mpidb The Microbial Protein Interaction Database Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. J. Bacteriol. (0021-9193) 2008 imex curation Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. 04-Feb-2013: Contacted by IntAct-Help. Only protein-protein interactions helpy Helicobacter pylori Campylobacter pylori anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. Accepted 2013-JAN-10 by ORCHARD 04-Feb-2013: Contacted by IntAct-Help. J. Bacteriol. (0021-9193) 2008 Only protein-protein interactions imex curation Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. Protein subassemblies of the Helicobacter pylori Cag type IV secretion system revealed by localization and interaction studies. J. Bacteriol. (0021-9193) 2008 imex curation Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. 04-Feb-2013: Contacted by IntAct-Help. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Kutter S., Buhrdorf R., Haas J., Schneider-Brachert W., Haas R., Fischer W. Accepted 2013-JAN-10 by ORCHARD 04-Feb-2013: Contacted by IntAct-Help. J. Bacteriol. (0021-9193) 2008 Only protein-protein interactions imex curation e0wk31_helpx cagY HP527 protein protein helpx Helicobacter pylori Campylobacter pylori MNEENDKLETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDGDKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDGDKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETIKANHFEDSSKESKESSDHHLDNSTETETNFDEYKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNECLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQNDILAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECGKLLTPEARKLLEQQVLDCLKSAKTDEERKKCLKDLPKDLQKKVLAKESVKAYLDCVSQAKNEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQAKTEAEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEAKKKLEEAKKSVKAYLDCVSQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEAKKLLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSRARNEKEKKECEKLLTPEARKLLEEAKESLKAYKDCLSQARNEEERKACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKNCLSQARNEEERKACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSDLIQEIQNKRTQSKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERALILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKTEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPVMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVIASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN AF7BBC165FEA98C0 e0wih3_helpx cagY HP0527 protein protein helpx Helicobacter pylori Campylobacter pylori MNEENDKLETSKKTQQHSPQDLSNEETTEANHFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEDDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETTEANHFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEDDQENNGYQEETQMDLIDDETSKKTQQHSPQDLSNEETTEANRFEDSSKESKESSDHHLDNSTETKTNFDEYKSEETQTQMDSGGNETSESSNLADKLFKKARKLVDNKRPFTQQKNLDEEIQEPNEEYDQENNGYQEETQMDLIDDEASKKTQQHSPQDLSNEETTKANRFEDSSKESKESSDHHLDNSTETKTNFDGEKSEEITNDSNDQEIIKGSKKKYIIGGIVVAVLIVIILFSRSIFHYFIPLEDKSSRFSKDRNLYVNDEIQIRQEYNRLLKERNEKGNMIDKNLFFNDDPNRTLYNYLNIAEIEDKNPLRAFYECISNGGNYEECLKLIKDKKLQDQMKKTLEAYNDCIKNAKTEEERIKCLDLIKDENLKKSLLNQQKVQVALDCLKNAKTDEERNECLKLINDPEIREKFRKELELQKELQEYKDCIKNAKTEAEKNKCLKGLSKEAIERLKQQALDCLKNAKTDEERNECLKNIPQDLQKELLADMSVKAYKDCVSKARNEKEKKECEKLLTPEAKKKLEQQVLDCLKNAKTDEERKKCLKDLPKDLQSDILAKESVKAYKDCVSRARNEKEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSKARNEKEKKECEKLLTPEARKKLEEAKKSVKAYLDCVSQARTEAEKKECEKLLTPEARKLLEQEALDCLKNAKTEAEKKKCIKDLPKDLQKKVLAKKSVKAYLDCVSQARTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSQARTEAEKKECEKLLTPEAKKLLEEAKESLKAYKDCVSQARTEAEKKECEKLLTPEAKKLLEEEAKESVKAYLDCVSRARNEKEKKECEKLLTPEAKKKLEEAKKSVKAYLDCISQAKTEAEKKECEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKKECEKLLTPEARKFLEQQALDCLKNAKTEAEKKRCVKDLPKDLQKKVLAKESVKAYLDCVSRARNEREKQECEKLLTPEAKKLLEEAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKQVLSCLEKARNEEERKACLKNIPKDLQKNVLAKESLKAYKDCLSQARNEEERRACEKLLTPEARKLLEQEVKKSVKAYLDCVSRARNEKEKQECEKLLTPEARKFLAKELQQKDKAIKDCLKNADPNDRAAIMKCLDGLSDEEKLKYLQEAREKAVLDCLKTARTDEEKRKCQNLYSGLIQEIQNKRTQSKQNQLSKTERLHQASECLDNLDDPTDQEAIEQCLEGLSDSERVLILGIKRQADEVDLIYSDLRNRKTFDNMAAKGYPLLPMDFKNGGDIATINATNVDADKIASDNPIYASIEPDITKQYETEKTIKDKNLEAKLAKALGGNKKDDDKEKSKKSTAEARVESNKIDKDVAETAKNISEIALKNKKEKSGEFVDENGNPIDDKKKAEKQDETSPVKQAFIGKSDPTFVLAQYTPIEITLTSKVDATLTGIVSGVVAKDVWNMNGTMILLDKGTKVYGNYQSVKGGTPIMTRLMIVFTKAITPDGVIIPLANAQAAGMLGEAGVDGYVNNHFMKRIGFAVVASVVNSFLQTAPIIALDKLIGLGKGRSERTPEFNYALGQAINGSMQSSAQMSNQILGQLMNIPPSFYKNEGDSIKILTMDDIDFSGVYDVKITNKSVVDEIIKQSTKTLSREHEEITTSPKGGN F4BA98E772EE434D e0wi24_helpx cagH HP541 protein protein helpx Helicobacter pylori Campylobacter pylori MAGTQAIYESSSAGFLSEISSIISSTSGVAGPFAGIVAGAMSAAIIPIVVGFTNPQMTAIMTQYNQSIAEAVSMPMKAANQQYNQLYQGFNDQSMAVGNNILNISKLTGEFNAQGNTQSAQIGAVNSQIASILASNTTPKNPSAIEAYATNQIAVPSVPTTVEMMSGILGNITSAAPKYALALQEQLRSQASNSSMNNTADSLDSCTALGALVGSSKVFFSCMQISMTPMSVSMPTVYAKYQALATNALTSGVNPMTTPACPIGDKVLAVYCYAEKVAEILREYYIEFVKNNTNLLQNASQMILGQSGLATSTYDTQAISNISSLYNYNIIANKSFLKSHLTYLDYIKDKLKGQKDSYLTERVQTKIIVK B20D5BAD9D4C9947 e0wi21_helpx cagN HP538 protein protein helpx Helicobacter pylori Campylobacter pylori MKSIFKKLGSVALYSLVIYGGLNAINTALLPSEYKKLVALGFKKITTLYQRHDDKEITKEEKEFATNALREKLRNDRARAEQIQKNIEAFEKKNNSSVQKKAAKHRGLQELNETNANPLNDNPNGNSPTETKSNKDDNFDEMINKVNESFVKPADPLVPDKWRTPEIEIIINECIISSNDYDGLRKCLIKDIKDQKILAPLLEKIQEIETENNKFSRQHLSGLKLALNNSNNRTFLIASCAICEKRKKEMEQENNYQDTTNASEFGATDTKENEAKDATSSNNRSKSELPNSVINQIEQSIAHGKNSDPNY B5D5B752E42B2369 e0wif9_helpx cagV HP0530 HP530 EC548_05175 protein protein helpx Helicobacter pylori Campylobacter pylori MLGKKNEEVLIDENLVGGVIALDRLAKLNKANRTFKRAFYLSMALNIAAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSDARQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQFVDKVRAEAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFARGNSSQENLIINPFGFKVFDIQITDLQNEQTVSEILRKIKEVESKNKALKK 352061FA07CB5A30 e0wi15_helpx cagT HP532 protein protein helpx Helicobacter pylori Campylobacter pylori MKLRASVLIGVAILCLILSACSNYAKKVVKQKNHVYTPVYNELIEKYSEIPLNDKLKDTPFMVQVKLPNYKDYLLDNKQVVLTFKLVHHSKKITLIGDANKILQYKNYFQANGARSDIDFYLQPTLNQKGVVMIASNYNDNPNNKEQPQTFDVLQGSQPMLGANTKNLHGYDVSGANNKQVINEVAREKAQLEKINQYYKTLLQDKEQEYTTRKNNQREILETLSNRAGYQMRQNVISSEIFKNGNLNMQTREEEVREKLQEERENEYLRNQIRSLLSGK 42F7CFFA8CB4EB7A a4gmu0_helpx HP0528 cag8 protein protein helpx Helicobacter pylori Campylobacter pylori MEQAFFKKIVNCFCLGYLFLSGVIEAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWNIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEETIKQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK F5502A906D217FC8 e0wif7_helpx cagX HP0528 HP528 protein protein helpx Helicobacter pylori Campylobacter pylori MEQAFFKKIVGCFCLGYLFLSSVIEAAAPDIKNFNRGRVKVVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSEFIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEETVKQRAKDKINIKTDKPQKSPEDNSIELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEGELKKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRNYNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMTNSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVRDK D1FC5CB9EF22FEA7 e0wk28_helpx cagBeta HP524 protein protein helpx Helicobacter pylori Campylobacter pylori MEDFLYNTLYFIENYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILLLSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITFFVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPTRSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVYIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQIDTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNERDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTMFFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLKVLSPATRNMWNNFKTMGGARETYSSVQGVYTSAFAPYNNAMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLETFVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRSIDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQATFYDDLQAAKTRGELSYDKSLVPVGSSEL 97A2A05FC8195BD4 a0fds9_helpx HP0539 cag18 AEY55_04700 CV726_04970 NCTC12823_00667 protein protein helpx Helicobacter pylori Campylobacter pylori MKTLVKNTISSFLLLSVLMAEDITSGLKQLDNTYKETNQQVLKNLDEIFSTTSPSANNEIGQEDALNIKKAAIALRGDLALLKANFEANELFFISEDVIFKTYMSSPELLLTYMKINPLDQNTAEQQCGISDKVLVLYCEGKLKIEQEKQNIRERLETSLKAYQSNIGGTASLITASQTLVESLKNKNFIKGIRKLMLAHNKVFLNYLEELDALERSLEQSKRQYLQERQSSKIIVK CCA892917A40ECD2 e0wi14_helpx D2C82_03050 BGL56_05570 cagU HP531 protein protein helpx Helicobacter pylori Campylobacter pylori MNDTTEHHGSNPLNAPPPSNSQSNDLLNLLDSLYPKGSLGEQRFHEALKNQEELKNILIEIEKLPQEKRYELLMQIGQAKQRIMEAYAHSFLGYIGGLEHLLGLCMGGIFVLFAIYFVFLRTSKNTELVESLKTRLKLQYFYYAFGVGAVLFFGLETIRSIYELYILGIGSTNDKVLFVLKNICFIGMGYLIYKVIKVIGIKNFINGLFASKKQGGAE 441A0AB71EC80BAF a0fds8_helpx HP0537 cag16 cagM AEY52_04155 AEY53_01525 ECC33_03325 protein protein helpx Helicobacter pylori Campylobacter pylori MLAKIVFSSLVAFGVLSANVEQFGSFFNEIKKEQEEVAAKEDALKARKKLLNNTHDFLEDLVFRKQKIKELMDHRAKVLSDLENKYKKEKEALEKETRGKILTAKSKAYGDLEQALKDNPLYKKLLPNPYAYVLNQETFTKEDKERLSYYYPQVKTSSIFKKTTATTKDKAQALLQMGVFSLDEEQNKKASRLALSYKQAIEEYSNNVSNLLSRKELDNIDYYLQLERNKFDSKAKDIAQKATNTLIFNSERLAFSMAIDKINEKYLRGYEAFSNLLKNVKDDVELNTLTKNFTNQKLSFAQKQKLCLLVLDSFNFDTQSKKSILKKTNEYNIFVDSDPMMHDKTTMQKEHYKIFNFFKTVVSAYRNNVAKNNPFE 8B1E2C293A1578F9 e0whx5_helpx Type IV secretion system protein D2C88_07850 F7214_07700 G3M67_01650 G3M68_02165 virB11 BB390_07385 BB399_06580 BB400_06565 BB408_03415 BB409_06940 BB413_00305 BB414_01925 BB425_07095 BB432_04770 BB447_03415 BB457_02875 BB458_07415 BB459_01845 D2C71_01285 D2C72_01830 D2C73_05755 D2C77_01800 D2C79_04640 D2C81_06585 D2C82_03020 D2C83_06175 D2C87_02690 G3M69_06130 EPC73_04595 EPC76_07865 EPC81_06110 EPC84_06070 B0X24_06635 B0X38_06500 B0X41_06920 B0X44_06825 B0X46_00385 B0X55_08345 B0X66_06525 cagAlpha BB456_03380 BB450_01410 BB464_01490 NCTC13094_00155 BB465_01035 DD741_03450 DD763_02555 DD767_02220 DD773_01955 DD774_02235 DD776_02915 DD794_03195 BB467_03295 BB468_07040 BB479_00320 BB482_02255 BB483_03555 BCM300_00547 BGL56_08125 BGL58_06750 BGL61_01890 BGL62_00535 BGL69_06470 BGL71_04855 BGL73_03525 BGL83_04980 BGL85_01790 BZK17_00420 BZK18_00380 BZK20_03360 BZK22_01120 BZK23_01125 BZK25_05690 BZK27_07230 C2R50_00720 C2R69_03570 C2R71_01915 C2R76_06890 C2R81_06955 C2R88_00960 C2R92_04375 HP0525 HP525 HPY1198_03775 cagalpha F7190_06260 F7195_05360 F7212_07765 EGW01_00990 EC516_05795 EC549_02620 D2C86_05370 F7204_05345 EGV97_03120 