMRDINKKFSVRYYLNLVLIDEEERRYFKQQEVVLWRKGDIVRKSMSHQAAIASQRFEGTTSLGEVRTPSQLSDNNCRQ 1C07D0ABA7797A12 fkb15_human FK506-binding protein 15 FKBP15 KIAA0674 133 kDa FK506-binding protein WASP- and FKBP-like protein protein protein human Homo sapiens Human MFGAGDEDDTDFLSPSGGARLASLFGLDQAAAGHGNEFFQYTAPKQPKKGQGTAATGNQATPKTAPATMSTPTILVATAVHAYRYTNGQYVKQGKFGAAVLGNHTAREYRILLYISQQQPVTVARIHVNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVEFNKQVCIAKCNSTSSLDAVLSQDLIVADGPAVEVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVPPACAVGSEGVIGWTQATDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIPGADNLSADPVVSPPTSIPFKSGEPALRTKSNSLSEQLAINTSPDAVKAKLISRMAKMGQPMLPILPPQLDSNDSEIEDVNTLQGGGQPVVTPSVQPSLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQSFQPYAGMQAYAYPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTEARQHNTEIRMAVSKVADKMDHLMTKVEELQKHSAGNSMLIPSMSVTMETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSNLMMEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRREFELEESYNGRTILGTIMNTIKMVTLQLLNQQEQEKEESSSEEEEEKAEERPRRPSQEQSASASSGQPQAPLNRERPESPMVPSEQVVEEAVPLPPQALTTSQDGHRRKGDSEAEALSEIKDGSLPPELSCIPSHRVLGPPTSIPPEPLGPVSMDSECEESLAASPMAAKPDNPSGKVCVREVAPDGPLQESSTRLSLTSDPEEGDPLALGPESPGEPQPPQLKKDDVTSSTGPHKELSSTEAGSTVAGAALRPSHHSQRSSLSGDEEDELFKGATLKALRPKAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDDIDWLG 86563D82B540B51D wasc5_human WASH complex subunit 5 WASHC5 KIAA0196 Strumpellin WASH complex subunit strumpellin protein protein human Homo sapiens Human MLDFLAENNLCGQAILRIVSCGNAIIAELLRLSEFIPAVFRLKDRADQQKYGDIIFDFSYFKGPELWESKLDAKPELQDLDEEFRENNIEIVTRFYLAFQSVHKYIVDLNRYLDDLNEGVYIQQTLETVLLNEDGKQLLCEALYLYGVMLLVIDQKIEGEVRERMLVSYYRYSAARSSADSNMDDICKLLRSTGYSSQPGAKRPSNYPESYFQRVPINESFISMVIGRLRSDDIYNQVSAYPLPEHRSTALANQAAMLYVILYFEPSILHTHQAKMREIVDKYFPDNWVISIYMGITVNLVDAWEPYKAAKTALNNTLDLSNVREQASRYATVSERVHAQVQQFLKEGYLREEMVLDNIPKLLNCLRDCNVAIRWLMLHTADSACDPNNKRLRQIKDQILTDSRYNPRILFQLLLDTAQFEFILKEMFKQMLSEKQTKWEHYKKEGSERMTELADVFSGVKPLTRVEKNENLQAWFREISKQILSLNYDDSTAAGRKTVQLIQALEEVQEFHQLESNLQVCQFLADTRKFLHQMIRTINIKEEVLITMQIVGDLSFAWQLIDSFTSIMQESIRVNPSMVTKLRATFLKLASALDLPLLRINQANSPDLLSVSQYYSGELVSYVRKVLQIIPESMFTSLLKIIKLQTHDIIEVPTRLDKDKLRDYAQLGPRYEVAKLTHAISIFTEGILMMKTTLVGIIKVDPKQLLEDGIRKELVKRVAFALHRGLIFNPRAKPSELMPKLKELGATMDGFHRSFEYIQDYVNIYGLKIWQEEVSRIINYNVEQECNNFLRTKIQDWQSMYQSTHIPIPKFTPVDESVTFIGRLCREILRITDPKMTCHIDQLNTWYDMKTHQEVTSSRLFSEIQTTLGTFGLNGLDRLLCFMIVKELQNFLSMFQKIILRDRTVQDTLKTLMNAVSPLKSIVANSNKIYFSAIAKTQKIWTAYLEAIMKVGQMQILRQQIANELNYSCRFDSKHLAAALENLNKALLADIEAHYQDPSLPYPKEDNTLLYEITAYLEAAGIHNPLNKIYITTKRLPYFPIVNFLFLIAQLPKLQYNKNLGMVCRKPTDPVDWPPLVLGLLTLLKQFHSRYTEQFLALIGQFICSTVEQCTSQKIPEIPADVVGALLFLEDYVRYTKLPRRVAEAHVPNFIFDEFRTVL D6156D359981FC5F capzb_human F-actin-capping protein subunit beta CAPZB CapZ beta protein protein human Homo sapiens Human MSDQQLDCALDLMRRLPPQQIEKNLSDLIDLVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDN ABA1621F9E0152A6 vps35_human Vacuolar protein sorting-associated protein 35 Vesicle protein sorting 35 Maternal-embryonic 3 VPS35 MEM3 TCCCTA00141 protein protein human Homo sapiens Human MPTTQQSPQDEQEKLLDEAIQAVKVQSFQMKRCLDKNKLMDALKHASNMLGELRTSMLSPKSYYELYMAISDELHYLEVYLTDEFAKGRKVADLYELVQYAGNIIPRLYLLITVGVVYVKSFPQSRKDILKDLVEMCRGVQHPLRGLFLRNYLLQCTRNILPDEGEPTDEETTGDISDSMDFVLLNFAEMNKLWVRMQHQGHSRDREKRERERQELRILVGTNLVRLSQLEGVNVERYKQIVLTGILEQVVNCRDALAQEYLMECIIQVFPDEFHLQTLNPFLRACAELHQNVNVKNIIIALIDRLALFAHREDGPGIPADIKLFDIFSQQVATVIQSRQDMPSEDVVSLQVSLINLAMKCYPDRVDYVDKVLETTVEIFNKLNLEHIATSSAVSKELTRLLKIPVDTYNNILTVLKLKHFHPLFEYFDYESRKSMSCYVLSNVLDYNTEIVSQDQVDSIMNLVSTLIQDQPDQPVEDPDPEDFADEQSLVGRFIHLLRSEDPDQQYLILNTARKHFGAGGNQRIRFTLPPLVFAAYQLAFRYKENSKVDDKWEKKCQKIFSFAHQTISALIKAELAELPLRLFLQGALAAGEIGFENHETVAYEFMSQAFSLYEDEISDSKAQLAAITLIIGTFERMKCFSEENHEPLRTQCALAASKLLKKPDQGRAVSTCAHLFWSGRNTDKNGEELHGGKRVMECLKKALKIANQCMDPSLQVQLFIEILNRYIYFYEKENDAVTIQVLNQLIQKIREDLPNLESSEETEQINKHFHNTLEHLRLRRESPESEGPIYEGLIL DIP protein Q96QK1 original sequence version: 118 DIP protein Q96QK1 original sequence version: 44 DIP protein Q96QK1 original sequence version: 117 DIP protein Q96QK1 original sequence version: 127 28D2DD1C6B920A0A vps29-capza1-1 3 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection Q9QZ88:p.Ile91Ser mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength certain certain sequence position certain certain certain sequence position certain I S Wed May 02 14:33:46 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile91ser' Tue Jun 30 17:31:42 