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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>UniProt</shortLabel>
        <fullName>UniProt</fullName>
      </names>
      <xref>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.uniprot.org</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="17240984" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9544213" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-22715" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Discovery of two cyanobacterial phenylalanine ammonia lyases: kinetic and structural characterization.</attribute>
            <attribute name="journal" nameAc="MI:0885">Biochemistry (0006-2960)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2007</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Moffitt M.C., Louie G.V., Bowman M.E., Pence J., Noel J.P., Moore B.S.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">bsmoore@ucsd.edu</attribute>
            <attribute name="author-announcement">21-Jul-2014: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="17240984" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22715" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Moffitt M.C., Louie G.V., Bowman M.E., Pence J., Noel J.P., Moore B.S.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">bsmoore@ucsd.edu</attribute>
          <attribute name="accepted">Accepted 2014-JUN-26 by MGT</attribute>
          <attribute name="journal" nameAc="MI:0885">Biochemistry (0006-2960)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2007</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>pal_triv2</shortLabel>
          <fullName>Phenylalanine ammonia-lyase</fullName>
          <alias type="locus name" typeAc="MI:0305">Ava_3988</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q3M5Z3" version="TrEMBL_64" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="ABA23593" version="SP_98" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9544234" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001106"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024083"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008948"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022313"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NYN"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3CZO"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5LTM"/>
          <secondaryRef db="ensemblbacteria" id="ABA23593" version="SP_98" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="Ava_3988" version="SP_98" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_98"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009072" version="SP_98"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009699" version="SP_98"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009800" version="SP_98"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045548" version="SP_98"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" version="SP_98"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="240292">
          <names>
            <shortLabel>anavt</shortLabel>
            <fullName>Anabaena variabilis (strain ATCC 29413 / PCC 7937)</fullName>
          </names>
        </organism>
        <sequence>MKTLSQAQSKTSSQQFSFTGNSSANVIIGNQKLTINDVARVARNGTLVSLTNNTDILQGIQASCDYINNAVESGEPIYGVTSGFGGMANVAISREQASELQTNLVWFLKTGAGNKLPLADVRAAMLLRANSHMRGASGIRLELIKRMEIFLNAGVTPYVYEFGSIGASGDLVPLSYITGSLIGLDPSFKVDFNGKEMDAPTALRQLNLSPLTLLPKEGLAMMNGTSVMTGIAANCVYDTQILTAIAMGVHALDIQALNGTNQSFHPFIHNSKPHPGQLWAADQMISLLANSQLVRDELDGKHDYRDHELIQDRYSLRCLPQYLGPIVDGISQIAKQIEIEINSVTDNPLIDVDNQASYHGGNFLGQYVGMGMDHLRYYIGLLAKHLDVQIALLASPEFSNGLPPSLLGNRERKVNMGLKGLQICGNSIMPLLTFYGNSIADRFPTHAEQFNQNINSQGYTSATLARRSVDIFQNYVAIALMFGVQAVDLRTYKKTGHYDARACLSPATERLYSAVRHVVGQKPTSDRPYIWNDNEQGLDEHIARISADIAAGGVIVQAVQDILPCLH</sequence>
        <attributeList>
          <attribute name="crc64">20DC10E873A061FA</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>pal_nosp7</shortLabel>
          <fullName>Phenylalanine ammonia-lyase</fullName>
          <alias type="locus name" typeAc="MI:0305">Npun_R2068</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="B2J528" version="TrEMBL_38" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblbacteria" id="ACC80688" version="SP_65" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9544250" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="WP_012408693.1"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001106"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024083"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008948"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR022313"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NYF"/>
          <secondaryRef db="ensemblbacteria" id="ACC80688" version="SP_65" refType="transcript"/>
          <secondaryRef db="ensemblbacteria" id="Npun_R2068" version="SP_65" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_65"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009072" version="SP_65"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009699" version="SP_65"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0009800" version="SP_65"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045548" version="SP_65"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051289" version="SP_65"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="63737">
          <names>
            <shortLabel>nosp7</shortLabel>
            <fullName>Nostoc punctiforme (strain ATCC 29133 / PCC 73102)</fullName>
          </names>
        </organism>
        <sequence>MNITSLQQNITRSWQIPFTNSSDSIVTVGDRNLTIDEVVNVARHGTQVRLTDNADVIRGVQASCDYINNAVETAQPIYGVTSGFGGMADVVISREQAAELQTNLIWFLKSGAGNKLSLADVRAAMLLRANSHLYGASGIRLELIQRIETFLNAGVTPHVYEFGSIGASGDLVPLSYITGALIGLDPSFTVDFDGKEMDAVTALSRLGLPKLQLQPKEGLAMMNGTSVMTGIAANCVYDAKVLLALTMGVHALAIQGLYGTNQSFHPFIHQCKPHPGQLWTADQMFSLLKDSSLVREELDGKHEYRGKDLIQDRYSLRCLAQFIGPIVDGVSEITKQIEVEMNSVTDNPLIDVENQVSYHGGNFLGQYVGVTMDRLRYYIGLLAKHIDVQIALLVSPEFSNGLPPSLVGNSDRKVNMGLKGLQISGNSIMPLLSFYGNSLADRFPTHAEQFNQNINSQGYISANLTRRSVDIFQNYMAIALMFGVQAVDLRTYKMKGHYDARTCLSPNTVQLYTAVCEVVGKPLTSVRPYIWNDNEQCLDEHIARISADIAGGGLIVQAVEHIFSSLKST</sequence>
        <attributeList>
          <attribute name="crc64">F4EA2BF170FF0063</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4" imexId="IM-22715-1">
        <names>
          <shortLabel>q3m5z3</shortLabel>
        </names>
        <xref>
          <primaryRef db="wwpdb" dbAc="MI:0805" id="2nyn" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9544230" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22715-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <xref>
              <primaryRef db="pdbj" dbAc="MI:0806" id="2nyn" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="4"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">fig 1</attribute>
          <attribute name="3d-r-factors" nameAc="MI:0631">R-factor: 0.223, R-free: 0.242</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">1.90 A</attribute>
        </attributeList>
      </interaction>
      <interaction id="6" imexId="IM-22715-2">
        <names>
          <shortLabel>b2j528-1</shortLabel>
        </names>
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          <primaryRef db="wwpdb" dbAc="MI:0805" id="2nyf" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-9544265" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-22715-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
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                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="4"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">fig 1</attribute>
          <attribute name="3d-r-factors" nameAc="MI:0631">R-factor: 0.247, R-free: 0.305</attribute>
          <attribute name="3d-resolution" nameAc="MI:0632">2.50 A</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>