IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties. Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties. Cancer Cell (1535-6108) 2013 imex curation Bono F., De Smet F., Herbert C., De Bock K., Georgiadou M., Fons P., Tjwa M., Alcouffe C., Ny A., Bianciotto M., Jonckx B., Murakami M., Lanahan A.A., Michielsen C., Sibrac D., Dol-Gleizes F., Mazzone M., Zacchigna S., Herault J.P., Fischer C., Rigon P., Ruiz de Almodovar C., Claes F., Blanc I., Poesen K., Zhang J., Segura I., Gueguen G., Bordes M.F., Lambrechts D., Broussy R., van de Wouwer M., Michaux C., Shimada T., Jean I., Blacher S., Noel A., Motte P., Rom E., Rakic J.M., Katsuma S., Schaeffer P., Yayon A., Van Schepdael A., Schwalbe H., Gervasio F.L., Carmeliet G., Rozensky J., Dewerchin M., Simons M., Christopoulos A., Herbert J.M., Carmeliet P. Cancer - Interactions investigated in the context of cancer Phosphorylation/Kinase assays not included as ADP-Glo Kinase Assay (Promega) - does not indicate what the substrate might be. SPA: I have entered all as " Physical associations. NO experimental info is available as to receptor source nor how the receptors/other mols were coupled to the beads (antibody?).The Cell based assays using "isolated enz" have been entered as "direct", as have the 2 screening interactions. For the 125I-FGF-2 FGFR-1 interaction SPA beads were coated with protein A-with FGFR-1IIIcß - Fc chimera soluble receptor. Table S2 Binding assays were carried out by Sanofi (according to the authors). The bead coatings used are not known; nor are the cells used in the Cell Biology assays known. The authors have confirmed these proteins/constructs are of Human origin:-125I-FGF-2, unlabeled FGF-2 and FGFR1-D1D2D3/Fc= FGFR-1IIIcß-Fc chimera (R&D system cat no 661-FR-050), FGFR2-D2D3 fragment. The authors also state that the receptor/ligand interactions shown in Table S2 used Human molecules (where relevant) - to the best of their knowledge. peter.carmeliet@vib-kuleuven.be 19-Jun-2013: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro spa scintillation proximity assay SPA RIA Radio Immuno Assay spa antibody detection identification by antibody antibody detection Bono F., De Smet F., Herbert C., De Bock K., Georgiadou M., Fons P., Tjwa M., Alcouffe C., Ny A., Bianciotto M., Jonckx B., Murakami M., Lanahan A.A., Michielsen C., Sibrac D., Dol-Gleizes F., Mazzone M., Zacchigna S., Herault J.P., Fischer C., Rigon P., Ruiz de Almodovar C., Claes F., Blanc I., Poesen K., Zhang J., Segura I., Gueguen G., Bordes M.F., Lambrechts D., Broussy R., van de Wouwer M., Michaux C., Shimada T., Jean I., Blacher S., Noel A., Motte P., Rom E., Rakic J.M., Katsuma S., Schaeffer P., Yayon A., Van Schepdael A., Schwalbe H., Gervasio F.L., Carmeliet G., Rozensky J., Dewerchin M., Simons M., Christopoulos A., Herbert J.M., Carmeliet P. Cancer - Interactions investigated in the context of cancer Phosphorylation/Kinase assays not included as ADP-Glo Kinase Assay (Promega) - does not indicate what the substrate might be. SPA: I have entered all as " Physical associations. NO experimental info is available as to receptor source nor how the receptors/other mols were coupled to the beads (antibody?).The Cell based assays using "isolated enz" have been entered as "direct", as have the 2 screening interactions. For the 125I-FGF-2 FGFR-1 interaction SPA beads were coated with protein A-with FGFR-1IIIcß - Fc chimera soluble receptor. Table S2 Binding assays were carried out by Sanofi (according to the authors). The bead coatings used are not known; nor are the cells used in the Cell Biology assays known. The authors have confirmed these proteins/constructs are of Human origin:-125I-FGF-2, unlabeled FGF-2 and FGFR1-D1D2D3/Fc= FGFR-1IIIcß-Fc chimera (R&D system cat no 661-FR-050), FGFR2-D2D3 fragment. The authors also state that the receptor/ligand interactions shown in Table S2 used Human molecules (where relevant) - to the best of their knowledge. The authors have confirmed these proteins/constructs are of Human origin:-125I-FGF-2, unlabeled FGF-2 and FGFR1-D1D2D3/Fc= FGFR-1IIIcß-Fc chimera (R&D system cat no 661-FR-050), FGFR2-D2D3 fragment. The authors also state that the receptor/ligand interactions shown in Table S2 used Human molecules (where relevant) - to the best of their knowledge. peter.carmeliet@vib-kuleuven.be Accepted 2013-MAY-20 by ORCHARD 19-Jun-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties. Inhibition of Tumor Angiogenesis and Growth by a Small-Molecule Multi-FGF Receptor Blocker with Allosteric Properties. Cancer Cell (1535-6108) 2013 imex curation Bono F., De Smet F., Herbert C., De Bock K., Georgiadou M., Fons P., Tjwa M., Alcouffe C., Ny A., Bianciotto M., Jonckx B., Murakami M., Lanahan A.A., Michielsen C., Sibrac D., Dol-Gleizes F., Mazzone M., Zacchigna S., Herault J.P., Fischer C., Rigon P., Ruiz de Almodovar C., Claes F., Blanc I., Poesen K., Zhang J., Segura I., Gueguen G., Bordes M.F., Lambrechts D., Broussy R., van de Wouwer M., Michaux C., Shimada T., Jean I., Blacher S., Noel A., Motte P., Rom E., Rakic J.M., Katsuma S., Schaeffer P., Yayon A., Van Schepdael A., Schwalbe H., Gervasio F.L., Carmeliet G., Rozensky J., Dewerchin M., Simons M., Christopoulos A., Herbert J.M., Carmeliet P. Cancer - Interactions investigated in the context of cancer Phosphorylation/Kinase assays not included as ADP-Glo Kinase Assay (Promega) - does not indicate what the substrate might be. SPA: I have entered all as " Physical associations. NO experimental info is available as to receptor source nor how the receptors/other mols were coupled to the beads (antibody?).The Cell based assays using "isolated enz" have been entered as "direct", as have the 2 screening interactions. For the 125I-FGF-2 FGFR-1 interaction SPA beads were coated with protein A-with FGFR-1IIIcß - Fc chimera soluble receptor. Table S2 Binding assays were carried out by Sanofi (according to the authors). The bead coatings used are not known; nor are the cells used in the Cell Biology assays known. The authors have confirmed these proteins/constructs are of Human origin:-125I-FGF-2, unlabeled FGF-2 and FGFR1-D1D2D3/Fc= FGFR-1IIIcß-Fc chimera (R&D system cat no 661-FR-050), FGFR2-D2D3 fragment. The authors also state that the receptor/ligand interactions shown in Table S2 used Human molecules (where relevant) - to the best of their knowledge. peter.carmeliet@vib-kuleuven.be 19-Jun-2013: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro ms interact detect detection by mass spectrometry ms interact detect ms participant Identification by mass spectrometry ms participant Bono F., De Smet F., Herbert C., De Bock K., Georgiadou M., Fons P., Tjwa M., Alcouffe C., Ny A., Bianciotto M., Jonckx B., Murakami M., Lanahan A.A., Michielsen C., Sibrac D., Dol-Gleizes F., Mazzone M., Zacchigna S., Herault J.P., Fischer C., Rigon P., Ruiz de Almodovar C., Claes F., Blanc I., Poesen K., Zhang J., Segura I., Gueguen G., Bordes M.F., Lambrechts D., Broussy R., van de Wouwer M., Michaux C., Shimada T., Jean I., Blacher S., Noel A., Motte P., Rom E., Rakic J.M., Katsuma S., Schaeffer P., Yayon A., Van Schepdael A., Schwalbe H., Gervasio F.L., Carmeliet G., Rozensky J., Dewerchin M., Simons M., Christopoulos A., Herbert J.M., Carmeliet P. Cancer - Interactions investigated in the context of cancer Phosphorylation/Kinase assays not included as ADP-Glo Kinase Assay (Promega) - does not indicate what the substrate might be. SPA: I have entered all as " Physical associations. NO experimental info is available as to receptor source nor how the receptors/other mols were coupled to the beads (antibody?).The Cell based assays using "isolated enz" have been entered as "direct", as have the 2 screening interactions. For the 125I-FGF-2 FGFR-1 interaction SPA beads were coated with protein A-with FGFR-1IIIcß - Fc chimera soluble receptor. Table S2 Binding assays were carried out by Sanofi (according to the authors). The bead coatings used are not known; nor are the cells used in the Cell Biology assays known. The authors have confirmed these proteins/constructs are of Human origin:-125I-FGF-2, unlabeled FGF-2 and FGFR1-D1D2D3/Fc= FGFR-1IIIcß-Fc chimera (R&D system cat no 661-FR-050), FGFR2-D2D3 fragment. The authors also state that the receptor/ligand interactions shown in Table S2 used Human molecules (where relevant) - to the best of their knowledge. peter.carmeliet@vib-kuleuven.be Accepted 2013-MAY-20 by ORCHARD 19-Jun-2013: Contacted by IntAct-Help. Cancer Cell (1535-6108) 2013 Only protein-protein interactions imex curation cgs-21680 CGS-21680 small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) cac1b_human Voltage-dependent N-type calcium channel subunit alpha-1B Voltage-gated calcium channel subunit alpha Cav2.2 Calcium channel, L type, alpha-1 polypeptide isoform 5 Brain calcium channel III CACNA1B CACH5 CACNL1A5 protein protein human Homo sapiens Human MVRFGDELGGRYGGPGGGERARGGGAGGAGGPGPGGLQPGQRVLYKQSIAQRARTMALYNPIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILATAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAIIGLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCEGDTECREYWPGPNFGITNFDNILFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFAKERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDRNAEEKSPLDVLKRAATKKSRNDLIHAEEGEDRFADLCAVGSPFARASLKSGKTESSSYFRRKEKMFRFFIRRMVKAQSFYWVVLCVVALNTLCVAMVHYNQPRRLTTTLYFAEFVFLGLFLTEMSLKMYGLGPRSYFRSSFNCFDFGVIVGSVFEVVWAAIKPGSSFGISVLRALRLLRIFKVTKYWSSLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQILTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAARQQNSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRFATTRHLRPDMKTHLDRPLVVELGRDGARGPVGGKARPEAAEAPEGVDPPRRHHRHRDKDKTPAAGDQDRAEAPKAESGEPGAREERPRPHRSHSKEAAGPPEARSERGRGPGPEGGRRHHRRGSPEEAAEREPRRHRAHRHQDPSKECAGAKGERRARHRGGPRAGPREAESGEEPARRHRARHKAQPAHEAVEKETTEKEATEKEAEIVEADKEKELRNHQPREPHCDLETSGTVTVGPMHTLPSTCLQKVEEQPEDADNQRNVTRMGSQPPDPNTIVHIPVMLTGPLGEATVVPSGNVDLESQAEGKKEVEADDVMRSGPRPIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEVVILVVIALSSIALAAEDPVRTDSPRNNALKYLDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQLFKGKFFYCTDESKELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVSTGEGWPMVLKHSVDATYEEQGPSPGYRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKVMSECSLEKNERACIDFAISAKPLTRYMPQNRQSFQYKTWTFVVSPPFEYFIMAMIALNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSMECVLKIIAFGVLNYFRDAWNVFDFVTVLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIALDDDTSINRHNNFRTFLQALMLLFRSATGEAWHEIMLSCLSNQACDEQANATECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPISNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISVVWANLPQKTLDLLVPPHKPDEMTVGKVYAALMIFDFYKQNKTTRDQMQQAPGGLSQMGPVSLFHPLKATLEQTQPAVLRGARVFLRQKSSTSLSNGGAIQNQESGIKESVSWGTQRTQDAPHEARPPLERGHSTEIPVGRSGALAVDVQMQSITRRGPDGEPQPGLESQGRAASMPRLAAETQPVTDASPMKRSISTLAQRPRGTHLCSTTPDRPPPSQASSHHHHHRCHRRRDRKQRSLEKGPSLSADMDGAPSSAVGPGLPPGEGPTGCRRERERRQERGRSQERRQPSSSSSEKQRFYSCDRFGGREPPKPKPSLSSHPTSPTAGQEPGPHPQGSGSVNGSPLLSTSGASTPGRGGRRQLPQTPLTPRPSITYKTANSSPIHFAGAQTSLPAFSPGRLSRGLSEHNALLQRDPLSQPLAPGSRIGSDPYLGQRLDSEASVHALPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSSGGRARHSYHHPDQDHWC 