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  <entry>
    <source releaseDate="2022-02-04">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>The cardiac troponin C mutation Leu29Gln found in a patient with hypertrophic cardiomyopathy does not alter contractile parameters in skinned murine myocardium.</fullName>
        </names>
        <bibref>
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          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">The cardiac troponin C mutation Leu29Gln found in a patient with hypertrophic cardiomyopathy does not alter contractile parameters in skinned murine myocardium.</attribute>
            <attribute name="journal" nameAc="MI:0885">Basic Res. Cardiol. (0300-8428)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2009</attribute>
            <attribute name="author-list" nameAc="MI:0636">Neulen A., Stehle R., Pfitzer G.</attribute>
            <attribute name="remark-internal">suggested by panni</attribute>
            <attribute name="contact-email" nameAc="MI:0634">Axel.Neulen@uni-koeln.de</attribute>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>phosphatase assay</shortLabel>
            <fullName>phosphatase assay</fullName>
          </names>
          <xref>
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        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Neulen A., Stehle R., Pfitzer G.</attribute>
          <attribute name="remark-internal">suggested by panni</attribute>
          <attribute name="contact-email" nameAc="MI:0634">Axel.Neulen@uni-koeln.de</attribute>
          <attribute name="journal" nameAc="MI:0885">Basic Res. Cardiol. (0300-8428)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2009</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>pp1a_mouse</shortLabel>
          <fullName>Serine/threonine-protein phosphatase PP1-alpha catalytic subunit</fullName>
          <alias type="gene name" typeAc="MI:0301">Ppp1ca</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ppp1a</alias>
        </names>
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          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P62137" version="SP_42" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_114074.1"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
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        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MSDSEKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIRYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK</sequence>
        <attributeList>
          <attribute name="crc64">8FBFD158A52282E0</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>tnnc1_mouse</shortLabel>
          <fullName>Troponin C, slow skeletal and cardiac muscles</fullName>
          <alias type="gene name" typeAc="MI:0301">Tnnc1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Tncc</alias>
        </names>
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          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
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        </interactorType>
        <organism ncbiTaxId="10090">
          <names>
            <shortLabel>mouse</shortLabel>
            <fullName>Mus musculus</fullName>
            <alias type="synonym" typeAc="MI:1041">Mouse</alias>
          </names>
        </organism>
        <sequence>MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKMMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE</sequence>
        <attributeList>
          <attribute name="crc64">34DCC903C157A312</attribute>
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      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>ppp1ca-tnnc1</shortLabel>
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        <experimentList>
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            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>enzyme</shortLabel>
                <fullName>enzyme</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0501" refType="identity" refTypeAc="MI:0356"/>
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            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
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            </experimentalRoleList>
          </participant>
          <participant id="6">
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            </xref>
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>enzyme target</shortLabel>
                <fullName>enzyme target</fullName>
                <alias type="go synonym" typeAc="MI:0303">substrate</alias>
                <alias type="synonym" typeAc="MI:1041">substrate</alias>
              </names>
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                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0502" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>neutral component</shortLabel>
                  <fullName>neutral component</fullName>
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                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0497" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>dephosphorylation</shortLabel>
            <fullName>dephosphorylation reaction</fullName>
            <alias type="synonym" typeAc="MI:1041">dephosphorylation</alias>
          </names>
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            <secondaryRef db="resid" dbAc="MI:0248" id="AA0036" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0037" refType="see-also" refTypeAc="MI:0361"/>
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            <secondaryRef db="resid" dbAc="MI:0248" id="AA0039" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="resid" dbAc="MI:0248" id="AA0222" refType="see-also" refTypeAc="MI:0361"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="go" dbAc="MI:0448" id="GO:0016311" refType="see-also" refTypeAc="MI:0361"/>
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        </interactionType>
        <attributeList>
          <attribute name="figure legend" nameAc="MI:0599">F3</attribute>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>