IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Proteins interacting with Caenorhabditis elegans Galpha subunits. Proteins interacting with Caenorhabditis elegans Galpha subunits. Comp. Funct. Genomics (1531-6912) 2003 imex curation Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. For the "mutants" I have added separately only as Baits - and added a comment for prey positive reactions.(there are NO instances of reaction with mutant-only preys). p53 not included (positive control) as no species info given. plasterk@niob.knaw.nl 20-Jun-2012: Contacted by JYOTI. C. elegans prey cDNA library, gift of R. Barstead. Only protein-protein interactions caeel-mixed_stage Caenorhabditis elegans mixed stage organisms mixed_stage C. elagans mixed stage organisms 2h fragment pooling two hybrid fragment pooling approach 2h fragment pooling nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. For the "mutants" I have added separately only as Baits - and added a comment for prey positive reactions.(there are NO instances of reaction with mutant-only preys). p53 not included (positive control) as no species info given. For interactions involving GOA-1/C05D2.6 and also T22A3.3/GPA-6: the amino acid numbers given for the "fragment" exceed the length of any of the molecules involved in the interaction. plasterk@niob.knaw.nl Accepted 2012-APR-20 by ORCHARD C. elegans prey cDNA library, gift of R. Barstead. Comp. Funct. Genomics (1531-6912) 2003 Only protein-protein interactions imex curation Proteins interacting with Caenorhabditis elegans Galpha subunits. Proteins interacting with Caenorhabditis elegans Galpha subunits. Comp. Funct. Genomics (1531-6912) 2003 imex curation Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. For the "mutants" I have added separately only as Baits - and added a comment for prey positive reactions.(there are NO instances of reaction with mutant-only preys). p53 not included (positive control) as no species info given. plasterk@niob.knaw.nl 20-Jun-2012: Contacted by JYOTI. C. elegans prey cDNA library, gift of R. Barstead. Only protein-protein interactions caeel-mixed_stage Caenorhabditis elegans mixed stage organisms mixed_stage C. elagans mixed stage organisms 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Cuppen E., van der Linden A.M., Jansen G., Plasterk R.H. For the "mutants" I have added separately only as Baits - and added a comment for prey positive reactions.