17A45C6D1E76B39D gbr12935 1-(2-(diphenylmethoxy)ethyl)-4-(3-phenylpropyl)piperazine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) lox5_human Polyunsaturated fatty acid 5-lipoxygenase ALOX5 LOG5 Arachidonate 5-lipoxygenase protein protein human Homo sapiens Human MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI DIP protein P09917 original sequence version: 164 36F38C0A9E86BB21 edn1_human Endothelin-1 Preproendothelin-1 EDN1 protein protein human Homo sapiens Human MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW E2DA0EB86755BC3D 4-damp 1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ednra_human Endothelin-1 receptor Endothelin receptor type A EDNRA ETA ETRA protein protein human Homo sapiens Human METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN DIP protein P25101 original sequence version: 113 207272D4A231404F 8-oh-dpat 7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) o16a_conge Omega-conotoxin GVIA SNX-124 Shaker peptide protein protein conge Conus geographus MKLTCVVIVAVLLLTACQLITADDSRGTQKHRALGSTTELSLSTRCKSPGSSCSPTSYNCCRSCNPYTKRCYG 51A8C8FA630F7175 dpcpx Dipropylcyclopentylxanthine/8-Cyclopentyl-1,3-dipropylxanthine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) il4_human Interleukin-4 IL4 B-cell stimulatory factor 1 Lymphocyte stimulatory factor 1 Binetrakin Pitrakinra protein protein human Homo sapiens Human MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS 8725BF64B34D45F7 p30990-pro_0000019524 Neurotensin NTS protein protein human Homo sapiens Human QLYENKPRRPYIL 151 163 4C8314644C411763 mibolerone 7α,17β)-17-hydroxy-7,17-dimethylestr-4-en-3-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) diclofenac 2-[(2,6-dichlorophenyl)amino]benzeneacetic acid small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p22466-pro_0000010449 Galanin GAL GAL1 GALN GLNN protein protein human Homo sapiens Human GWTLNSAGYLLGPHAVGNHRSFSDKNGLTS 33 62 D60B68719E8EE807 aces_human Acetylcholinesterase ACHE protein protein human Homo sapiens Human MRPPQCLLHTPSLASPLLLLLLWLLGGGVGAEGREDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPRDPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQDRCSDL B9AA84C77831C302 u50488 small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) calrl_human Calcitonin gene-related peptide type 1 receptor CALCRL CGRPR Calcitonin receptor-like receptor protein protein human Homo sapiens Human MEKKCTLNFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQAEGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSASYTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN DIP protein Q16602 original sequence version: 94 AF98E55E5454767C ccr3_human C-C chemokine receptor type 3 CCR3 CMKBR3 Eosinophil eotaxin receptor protein protein human Homo sapiens Human MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF E95DCD7A6C643874 bkrb1_human B1 bradykinin receptor BDKRB1 BRADYB1 protein protein human Homo sapiens Human MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRCGGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN B62B0690A7593077 (r)α-me-histamine histamine H 3-receptor agonist small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) prgr_human Progesterone receptor PGR NR3C3 Nuclear receptor subfamily 3 group C member 3 protein protein human Homo sapiens Human MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVMDFIHVPILPLNHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPCASSTPVAVGDFPDCAYPPDAEPKDDAYPLYSDFQPPALKIKEEEEGAEASARSPRSYLVAGANPAAFPDFPLGPPPPLPPRATPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGASGCLLPRDGLPSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVVRALDAVALPQPVGVPNESQALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK DIP protein P06401 original sequence version: 196 DIP protein P06401-1 original sequence version: 186 DIP protein P06401-1 original sequence version: 192 80452E54FF3A0454 serotonin 3-(2-aminoethyl)-1H-indol-5-ol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) q9uhf0-pro_0000033566 Neurokinin-B TAC3 NKNB ZNEUROK1 UNQ585/PRO1155 protein protein human Homo sapiens Human DMHDFFVGLM 81 90 E1FA7C62C9C9CAA1 acm3_human Muscarinic acetylcholine receptor M3 CHRM3 protein protein human Homo sapiens Human MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL DIP protein P20309 original sequence version: 117 5CB473C57B9526E9 protriptyline 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) tspo_human Translocator protein TSPO BZRP MBR Mitochondrial benzodiazepine receptor PKBS Peripheral-type benzodiazepine receptor protein protein human Homo sapiens Human MAPPWVPAMGFTLAPSLGCFVGSRFVHGEGLRWYAGLQKPSWHPPHWVLGPVWGTLYSAMGYGSYLVWKELGGFTEKAVVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLLLVSGAAAATTVAWYQVSPLAARLLYPYLAWLAFTTTLNYCVWRDNHGWRGGRRLPE 6DD741BF99AB89D9 il4ra_human Interleukin-4 receptor subunit alpha IL4R 582J2.1 IL4RA protein protein human Homo sapiens Human MGWLCSGLLFPVSCLVLLQVASSGNMKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQHLLLGVSVSCIVILAVCLLCYVSITKIKKEWWDQIPNPARSRLVAIIIQDAQGSQWEKRSRGQEPAKCPHWKNCLTKLLPCFLEHNMKRDEDPHKAAKEMPFQGSGKSAWCPVEISKTVLWPESISVVRCVELFEAPVECEEEEEVEEEKGSFCASPESSRDDFQEGREGIVARLTESLFLDLLGEENGGFCQQDMGESCLLPPSGSTSAHMPWDEFPSAGPKEAPPWGKEQPLHLEPSPPASPTQSPDNLTCTETPLVIAGNPAYRSFSNSLSQSPCPRELGPDPLLARHLEEVEPEMPCVPQLSEPTTVPQPEPETWEQILRRNVLQHGAAAAPVSAPTSGYQEFVHAVEQGGTQASAVVGLGPPGEAGYKAFSSLLASSAVSPEKCGFGASSGEEGYKPFQDLIPGCPGDPAPVPVPLFTFGLDREPPRSPQSSHLPSSSPEHLGLEPGEKVEDMPKPPLPQEQATDPLVDSLGSGIVYSALTCHLCGHLKQCHGQEDGGQTPVMASPCCGCCCGDRSSPPTTPLRAPDPSPGGVPLEASLCPASLAPSGISEKSKSSSSFHPAPGNAQSSSQTPKIVNFVSVGPTYMRVS 9F886DF5612297F8 adrb2_human Beta-2 adrenergic receptor Beta-2 adrenoreceptor ADRB2 ADRB2R B2AR protein protein human Homo sapiens Human MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL DIP protein P07550 original sequence version: 180 DIP protein P07550 original sequence version: 144 408C22731C6EDFBE p01019-pro_0000032458 Angiotensin-2 AGT SERPINA8 Serpin A8 protein protein human Homo sapiens Human DRVYIHPF 34 41 DDD761E04B42D40A af-dx 384 AFDX-384 small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) aofb_human Amine oxidase [flavin-containing] B MAOB Monoamine oxidase type B protein protein human Homo sapiens Human MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV 358D1025F5BCA604 lsd-lysergic acid diethylamide (8R)-9,10-didehydro-N,N-diethyl-6-methylergoline-8-carboxamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ssr SSR128129E small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) aofa_human Amine oxidase [flavin-containing] A MAOA Monoamine oxidase type A protein protein human Homo sapiens Human MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS 4270E346928AE832 ccl11_human Eotaxin C-C motif chemokine 11 Small-inducible cytokine A11 Eosinophil chemotactic protein CCL11 SCYA11 protein protein human Homo sapiens Human MKVSAALLWLLLIAAAFSPQGLAGPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQDSMKYLDQKSPTPKP DIP protein P51671 original sequence version: 145 B433C30FDA4C71A7 arachidonic acid (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) acm4_human Muscarinic acetylcholine receptor M4 CHRM4 protein protein human Homo sapiens Human MANFTPVNGSSGNQSVRLVTSSSHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKQSVKKPPPGEAAREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPATELSTTEATTPAMPAPPLQPRALNPASRWSKIQIVTKQTGNECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR DIP protein P08173 original sequence version: 142 9C1B05B359A64289 gr 113808 1-(2-methylsulfonylaminoethyl-4-piperidinyl)methyl-1-methyl-1H-indole-3-carboxylate small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ada2a_human Alpha-2A adrenergic receptor ADRA2A ADRA2R ADRAR Alpha-2 adrenergic receptor subtype C10 Alpha-2A adrenoreceptor protein protein human Homo sapiens Human MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTPAAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV DIP protein P08913 original sequence version: 171 585E576149BDB696 pyy_human Peptide YY PYY PYY-I Peptide tyrosine tyrosine protein protein human Homo sapiens Human MVFVRRPWPALTTVLLALLVCLGALVDAYPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRYGKRDGPDTLLSKTFFPDGEDRPVRSRSEGPDLW C166B73412E356B1 5ht7r_human 5-hydroxytryptamine receptor 7 HTR7 5-HT-X Serotonin receptor 7 protein protein human Homo sapiens Human MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD 1F62E985EADE1F23 methoctramine Methoctramine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) yohimbine 17α-hydroxy-yohimban-16α- carboxylic acid methyl ester small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) acm2_human Muscarinic acetylcholine receptor M2 CHRM2 protein protein human Homo sapiens Human MNNSTNSSNNSLALTSPYKTFEVVFIVLVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLIIGVFSMNLYTLYTVIGYWPLGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVKRTTKMAGMMIAAAWVLSFILWAPAILFWQFIVGVRTVEDGECYIQFFSNAAVTFGTAIAAFYLPVIIMTVLYWHISRASKSRIKKDKKEPVANQDPVSPSLVQGRIVKPNNNNMPSSDDGLEHNKIQNGKAPRDPVTENCVQGEEKESSNDSTSVSAVASNMRDDEITQDENTVSTSLGHSKDENSKQTCIRIGTKTPKSDSCTPTNTTVEVVGSSGQNGDEKQNIVARKIVKMTKQPAKKKPPPSREKKVTRTILAILLAFIITWAPYNVMVLINTFCAPCIPNTVWTIGYWLCYINSTINPACYALCNATFKKTFKHLLMCHYKNIGATR DIP protein P08172 original sequence version: 157 2FC2FD7748C22BEC rx-821002 RX 821002 small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) clorgyline N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-prop-2-yn-1-amine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) butaclamol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) npy2r_human Neuropeptide Y receptor type 2 NPY2R NPY-Y2 receptor protein protein human Homo sapiens Human MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVSVTFKAKKNLEVRKNSGPNDSFTEATNV 7D018C0169597BC7 drd1_human D(1A) dopamine receptor DRD1 Dopamine D1 receptor protein