IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ PPTX, a pentraxin domain-containing protein, interacts with the T1 domain of K v 4. PPTX, a pentraxin domain-containing protein, interacts with the T1 domain of K v 4. J. Neurosci. Res. (0360-4012) 2009 imex curation Harvey M., Karolat J., Sakai Y., Sokolowski B. bsokolow@health.usf.edu 19-Jun-2012: Contacted by JYOTI. Only protein-protein interactions chick-cochlea Chick cochlea cochlea fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Harvey M., Karolat J., Sakai Y., Sokolowski B. bsokolow@health.usf.edu Accepted 2012-FEB-09 by PPORRAS J. Neurosci. Res. (0360-4012) 2009 Only protein-protein interactions imex curation PPTX, a pentraxin domain-containing protein, interacts with the T1 domain of K v 4. PPTX, a pentraxin domain-containing protein, interacts with the T1 domain of K v 4. J. Neurosci. Res. (0360-4012) 2009 imex curation Harvey M., Karolat J., Sakai Y., Sokolowski B. bsokolow@health.usf.edu 19-Jun-2012: Contacted by JYOTI. Only protein-protein interactions chick-cochlea Chick cochlea cochlea 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Harvey M., Karolat J., Sakai Y., Sokolowski B. bsokolow@health.usf.edu Accepted 2012-FEB-09 by PPORRAS 19-Jun-2012: Contacted by JYOTI. J. Neurosci. Res. (0360-4012) 2009 Only protein-protein interactions imex curation q5umh8_chick protein protein chick Gallus gallus (Chicken) Chicken MLPGGVLSLLMLFCVFRASASVLDEGDDYDLMYVNLDNEIEGPVLGTEESASCDCQREHTEWDKLFIMLENSQMKENMMLQALEDGLKADVQAIRAELNQLTAGLAGTFSSTVQQLTSHALAQLEQALQRNGDQPEDAERLCESQQGKVLEQVLQLSHNVSARLGQLESSWLRWAEREAQETAFQLQQDKLGHSREDNLLLNTLWKELQQTRSELKASQKWASQHLLPAGYETAILFPMRSRKIFGSIHPTAAMTLSSFTVCVWVKATEALDKTIIFSYGTKLNPYEIQLYLSRQSAVLAVGSAQHKLAARDVVVPGKWIHLCGTWSSDNGTASLWVDGELTATAVGIADTHIVPDGGILQVGQEKNGCCVGGGFDEALAFSGKLTGLNLWDRVLSTEEIAAQGGEDACSSRGNIVGWGVTEVLLYGGAQYVS 516FC6C8D54958D8 q8uw33_chick Potassium voltage-gated channel subfamily D member 2 kv4.2 Voltage-gated potassium channel subunit Kv4.2 protein protein chick Gallus gallus (Chicken) Chicken MAAGVPAWLPFARAAAIGWMPVATGPMPAAPRQERKRSQDSLIVLNVSGIQFQTWLDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRQECISAYDEELAFFGIIPEIIGDCCYEEYKDRRRENAERLQDDADQDHTAESSLPSMTARQRMWRAFENPHTSTLALVFYYVTGFFIAVSVIANVVETVPCGVSPGRIKELPCGERYAVAFFCLDTACVMIFTVEYLLRLLAAPSRYKFVRSVMSIIDVVAIMPYYIGLVMTDNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMYYAEKGSSASKFTSIPAAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQKKARLARIRAAKSGSANAYMQSKRNGLLSNQLQQSSSEEEQAFVSKSGSSFETQHHHLLHCLEKTTNHEFVDEQLYEESCMEVSTVNRPPSHSPSLSSQQGVTGTCCSRRHKKTYRIPNTALTGSRHGSVQELSTIQIRCVERTPLSNSRSSLNAKVEECVKLNCEQPYVTTAIISIPTPPVTTPEGDDRPESPEYSGGNIVRVSAL q5umh8-q8uw33-4 1 3 unspecified role unspecified role neutral component neutral component 4 unspecified role unspecified role neutral component neutral component colocalization colocalization Fig. 1 q5umh8-q8uw33-6 2 3 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain region required to bind necessary binding region required to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain Q8UW33:p.Glu118Ile mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain E I Wed May 02 19:33:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'glu118ile' Tue Jun 30 18:59:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Glu118Ile' Q8UW33:p.[Asp86Ala;Glu118Ile] mutation disrupting mutation disrupting interaction mutation disrupting mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain D A certain certain sequence position certain certain certain sequence position certain E I Wed May 02 17:09:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'asp86ala,glu118ile' Tue Jun 30 19:46:22 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Asp86Ala;Glu118Ile]' physical association physical association Fig. 3