(there are NO instances of reaction with mutant-only preys). p53 not included (positive control) as no species info given. plasterk@niob.knaw.nl Accepted 2012-APR-20 by ORCHARD 20-Jun-2012: Contacted by JYOTI. C. elegans prey cDNA library, gift of R. Barstead. Comp. Funct. Genomics (1531-6912) 2003 Only protein-protein interactions imex curation dmd_caeel Dystrophin-1 F15D3.1 dys-1 protein protein caeel Caenorhabditis elegans MLFSGASTAKPKKDEKKDKKSDRDPKNELQEWVFVRWANHLLGTERLTDYKSLQDGSNAIFVYQAIIGQTMAVLGNPSDDWPNVLQNIGDSKTNPQEVMEGQQKAVLSAWWQLVQFFWKNNAPVQLREEKLSEAIKQWCIEVMKSYEEIDVYDFTSSFRDGHAFNYLIHSYDRKLINLTKTAEMSAIDRIENAFAVAEKTWNVPRLLNPKDLHSDQLDSHSVLCYLMSLYLAMISTSKIETELEAQQIQQQKVAALLASHKMLSSQPSTSSSSALQIPPQTPPTAHHQAMLDRGKSFEQSAEGEVRSRKSSSSSQKSGKSKKARREEQLAEFKSCIEQVLTWLLEAEDELTTLTQMPRVELASVRSQFSDFESFMSSLTDSQDTVGRVLLRGQMLSNKSESEEEKESIGANLHLVNTRWEALREQAMQEQAVLQQQIHLLQQSELDTISQWLDAAELEIESFGPLAADSSQALRQIELHTKFQQKLNDFQETIDKLESFVAVVDEENDASVATLEDALSAVSVRWGHVCEWAEKRATKLDGLADLLDKTNEVFENLSGWLAERENELMTGLKSAHHLENEEQVAQQVRRLQKTEEQLEQEHASFVRLSQLSCELVGRLDDSNGAAANAVRLSLDSITQRWDNLVARIEEHGKTLVKSGKADVKQVQESQNEQKEQPASSEGLSTDTEGEEQKNQLVDKFLLHISKLSHELEPLQDWSEKFEVSRKKDDIRKMMNTCQEKLIQIKEQEARVNRLQLELEHLHVAKLNARQLKRANDAFEQFAKGWARIVTKISEAMNVLTGQEAGGNGNGSEEAAVAAKIEQWIEAVDKVINELSQLPVNERRSRIDKLEQQLQVQDKNVGFIEKDLLKKAILKKGLEIAGKRLAALKVEEKPVEKEEQLVLSNSEEPEAEKHVTFVQETTEKPAPLQEPTSEAQLLEELDGPWSRVGDVVAIEHDLLRAKRAVDTARNSQMSNETVEKAETRKAEMEEKRRVTMSARSKFRMAEETLEEIERNLDRLQVSDLEIADLVRGLEQEAAKLGERVSQRKEAERTAEKILSMDDDEISQEIVIKTKDSTEKLIKRWNQLELDLEENLRKAKRDQDVFIQKRLREGEEALNEIKTAIEGKRESLDAETAAENLDHLESSLDNISSLFGEIGSLPMDDNSREKLSKLAKAKDQITARANEALAALTRTVSECEDFEKQIMLFQNWSARIGFLLQARKSADISAFDIPHEYHEDLGNEAELIPKLSREFEEWTVKLNEMNSTATEKDDSARMREQLNHANETMAELKRKFNEFKRPKGFEEKLEKVITTLSNVEMGLDDTTGIDGSECGGALMEVRALVRMLDGAQEKWKDLAENREQLVKDRVLDEETSKETLQKLQYAKTKSKELYERSSTCIERLEDCVEMYQRLKMESDEIERFLEEMEGKLDQYAASDRPEEAEIVNELISEWNRNEAAMKNAEHLQRQLNERAIKIPDDVLSLKRLRADALKNRLNSWCRTIQEMSEDDESALLEIDELHQNLEKELKLVSDKEPSKIAEKLRFLRADRDRLSSRTRKLAAKNPRLAATSSDVLAGLNQKWKELEVKASAEKAPAPELRDARLSSPSEQPFDKRVQELCDLFENLEAQLDFNGSPVSMVTEYQKRVENLDEYLDEYRPALDDTIEEGRKIAETGRLELQTHSAIEKLDELTNRIEQVEVELDKHRDKVPSLVEQHEQLKKDIDSFLLVLDVFTDRNLDDVDIAKSTRKELAERDSHIVSLTSRATAIHCALPGKGPQLHDVTLDKLRDRIEKLEARLSATEKKPVETVKSTIPDRPEVPEEPEKSSPDRTSRSSLQLAMEAYGTATEDDSVISEAVTVGQKSVDQVDPVEQLEPVEPVEPKLEVKQLKDEATEEEEKRTIILPDETEKVIETIPAARPSAGPSEGTVAEVSTSEILKARPAQESIERTVREVPVDEYEETANISSGDELQDHKISSAVPDSESEIASMFEVLDSIEDSHTNFEEFPFDYLDSADDDLKKTLLKLESCEKTLAKNEMTINIAQAENARERITMLRQMALQRKDKLPKFNEEWNAMQELIQLADALVDEAERYESDQIPQMDRKSAPNVLGELRKRVANAEGPVIDLVKKLSQLVPRMQEDSPKSQDIRQKVYGIEDRFRRVGQAEGAAISKALSSALTEPELKLELDEVVRWCEMAEKEAAQNVNSLDGDGLEKLDGRLAQFTKELQERKDDMVQLEMAKNMIIPSLKGDAHHDLRRNFSDTAKRVAMVRDELSDAHKWVATSRDTCDTFWADIDSLEQLARDVVRRANGIRMAVIYTPSRENVEGVLRDVQRLKMSIGDVKKRVQTANLPPAIKLAGKNAKRVVQVLTETATTIADCHDIPTYLIDEMNDSGGDTTESRSTVVEMTSVHTKQSSSSSSNKTPSAGGESDDAHTLNGDDEQSEEDQKIYSRESSSTLPRGVSSLGSTGSSGVLDPVAVQLTHTRHWLHDVERDASITVDLAQWQPARELWQSIQGIIDEIRLRSVHVTGAHDASPNRQVRQQAAQLLTEMRRTIENCEKRCLILNQISDIARQNEASRNEMELWLKSASDVIGERRVEELSEEVVRQELQVLERVVEQLTERKDKMAEINSQANKIVDTYTKDEAHNLSHLLSRLNMSWTKFNDNIRIRRAVLEASLRSRRDFHSALSEFEKWLSRQEDNCSKLSADTSNHQAIKDTSKRKNWTQSFKTLNAELNAHEDVMKSVEKMGKMLAESLESGNEKVELLKRVGETTRRWTALRKTTNEIGERLEKAEQEWEKLSDGLADLLSWVEAKKQAIMDEQPTGGSLSAVMQQASFVKGLQREIESKTANYKSTVEEAHSFLMQHDLRPKLHSPHVLDDDYEKEELANLEQRRRGLEINANCERLKKNWAELGIEVESWDKLVQHAMQRLQELERNLAECQLHLTSSENEIETMKAVEKIHLEDLKIAREETDQISKRIDEVRLFVDDVNDAAARLLAEDLKLDEHAKGQIEHVNKRYSTLKRAIRIRQAAVRNAASDFGPTSEHFLNQSVTLPWQRAISKSNLLPYYIEQTSEKTQWEHPVWVEIVKELSQFNRVKFLAYRTAMKLRALQKRLCLDLVDLTLLEKAFVRLKGLSAEECPGLEGMVCALLPMYEALHAKYPNQVQSVSLAVDICINFLLNLFDQSRDGIMRVLSFKIAMIVFSNIPLEEKYRYLFKLVSQDGHATQKQIALLLYDLIHIPRLVGESAAFGGTNVEPSVRSCFETVRLAPTISEGAFIDWVKKEPQSIVWLAVMHRLVISESTKHASKCNVCKMFPIIGIRYRCLTCFNCDLCQNCFFSQRTAKSHRTNHPMQEYCEKTTSSDDARDFAKMIRNKFRASKRQKGYLPIDVAEEGIPLTCPPAKVTNQATEQMNADTSQMTAHLAKLSAEHGGGAEHMEPVQSPLQIINQVEQLQRDEMDQMLHRLQFENKQLRKELEWKRGAASTMEIDRSSKRHQERHQSESRGGTLPLRNGRSVVSLKSTQSQNDVMDEAKALRLHKQRLEHRSRILEQQNEQLEMQLQRLKKVIDAQKQQAPLSTNSLLRGSHHQPWSPERARSGSASTLDRGLIVSSRHQEQAEAAGGGAEDSSDEAGGAGGGPRGSSVGQMQNLMTACDDLGKAMESLVVSVVYDSDDEEND 793FD9E5A81008FF q86rt0_caeel protein protein caeel Caenorhabditis elegans RNNCNKSSSTIAYSKSQHEAPKQLLQLRSEIKPLIPLNQPSNFWESSQDSGVLSSLSSSPQQRSGLRSQKLHLTYIEKNKRVRAMIPQQQHYHAFDRPTHYNSRKTSGPPPLMRTPSSGFSSASSSENMFSGLTLSDNENKIHEIMDPSVDVDLDMFLLPDCRYKQPVQPSTSTSRNNVSQISGSSRLNGSTRHVAPIVPKVAMPSELSYANVKRSSGYVDYMPTTYNSNVTSNSSAASVPMSPGTWVRCHYCWESYVKLCQRVANLEPLISCDGPWNWHTLYDMQGRVTCPRLWFAQLDRAGSEMVEQMGHARNVPV B6E8044B998EE0F7 lin36_caeel Protein lin-36 lin-36 F44B9.6 Abnormal cell lineage protein 36 protein protein caeel Caenorhabditis elegans MSEELLSTRPSKRDYNDIEEPEDSHVTVHSVEQDSQHSGEESSTVDALQETEGDVDVIGEDEDEHDIPVMPTVTSSGEVLDESQVTPTKQASSSQPREEIIHGKGESVYSSFPCQVIPETLSRMTRTPPDGEHLEVYRMSNGRLRIYVVDHFKKFSPYSNLTHKPCTVCNRVMKSGEMHLNFPADLDRRRIWANLLGFKYKDILRSKMGPVSFSIAAGPICTEHFAEECFRNHNFNKSAIEAFGVPVAISPDVKTTPSKKSSRVPWVCTVCEFHSCSVVELQTHLLNHTEEMLKKKDNVLDVPEAGFMCPFCRKCTYGYKTISGYRRHLNAGPIHHCHLRRIYEFAKMNCRATELDPAESWDNWTRRNVYVAYHGCEPPANEIVLTPSPTKKAYVQNPEERTKMVHDEEKRKKAVRTLSFVGKEGGTSVNDLNVMQRQVFLQLRREAEINTKAEESAQGTKEQESSQKKHAEEESDDVSELTSHQSPQAPMGSGERRKATRLATSATNSPIKKVAKHEVPATAPSTPAKKRKISHEEEHDPTPESVEREPTVSPNDPRERLRLKERDEQFAKMVQKRSQQVKRLINAKQFKKQEAATKKPRKALAYNLAKGIAATSSTEPEDKVTSSEQTPEPTTSQKFIARNTRSKTKESAVQKVEKPATPVAKPAPVEKEPEERPLKSMLARSFVAGVRPSMAKYQIPLESFTATASLGGGRSLSSGVISRPPTSSSPGGIFSQRVMGAVAQEKGPAKRPSVLSRRPLILSPRKKTSTPRPTLSHHESSPNFSASSPVVVSDEYLIPATDMEVEMVEEVIDSMGNSSSEDVATSSTSSERQPMLTLAEALEMDGSSGTVKDQDMEEISKEMMKDAHYYRAMEDAIKCRTVTKMRADMRLSRHCIRQIEAARARARLFGERTEDYQIFYSNDGAQVLTKKDPKWRELQQQQQQQQQQQEQFPGQGSSDSQQ 