protein human Homo sapiens Human MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT 64E062D765D0DBA7 ab-meca AB-MECA small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) atenolol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) win 55212-2 (R)-(+)-[2,3-Dihydro-5-methyl- 3-(4-morpholinylmethyl)pyrrolo [1,2,3-de]-1,4-benzoxazin-6-yl]- 1-napthalenylmethanone small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) q13519-pro_0000008327 Nociceptin PNOC OFQ protein protein human Homo sapiens Human FGGFTGARKSARKLANQ 130 146 3F63A785F8768409 ccr5_human C-C chemokine receptor type 5 HIV-1 fusion coreceptor CHEMR13 CCR5 CMKBR5 protein protein human Homo sapiens Human MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL DIP protein P51681 original sequence version: 108 DIP protein P51681 original sequence version: 130 88ECE1F38E6D45A7 galr2_human Galanin receptor type 2 GALR2 GALNR2 protein protein human Homo sapiens Human MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA C2D2FCB93E53C47E 5ht2a_human 5-hydroxytryptamine receptor 2A HTR2A HTR2 Serotonin receptor 2A protein protein human Homo sapiens Human MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV EF8AAC0BC5379DA2 npc-567 D-Arg-[Hyp3-D-Phe7]-Bradykinin small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) triamcinolone (11β,16α)-9-fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) fgf2_human Fibroblast growth factor 2 Basic fibroblast growth factor FGF2 FGFB Heparin-binding growth factor 2 protein protein human Homo sapiens Human MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS DIP protein P09038 original sequence version: 169 DIP protein P09038 original sequence version: 129 EAE98552A39D5E19 cnr2_human Cannabinoid receptor 2 CNR2 CX5 CB2A CB2B protein protein human Homo sapiens Human MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC A7ECF68C16E7514B pk-11195 N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) andr_human Androgen receptor Dihydrotestosterone receptor Nuclear receptor subfamily 3 group C member 4 AR DHTR NR3C4 protein protein human Homo sapiens Human MEVQLGLGRVYPRPPSKTYRGAFQNLFQSVREVIQNPGPRHPEAASAAPPGASLLLLQQQQQQQQQQQQQQQQQQQQQQQETSPRQQQQQQGEDGSPQAHRRGPTGYLVLDEEQQPSQPQSALECHPERGCVPEPGAAVAASKGLPQQLPAPPDEDDSAAPSTLSLLGPTFPGLSSCSADLKDILSEASTMQLLQQQQQEAVSEGSSSGRAREASGAPTSSKDNYLGGTSTISDNAKELCKAVSVSMGLGVEALEHLSPGEQLRGDCMYAPLLGVPPAVRPTPCAPLAECKGSLLDDSAGKSTEDTAEYSPFKGGYTKGLEGESLGCSGSAAAGSSGTLELPSTLSLYKSGALDEAAAYQSRDYYNFPLALAGPPPPPPPPHPHARIKLENPLDYGSAWAAAAAQCRYGDLASLHGAGAAGPGSGSPSAAASSSWHTLFTAEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGGEAGAVAPYGYTRPPQGLAGQESDFTAPDVWYPGGMVSRVPYPSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPIDYYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEEGEASSTTSPTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHTQ DIP protein P10275 original sequence version: 220 DIP protein P10275-1 original sequence version: 213 DIP protein P10275 original sequence version: 216 DIP protein P10275 original sequence version: 143 DIP protein P10275 original sequence version: 174 DIP protein P10275 original sequence version: 169 DIP protein P10275 original sequence version: 188 DIP protein P10275-1 original sequence version: 188 DIP protein P10275 original sequence version: 196 DIP protein P10275 original sequence version: 217 DIP protein P10275-1 original sequence version: 217 DIP protein P10275-1 original sequence version: 207 A73432C55D39AE06 5ht1b_human 5-hydroxytryptamine receptor 1B HTR1B HTR1DB Serotonin receptor 1B Serotonin 1D beta receptor S12 protein protein human Homo sapiens Human MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTS CD874DC7EB44CF12 cgp 12177 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) il8_human Interleukin-8 Protein 3-10C T-cell chemotactic factor CXCL8 C-X-C motif chemokine 8 Chemokine (C-X-C motif) ligand 8 Emoctakin Granulocyte chemotactic protein 1 IL8 Monocyte-derived neutrophil chemotactic factor Monocyte-derived neutrophil-activating peptide Neutrophil-activating protein 1 protein protein human Homo sapiens Human MTSKLAVALLAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS DIP protein P10145 original sequence version: 161 15C649996E89319F aminopotentidine APT/aminopotentidine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) sc6a2_human Sodium-dependent noradrenaline transporter SLC6A2 NAT1 NET1 SLC6A5 Norepinephrine transporter Solute carrier family 6 member 2 protein protein human Homo sapiens Human MLLARMNPQVQPENNGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQRDIRQFQLQHWLAI BDC6DF31316907BB cimetidine 2-cyano-1-methyl-3-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) hrh1_human Histamine H1 receptor HRH1 protein protein human Homo sapiens Human MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKCETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLRPENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKLYCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSRTDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFKRILHIRS DIP protein P35367 original sequence version: 137 E5DB418A4C17A985 p01042-pro_0000006687 Lysyl-bradykinin KNG1 BDK KNG Alpha-2-thiol proteinase inhibitor Fitzgerald factor High molecular weight kininogen Williams-Fitzgerald-Flaujeac factor protein protein human Homo sapiens Human KRPPGFSPFR 380 389 33CB7075B9C86777 pyrilamine mepyramine -N',N'-dimethyl-N-(p-methoxybenzyl)-N-(2-pyridyl)ethylenediamine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ns398 N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p20366-pro_0000033534 Neurokinin A TAC1 NKA NKNA TAC2 PPT protein protein human Homo sapiens Human HKTDSFVGLM 98 107 8A6B4062C9D5BAB1 galr1_human Galanin receptor type 1 GALR1 GALNR GALNR1 protein protein human Homo sapiens Human MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV A0664227157B3410 fluormone- es2 fluormone- es2 -a fluorescent estrogen -identity unknown small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ndga_dihydronorguaiaretic acid 4,4'-(2,3-dimethylbutane-1,4-diyl)dibenzene-1,2-diol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) hrh3_human Histamine H3 receptor HRH3 GPCR97 G-protein coupled receptor 97 protein protein human Homo sapiens Human MERAPPDGPLNASGALAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSAFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMLLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGAREAAGPEPPPEAQPSPPPPPGCWGCWQKGHGEAMPLHRYGVGEAAVGAEAGEATLGGGGGGGSVASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSFTQRFRLSRDRKVAKSLAVIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHHSFRRAFTKLLCPQKLKIQPHSSLEHCWK 2ACF7440FBE95B6C oprk_human Kappa-type opioid receptor OPRK1 OPRK protein protein human Homo sapiens Human MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV 3DA6E9F90FB48825 paroxetine (3S,4R)-3-[(2H-1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p01042-pro_0000006688 Bradykinin KNG1 BDK KNG Alpha-2-thiol proteinase inhibitor Fitzgerald factor High molecular weight kininogen Williams-Fitzgerald-Flaujeac factor protein protein human Homo sapiens Human RPPGFSPFR 381 389 3393D775B9C86777 ib-meca IB-MECA small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) vipr1_human Vasoactive intestinal polypeptide receptor 1 VIPR1 Pituitary adenylate cyclase-activating polypeptide type II receptor VPAC1 protein protein human Homo sapiens Human MRPPSPLPARWLCVLAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIGCSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRSSSFQAEVSLV DAA40CF5BEC47D7D p11362-14 Fibroblast growth factor receptor 1 I H3 FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR Basic fibroblast growth factor receptor 1 Fms-like tyrosine kinase 2 N-sam Proto-oncogene c-Fgr protein protein human Homo sapiens Human MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR DIP protein P11362-14 original sequence version: 189 BFA81F8DADF4C9F4 cnr1_human Cannabinoid receptor 1 CNR1 CNR CANN6 protein protein human Homo sapiens Human MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL DIP protein P21554 original sequence version: 162 1D2E49061D12ABF2 calca_human Calcitonin gene-related peptide 1 CALCA CALC1 Calcitonin gene-related peptide I Alpha-type CGRP protein protein human Homo sapiens Human MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA A003A1069260D9B8 acm1_human Muscarinic acetylcholine receptor M1 CHRM1 protein protein human Homo sapiens Human MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVNNYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLISFDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYIQFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSSSERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEVVIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKEKKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYALCNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC 567C20F63541C8D0 bkrb2_human B2 bradykinin receptor BDKRB2 BKR2 protein protein human Homo sapiens Human MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ 066940ED3D18BB66 p01210-pro_0000008243 Met-enkephalin PENK protein protein human Homo sapiens Human YGGFM 100 104 6699C8786B300000 oprx_human Nociceptin receptor OPRL1 OOR ORL1 Orphanin FQ receptor Kappa-type 3 opioid receptor protein protein human Homo sapiens Human MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALACKTSETVPRPA 613700C0B4D093BA neca N-ETHYL-5'-CARBOXAMIDO ADENOSINE small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) oprm_human Mu-type opioid receptor OPRM1 MOR1 Mu opioid receptor Mu opiate receptor protein protein human Homo sapiens Human MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP 1DABEBEC9AFF6F66 kynuramine 3-amino-1-(2- aminophenyl)propan-1-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) dpdpe D-Penicillamine(2,5)-enkephalin small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) nk3r_human Neuromedin-K receptor TACR3 NK3R TAC3R NK-3 receptor Neurokinin B receptor Tachykinin receptor 3 protein protein human Homo sapiens Human MATLPAAETWIDGGGGVGADAVNLTASLAAGAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELKTTRFHPNRQSSMYTVTRMESMTVVFDPNDADTTRSSRKKRATPRDPSFNGCSRRNSKSASATSSFISSPYTSVDEYS 98E88D4BC9DBD315 sc6a3_human Sodium-dependent dopamine transporter SLC6A3 DAT1 Solute carrier family 6 member 3 protein protein human Homo sapiens Human