mbinfo MBInfo http://www.mechanobio.info/ Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. Nature (0028-0836) 2002 imex curation Ling K., Doughman R.L., Firestone A.J., Bunce M.W., Anderson R.A. The various immunoprecipitation experiments between PIPKI-gamma661 and talin (Fig 1b, 4a, S1c, S2b) and the colocalization of PIPKI-gamma661 and talin (Fig 2) could not be curated since the specific talin isoform (talin 1 Vs talin 2) involved in these cases could not be identified. raanders@facstaff.wisc.edu 8-May-2012: Contacted by IntAct-Help. Only protein-protein interactions rat-nrk Rattus norvegicus kidney fibroblast cell line NRK nrk Rat kidney fibroblast cell line NRK fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Ling K., Doughman R.L., Firestone A.J., Bunce M.W., Anderson R.A. The various immunoprecipitation experiments between PIPKI-gamma661 and talin (Fig 1b, 4a, S1c, S2b) and the colocalization of PIPKI-gamma661 and talin (Fig 2) could not be curated since the specific talin isoform (talin 1 Vs talin 2) involved in these cases could not be identified. raanders@facstaff.wisc.edu Accepted 2013-APR-24 by ORCHARD 8-May-2012: Contacted by IntAct-Help. Nature (0028-0836) 2002 Only protein-protein interactions imex curation o70161-1 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma PIPKIgamma661 Pip5k1c Kiaa0589 Phosphatidylinositol 4-phosphate 5-kinase type I gamma protein protein mouse Mus musculus Mouse MELEVPDEAESAEAGAVTAEAAWSAESGAAAGMTQKKAGLAEAPLVTGQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAEGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSSSLKSSPSKKGRGALLAVKPLGPTAAFSASQIPSEREDVQYDLRGARSYPTLEDEGRPDLLPCTPPSFEEATTASIATTLSSTSLSIPERSPSDTSEQPRYRRRTQSSGQDGRPQEEPHAEDLQKITVQVEPVCGVGVVPKEEGAGVEVPPCGASAAASVEIDAASQASEPASQASDEEDAPSTDIYFPTDERSWVYSPLHYSARPASDGESDT 4A3B71E4465B83C3 fak1_rat Focal adhesion kinase 1 Ptk2 Fak Fak1 Focal adhesion kinase-related nonkinase Protein-tyrosine kinase 2 p125FAK pp125FAK protein protein rat Rattus norvegicus (Rat) Rat MAAAYLDPNLNHTPSSSTKTHLGTGTERSPGAMERVLKVFHYFESSNEPTTWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKLANNEKQGMRTHAVSVSETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYLSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQISGYPGSHGIPAMAGSIYPGQASLLDQTELWNHRPQEMSMWQPSVEDSAALDLRGMGQVLPPHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSFQGPTGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLSNLSSISSPAESYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPILPASTHREIEMAQKLLNSDLGELISKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKMLGQTRPH DIP protein O35346 original sequence version: 101 DIP protein O35346 original sequence version: 124 3AFB4ED682D14A33 pip5k1c-ptk2-1 1 2 unspecified role unspecified role neutral component neutral component 3 unspecified role unspecified role neutral component neutral component colocalization colocalization Fig 4B.