InnateDB InnateDB Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells. Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells. Nat. Immunol. (1529-2908) 2010 imex curation Cardone J., Le Friec G., Vantourout P., Roberts A., Fuchs A., Jackson I., Suddason T., Lord G., Atkinson JP., Cope A., Hayday A., Kemper C. claudia.kemper@kcl.ac.uk orchard Only protein-protein interactions Curated by: InnateDB - a knowledge resource for innate immunity human-t-cell Homo sapiens t-cell Peripheral blood T-lymphocytes anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Cardone J., Le Friec G., Vantourout P., Roberts A., Fuchs A., Jackson I., Suddason T., Lord G., Atkinson JP., Cope A., Hayday A., Kemper C. claudia.kemper@kcl.ac.uk Accepted 2011-APR-07 by ORCHARD Nat. Immunol. (1529-2908) 2010 orchard Only protein-protein interactions imex curation Curated by: InnateDB - a knowledge resource for innate immunity stk39_human STE20/SPS1-related proline-alanine-rich protein kinase SPAK DCHT Serine/threonine-protein kinase 39 STK39 protein protein human Homo sapiens Human MAEPSGSPVHVQLPQQAAPVTAAAAAAPAAATAAPAPAAPAAPAPAPAPAAQAVGWPICRDAYELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCQTSMDELLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLEEAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLRNSRKELNDIRFEFTPGRDTADGVSQELFSAGLVDGHDVVIVAANLQKIVDDPKALKTLTFKLASGCDGSEIPDEVKLIGFAQLSVS 35E68F400A38A861 mcp_human Membrane cofactor protein MCP MIC10 TLX Trophoblast leukocyte common antigen CD46 protein protein human Homo sapiens Human MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHSVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTDETHREVKFTSL DIP protein P15529 original sequence version: 143 85FE0CF100EA703E cd46-stk39-1 1 2 unspecified role unspecified role prey prey 3 unspecified role unspecified role bait bait physical association physical association Fig. 4B Ab used to IP mcp detected isoforms BC1, BC2, C1, C2. See Xref to Uniprot under mcp. anti-CD46 anti-CD3