MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Activation of macrophage-stimulating protein by human airway trypsin-like protease. Activation of macrophage-stimulating protein by human airway trypsin-like protease. FEBS Lett. (0014-5793) 2012 imex curation Orikawa H., Kawaguchi M., Baba T., Yorita K., Sakoda S., Kataoka H. IBD - Inflammatory bowel disease suggested by lperfetto mejina@fc.miyazaki-u.ac.jp Only protein-protein interactions in vitro In vitro protease assay protease assay western blot western blot Immuno blot Immuno blot Orikawa H., Kawaguchi M., Baba T., Yorita K., Sakoda S., Kataoka H. IBD - Inflammatory bowel disease suggested by lperfetto Preparation of recombinant HPGL/MST (P26927) is described in PMID:19456860. mejina@fc.miyazaki-u.ac.jp FEBS Lett. (0014-5793) 2012 Only protein-protein interactions imex curation hgfl_human Hepatocyte growth factor-like protein D3F15S2 DNF15S2 HGFL Macrophage stimulatory protein Macrophage-stimulating protein MST1 protein protein human Homo sapiens Human MGWLPLLLLLTQCLGVPGQRSPLNDFQVLRGTELQHLLHAVVPGPWQEDVADAEECAGRCGPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLFQKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSHGPWCYTMDPRTPFDYCALRRCADDQPPSILDPPDQVQFEKCGKRVDRLDQRRSKLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKMVCGPSGSQLVLLKLERSVTLNQRVALICLPPEWYVVPPGTKCEIAGWGETKGTGNDTVLNVALLNVISNQECNIKHRGRVRESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEGIIIPNRVCARSRWPAVFTRVSVFVDWIHKVMRLG DIP protein P26927 original sequence version: 144 2E4B3C7D4AA9B566 tm11d_human Transmembrane protease serine 11D TMPRSS11D Airway trypsin-like protease HAT protein protein human Homo sapiens Human MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVEYNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKFQFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLITLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI mint homomint F4BC1DB020CFBBD0 mst1-tmprss11d 1 HAT 3 predetermined predetermined participant predetermined western blot western blot Immuno blot Immuno blot enzyme enzyme neutral component neutral component purified purified proMSP 2 edman degradation edman degradation western blot western blot Immuno blot Immuno blot enzyme target enzyme target substrate substrate neutral component neutral component purified purified other modification other modification uncategorized protein modification uncategorized protein modification modified residue ms mass detection of residue modification modified residue ms certain certain sequence position certain certain certain sequence position certain c-terminus his tag his tag Hexa-His-tag 6-His-tag Histidine-tag Hexa-His-tag Histidine-tag 6-His-tag c-term range C-terminal range c-term range c-term range C-terminal range c-term range crigr-cho chinese hamster ovary cell line cho chinese hamster ovary cell line Also called LR73 cells. cleavage cleavage reaction cleavage F1 homomint mint cleavage of P26927 at the arg483-val484 peptide bond O60235 is required for cleavage of P26927 O60235 increases activity of P26927 O60235 increases quantity of PRO_0000028086 O60235 increases quantity of PRO_0000028087 Processing of HGFL/MST (P26927) by TM11D/HAT (O60235) was suppressed at higher sodium chloride (NaCl) concentrations (tested at 50, 150 and 200 millimolar NaCl).