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile91Ser' c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 12 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 7 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey association association 1A tbc1d5-vps29-2 5 11 unspecified role unspecified role bait bait Q9QZ88:p.Leu152Glu mutation disrupting strength mutation disrupting interaction strength mutation disrupting strength certain certain sequence position certain certain certain sequence position certain L E Wed May 02 19:26:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu152glu' Tue Jun 30 16:25:29 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu152Glu' 8 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association 3A and B, S2A, Table 2 vps29-vps35-3 5 11 unspecified role unspecified role bait bait Q9QZ88:p.Leu152Glu mutation with no effect mutation with no effect mutation with no effect mutation not affecting interaction certain certain sequence position certain certain certain sequence position certain L E Wed May 02 15:15:55 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu152glu' Tue Jun 30 17:13:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu152Glu' 15 unspecified role unspecified role prey prey physical association physical association 3B A VPS29 leu152glu mutation does not change the association. tbc1d5-vps35-1 4 25 unspecified role unspecified role prey prey cell lysate cell lysate 8 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain TBC1D5 mutant constructs R169A, Q204A, R169A, Q204A and SST43AAA also showed association physical association physical association weak interaction 3C vps29-fkbp15-1 4 25 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined association association VPS26A and/or VPS26B was also detected 5B hspa8-tbc1d5-1 3 14 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 8 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q92609:p.[Arg169Ala;Gln204Ala] mutation mutation certain certain sequence position certain certain certain sequence position certain R A certain certain sequence position certain certain certain sequence position certain Q A Wed May 02 19:44:21 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg169ala,gln204ala' Tue Jun 30 19:05:47 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg169Ala;Gln204Ala]' 21 unspecified role unspecified role prey prey association association 5c fam21c-fkbp15-1 3 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 17 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 19 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 7 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey association association 5C, Supp. table 1 capzb-fam21a-2 3 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range Q9QZ88:p.Leu152Glu mutation mutation certain certain sequence position certain certain certain sequence position certain L E Wed May 02 17:45:59 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu152glu' Tue Jun 30 16:31:52 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu152Glu' 9 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 7 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 17 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 13 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey association association 5C capza1-capza2-1 3 17 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 25 unspecified role unspecified role prey prey 16 unspecified role unspecified role prey prey 19 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 24 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 7 unspecified role unspecified role prey prey 18 unspecified role unspecified role prey prey 22 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey 21 unspecified role unspecified role prey prey association association 5C, supplemental table S1 fkbp15-vps29-3 1 11 unspecified role unspecified role neutral component neutral component region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 25 unspecified role unspecified role neutral component neutral component 22 unspecified role unspecified role neutral component neutral component colocalization colocalization 6B VPS26A or VPS26B comigrated fkbp15-vps29-1 1 22 unspecified role unspecified role neutral component neutral component 12 unspecified role unspecified role neutral component neutral component 23 unspecified role