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        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
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        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
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        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
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        <names>
          <fullName>Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells.</fullName>
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            <attribute name="publication title" nameAc="MI:1091">Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells.</attribute>
            <attribute name="journal" nameAc="MI:0885">Cell (0092-8674)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2011</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
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            <attribute name="author-list" nameAc="MI:0636">Cebrian I., Visentin G., Blanchard N., Jouve M., Bobard A., Moita C., Enninga J., Moita L.F., Amigorena S., Savina A.</attribute>
            <attribute name="remark-internal">Colocalizations not captured as appear to be indicative of subcellular location not interactions.</attribute>
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            <attribute name="author-announcement">14-Mar-2012: Contacted by JYOTI.</attribute>
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            <names>
              <shortLabel>human-bmdc</shortLabel>
              <fullName>Homo sapiens Bone Marrow derived dendritic cells</fullName>
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              <names>
                <shortLabel>bmdm-1</shortLabel>
                <fullName>bone marrow-derived macrophage</fullName>
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          </names>
        </organism>
        <sequence>MIPRKRYGSKNTDQGVYLGLSKTQVLSPATAGSSSSDIAPLPPPVTLVPPPPDTMSCRDRTQEFLSACKSLQTRQNGIQTNKPALRAVRQRSEFTLMAKRIGKDLSNTFAKLEKLTILAKRKSLFDDKAVEIEELTYIIKQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMVKIFLILIVFFIIFVVFLA</sequence>
        <attributeList>
          <attribute name="crc64">EE8616A226888501</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>sc22b_human</shortLabel>
          <fullName>Vesicle-trafficking protein SEC22b</fullName>
          <alias type="gene name" typeAc="MI:0301">SEC22B</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SEC22L1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SEC22 vesicle-trafficking protein homolog B</alias>
          <alias type="gene name synonym" typeAc="MI:0302">SEC22 vesicle-trafficking protein-like 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">ER-Golgi SNARE of 24 kDa</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="O75396" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000463393" version="SP_192" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A8K1G0" version="SP_88" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1058865" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000265808" version="SP_192" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000578049" version="SP_192" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000139" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005484" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005789" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005793" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006888" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006890" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008021" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0012507" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0015031" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016021" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019905" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030133" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030137" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030670" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0031201" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0033116" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042470" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045732" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0048280" version="SP_192"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902902" version="SP_192"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001388" version="SP_192"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR010908" version="SP_192"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011012" version="SP_192"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR042855" version="SP_192"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR044565" version="SP_192"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="O75396" version="SP_192"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NUP" version="SP_192"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2NUT" version="SP_192"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EGD" version="SP_192"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3EGX" version="SP_192"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004883.3"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-204005" version="SP_192"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5694530" version="SP_192"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811434" version="SP_192"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-1236974" version="SP_192"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-50458N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMTFHYIIEQGVCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHGKKVPTVSRPYSFIEFDTFIQKTKKLYIDSRARRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLSSLSKKYRQDAKYLNMRSTYAKLAAVAVFFIMLIVYVRFWWL</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein O75396 original sequence version: 126</attribute>
          <attribute name="crc64">29B4C55961C5A044</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-16636-1">
        <names>
          <shortLabel>sec22b-stx5</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-5376508" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16636-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="7">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Supp. Fig. 1C</attribute>
        </attributeList>
      </interaction>
      <interaction id="8" imexId="IM-16636-2">
        <names>
          <shortLabel>sec22b-stx4</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-5376558" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="imex source"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-16636-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="9">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="10">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">Supp. Fig. 1D</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>