UniProt UniProt http://www.uniprot.org Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways. Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways. RNA (1355-8382) 2007 mimix curation van Dijk EL., Schilders G., Pruijn GJ. G.Pruijn@ncmls.ru.nl mgt human Homo sapiens Human density sedimentation cosedimentation through density gradient density sedimentation western blot western blot Immuno blot Immuno blot van Dijk EL., Schilders G., Pruijn GJ. G.Pruijn@ncmls.ru.nl Accepted 2011-APR-06 by MGT RNA (1355-8382) 2007 mgt mimix curation exos4_human Exosome complex component RRP41 EXOSC4 RRP41 SKI6 Ribosomal RNA-processing protein 41 Exosome component 4 p12A protein protein human Homo sapiens Human MAGLELLSDQGYRVDGRRAGELRKIQARMGVFAQADGSAYIEQGNTKALAVVYGPHEIRGSRARALPDRALVNCQYSSATFSTGERKRRPHGDRKSCEMGLQLRQTFEAAILTQLHPRSQIDIYVQVLQADGGTYAACVNAATLAVLDAGIPMRDFVCACSAGFVDGTALADLSHVEEAAGGPQLALALLPASGQIALLEMDARLHEDHLERVLEAAAQAARDVHTLLDRVVRQHVREASILLGD DIP protein Q9NPD3 original sequence version: 133 7A24E97897DAF313 exos2_human Exosome complex component RRP4 EXOSC2 RRP4 Ribosomal RNA-processing protein 4 Exosome component 2 protein protein human Homo sapiens Human MAMEMRLPVARKPLSERLGRDTKKHLVVPGDTITTDTGFMRGHGTYMGEEKLIASVAGSVERVNKLICVKALKTRYIGEVGDIVVGRITEVQQKRWKVETNSRLDSVLLLSSMNLPGGELRRRSAEDELAMRGFLQEGDLISAEVQAVFSDGAVSLHTRSLKYGKLGQGVLVQVSPSLVKRQKTHFHDLPCGASVILGNNGFIWIYPTPEHKEEEAGGFIANLEPVSLADREVISRLRNCIISLVTQRMMLYDTSILYCYEASLPHQIKDILKPEIMEEIVMETRQRLLEQEG DIP protein Q13868 original sequence version: 143 882033F50791643F exos3_human Exosome complex component RRP40 EXOSC3 RRP40 CGI-102 Ribosomal RNA-processing protein 40 Exosome component 3 p10 protein protein human Homo sapiens Human MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES DIP protein Q9NQT5 original sequence version: 130 DIP protein Q9NQT5 original sequence version: 72 DIP protein Q9NQT5 original sequence version: 117 DIP protein Q9NQT5 original sequence version: 136 264322144A199166 exos9_human Exosome complex component RRP45 EXOSC9 PMSCL1 Exosome component 9 Polymyositis/scleroderma autoantigen 1 Autoantigen PM/Scl 1 Polymyositis/scleroderma autoantigen 75 kDa P75 polymyositis-scleroderma overlap syndrome-associated autoantigen protein protein human Homo sapiens Human MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNRATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLNHDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPNEREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGGKFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQDAPIILSDSEEEEMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN DIP protein Q06265 original sequence version: 138 7E27322F094ED3F3 exos8_human Exosome complex component RRP43 OIP2 RRP43 EXOSC8 Ribosomal RNA-processing protein 43 Exosome component 8 p9 Opa-interacting protein 2 protein protein human Homo sapiens Human MAAGFKTVEPLEYYRRFLKENCRPDGRELGEFRTTTVNIGSISTADGSALVKLGNTTVICGVKAEFAAPSTDAPDKGYVVPNVDLPPLCSSRFRSGPPGEEAQVASQFIADVIENSQIIQKEDLCISPGKLVWVLYCDLICLDYDGNILDACTFALLAALKNVQLPEVTINEETALAEVNLKKKSYLNIRTHPVATSFAVFDDTLLIVDPTGEEEHLATGTLTIVMDEEGKLCCLHKPGGSGLTGAKLQDCMSRAVTRHKEVKKLMDEVIKSMKPK DIP protein Q96B26 original sequence version: 125 FC8F5BAE74A1FF55 exosx_human Exosome component 10 PMSCL2 EXOSC10 PMSCL Polymyositis/scleroderma autoantigen 2 Autoantigen PM/Scl 2 Polymyositis/scleroderma autoantigen 100 kDa P100 polymyositis-scleroderma overlap syndrome-associated autoantigen RRP6 protein protein human Homo sapiens Human MAPPSTREPRVLSATSATKSDGEMVLPGFPDADSFVKFALGSVVAVTKASGGLPQFGDEYDFYRSFPGFQAFCETQGDRLLQCMSRVMQYHGCRSNIKDRSKVTELEDKFDLLVDANDVILERVGILLDEASGVNKNQQPVLPAGLQVPKTVVSSWNRKAAEYGKKAKSETFRLLHAKNIIRPQLKFREKIDNSNTPFLPKIFIKPNAQKPLPQALSKERRERPQDRPEDLDVPPALADFIHQQRTQQVEQDMFAHPYQYELNHFTPADAVLQKPQPQLYRPIEETPCHFISSLDELVELNEKLLNCQEFAVDLEHHSYRSFLGLTCLMQISTRTEDFIIDTLELRSDMYILNESLTDPAIVKVFHGADSDIEWLQKDFGLYVVNMFDTHQAARLLNLGRHSLDHLLKLYCNVDSNKQYQLADWRIRPLPEEMLSYARDDTHYLLYIYDKMRLEMWERGNGQPVQLQVVWQRSRDICLKKFIKPIFTDESYLELYRKQKKHLNTQQLTAFQLLFAWRDKTARREDESYGYVLPNHMMLKIAEELPKEPQGIIACCNPVPPLVRQQINEMHLLIQQAREMPLLKSEVAAGVKKSGPLPSAERLENVLFGPHDCSHAPPDGYPIIPTSGSVPVQKQASLFPDEKEDNLLGTTCLIATAVITLFNEPSAEDSKKGPLTVAQKKAQNIMESFENPFRMFLPSLGHRAPVSQAAKFDPSTKIYEISNRWKLAQVQVQKDSKEAVKKKAAEQTAAREQAKEACKAAAEQAISVRQQVVLENAAKKRERATSDPRTTEQKQEKKRLKISKKPKDPEPPEKEFTPYDYSQSDFKAFAGNSKSKVSSQFDPNKQTPSGKKCIAAKKIKQSVGNKSMSFPTGKSDRGFRYNWPQR DIP protein Q01780 original sequence version: 154 A37BDC8F49BF2E57 exosc10-exosc2 1 3 unspecified role unspecified role neutral component neutral component 6 unspecified role unspecified role neutral component neutral component 5 unspecified role unspecified role neutral component neutral component 2 unspecified role unspecified role neutral component neutral component 7 unspecified role unspecified role neutral component neutral component 4 unspecified role unspecified role neutral component neutral component association association 2