MSKSKCSVGLMSSVVAPAKEPNAVGPKEVELILVKEQNGVQLTSSTLTNPRQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLHRHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAYAIAPEKDRELVDRGEVRQFTLRHWLKV DIP protein Q01959 original sequence version: 150 DIP protein Q01959 original sequence version: 119 CD95009B6BA93108 acm5_human Muscarinic acetylcholine receptor M5 CHRM5 protein protein human Homo sapiens Human MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAEKRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQLTTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPNYLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNPNPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLGYWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP EE846186F645DD9B adrb1_human Beta-1 adrenergic receptor Beta-1 adrenoreceptor ADRB1 ADRB1R B1AR protein protein human Homo sapiens Human MGAGVLVLGASEPGNLSSAAPLPDGAATAARLLVPASPPASLLPPASESPEPLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAARRRHATHGDRPRASGCLARPGPPPSPGAASDDDDDDVVGATPPARLLEPWAGCNGGAAADSDSSLDEPCRPGFASESKV DIP protein P08588 original sequence version: 119 DIP protein P08588 original sequence version: 133 0950F2684E4721B8 5ht1a_human 5-hydroxytryptamine receptor 1A HTR1A ADRB2RL1 ADRBRL1 G-21 Serotonin receptor 1A protein protein human Homo sapiens Human MDVLSPGQGNNTTSPPAPFETGGNTTGISDVTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ 762664FCF62CFD8F fgfr2_human Fibroblast growth factor receptor 2 FGFR2 BEK KSAM Keratinocyte growth factor receptor KGFR K-sam protein protein human Homo sapiens Human MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEVRCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT 6CD5001C960ED82F ici 118551 (2R,3S)-1-[(7-methyl-2,3-dihydro-1H-inden-4-yl)oxy]-3-(propan-2-ylamino)butan-2-ol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) nos2_human Nitric oxide synthase, inducible NOS2 NOS2A Hepatocyte NOS Inducible NO synthase NOS type II Peptidyl-cysteine S-nitrosylase NOS2 protein protein human Homo sapiens Human MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPLVETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLEMSAL DIP protein P35228 original sequence version: 140 47671E5385CB3A52 neostigmine 3-[(dimethylcarbamoyl)oxy]-N,N,N-trimethylanilinium small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) arginine (2S)-2-amino-5-(carbamimidamido)pentanoic acid small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) acetyl-beta-methyl-thiocholine acetyl-beta-methyl-thiocholine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) npy1r_human Neuropeptide Y receptor type 1 NPY1R NPYR NPYY1 protein protein human Homo sapiens Human MNSTLFSQVENHSVHSNFSEKNAQLLAFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLKQASPVAFKKINNNDDNEKI 582B0DDB04490316 l-nmma N(omega)-methyl-L-arginine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) imipramine 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p01017-pro_0000032443 Angiotensin-2 AGT SERPINA8 Serpin A8 protein protein bovin Bos taurus (Bovine) Bovine DRVYVHPF 25 32 DDD761F2DB42D40A 5ht6r_human 5-hydroxytryptamine receptor 6 Serotonin receptor 6 HTR6 protein protein human Homo sapiens Human MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN C888F47650C1D2EF 5ht4r_human 5-hydroxytryptamine receptor 4 HTR4 Serotonin receptor 4 protein protein human Homo sapiens Human MDKLDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRDAVECGGQWESQCHPPATSPLVAAQPSDT 7FCFEC60E7BDF560 p06307-pro_0000010542 Cholecystokinin-8 CCK protein protein human Homo sapiens Human DYMGWMDF 96 103 DDCAA68378768B5A pgh2_human Prostaglandin G/H synthase 2 PTGS2 COX2 Cyclooxygenase-2 PHS II Prostaglandin H2 synthase 2 Prostaglandin-endoperoxide synthase 2 protein protein human Homo sapiens Human MLARALLLCAVLALSHTANPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYILTHFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRALPPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKTDHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAEMIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLPDTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASIDQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKPRPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNVKGCPFTSFSVPDPELIKTVTINASSSRSGLDDINPTVLLKERSTEL DIP protein P35354 original sequence version: 161 72FBD699F6128519 cxcr2_human C-X-C chemokine receptor type 2 CXCR2 IL8RB CDw128b GRO/MGSA receptor High affinity interleukin-8 receptor B IL-8 receptor type 2 protein protein human Homo sapiens Human MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL DIP protein P25025 original sequence version: 138 564F04A8BCC0A197 ednrb_human Endothelin receptor type B EDNRB ETRB Endothelin receptor non-selective type protein protein human Homo sapiens Human MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS CD4F96CF92C7C51E cckar_human Cholecystokinin receptor type A CCKAR CCKRA Cholecystokinin-1 receptor protein protein human Homo sapiens Human MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ A6E8FABDA805E610 aa1r_human Adenosine receptor A1 ADORA1 protein protein human Homo sapiens Human MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD 1B555893BCDEC9A6 p20366-pro_0000033530 Substance P TAC1 NKA NKNA TAC2 PPT protein protein human Homo sapiens Human RPKPQQFFGLM 58 68 3E757FE3C9D6C6C7 p01282-pro_0000011460 Vasoactive intestinal peptide VIP protein protein human Homo sapiens Human HSDAVFTDNYTRLRKQMAVKKYLNSILN 125 152 EF313FB573FF6F3F p01019-pro_0000032459 Angiotensin-3 AGT SERPINA8 Serpin A8 protein protein human Homo sapiens Human RVYIHPF 35 41 69D761E04B42D460 agtr2_human Type-2 angiotensin II receptor AGTR2 Angiotensin II type-2 receptor protein protein human Homo sapiens Human MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS FDD7D4E6F9B43E60 nk2r_human Substance-K receptor TACR2 NK2R NKNAR TAC2R NK-2 receptor Neurokinin A receptor Tachykinin receptor 2 protein protein human Homo sapiens Human MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMAGDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI 20AD618EF74263A7 gbr12909-vanoxerine 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p01303-pro_0000025321 Neuropeptide Y NPY protein protein human Homo sapiens Human YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY 29 64 0D06921202CD0DD6 u69593 N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl)-1-oxaspiro[4.5]dec-8-yl]acetamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) r_5020_promegestone (8S,13S,14S,17S)-13,17-dimethyl-17-propanoyl-1,2,6,7,8,11,12,14,15, 16-decahydrocyclopenta[a]phenanthren-3-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) 5ht5a_human 5-hydroxytryptamine receptor 5A HTR5A Serotonin receptor 5A protein protein human Homo sapiens Human MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH 92F8A78C69169790 ntr1_human Neurotensin receptor type 1 NTSR1 NTRR High-affinity levocabastine-insensitive neurotensin receptor NTRH protein protein human Homo sapiens Human MRLNSSAPGTPGTPAADPFQRAQAGLEEALLAPGFGNASGNASERVLAAPSSELDVNTDIYSKVLVTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAVPMLFTMGEQNRSADGQHAGGLVCTPTIHTATVKVVIQVNTFMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHGVRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINPILYNLVSANFRHIFLATLACLCPVWRRRRKRPAFSRKADSVSSNHTLSSNATRETLY DIP protein P30989 original sequence version: 136 471AD1C49D29C2C8 dexamethasone (8S,9R,10S,11S,13S,14S,16R,17R)-9- Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16- trimethyl-6,7,8,9,10,11,12,13,14,15,16,17- dodecahydro-3H-cyclopenta[a]phenanthren-3-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) agtr1_human Type-1 angiotensin II receptor AGTR1 AGTR1A AGTR1B AT2R1 AT2R1B AT1AR AT1BR Angiotensin II type-1 receptor protein protein human Homo sapiens Human MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSTKKPAPCFEVE 35FC856F53E911A6 drd2_human D(2) dopamine receptor DRD2 Dopamine D2 receptor protein protein human Homo sapiens Human MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC 9BF8EA36C988A2E2 gasr_human Gastrin/cholecystokinin type B receptor CCKBR CCKRB Cholecystokinin-2 receptor protein protein human Homo sapiens Human MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGPRVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQACLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG BAEEFAD4C1F85915 sc6a4_human Sodium-dependent serotonin transporter SLC6A4 HTT SERT 5HT transporter Solute carrier family 6 member 4 protein protein human Homo sapiens Human METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNYFSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEYATGPAVLTVALIEAVAVSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFLLFIICSFLMSPPQLRLFQYNYPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITPETPTEIPCGDIRLNAV 0EB535B0A579BDA2 devazepide N-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1, 4-benzodiazepin-3-yl]-1H-indole-2-carboxamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) sch_23390 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) egf_human Pro-epidermal growth factor EGF protein protein human Homo sapiens Human MLLTLIILLPVVSKFSFVSLSAPQHWSCPEGTLAGNGNSTCVGPAPFLIFSHGNSIFRIDTEGTNYEQLVVDAGVSVIMDFHYNEKRIYWVDLERQLLQRVFLNGSRQERVCNIEKNVSGMAINWINEEVIWSNQQEGIITVTDMKGNNSHILLSALKYPANVAVDPVERFIFWSSEVAGSLYRADLDGVGVKALLETSEKITAVSLDVLDKRLFWIQYNREGSNSLICSCDYDGGSVHISKHPTQHNLFAMSLFGDRIFYSTWKMKTIWIANKHTGKDMVRINLHSSFVPLGELKVVHPLAQPKAEDDTWEPEQKLCKLRKGNCSSTVCGQDLQSHLCMCAEGYALSRDRKYCEDVNECAFWNHGCTLGCKNTPGSYYCTCPVGFVLLPDGKRCHQLVSCPRNVSECSHDCVLTSEGPLCFCPEGSVLERDGKTCSGCSSPDNGGCSQLCVPLSPVSWECDCFPGYDLQLDEKSCAASGPQPFLLFANSQDIRHMHFDGTDYGTLLSQQMGMVYALDHDPVENKIYFAHTALKWIERANMDGSQRERLIEEGVDVPEGLAVDWIGRRFYWTDRGKSLIGRSDLNGKRSKIITKENISQPRGIAVHPMAKRLFWTDTGINPRIESSSLQGLGRLVIASSDLIWPSGITIDFLTDKLYWCDAKQSVIEMANLDGSKRRRLTQNDVGHPFAVAVFEDYVWFSDWAMPSVMRVNKRTGKDRVRLQGSMLKPSSLVVVHPLAKPGADPCLYQNGGCEHICKKRLGTAWCSCREGFMKASDGKTCLALDGHQLLAGGEVDLKNQVTPLDILSKTRVSEDNITESQHMLVAEIMVSDQDDCAPVGCSMYARCISEGEDATCQCLKGFAGDGKLCSDIDECEMGVPVCPPASSKCINTEGGYVCRCSEGYQGDGIHCLDIDECQLGEHSCGENASCTNTEGGYTCMCAGRLSEPGLICPDSTPPPHLREDDHHYSVRNSDSECPLSHDGYCLHDGVCMYIEALDKYACNCVVGYIGERCQYRDLKWWELRHAGHGQQQKVIVVAVCVVVLVMLLLLSLWGAHYYRTQKLLSKNPKNPYEESSRDVRSRRPADTEDGMSSCPQPWFVVIKEHQDLKNGGQPVAGEDGQAADGSMQPTSWRQEPQLCGMGTEQGCWIPVSSDKGSCPQVMERSFHMPSYGTQTLEGGVEKPHSLLSANPLWQQRALDPPHQMELTQ DIP protein P01133 original sequence version: 89 DIP protein P01133 original sequence version: 100 DIP protein P01133-1 original sequence version: 136 DIP protein P01133-1 original sequence