UniProt UniProt http://www.uniprot.org Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Hum. Mol. Genet. (0964-6906) 2006 imex curation Yatsenko A.N., Roy A., Chen R., Ma L., Murthy L.J., Yan W., Lamb D.J., Matzuk M.M. mmatzuk@bcm.tmc.edu 17-Jun-2013: Contacted by IntAct-Help. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Yatsenko A.N., Roy A., Chen R., Ma L., Murthy L.J., Yan W., Lamb D.J., Matzuk M.M. mmatzuk@bcm.tmc.edu Accepted 2013-JUN-05 by MGT 17-Jun-2013: Contacted by IntAct-Help. Hum. Mol. Genet. (0964-6906) 2006 Only protein-protein interactions imex curation klh10_human Kelch-like protein 10 KLHL10 protein protein human Homo sapiens Human MEMESAAASTRFHQPHMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVEEYAARRDNFPGLALRDEVKYSASTSTLPV 669A5C3D46472915 cul3_mouse Cullin-3 Cul3 protein protein mouse Mus musculus Mouse MSNLSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNNNFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNNVENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLAENSASVYIKKVEARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPNGLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKHILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKEIESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 841E20407BD076A3 klhl10-klhl10 1 2 unspecified role unspecified role prey prey 2 unspecified role unspecified role bait bait Q6JEL2:p.Ala313Thr mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain A T Wed May 02 20:13:46 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ala313thr' Tue Jun 30 15:42:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ala313Thr' UnuiProt FTId: VAR_069358 Q6JEL2:p.Gln216Pro mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Q P Wed May 02 16:48:26 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln216pro' Tue Jun 30 18:15:03 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln216Pro' UniProt FTId: VAR_069357 physical association physical association 4A klhl10-klhl10-1 1 2 unspecified role unspecified role bait bait 2 unspecified role unspecified role prey prey Q6JEL2:p.Ala313Thr mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain A T Wed May 02 17:57:03 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ala313thr' Tue Jun 30 16:10:20 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Ala313Thr' UnuiProt FTId: VAR_069358 Q6JEL2:p.Gln216Pro mutation disrupting mutation disrupting interaction mutation disrupting certain certain sequence position certain certain certain sequence position certain Q P Wed May 02 15:47:32 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln216pro' Tue Jun 30 17:31:17 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln216Pro' UniProt FTId: VAR_069357 physical association physical association 4A klhl10-cul3 1 2 unspecified role unspecified role bait bait 3 unspecified role unspecified role prey prey physical association physical association 4A