F7221_05960 F7223_05905 F7209_03795 protein protein helpx Helicobacter pylori Campylobacter pylori MTEDRLSAEDKKFLEVERALKEAALNPLRHATEELFGDFLKMENITEICYNGDKVVWVLKNNGEWQPFDVRNKKAFSLSRLMHFARCCASFKKKTIDNYENPILSSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKTTYIKSIMEFIPKEERIISIEDTEEIVFKHHKNYTQLFFGGNITSADCLKSCLRMRPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLANMSSSNSAARNIKFESLIEGFKDLIDIIVHINHHKQCDEFYIKHR 097A0082C706C9E3 caga_helpy Cytotoxicity-associated immunodominant antigen 120 kDa protein CAG pathogenicity island protein 26 cai HP_0547 cagA cag26 protein protein helpy Helicobacter pylori Campylobacter pylori MTNETIDQTRTPDQTQSQTAFDPQQFINNLQVAFIKVDNVVASFDPDQKPIVDKNDRDNRQAFDGISQLREEYSNKAIKNPTKKNQYFSDFIDKSNDLINKDNLIDVESSTKSFQKFGDQRYQIFTSWVSHQKDPSKINTRSIRNFMENIIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQKFMGVFDESLKERQEAEKNGGPTGGDWLDIFLSFIFNKKQSSDVKEAINQEPVPHVQPDIATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALSSVLMGSHNGIEPEKVSLLYAGNGGFGDKHDWNATVGYKDQQGNNVATLINVHMKNGSGLVIAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIRNKVDFMEFLAQNNTKLDNLSEKEKEKFQNEIEDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFNNGDLSYTLKDYGKKADKALDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGATNGVSHLEAGFNKVAVFNLPDLNNLAITSFVRRNLENKLTAKGLSLQEANKLIKDFLSSNKELAGKALNFNKAVAEAKSTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYTQNLKGIKRELSDKLEKISKDLKDFSKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKVTDKVDNLNQAVSVAKAMGDFSRVEQVLADLKNFSKEQLAQQAQKNEDFNTGKNSELYQSVKNSVNKTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFNNNNNGLKNSTEPIYAKVNKKKTGQVASPEEPIYTQVAKKVNAKIDRLNQIASGLGGVGQAAGFPLKRHDKVDDLSKVGLSASPEPIYATIDDLGGPFPLKRHDKVDDLSKVGRSRNQELAQKIDNLNQAVSEAKAGFFGNLEQTIDKLKDSTKKNVMNLYVESAKKVPASLSAKLDNYAINSHTRINSNIQNGAINEKATGMLTQKNPEWLKLVNDKIVAHNVGSVSLSEYDKIGFNQKNMKDYSDSFKFSTKLNNAVKDIKSGFTHFLANAFSTGYYCLARENAEHGIKNVNTKGGFQKS DIP protein P55980 original sequence version: 51 DIP protein P55980 original sequence version: 69 B05C3F2CCC4444F4 e0wi26_helpx cagF HP543 protein protein helpx Helicobacter pylori Campylobacter pylori MKQSLREQKLLKILENDVLTILDSFSNYLFELKEELDFIEEEMEGEITEQNLTALYDFSNFLEDHVNVFYENVLNIDDVKTEHLYSGLIDSLNANLHFVKSFLSNQDLDFRFFKEINDGQDPQKTLSRLIPLQSGKNDANSFKANNSFVSLVYVYAYFMLETIKQSYRILRLLEKPINNNISEDMQSDIENFFVQANFLEYYVQNKIYPTNHAYDFTHLIMDSIIPNWIQIDMSVEAKKKELFEKYFQNIDEVTNKMLDQENQNKNSD 5E32495DB4633088 cagalpha-cagalpha 2 15 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 caga-cagy 2 16 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 caga-cag22-1 2 17 unspecified role unspecified role prey prey 16 unspecified role unspecified role bait bait physical association physical association Table 2 cag22-cagf-1 2 17 unspecified role unspecified role bait bait 9 unspecified role unspecified role prey prey physical association physical association Table 2 cag22-cagf 2 16 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association Table 2 cagh-cagbeta 2 11 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 5 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 36 38 physical association physical association Table 2 cag18-cagbeta 2 11 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 12 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 41 43 physical association physical association Table 2 cag16-cag16 2 14 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey physical association physical association Table 