version: 181 3C787F1D405CFAF1 hrh2_human Histamine H2 receptor HRH2 Gastric receptor I protein protein human Homo sapiens Human MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR 9835AE2BA60B9B0F pgh1_human Prostaglandin G/H synthase 1 PTGS1 COX1 Cyclooxygenase-1 Prostaglandin H2 synthase 1 Prostaglandin-endoperoxide synthase 1 protein protein human Homo sapiens Human MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 1F4F734BCD00346D aa2ar_human Adenosine receptor A2a ADORA2A ADORA2 protein protein human Homo sapiens Human MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS 9438E9D64A6BE61B oprd_human Delta-type opioid receptor OPRD1 OPRD protein protein human Homo sapiens Human MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA 9D483FC39BA2BAE4 egfr_human Epidermal growth factor receptor ERBB1 EGFR Receptor tyrosine-protein kinase erbB-1 Proto-oncogene c-ErbB-1 ERBB HER1 protein protein human Homo sapiens Human MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTEDSIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLNTVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRVAPQSSEFIGA DIP protein P00533 original sequence version: 213 DIP protein P00533 original sequence version: 214 DIP protein P00533 original sequence version: 119 DIP protein P00533 original sequence version: 207 DIP protein P00533 original sequence version: 132 DIP protein P00533-1 original sequence version: 197 DIP protein P00533 original sequence version: 163 DIP protein P00533-1 original sequence version: 159 DIP protein P00533 original sequence version: 184 DIP protein P00533-1 original sequence version: 174 DIP protein P00533-1 original sequence version: 191 DIP protein P00533 original sequence version: 218 DIP protein P00533 original sequence version: 221 DIP protein P00533-1 original sequence version: 221 DIP protein P00533 original sequence version: 226 DIP protein P00533 original sequence version: 166 DIP protein P00533-1 original sequence version: 166 DIP protein P00533 original sequence version: 194 DIP protein P00533-1 original sequence version: 194 DIP protein P00533-1 original sequence version: 224 DIP protein P00533 original sequence version: 189 DIP protein P00533-1 original sequence version: 207 DIP protein P00533 original sequence version: 177 DIP protein P00533 original sequence version: 168 D8A2A50B4EFB6ED2 iodocyanopindolol/cyp -4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-3-iodo-1H-indole-2-carbonitrile small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p13236-pro_0000005165 MIP-1-beta(3-69) CCL4 LAG1 MIP1B SCYA4 G-26 T-lymphocyte-secreted protein HC21 Lymphocyte activation gene 1 protein MIP-1-beta(1-69) Macrophage inflammatory protein 1-beta PAT 744 Protein H400 SIS-gamma Small-inducible cytokine A4 T-cell activation protein 2 protein protein human Homo sapiens Human MGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLELN 26 92 D355DCCEF81FDAE9 aa3r_human Adenosine receptor A3 ADORA3 UNQ1931/PRO4406 protein protein human Homo sapiens Human MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE 690E67986130FC28 spiperone 8-[4-(4-fluorophenyl)-4-oxo-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) ketanserin 3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}quinazoline-2,4(1H,3H)-dione small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) 5ht2c_human 5-hydroxytryptamine receptor 2C 5-hydroxytryptamine receptor 1C Serotonin receptor 2C HTR2C HTR1C protein protein human Homo sapiens Human MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV 9E76B3FFD3E09C93 gcr_human Glucocorticoid receptor Nuclear receptor subfamily 3 group C member 1 NR3C1 GRL protein protein human Homo sapiens Human MDSKESLTPGREENPSSVLAQERGDVMDFYKTLRGGATVKVSASSPSLAVASQSDSKQRRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLKLLEESIANLNRSTSVPENPKSSASTAVSAAPTEKEFPKTHSDVSSEQQHLKGQTGTNGGNVKLYTTDQSTFDILQDLEFSSGSPGKETNESPWRSDLLIDENCLLSPLAGEDDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSPSNVTLPQVKTEKEDFIELCTPGVIKQEKLGTVYCQASFPGANIIGNKMSAISVHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQK C5C90C9A5DD16AAB mesulergine N'-[(8α)-1,6-dimethylergolin-8-yl)-N,N-dimethylsulfamide small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) esr1_human Estrogen receptor ESR1 ESR NR3A1 Estradiol receptor ER-alpha Nuclear receptor subfamily 3 group A member 1 protein protein human Homo sapiens Human MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV DIP protein P03372 original sequence version: 214 DIP protein P03372 original sequence version: 139 DIP protein P03372 original sequence version: 167 5455C57AB0CCCAA7 pirenzepine/gastrozepin 11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) nisoxetine (RS)-3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) p01185-pro_0000020515 Arg-vasopressin AVP ARVP VP AVP-NPII protein protein human Homo sapiens Human CYFQNCPRG 20 28 17EB176EB456D9DB deprenyl/selegiline N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) nk1r_human Substance-P receptor TACR1 NK1R TAC1R NK-1 receptor Tachykinin receptor 1 protein protein human Homo sapiens Human MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS 2AFFD3F61B1A3041 v1ar_human Vasopressin V1a receptor AVPR1A AVPR1 AVPR V1a Antidiuretic hormone receptor 1a Vascular/hepatic-type arginine vasopressin receptor protein protein human Homo sapiens Human MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST 477D4260EC826561 fgfr1-fgf2 1 62 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 86 unspecified role unspecified role bait bait c_terminus fc-igg tag fc-igg tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range ig_like-d1_d2_d3_extracellular_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain direct interaction direct interaction no figure fgfr1-fgf2-3 1 86 unspecified role unspecified role bait bait ig_like-d1_d2_d3_extracellular_domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain c_terminus fc-igg tag fc-igg tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range mouse-nso NSO-mouse myeloma subclone of NS-1 ns0 NS0 Mouse Myeloma subclone of NS-1 http://www.hpacultures.org.uk/products/celllines/generalcell/detail.jsp?refId=85110503&collection=ecacc_gc from ecacc 62 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 62 competitor competitor competitor prey prey 36 inhibitor inhibitor prey prey chemical synthesis Chemical synthesis (Chemical synthesis) direct interaction direct interaction no figure-2 A 10- to 100-fold molar excess of unlabeled FGF2 or anti-FGFR1 Fab (αFGFR1) inhibited 125I-FGF2 binding completely. fgfr2-ssr 2 102 unspecified role unspecified role neutral component neutral component purified purified ig_like_d2_and_ d3_extracellular region required to bind necessary binding region required to bind certain certain sequence position certain certain certain sequence position certain mouse-nso NSO-mouse myeloma subclone of NS-1 ns0 NS0 Mouse Myeloma subclone of NS-1 http://www.hpacultures.org.uk/products/celllines/generalcell/detail.jsp?refId=85110503&collection=ecacc_gc from ecacc 36 unspecified role unspecified role neutral component neutral component direct interaction direct interaction 3A/B adora1-dpcpx 1 12 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 119 unspecified role unspecified role bait bait physical association physical association Table S2-1 adora1-dpcpx-2 1 12 competitor competitor competitor prey prey 119 unspecified role unspecified role bait bait 12 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-2 adora1-dpcpx-3 1 141 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-3 adora2a-cgs_21680-1 1 93 competitor competitor competitor prey prey 141 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-4 adora1-dpcpx-4 1 53 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 146 unspecified role unspecified role bait bait physical association physical association Table S2-5 adora3-ab_meca-1 1 84 competitor competitor competitor prey prey 146 unspecified role unspecified role bait bait 53 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-6 adora1-dpcpx-5 1 48 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 42 unspecified role unspecified role bait bait physical association physical association Table S2-7 adra2a-rx_821002-1 1 48 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 42 unspecified role unspecified role bait bait 46 competitor competitor competitor prey prey physical association physical association Table S2-8 adora2a-cgs_21680-2 1 67 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 100 unspecified role unspecified role bait bait physical association physical association Table S2-9 adrb1-atenolol 1 54 competitor competitor competitor prey prey 100 unspecified role unspecified role bait bait 67 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-10 adrb1-cgp_12177 1 67 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 31 unspecified role unspecified role bait bait physical association physical association Table S2-11 adrb2-cgp_12177-1 1 103 competitor competitor competitor prey prey 31 unspecified role unspecified role bait bait 67 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-12 cgs_21680-agt 1 32 unspecified role unspecified role prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:40:38 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'asp1n-methyl-glycine' P01019-PRO_0000032458:p.Phe8Ile mutation mutation certain certain sequence position certain certain certain sequence position certain F I Wed May 02 18:50:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe8ile' Tue Jun 30 19:57:57 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe8Ile' region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 132 unspecified role unspecified role bait bait physical association physical association Table S2-13 agtr1-agt-7 1 32 unspecified role unspecified role prey prey P01019-PRO_0000032458:p.Phe8Ile mutation mutation certain certain sequence position certain certain certain sequence position certain F I Wed May 02 17:25:38 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe8ile' Tue Jun 30 17:58:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe8Ile' undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:40:58 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'asp1n-methyl-glycine' region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 132 unspecified role unspecified role bait bait 111 competitor competitor competitor prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:41:11 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'asp1n-methylglycine' P01017-PRO_0000032443:p.Phe8Ala mutation mutation certain certain sequence position certain certain certain sequence position certain F A Wed May 02 15:43:24 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe8ala' Tue Jun 30 18:17:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe8Ala' physical association physical association Table S2-14 the editor will only let me enter the mutations as nos 1 +8 - not the numbers corresponding to the full length protein. agtr1-agt-8 1 111 competitor competitor competitor prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:38:21 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'asp1n-methylglycine' P01017-PRO_0000032443:p.Phe8Ala mutation mutation certain certain sequence position certain certain certain sequence position certain F A Wed May 02 16:01:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe8ala' Tue Jun 30 18:45:31 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe8Ala' 123 unspecified role unspecified role bait bait 122 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-16 agtr2-agt 1 123 unspecified role unspecified role bait bait 122 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-15 the editor will only let me enter the mutations as nos 1 +8 - not the numbers corresponding to the full length protein. adora2a-cgs_21680-3 1 64 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role bait bait physical association physical association Table S2-17 tspo-pk_11195-1 1 64 competitor competitor competitor prey prey 64 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 29 unspecified role unspecified role bait bait physical association physical association Table S2-18 adrb2-cgp_12177-2 1 73 unspecified role unspecified role prey prey delta_10arg_kallidin sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 22 unspecified role unspecified role bait bait physical association physical association Table S2-19 bdkrb1-kng1-1 1 83 competitor competitor competitor prey prey P01042-PRO_0000006688:p.Phe8Leu mutation mutation certain certain sequence position certain certain certain sequence position certain F L Wed May 02 16:48:23 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'phe8leu' Tue Jun 30 19:41:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Phe8Leu' delta_9arg sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 73 unspecified role unspecified role prey prey delta_10arg_kallidin sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 22 unspecified role unspecified role bait bait physical association physical association Table S2-20 bdkrb1-kng1-2 1 83 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 90 unspecified role unspecified role bait bait physical association physical association Table S2-21 bdkrb2-kng1-1 1 60 competitor competitor competitor prey prey 90 unspecified role unspecified role bait bait 83 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-22 bdkrb2-kng1-2 1 88 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 20 unspecified role unspecified role bait bait physical association physical association Table S2-23 calcrl-calca-1 1 88 competitor competitor competitor prey prey 88 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 20 unspecified role unspecified role bait bait physical association physical association Table S2-24 calcrl-calca-2 1 55 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 55 competitor competitor competitor prey prey 87 unspecified role unspecified role bait bait physical association physical association Table S2-25 cnr1-win_55212_2 1 63 unspecified role unspecified role bait bait 55 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 55 competitor competitor competitor prey prey physical association physical association Table S2-27 cnr1-win_55212_2-1 1 55 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 87 unspecified role unspecified role bait bait physical association physical association Table S2-26 cnr2-win_55212_2 1 55 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 63 unspecified role unspecified role bait bait physical association physical association Table S2-28 cnr2-win_55212_2-1 1 136 competitor competitor competitor prey prey 136 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 118 unspecified role unspecified role bait bait physical association physical association Table S2-29 cckar-devazepide 1 118 unspecified role unspecified role bait bait 136 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-30 cckar-devazepide-1 1 114 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 134 unspecified role unspecified role bait bait 114 competitor competitor competitor prey prey physical association physical association Table S2-31 cckbr-cck 1 114 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 134 unspecified role unspecified role bait bait physical association physical association Table S2-32 cckbr-cck-1 1 137 competitor competitor competitor prey prey 52 unspecified role unspecified role bait bait 137 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-33 drd1-sch 1 137 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 52 unspecified role unspecified role bait bait physical association physical association Table S2-34 drd1-sch-1 1 147 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 50 competitor competitor competitor prey prey 133 unspecified role unspecified role bait bait physical association physical association Table S2-35 drd2-butaclamol 1 147 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 133 unspecified role unspecified role bait bait physical association physical association Table S2-36 drd2-butaclamol-1 1 7 competitor competitor competitor prey prey 7 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 9 unspecified role unspecified role bait bait physical association physical association Table S2-37 ednra-edn1 1 9 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-38 ednra-edn1-1 1 7 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 117 unspecified role unspecified role bait bait 7 competitor competitor competitor prey prey physical association physical association Table S2-39 ednrb-edn1 1 117 unspecified role unspecified role bait bait 7 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-40 ednrb-edn1-1 1 17 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 77 unspecified role unspecified role bait bait 17 competitor competitor competitor prey prey physical association physical association Table S2-41 galr1-gal 1 77 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-42 galr1-gal-1 1 17 competitor competitor competitor prey prey 58 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-43 galr2-gal 1 58 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-44 galr2-gal-1 1 138 competitor competitor competitor prey prey 143 unspecified role unspecified role bait bait 138 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-45 egfr-egf-9 1 138 competitor competitor competitor prey prey 143 unspecified role unspecified role bait bait 138 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-46 egfr-egf-9 1 13 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 13 competitor competitor competitor prey prey 30 unspecified role unspecified role bait bait physical association physical association Table S2-47 il4r-il4-4 1 30 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-48 il4r-il4-5 1 68 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 68 competitor competitor competitor prey prey 116 unspecified role unspecified role bait bait physical association physical association Table S2-49 cxcr2-il8 1 116 unspecified role unspecified role bait bait 68 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-50 cxcr2-il8-1 1 38 competitor competitor competitor prey prey 38 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait physical association physical association Table S2-51 ccr5-ccl11 1 57 unspecified role unspecified role bait bait 145 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 145 competitor competitor competitor prey prey physical association physical association Table S2-53 cxcr3-ccl11-1 1 21 unspecified role unspecified role bait bait 38 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-52 ccr5-ccl4 1 72 unspecified role unspecified role bait bait 74 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 74 competitor competitor competitor prey prey physical association physical association Table S2-55 ccr5-ccl4-1 1 145 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 57 unspecified role unspecified role bait bait physical association physical association Table S2-54 hrh1-pyrilamine 1 139 unspecified role unspecified role bait bait 69 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 71 competitor competitor competitor prey prey physical association physical association Table S2-57 hrh1-pyrilamine-1 1 72 unspecified role unspecified role bait bait 74 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-56 hrh2-aminopotentidin 1 69 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 139 unspecified role unspecified role bait bait physical association physical association Table S2-58 hrh2-aminopotentid-1 1 23 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 23 competitor competitor competitor prey prey 80 unspecified role unspecified role bait bait physical association physical association Table S2-59 hrh3-_r___me_histami 1 23 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 80 unspecified role unspecified role bait bait physical association physical association Table S2-60 hrh3-_r___me_hista-1 1 153 competitor competitor competitor prey prey 153 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 89 unspecified role unspecified role bait bait physical association physical association Table S2-61 chrm1-pirenzepine_ga 1 89 unspecified role unspecified role bait bait 153 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-62 chrm1-pirenzepine_-1 1 45 competitor competitor competitor prey prey 47 unspecified role unspecified role bait bait 33 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-63 chrm2-af_dx_384 1 33 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 47 unspecified role unspecified role bait bait physical association physical association Table S2-64 chrm2-af_dx_384-1 1 8 competitor competitor competitor prey prey 8 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role bait bait physical association