0822197B43572514 gpa7_caeel Guanine nucleotide-binding protein alpha-7 subunit gpa-7 R10H10.5 protein protein caeel Caenorhabditis elegans MGHCTSKDQKEGKRLNRRIDEQIKKDQSMSLRIIKLLLLGAGESGKSTILKQMRILHKDGFSQQDLEMIRPVVYSNCIHSMLSILRAMFHLQIEYGEPDRVRDSQLVFATVHANKEELTEELAAAMQRLWHDPGVRECYRRSNEYQIDDSAKYFLDNLPRLSSPNYVPSEQDLLRTRIKTTGITEVLFELKGLTFRVIDVGGQRSERKKWIHCFDNVNAIIFISSLSEYDQTLREDNCTNRMQESLKLFDSICNSPWFADIHFILFLNKKDLFAEKIVRSPLTVCFPEYKGQQNQTECINYIQWKFEQLNRSSQREIYCHHTCATDTNNVQFVLDACLDMIIAKNLKSMGLC 375A1A4D462EFE5E gpa6_caeel Guanine nucleotide-binding protein alpha-6 subunit gpa-6 F48C11.1 protein protein caeel Caenorhabditis elegans MGAGATGLRGARLSPEERANSSKSRAIDRALSKDHTDDLNRFKILLLGTAESGKSTIFKQMRVLHLDGYAKEDALEYLSIIHSNCMEALTQLVDACTAFGINHDITVQEDVNRFEDFKRKLRDPEGLVIPVVIGRCMDRVWHSPSLQLCYDTRRFRFALLDSAKYFMDNIVRLTEDNYVPSIQDIVHCRISTTGINELAFNYKKMDFKMVDVGGQRSERRKWIHCFDNVDMILFIVSMSDYDQLDPEDNKYNRMKQSYEIFKTIVHSDLFRHASIVLFLNKYDVFVEKLKTSPLRRSFKNYEGDNSEESAREFIKKLFRRCITDRHKFFVFETTATDTGNIDLVFGSAVAHIVNENLRSAGLHE 14D594208714F63E q86rt3_caeel protein protein caeel Caenorhabditis elegans FEIMIKPLVIIAVLLVNDVVCPPPLRQQAEQAQAQDNVQHQPATGDAQQGQGQAQNTEQQGEYDGRHPGYQFAYTKYLEEVVKILESDPKFNERLKNMKEEDIKAGNIADHIDDLPQEVFDKLHKAKFDEIERLRKQIEEQIKADGGAHNIKMPDHLDVQELEKFHKEDLRKLIQKTVADMNVMDEQRKDDFKQYEMKKQAEEDHKLAQMTPEEREKAKSEHEESLKRHNDHEKLKHPGSKDQLQEVWEESDHLEKDQYDPKTFFALHDLNGDGFWNDFELESLFQLELEKMYNETNPDDDMKERAEEMYRMREHVMKQIDVNQDRMISMQEFLNDSDNQNSNPPKQEEWEDLGQKKVYTDEELQQFEREYAQKQEQQHPQEAVQQPPQAQQQVHPAQQPIQPVNANPPPVQNAQPPVQQQQQPPQQPPQQPPQQNLPPVHHEPIQDHTKDPTYGI BED77A4D9B41EF74 gpa13_caeel Guanine nucleotide-binding protein alpha-13 subunit gpa-13 F18E2.5 protein protein caeel Caenorhabditis elegans MGCNFSSQSKLQVPEIRASRSITPASQKSEDPYSHIRLLLLGSAESGKTTVLEQVRLLYKQHFTESEYFHRRAFIYHNIFKSIKALCRAMRMSDIQFADPINMGRAQSIIADEHGHYGLFSKDLAEKIKHIWNDKSMQKLYARRSQFNLNDSASYFLNNIDKINMVDYKPSERDLIMAYVPTCGVQNVIFTACNQSFQLFDIGGQKIDRRKWALQYEGIDAIFFCIAISEYDQVMSEDMVTNRLDDALNLLQSISEDPAFATTPIYLFLNEIDVFCEKLSVIPLSKYKPDFKGGDQDDAIDFMENLACEALGKRDRSLYRVYRCIAIDTQMMAELLSTVFKDIAKRKK F0268A48CBC5C4B3 gnao_caeel Guanine nucleotide-binding protein G(o) subunit alpha goa-1 C26C6.2 protein protein caeel Caenorhabditis elegans MGCTMSQEERAALERSRMIEKNLKEDGMQAAKDIKLLLLGAGESGKSTIVKQMKIIHESGFTAEDYKQYKPVVYSNTVQSLVAILRAMSNLGVSFGSADREVDAKLVMDVVARMEDTEPFSEELLSSMKRLWGDAGVQDCFSRSNEYQLNDSAKYFLDDLERLGEAIYQPTEQDILRTRVKTTGIVEVHFTFKNLNFKLFDVGGQRSERKKWIHCFEDVTAIIFCVAMSEYDQVLHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICFPEYSGRQDYHEASAYIQAQFEAKNKSANKEIYCHMTCATDTTNIQFVFDAVTDVIIANNLRGCGLY 