2 cag12-cagt 2 8 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 11 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 cagu-caga 2 16 unspecified role unspecified role prey prey 13 unspecified role unspecified role bait bait physical association physical association Table 2 cag10-cagv 2 6 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 7 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 57 59 physical association physical association Table 2 cag8-cagx 2 10 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 14 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 62 64 physical association physical association Table 2 cag7-cagf 2 17 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 caga-caga 2 16 unspecified role unspecified role prey prey 16 unspecified role unspecified role bait bait physical association physical association Table 2 cagx-cag16 1 3 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey 14 unspecified role unspecified role prey prey association association Fig 6A cagbeta-cagy-3 2 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 11 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 cagy-cagf 2 17 unspecified role unspecified role prey prey 4 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 cagy-cagn 2 4 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 6 unspecified role unspecified role prey prey physical association physical association Table 2 cagy-cagy 2 4 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 94 92 physical association physical association Table 2 cagy-cagy-1 2 4 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 99 97 physical association physical association Table 2 cag16-cagx 2 10 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 14 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 cagn-cagy 2 6 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 cagy-cag16 1 8 unspecified role unspecified role prey prey 10 unspecified role unspecified role prey prey 3 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey association association Fig 6B cag16-cagt 1 10 unspecified role unspecified role prey prey 8 unspecified role unspecified role prey prey 3 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait association association Fig 6C cag16-cagx-1 1 10 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association Fig 7A Interaction observed in CagT and CagY -/- cells cagx-cag16-1 1 10 unspecified role unspecified role bait bait 14 unspecified role unspecified role prey prey physical association physical association Fig 7A Interaction observed in CagT and CagY -/- cells cagx-cag16-2 1 3 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association Fig 7B Interaction observed in CagM and CagT -/- cells cagy-cagx 1 10 unspecified role unspecified role prey prey 3 unspecified role unspecified role bait bait physical association physical association Fig 7B Interaction observed in CagM and CagT -/- cells cag16-cagy 1 10 unspecified role unspecified role ancillary ancillary 3 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait association association Fig 7C cag16-cagt-1 1 8 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association Fig 7D Interaction observed in CagX and CagY -/- cells cagx-cagt 1 8 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait 14 unspecified role unspecified role ancillary ancillary association association Fig 7E