physical association Table S2-65 chrm3-4_damp 1 8 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role bait bait physical association physical association Table S2-66 chrm3-4_damp-1 1 40 unspecified role unspecified role bait bait 8 competitor competitor competitor prey prey 8 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-67 chrm4-4_damp 1 8 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 40 unspecified role unspecified role bait bait physical association physical association Table S2-68 chrm4-4_damp-1 1 120 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined gly9sar megly methylated glycine MeGly certain certain sequence position certain certain certain sequence position certain met11_oxidation meto2 L-methionine sulfone (2S)-2-amino-4-(methylsulfonyl)butanoic acid L-methionine S,S-dioxide L-methionine sulfone MOD_RES Methionine sulfone S,S-dioxymethionine Dioxidation MetO2 MethionylSulphone Oxidation of Methionine (to Sulphone) dihydroxy suphonem certain certain sequence position certain certain certain sequence position certain 157 unspecified role unspecified role bait bait physical association physical association Table S2-71 chrm5-4_damp 1 99 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-70 tacr1-tac1 1 120 unspecified role unspecified role prey prey met11_oxidation meto2 L-methionine sulfone (2S)-2-amino-4-(methylsulfonyl)butanoic acid L-methionine S,S-dioxide L-methionine sulfone MOD_RES Methionine sulfone S,S-dioxymethionine Dioxidation MetO2 MethionylSulphone Oxidation of Methionine (to Sulphone) dihydroxy suphonem certain certain sequence position certain certain certain sequence position certain region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined gly9sar megly methylated glycine MeGly certain certain sequence position certain certain certain sequence position certain 157 unspecified role unspecified role bait bait 120 competitor competitor competitor prey prey gly9sar megly methylated glycine MeGly certain certain sequence position certain certain certain sequence position certain met11_oxidation meto2 L-methionine sulfone (2S)-2-amino-4-(methylsulfonyl)butanoic acid L-methionine S,S-dioxide L-methionine sulfone MOD_RES Methionine sulfone S,S-dioxymethionine Dioxidation MetO2 MethionylSulphone Oxidation of Methionine (to Sulphone) dihydroxy suphonem certain certain sequence position certain certain certain sequence position certain physical association physical association Table S2-72 tacr1-tac1-1 1 76 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 124 unspecified role unspecified role bait bait physical association physical association Table S2-73 tacr2-tac1 1 76 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 124 unspecified role unspecified role bait bait 76 competitor competitor competitor prey prey leu9 nme1leu N-methyl-L-leucine (S)-2-methylamino-4-methylpentanoic acid 2-(methylamino)-4-methyl-valeric acid MOD_RES N-methylleucine N-methyl-L-leucine N-methylated L-leucine N-methylleucine Methyl Methylation NMe1Leu certain certain sequence position certain certain certain sequence position certain P20366-PRO_0000033534:p.Ser5Lys mutation mutation certain certain sequence position certain certain certain sequence position certain S K Wed May 02 15:02:57 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser5lys' Tue Jun 30 19:54:38 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ser5Lys' P20366-PRO_0000033534:p.Met10Xaa mutation mutation certain certain sequence position certain certain certain sequence position certain M X Methione 10 was mutated to unconventional amino acid norleucine (nle). Fri Jul 22 11:05:34 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'met10unc' Wed May 02 20:02:42 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'met10xaa' Tue Jun 30 17:35:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Met10Xaa' region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table S2-74 tacr2-tac1-1 1 26 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:11:53 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'val7nme1phe' 97 unspecified role unspecified role bait bait physical association physical association Table S2-75 there is a modification to Val7 to n-methyl Phenylalanine. I have entered as a 'mutation' with the modification in the short label (otherwise the mod ONLY could be entered - and the "mutation" would not be annotated. tacr3-tac3 1 108 unspecified role unspecified role bait bait 126 competitor competitor competitor prey prey 43 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-77 tacr3-tac3-1 1 97 unspecified role unspecified role bait bait 26 competitor competitor competitor prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:12:07 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'val7nme1phe' 26 unspecified role unspecified role prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 17:12:09 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'val7nme1phe' region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-76 there is a modification to Val7 to n-methyl Phenylalanine. I have entered as a 'mutation' with the modification in the short label (otherwise the mod ONLY could be entered - and the "mutation" would not be annotated. npy1r-npy 1 108 unspecified role unspecified role bait bait 43 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-78 npy1r-npy-2 1 51 unspecified role unspecified role bait bait 126 competitor competitor competitor prey prey 43 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-79b npy2r-npy 1 43 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 51 unspecified role unspecified role bait bait physical association physical association Table S2-80 ntsr1-npy 1 130 unspecified role unspecified role bait bait 14 competitor competitor competitor prey prey 14 unspecified role unspecified role prey prey tyr3 125i radiolabel 125i radiolabel I125 125I 125I I125 certain certain sequence position certain certain certain sequence position certain physical association physical association Table S2-81b ntsr1-nts 1 130 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey tyr3 125i radiolabel 125i radiolabel I125 125I 125I I125 certain certain sequence position certain certain certain sequence position certain physical association physical association Table S2-82 ntsr1-nts-1 1 142 unspecified role unspecified role bait bait 96 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 96 competitor competitor competitor prey prey physical association physical association Table S2-83 oprd1-dpdpe-1 1 81 unspecified role unspecified role bait bait 127 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 19 competitor competitor competitor prey prey physical association physical association Table S2-85 oprd1-dpdpe-2 1 96 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 142 unspecified role unspecified role bait bait physical association physical association Table S2-84 oprk1-u50488 1 127 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 81 unspecified role unspecified role bait bait physical association physical association Table S2-86 oprk1-u50488-1 1 94 unspecified role unspecified role bait bait 91 competitor competitor competitor prey prey phe4 mephe methylated phenylalanine MePhe certain certain sequence position certain certain certain sequence position certain undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:22:08 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'met5gly-ol' undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:22:36 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'gly2d-ala' 91 unspecified role unspecified role prey prey phe4 nme1phe N-methyl-L-phenylalanine (2S)-2-methylamino-3-phenylpropanoic acid MOD_RES N-methylphenylalanine N-methyl-L-phenylalanine N-methylated L-phenylalanine N-methylphenylalanine Methyl Methylation NMe1Phe certain certain sequence position certain certain certain sequence position certain undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:22:13 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'gly2d-ala' undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:22:15 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'met5gly-ol' region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-87 oprm1-penk 1 91 competitor competitor competitor prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:21:31 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'gly2d-ala' phe4 mephe methylated phenylalanine MePhe certain certain sequence position certain certain certain sequence position certain 94 unspecified role unspecified role bait bait 91 unspecified role unspecified role prey prey phe4 nme1phe N-methyl-L-phenylalanine (2S)-2-methylamino-3-phenylpropanoic acid MOD_RES N-methylphenylalanine N-methyl-L-phenylalanine N-methylated L-phenylalanine N-methylphenylalanine Methyl Methylation NMe1Phe certain certain sequence position certain certain certain sequence position certain region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:21:33 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'met5gly-ol' undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:22:05 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'gly2d-ala' physical association physical association Table S2-88 oprm1-penk-1 1 91 unspecified role unspecified role prey prey undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:21:59 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'met5gly-ol' phe4 nme1phe N-methyl-L-phenylalanine (2S)-2-methylamino-3-phenylpropanoic acid MOD_RES N-methylphenylalanine N-methyl-L-phenylalanine N-methylated L-phenylalanine N-methylphenylalanine Methyl Methylation NMe1Phe certain certain sequence position certain certain certain sequence position certain region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined undefined mutation mutation mutation certain certain sequence position certain certain certain sequence position certain Wed Jul 06 16:21:55 BST 2016 Sequence change details about this feature cannot be ascertained or do not fit with the current version of the referenced protein, so they have been deleted as a result of our quality control procedures. The original label was 'gly2d-ala' 94 unspecified role unspecified role bait bait physical association physical association Table S2-88 oprl1-penk-1 1 56 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 92 unspecified role unspecified role bait bait 56 competitor competitor competitor prey prey physical