8C98245C8E9C48B0 q19955_caeel ags-3 F32A6.4 CELE_F32A6.4 protein protein caeel Caenorhabditis elegans MQDRSCYKLTQEGERLFRMQKYEKGIDLLKKALEVGTDDFSLLSAIYCQLGNAHTMLKDYEQALKFHTYDILVERLLGNKEGEAKSCANLGNIFKMKGAYNDALTFTFKQLDFAEELGDRVLKSRAYYNIATIYVERGRCTKLEAAEEKNDAKNAEATSDFENAAKYFMLNLEMSEKSEDALTMGRCYGSLGNTYYCLGDYDQSIHFHKLRLELSQQYGDRASMRRAHANIANCHALKSNMPLAIQHYKLAYNLAIEIGNKTEEAQMAYSLANALYIGKEVQKAITYFQRHLKIARSLEDISGQLRSYYSLALSFNNLCERRKALYFLVLAKRSSLQVNDTSALTDIDNLLNEILEAGQEDVLVDDIELIIDESADPAPADIEHRELRLTYFQKRNIHDKPVNTPEDPLAEDRYEKEEFFDMLAKLQSKRMNDQRVDASVLSSNLDFRVRQVDTEPDNSSTDGSEVLIDLLLNAQGRRMDDQRAPFLPGLNPNGQIILRRLNTDPGNEELDEHLVEWLMRVQGERLDEQRSELPPIKPEGQEEVDKKKEEDVTAIVMRMQAGRLEDQRAHLPNIPTSKN F61F2B9909A7C617 nh114_caeel Nuclear hormone receptor 114 Y45G5AM.1 nhr-114 protein protein caeel Caenorhabditis elegans MTPQSSPSSSRDHVCLVCQDFASGYHYGVPSCVGCKTFFRRTIMKKQKYICQFEGNCPVDKTIRCACRYCRFEKCLSVGMDRNALQQNRDPIGYTKRTRRPKKELKTTSDCSSDEGASTPPSVSPLQLSPPPISPLLFQAAPLKPRRCILQTLAEREKCANDLRLSEYLPIRSLHEALCSKALLNDTAFLEKWGQPSERHQIFDLRFVNHDDYHYWHERDWFLLTEYAKTFDVFEALDYQDKAELVRHAAITVPVLVQVWNSPDYGPDTIVFPDGAYFDRTPEPTRPAGLNRKKYQMLDLVLKPFRDLQLDATEFAAFKAVTFLNPDADISLPARKLVNNERVRITKQLYGYMAMKDDVDTAIERFARLVLMGTSMSKMACESKEAVWIADFFENIGFSAFARQLFFGDTTSVVAHKL 94400687A542EFD6 g5ee25_caeel Non-specific serine/threonine protein kinase hasp-1 C01H6.9 CELE_C01H6.9 protein protein caeel Caenorhabditis elegans MPPKPRIKVPISPGKKARNNFARRNRQLSSVIITECPIDFPEYEFSKNPALFKSFNDNPEFKPSKKKNKPKPVFPPSPNVSDVEISSDEEDAGQFKVPDADADEEEKIKKIKEAFDSLDDVSLEVFNNDGIRVKIENGKHIIHDKQPEEAWRPGIREYHDGNFPMMNKPAKKIDFAKKMEQRQKKPVKQVPEMNSKANQVQCPTNYASFCGSILADHMRQNKKASLAAPSLFRVFGTPQRSKMIVPAKHVQCQDERLAIYSYTPIRVNKTAKQLDDTIGSIVFSPKTQNASTPIEKQTAGRRPKSFPVFDVSLNDSCENITKKEEQIAQKSANSDQKETTINNIPIEEEYSGRVHESSLAGSIQQPQQDLEETAISENRLSHSTLKTTPIESRNESHQNSKIMTQQVSDSEDVEDVTFNRKAETSVTELLHEEDEHERCSDLNLEESKYSKKRQRTKSPETMCQGMSTVMTMQDDQDDLEALFEIEKENEIRKRTTLQPQQRQRDRESRVSRLSVMSAASSRHDSINSAMEEMSLQQFLEDTMGEEFGKTQYSESRAESRNIPTGMTIHNEDPSILPFYLEDLTSEIDPSPMMQLLHVVGQKESKTWDSLPKSALDGRRVKKLGEGAYGEVFSTIWDGKPVAIKIVPFEKDGCNRQYFGEYHSEEMQTSDVVLPEVIVMKELSALRDEDAWNSTPNFIEMISAEVVMGKYPKGLLSAWDSYDKLKESENTRPDVYSSIDQNFILFVSANGGIALEDFVLESENELFSIIHQLVLSMNAAEAALEFEHRDLHLGNVLIDRNGVKELYYTVHGQKVPLSTHGIKVNIIDFTLSRISKGATTVYWDLENDPAIFEGQDDPQFEVYREMRKNCKSNWKKFSRRTNLMWIVYIANRLIDTKICPKGLLTEKRRMELKVLFDRFAEFGSCGESLTNEEFFSDFYEGPIGMSTTRQ 7D0D862B873D86E9 gbas1_caeel G-protein alpha subunit activating protein gbas-1 gbas-1 F59H5.1 protein protein caeel Caenorhabditis elegans