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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>UniProt</shortLabel>
        <fullName>UniProt</fullName>
      </names>
      <xref>
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    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5'-monophosphate at 1.38 A resolution.</fullName>
        </names>
        <bibref>
          <xref>
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          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">A new crystal form of human histidine triad nucleotide-binding protein 1 (hHINT1) in complex with adenosine 5'-monophosphate at 1.38 A resolution.</attribute>
            <attribute name="journal" nameAc="MI:0885">Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.</attribute>
            <attribute name="publication year" nameAc="MI:0886">2012</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Dolot R., Ozga M., Włodarczyk A., Krakowiak A., Nawrot B.</attribute>
            <attribute name="contact-email" nameAc="MI:0634">rdolot@cbmm.lodz.pl</attribute>
            <attribute name="author-announcement">01-March-2013: Contacted by IntAct-Help.</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
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        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Dolot R., Ozga M., Włodarczyk A., Krakowiak A., Nawrot B.</attribute>
          <attribute name="contact-email" nameAc="MI:0634">rdolot@cbmm.lodz.pl</attribute>
          <attribute name="accepted">Accepted 2013-FEB-25 by ORCHARD</attribute>
          <attribute name="author-announcement">01-March-2013: Contacted by IntAct-Help.</attribute>
          <attribute name="journal" nameAc="MI:0885">Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun.</attribute>
          <attribute name="publication year" nameAc="MI:0886">2012</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
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      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>hint1_human</shortLabel>
          <fullName>Adenosine 5'-monophosphoramidase HINT1</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">Protein kinase C inhibitor 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Protein kinase C-interacting protein 1</alias>
          <alias type="gene name" typeAc="MI:0301">HINT1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">HINT</alias>
          <alias type="gene name synonym" typeAc="MI:0302">PKCI1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">PRKCNH1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Desumoylating isopeptidase HINT1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Histidine triad nucleotide-binding protein 1</alias>
        </names>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6YQM" version="SP_206"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
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        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MADEIAKAQVARPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHLMIVGKKCAADLGLNKGYRMVVNEGSDGGQSVYHVHLHVLGGRQMHWPPG</sequence>
        <attributeList>
          <attribute name="crc64">6C2B0119370384AA</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="3" imexId="IM-18687-1">
        <names>
          <shortLabel>hint1</shortLabel>
        </names>
        <xref>
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        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="4">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-55" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <hostOrganismList>
              <hostOrganism ncbiTaxId="83333">
                <names>
                  <shortLabel>ecoli</shortLabel>
                  <fullName>Escherichia coli (strain K12)</fullName>
                </names>
              </hostOrganism>
            </hostOrganismList>
            <stoichiometry value="2"/>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="3d-resolution" nameAc="MI:0632">1.38 A</attribute>
          <attribute name="3d-r-factors" nameAc="MI:0631">R-factor: 0.123 R-free: 0.161</attribute>
          <attribute name="figure legend" nameAc="MI:0599">Table 1</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
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