UniProt UniProt http://www.uniprot.org Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. (0021-9258) 2007 mimix curation Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu 26-Sep-2011: Contacted by JYOTI. orchard human-mda_mb_468 Homo sapiens MDA-MB-468 mda_mb_468 MDA-MB-468 breast adenocarcinoma Species: human, Black; Tissue: breast; Tumor: adenocarcinoma; Derived from: pleural effusion confocal microscopy confocal microscopy immunostaining immunostaining Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu Accepted 2011-JUL-20 by ORCHARD 26-Sep-2011: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2007 orchard mimix curation Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. (0021-9258) 2007 mimix curation Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu 26-Sep-2011: Contacted by JYOTI. orchard in vitro In vitro pull down pull down weight by comassie molecular weight estimation by coomasie staining weight by comassie Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu Accepted 2011-JUL-20 by ORCHARD 26-Sep-2011: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2007 orchard mimix curation Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. (0021-9258) 2007 mimix curation Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu 26-Sep-2011: Contacted by JYOTI. orchard human Homo sapiens Human anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu Accepted 2011-JUL-20 by ORCHARD 26-Sep-2011: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2007 orchard mimix curation Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2. J. Biol. Chem. (0021-9258) 2007 mimix curation Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu 26-Sep-2011: Contacted by JYOTI. orchard human-mda_mb_468 Homo sapiens MDA-MB-468 mda_mb_468 MDA-MB-468 breast adenocarcinoma Species: human, Black; Tissue: breast; Tumor: adenocarcinoma; Derived from: pleural effusion anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Zoudilova M., Kumar P., Ge L., Wang P., Bokoch G.M., DeFea K.A. fig 10 a colocalization not included. unspecific antibody kathryn.defea@ucr.edu Accepted 2011-JUL-20 by ORCHARD 26-Sep-2011: Contacted by JYOTI. J. Biol. Chem. (0021-9258) 2007 orchard mimix curation arrb1_human Beta-arrestin-1 Arrestin beta-1 ARRB1 ARR1 Non-visual arrestin-2 protein protein human Homo sapiens Human MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR DIP protein P49407 original sequence version: 138 DIP protein P49407 original sequence version: 69 DIP protein P49407 original sequence version: 92 DIP protein P49407 original sequence version: 103 0A3C135092338D10 limk1_human LIM domain kinase 1 LIMK1 LIMK protein protein human Homo sapiens Human MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDTLGHGLGPETSPLSSPAYTPSGEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVCRPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRRGESGLPAHPEVPD DIP protein P53667 original sequence version: 113 9838BEFBE7006447 cof1_human Cofilin-1 CFL1 CFL Cofilin, non-muscle isoform 18 kDa phosphoprotein protein protein human Homo sapiens Human MASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL DIP protein P23528 original sequence version: 124 DIP protein P23528 original sequence version: 172 589EF8FC1EC13719 arrb2_rat Beta-arrestin-2 Arrb2 Arrestin beta-2 protein protein rat Rattus norvegicus (Rat) Rat MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPMPNPPRPPTRLQDRLLKKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLIIRKVQFAPETPGPQPSAETTRHFLMSDRRSLHLEASLDKELYYHGEPLNVNVHVTNNSAKTVKKIRVSVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGQLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHITLPRPQSAPREIDIPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDCDDQFC DIP protein P29067 original sequence version: 115 DIP protein P29067 original sequence version: 112 DIP protein P29067 original sequence version: 100 0DFA6A897C2B86BA arrb2_human Beta-arrestin-2 Arrestin beta-2 ARRB2 ARB2 ARR2 Non-visual arrestin-3 protein protein human Homo sapiens Human MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC DIP protein P32121 original sequence version: 148 DIP protein P32121 original sequence version: 102 DIP protein P32121-1 original sequence version: 86 DIP protein P32121-1 original sequence version: 100 DIP protein P32121 original sequence version: 153 DEEC507D4A7B84FF plpp_human Chronophin CIN PDXP PLP PLPP Pyridoxal phosphate phosphatase protein protein human Homo sapiens Human MARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED 33466C35A76B458C arrb1_rat Beta-arrestin-1 Arrb1 Arrestin beta-1 protein protein rat Rattus norvegicus (Rat) Rat MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEPPHREVPESETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKDEEDDGTGSPHLNNR DIP protein P29066 original sequence version: 70 DIP protein P29066 original sequence version: 90 DIP protein P29066 original sequence version: 79 0A3C07D71B7ABC55 cfl1-arrb1 4 7 unspecified role unspecified role bait bait 5 unspecified role unspecified role prey prey 9 unspecified role unspecified role prey prey association association specifity of cofolin: nin-muscle cells used and antibody supplier states that the antibody 'may not recognize cofilin-2 muscle form. 4a cfl1-arrb2 3 8 unspecified role unspecified role prey prey 7 unspecified role unspecified role bait bait physical association physical association 4b species origin for beta-arestin: from Lefkowitz lab which worked with rat beta-arrestin, and mentioned for fig 8. CIN looked up in ref 36. arrb1-cfl1 1 5 unspecified role unspecified role neutral component neutral component 7 unspecified role unspecified role neutral component neutral component colocalization colocalization 5c arrb1-arrb2 1 7 unspecified role unspecified role neutral component neutral component 9 unspecified role unspecified role neutral component neutral component colocalization colocalization 5c arrb1-pdxp 3 10 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait physical association physical association 8b checked species: Myc-tagged CIN constructs have been described previously (36) pdxp-arrb1 3 11 unspecified role unspecified role prey prey 10 unspecified role unspecified role bait bait physical association physical association 8b checked species: Myc-tagged CIN constructs have been described previously (36) limk1-arrb1 2 6 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey mouse-nih_3t3 Mus musculus Swiss NIH 3t3 embryo fibroblast cells nih_3t3 Mouse Swiss NIH embryo contact inhibited fibroblast cells physical association physical association 10b limk1-arrb2 2 6 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey mouse-nih_3t3 Mus musculus Swiss NIH 3t3 embryo fibroblast cells nih_3t3 Mouse Swiss NIH embryo contact inhibited fibroblast cells physical association physical association 10b arrb1-limk1-2 3 11 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey physical association physical association 10c arrb2-link1 3 8 unspecified role unspecified role bait bait 6 unspecified role unspecified role prey prey physical association physical association 10c