MRSVRSSSRTPKPVKRFVFDEDEDLEEIDLDEVDNADFEREDDEEEVLSEPSESPYTSTPKSSKRVNKTRGTKDFFKKDESLQLFRFVLNECRSQKPGRVGRVAKKRVGVNSMKYWERYKREIQGYRLPKQYRYHYSFYSKCFYKVLGLTPEEKVDLYYACEMPVVTDAEKQWLVEQFHVEFDEFGVIIGSDVCTHWDEEHSDSEDDSGKKEEKAREVSRYTEYHDDMMWKFIVDKISEGAQPIIDKHPIWDEFVKLNEENDVISKKSGRNHYDRFRRILVPNLHFMPYDDFTKAVLYERLEYPIPEEYRKILFTTTGADINESGFIEYLPPSTIHQISPIVPIPCHKSNPKFSQLKEPKDLILWSERKKFTPREDSQIWEFVRRKCVDSAGIFVKNDVLRGRGTLFFKDFRNTERKYESITQRFVVLRKLIMDTDYSLKQKLEIYYAISQPVDEDALDAFKSIACLVLNPDGTIRFAISKSFLIGRISDEPAKLEAENYSYVYDLFIFNETFGTAENPEPLCSVSQNRAEKFMLVSQLVFRFISRFEALEDRRIAWITPNAQVAPKEPVPAPSKKKSAFEAYQSSPQTFDTIQRFSTKRPFFCGDNFQIPPKKPFLAEEDVKLEPMEYENSEQIVENAEIKLEPAEELLDAETVTVEEFLMNSYSTAAPSTSTAPAPPKAPVTAPPAPQKSAQLLGKIDFAIGKMRENFDRFLQFAQQNSADLTVVQRYRYDAQMQQMTEKFTKDVSKVLSGDSIKR 7A09454A270DD59F q86rt5_caeel protein protein caeel Caenorhabditis elegans DKDFYNDVPLAEDVLEPGQSLGNSESMKFDYVVIQPHVRPHQQIPTSSYSRRKSPQSRETEAIVRTYPLSPKRIVQQHRMPQKNNPDQQHQMNEVKKEVNPFGRQGVLVEVEPSPSYAQSNTKIYKMVSAHRSATPQPAVTVASSRRLVHMPHRTNSLVYDSMPELIDSSNMPSEPPKKKIHLEVGHRNSEMVGVSTSSNAPCLPKEILTDGVPIADDEIILEADGECKIGSGMLLESQQSSSQNHEMDMPSTSMDHYHHQDIDDGGVGDDIEQQVVVGGPSDEMAIQYDEDLAFQQHINSVLNRLSDDEKSVMKFNMQKIILDARFGLGTARNMLKHDEMLEVESHVEIDPNHEVPEEI 7642BC626B956206 nhr22_caeel Nuclear hormone receptor family member nhr-22 nhr-22 K06A1.4 protein protein caeel Caenorhabditis elegans MSTDLLYEYFYPPTDLFKNTFEDVPPSPESLDVGDSLGSSPSYDLGFQPSFDIDFCIWKEGSSSPPPESNHLPEIVNKASTSPRGMPSPLTDSRSCHVCSSPTANTLHFGGRSCKACAAFFRRSVSMSMTYECIGTGDDTNPCRTHYELRMICRHCRFIKCLDAGMRRELVQARKEETRVAKRRSKGLVVSKKEDDDVESSYDEYVNTYTNVQDSSPKMESGINEMTIPESYLSPDPSSSQPLDMTVTPPPLHRSTPSILLTPATGDRMHCQRVLSNSPPFDIHQASTSHAGFIQHVQFYPVVEVENKIFELVDHYVRTEASLNDRRKIMYTDTQIRDVFDTTCECPYENHQLKPFNYKSFCGFVKHDFVMILDYVNQFPEFQALHKNDKNVVYRMACAVDSMLASAYYSYKVGIEKERLILFNGDYINMNPIPISGDEPGAGTEFQTPQEHEKYKTLMPLKLKQYFDLAIPFARLEVSFEEYVLLKALIIWQISNYRLLEEGRAICARQRDTIVQALHKVVEERGDEDPAIRVGQLLLSMSYITEQVQAMTNSYLVMTFFDVVSCDSIMYDLLSFRDD C76F1646819ED4CC q86rs9_caeel protein protein caeel Caenorhabditis elegans DWIYSWKDSIFYGMCSCSGSPSYHEKDVPHPHDRLDMPLQLKAYRRNSLNAEGYYRDLERMHERGLFTTGINYNAEKSEDFLNMIERMQSNRLDDQRCEMPERTHNPTSGHQNEQTHQKTNGSAVHNQLTRNIMNEVLTKVGPYPQIVLPSNGFWMDGVNQQHHMDDQVNNMNVNSCARFKLETDETSHCYRRHFFGREHHDFFANDPIVGPLVLSVRTEVISSCDHFRIILRTRKGTIHEIVSATGLADRPSASRMAKLLCEEITTEQFSPVAFPGGSELIVQYDEHVLTNTYKFGVIYQKGGQTTEEQLFGNPHGSPAFDEFLSMIGDSVQLNGFQKYRGGLDTAHNQTGHQSVFSEFKNREIMFHVSTMLPYTIGDAQQLQRKRHIGNDIVAIIFQEANTPFAPDMIASNFLHAYVVVQPIDALTDRVRYRVSVAARDDVPFFGPTLPTPSIFKRGQDFRNFLLTKLINAENAAYKSSKFAKLAERTRSSLLDGLHATLRERAEFYATPLLESTSSGGESAATTSSSSNSYGGGILSSVKKAFIGRSRSVSQEASHVPHRAATINVTSRPKKSISSTSSSTSARTHSPIRDEEVVKPYRKEWEISSQESPDNEHDSDTGMESMSSTEMSGQTRASSCTFCVDDFHVAANHQSSDAKRLETLCVDVTRLQNEKHDLLRQNVSCKTDIKKLKDRQSVLSEELERANDEISRLRRMLKKPSNSDMAPVHQHFERSYSDVSV 160DAA841B41D970 gpa_6-q86rt0 1 7 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain undetermined undetermined sequence position undetermined physical association physical association Table 2 gpa_7-nhr22 1 16 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 6 unspecified role unspecified role bait bait physical association physical association Table 2 gpa_13 1 9 unspecified role unspecified role bait bait 12 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 gpa_13-dys1 1 3 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 9 unspecified role unspecified role bait bait physical association physical association Table 2 goa_1-q86rt5 1 15 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait physical association physical association Table 2 goa_1-c01h6.9 1 10 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 goa_1-lin36 1 5 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait physical association physical association Table 2 goa_1-f59h5.1 1 14 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 10 unspecified role unspecified role bait bait physical association physical association Table 2 goa_1-f32a6.4 1 10 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 goa_1-rapgap 1 10 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 goa_1-q86rs9 1 10 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 goa_1-rapgap-1 2 10 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey physical association physical association Fig 1 goa_1-f32a6.4-1 2 11 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 1 goa_1-f59h5.1-1 2 14 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 1 gpa_7-nhr22-1 2 16 unspecified role unspecified role prey prey 6 unspecified role unspecified role bait bait physical association physical association Fig 1 goa_1-c01h6.9-1 2 10 unspecified role unspecified role bait bait 13 unspecified role unspecified role prey prey physical association physical association Fig 1 gpa_13-1 2 12 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-13. gpa_6-q86rt0-1 2 7 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey physical association physical association Fig 1 goa_1-lin36-1 2 10 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey physical association physical association Fig 1 goa_1-q86rt5-1 2 15 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 1 goa_1-q86rs9-1 2 8 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 1 rapgap-goa_1 2 17 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GOA-1. ags_3-goa_1 2 10 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait physical association physical association Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GOA-1. q9tzi4-goa_1 2 10 