unspecified role neutral component neutral component colocalization colocalization 6B vps29-kiaa0196-1 4 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 25 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey association association VPS26A and/or VPS26B was also detected 6C Association of WASHC5/strumpellin was decreased upon treating cells independently with siRNAs to KIAA1033, RAB7 and SNX1. siRNAs to SNX3, WASH1, FKBP15 and TBC1D5 had no effect. vps35-vps29-8 5 11 unspecified role unspecified role prey prey physical association physical association Table 2 vps35-fam21c-1 5 13 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait physical association physical association Table 2 vps35-fkbp15-1 5 15 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association Table 2 and 2B fkbp15-vps29-2 5 11 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 fkbp15-vps35-1 5 22 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 fkbp15-fam21c-1 5 13 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 fkbp15-fkbp15-1 5 22 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association Table 2 snx1-kiaa0196-1 2 20 unspecified role unspecified role bait bait 23 unspecified role unspecified role prey prey physical association physical association 9A and B Treating cells with siRNA to TBC1D5 decreased association. vps29-tbc1d5-2 4 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection Q9QZ88:p.Ile91Ser mutation mutation certain certain sequence position certain certain certain sequence position certain I S Wed May 02 18:01:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ile91ser' Tue Jun 30 17:53:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ile91Ser' c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 8 unspecified role unspecified role prey prey association association 5B vps29-vps35-13 4 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range Q9QZ88:p.Leu152Glu mutation mutation certain certain sequence position certain certain certain sequence position certain L E Wed May 02 18:39:08 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'leu152glu' Tue Jun 30 17:11:41 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Leu152Glu' 22 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey association association 5B VPS26A and/or VPS26B was also detected vps29-vps35-14 4 11 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection c-terminus gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range 22 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey 12 unspecified role unspecified role prey prey 23 unspecified role unspecified role prey prey association association 5B VPS26A and/or VPS26B was also detected washc5-snx1-1 2 20 unspecified role unspecified role prey prey 23 unspecified role unspecified role bait bait physical association physical association 9A Treating cells with siRNA to TBC1D5 decreased association. fkbp15-washc1-1 6 12 unspecified role unspecified role neutral component neutral component 22 unspecified role unspecified role neutral component neutral component colocalization colocalization 7D tbc1d5-vps35-2 4 23 unspecified role unspecified role prey prey 25 unspecified role unspecified role prey prey cell lysate cell lysate 8 unspecified role unspecified role bait bait nucl transfection nucleic acid transfection nucl transfection region gfp tag green fluorescent protein tag GFP green fluorescent protein GFP green fluorescent protein gfp tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Q92609:p.[Arg169Ala;Gln204Ala] mutation mutation certain certain sequence position certain certain certain sequence position certain Q A certain certain sequence position certain certain certain sequence position certain R A Thu Nov 02 15:34:39 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'arg169ala,gln204ala[169-169], [204-204] mutation' Wed May 02 19:22:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'arg169ala,gln204ala' Tue Jun 30 17:46:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Arg169Ala;Gln204Ala]' TBC1D5 mutant constructs R169A, Q204A, R169A, Q204A and SST43AAA also showed association association association 5B VPS26A and/or VPS26B was also detected fkbp15-washc1-2 6 12 unspecified role unspecified role neutral component neutral component 20 unspecified role unspecified role neutral component neutral component colocalization colocalization 7A