IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Crystal structure of activated ModE reveals conformational changes involving both oxyanion and DNA-binding domains. Crystal structure of activated ModE reveals conformational changes involving both oxyanion and DNA-binding domains. J. Mol. Biol. (0022-2836) 2003 imex curation Schüttelkopf A.W., Boxer D.H., Hunter W.N. w.n.hunter@dundee.ac.uk 30-Sept-2013: Contacted by IntAct-Help. Only protein-protein interactions ecoli Escherichia coli (strain K12) x-ray diffraction x-ray crystallography X-ray X-ray x-ray diffraction predetermined predetermined participant predetermined Schüttelkopf A.W., Boxer D.H., Hunter W.N. w.n.hunter@dundee.ac.uk Accepted 2013-SEP-26 by PPORRAS 30-Sept-2013: Contacted by IntAct-Help. J. Mol. Biol. (0022-2836) 2003 Only protein-protein interactions imex curation molybdate molybdate [MoO4](2-) Molybdate molybdate MOLYBDATE ION tetraoxidomolybdate(2-) tetraoxidomolybdate(VI) small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) MEFBJEMVZONFCJ-UHFFFAOYSA-N MEFBJEMVZONFCJ-UHFFFAOYSA-N mode_ecoli DNA-binding transcriptional dual regulator ModE modE modR b0761 JW0744 protein protein ecoli Escherichia coli (strain K12) MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGISYKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDVLSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKVAITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCEVLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC 9A17636162F4233E mode-molybdate-1 1 2 unspecified role unspecified role neutral component neutral component chemical synthesis Chemical synthesis (Chemical synthesis) 3 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction Fig.s 1b, 2, 3b R = 0.21; Rwork = 0.21; Rfree = 0.25 2.75 A In one of the two dimers that were crystallized a third molybdate ion was found in the dimerization interface. It is not clear whether this is an artifact of the methodology. The crystal was originally grown in the presence of a 24mer oligonucleotide representing the signal sequence of the modABCD operon but it did not co-crystallize.