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association Fig 1 lin_36-goa_1 2 5 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Fig 1 lin_36-lin36 2 5 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey physical association physical association Fig 1 q86rt0-nhr_22 2 16 unspecified role unspecified role prey prey 4 unspecified role unspecified role bait bait physical association physical association Fig 1 q86rs9-q86rs9 2 17 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association Fig 1 goa_1ql-ags_3 2 10 unspecified role unspecified role bait bait P51875:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 17:22:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln205leu' Tue Jun 30 19:14:39 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln205Leu' 11 unspecified role unspecified role prey prey physical association physical association Fig 1 Only two (AGS3.1 and Rap1GAP) out of the seven candidates, interact with the constitutively active GTPase-deficient mutant of GOA-1, as Bait. goa_1-rapgap 2 17 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait P51875:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 19:20:13 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln205leu' Tue Jun 30 18:09:19 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln205Leu' physical association physical association Fig 1 Only two (AGS3.1 and Rap1GAP) out of the seven candidates, interact with the constitutively active GTPase-deficient mutant of GOA-1, as Bait. gpa_13-nhr_114 2 12 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait Q9XTB2:p.Gln205Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 17:46:28 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln205leu' Tue Jun 30 16:41:53 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln205Leu' physical association physical association Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-13. The mutation has been entered for the GPA-13 constitutively active GTPase-deficient mutant as "gln205leu" - as the most likely mutation site, because the actual mutation site is not stated in this paper. gpa_7-nhr_22 2 6 unspecified role unspecified role bait bait Q21917:p.Gln203Leu mutation mutation certain certain sequence position certain certain certain sequence position certain Q L Wed May 02 14:53:58 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'gln203leu' Tue Jun 30 19:25:07 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln203Leu' 16 unspecified role unspecified role prey prey physical association physical association Fig 1 The interaction also occurred with the constitutively active GTPase-deficient mutant of GPA-7.