association physical association Table S2-89 oprl1-pnoc 1 56 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 92 unspecified role unspecified role bait bait physical association physical association Table S2-90 oprl1-pnoc-1 1 10 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 competitor competitor competitor prey prey 101 unspecified role unspecified role bait bait physical association physical association Table S2-91 htr1a-8_oh_dpat 1 101 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-92 htr1a-8_oh_dpat-1 1 25 competitor competitor competitor prey prey 66 unspecified role unspecified role bait bait 144 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-93 I cannot see a MOD term for iodination at position 3 of an indole ring - so have left as is.... htr1b-iodocyanopindo 1 66 unspecified role unspecified role bait bait 144 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-94 I cannot see a MOD term for iodination at position 3 of an indole ring - so have left as is.... htr1b-iodocyanopin-1 1 59 unspecified role unspecified role bait bait 148 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 148 competitor competitor competitor prey prey physical association physical association Table S2-95 htr2a-ketanserin 1 59 unspecified role unspecified role bait bait 148 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-96 htr2a-ketanserin-1 1 151 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 151 competitor competitor competitor prey prey 149 unspecified role unspecified role bait bait physical association physical association Table S2-97 htr2c-mesulergine 1 151 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 149 unspecified role unspecified role bait bait physical association physical association Table S2-98 htr2c-mesulergine-1 1 41 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 25 competitor competitor competitor prey prey 113 unspecified role unspecified role bait bait physical association physical association Table S2-99 htr4-gr_113808 1 113 unspecified role unspecified role bait bait 41 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-100 htr4-gr_113808-1 1 25 competitor competitor competitor prey prey 129 unspecified role unspecified role bait bait 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-101 htr5a-lsd_lysergic_a 1 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 129 unspecified role unspecified role bait bait physical association physical association Table S2-102 htr5a-lsd_lysergic-1 1 25 competitor competitor competitor prey prey 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 112 unspecified role unspecified role bait bait physical association physical association Table S2-103 htr6-lsd_lysergic_ac 1 112 unspecified role unspecified role bait bait 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-104 htr6-lsd_lysergic_-1 1 44 unspecified role unspecified role bait bait 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 25 competitor competitor competitor prey prey physical association physical association Table S2-104 htr7-lsd_lysergic_ac 1 35 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 44 unspecified role unspecified role bait bait physical association physical association Table S2-105 htr7-lsd_lysergic_-1 1 150 unspecified role unspecified role bait bait 131 competitor competitor competitor prey prey 61 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-106 nr3c1-dexamethasone 1 150 unspecified role unspecified role bait bait 61 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-107 nr3c1-dexamethason-1 1 128 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 128 competitor competitor competitor prey prey 24 unspecified role unspecified role bait bait physical association physical association Table S2-110 esr1-17beta_estradio 1 152 unspecified role unspecified role bait bait 78 unspecified role unspecified role prey prey physical association physical association Table S2-109 pgr-r 1 128 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 24 unspecified role unspecified role bait bait physical association physical association Table S2-111 pgr-r-1 1 65 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 competitor competitor competitor prey prey physical association physical association Table S2-112 ar-mibolerone 1 65 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-113 ar-mibolerone-1 1 121 competitor competitor competitor prey prey 121 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 85 unspecified role unspecified role bait bait physical association physical association Table S2-114 vipr1-vip 1 85 unspecified role unspecified role bait bait 121 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-115 vipr1-vip-1 1 155 competitor competitor competitor prey prey avp sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain methyl_tyr metyr methylated tyrosine MeTyr certain certain sequence position certain certain certain sequence position certain β-mercapto-β,β-cyclopentamethylene-propionyl- uncategorized protein modification uncategorized protein modification certain certain sequence position certain certain certain sequence position certain This molecule is probably H-5350 from Bachem:- β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (d(CH2)5 1,Tyr(Me)2,Arg8)-Vasopressin This molecule is probably H-5350 from Bachem:- β-Mercapto-β,β-cyclopentamethylene-propionyl-Tyr(Me)-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (d(CH2)5 1,Tyr(Me)2,Arg8)-Vasopressin 155 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 158 unspecified role unspecified role bait bait physical association physical association Table S2-116 avpr1a-vip 1 158 unspecified role unspecified role bait bait 121 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-117 cacna1b-co16a-1 1 154 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 70 unspecified role unspecified role bait bait 28 competitor competitor competitor prey prey physical association physical association Table S2-120 cacna1b-co16a-2 1 4 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-119 slc6a2-nisoxetine 1 70 unspecified role unspecified role bait bait 154 unspecified role unspecified role prey prey region 125i radiolabel 125i radiolabel I125 125I 125I I125 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table S2-121 slc6a2-nisoxetine-1 1 5 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role bait bait 125 competitor competitor competitor prey prey physical association physical association Table S2-122 slc6a3-gbr12909_vano 1 5 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 98 unspecified role unspecified role bait bait physical association physical association Table S2-123 slc6a3-gbr12909_va-1 1 135 unspecified role unspecified role bait bait 82 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 110 competitor competitor competitor prey prey physical association physical association Table S2-124 slc6a4-imipramine 1 82 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 135 unspecified role unspecified role bait bait physical association physical association Table S2-125 cnr1-win_55212_2-2 1 39 unspecified role unspecified role prey prey 140 unspecified role unspecified role bait bait 16 competitor competitor competitor prey prey physical association physical association Table S2-126 ptgs1-arachidonic_ac 1 39 unspecified role unspecified role prey prey 140 unspecified role unspecified role bait bait physical association physical association Table S2-127 ptgs1-arachidonic_-1 1 39 unspecified role unspecified role prey prey 75 competitor competitor competitor prey prey 115 unspecified role unspecified role bait bait direct interaction direct interaction Table S2-128 ptgs2-arachidonic_ac 1 115 unspecified role unspecified role bait bait 39 unspecified role unspecified role prey prey direct interaction direct interaction Table S2-129 ptgs2-arachidonic_-1 1 39 unspecified role unspecified role prey prey 79 competitor competitor competitor prey prey 6 unspecified role unspecified role bait bait physical association physical association Table S2-130 alox5-arachidonic_ac 1 39 unspecified role unspecified role prey prey 6 unspecified role unspecified role bait bait physical association physical association Table S2-131 alox5-arachidonic_-1 1 109 competitor competitor competitor prey prey 106 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 104 unspecified role unspecified role bait bait direct interaction direct interaction Table S2-132 nos2-arginine 1 104 unspecified role unspecified role bait bait 106 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined direct interaction direct interaction Table S2-133 nos2-arginine-1 1 104 unspecified role unspecified role bait bait 109 competitor competitor competitor prey prey 106 unspecified role unspecified role prey prey region 3h radiolabel 3h radiolabel 3H tritium H3 undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined direct interaction direct interaction Table S2-134 htr1a-8_oh_dpat-2 1 95 unspecified role unspecified role prey prey 37 unspecified role unspecified role bait bait 49 competitor competitor competitor prey prey physical association physical association Table S2-134 maoa-clorgyline 1 37 unspecified role unspecified role bait bait 95 unspecified role unspecified role prey prey physical association physical association Table S2-135 maoa-clorgyline-1 1 34 unspecified role unspecified role bait bait 156 competitor competitor competitor prey prey 95 unspecified role unspecified role prey prey physical association physical association Table S2-136 maob-deprenyl_selegi 1 95 unspecified role unspecified role prey prey 34 unspecified role unspecified role bait bait physical association physical association Table S2-137 cxcr2-il8-2 1 105 competitor competitor competitor prey prey 18 unspecified role unspecified role bait bait 107 unspecified role unspecified role prey prey physical association physical association Table S2-138 The authors have confirmed that the substrate described as "acetyl-6-methylthiocholine", is really acetyl-(beta-methyl)thiocholine, and that the iodide salt was used (CHEBI:73545). ache-acetyl_beta_met 1 18 unspecified role unspecified role bait bait 107 unspecified role unspecified role prey prey physical association physical association Table S2-139 The authors have confirmed that the substrate described as "acetyl-6-methylthiocholine", is really acetyl-(beta-methyl)thiocholine, and that the iodide salt was used (CHEBI:73545).