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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
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      </bibref>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="20875083" refType="primary-reference" refTypeAc="MI:0358"/>
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            <secondaryRef db="imex" dbAc="MI:0670" id="IM-15629" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line.</attribute>
            <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
            <attribute name="publication year" nameAc="MI:0886">2010</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Sato A., Naito T., Hiramoto A., Goda K., Omi T., Kitade Y., Sasaki T., Matsuda A., Fukushima M., Wataya Y., Kim HS.</attribute>
            <attribute name="imex-exported"/>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
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        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="9606">
            <names>
              <shortLabel>human-ht1080</shortLabel>
              <fullName>Homo sapiens HT1080 fribrosarcoma cell line</fullName>
            </names>
            <cellType>
              <names>
                <shortLabel>ht1080</shortLabel>
                <fullName>confirmed as human with IEF of AST, LDH, NP established from the biopsy from a fibrosarcoma of a 35-year-old Caucasian man in 1972</fullName>
              </names>
              <xref>
                <primaryRef db="cabri" dbAc="MI:0246" id="ACC 315" refType="identity" refTypeAc="MI:0356"/>
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              </xref>
            </cellType>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>anti bait coip</shortLabel>
            <fullName>anti bait coimmunoprecipitation</fullName>
            <alias type="synonym" typeAc="MI:1041">anti bait coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0006" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>predetermined</shortLabel>
            <fullName>predetermined participant</fullName>
            <alias type="synonym" typeAc="MI:1041">predetermined</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Sato A., Naito T., Hiramoto A., Goda K., Omi T., Kitade Y., Sasaki T., Matsuda A., Fukushima M., Wataya Y., Kim HS.</attribute>
          <attribute name="journal" nameAc="MI:0885">FEBS J. (1742-464X)</attribute>
          <attribute name="publication year" nameAc="MI:0886">2010</attribute>
          <attribute name="imex-exported"/>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>iqga1_human</shortLabel>
          <fullName>Ras GTPase-activating-like protein IQGAP1</fullName>
          <alias type="gene name" typeAc="MI:0301">IQGAP1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">KIAA0051</alias>
          <alias type="gene name synonym" typeAc="MI:0302">p195</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P46940" version="SP_76" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000268182" version="SP_220" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="A7MBM3" version="SP_104" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-297509" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000140575" version="SP_220" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005516" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005547" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005737" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005874" version="SP_220"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0070062" version="SP_220"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990138" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990776" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000048" version="SP_220"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030667" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000593" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001202" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001715" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001936" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR008936" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR023152" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_220"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036872" version="SP_220"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P46940" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1X0H" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2RR8" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FAY" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3I6X" version="SP_220"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5L0O" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-373753" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-381676" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5626467" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-5674135" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6798695" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802946" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802948" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802952" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6802955" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8980692" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013106" version="SP_220"/>
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          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9013424" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9649948" version="SP_220"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-9656223" version="SP_220"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_003861.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-32597N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MSAADEVDGLGVARPHYGSVLDNERLTAEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFKLGLAPQIQDLYGKVDFTEEEINNMKTELEKYGIQMPAFSKIGGILANELSVDEAALHAAVIAINEAIDRRIPADTFAALKNPNAMLVNLEEPLASTYQDILYQAKQDKMTNAKNRTENSERERDVYEELLTQAEIQGNINKVNTFSALANIDLALEQGDALALFRALQSPALGLRGLQQQNSDWYLKQLLSDKQQKRQSGQTDPLQKEELQSGVDAANSAAQQYQRRLAAVALINAAIQKGVAEKTVLELMNPEAQLPQVYPFAADLYQKELATLQRQSPEHNLTHPELSVAVEMLSSVALINRALESGDVNTVWKQLSSSVTGLTNIEEENCQRYLDELMKLKAQAHAENNEFITWNDIQACVDHVNLVVQEEHERILAIGLINEALDEGDAQKTLQALQIPAAKLEGVLAEVAQHYQDTLIRAKREKAQEIQDESAVLWLDEIQGGIWQSNKDTQEAQKFALGIFAINEAVESGDVGKTLSALRSPDVGLYGVIPECGETYHSDLAEAKKKKLAVGDNNSKWVKHWVKGGYYYYHNLETQEGGWDEPPNFVQNSMQLSREEIQSSISGVTAAYNREQLWLANEGLITRLQARCRGYLVRQEFRSRMNFLKKQIPAITCIQSQWRGYKQKKAYQDRLAYLRSHKDEVVKIQSLARMHQARKRYRDRLQYFRDHINDIIKIQAFIRANKARDDYKTLINAEDPPMVVVRKFVHLLDQSDQDFQEELDLMKMREEVITLIRSNQQLENDLNLMDIKIGLLVKNKITLQDVVSHSKKLTKKNKEQLSDMMMINKQKGGLKALSKEKREKLEAYQHLFYLLQTNPTYLAKLIFQMPQNKSTKFMDSVIFTLYNYASNQREEYLLLRLFKTALQEEIKSKVDQIQEIVTGNPTVIKMVVSFNRGARGQNALRQILAPVVKEIMDDKSLNIKTDPVDIYKSWVNQMESQTGEASKLPYDVTPEQALAHEEVKTRLDSSIRNMRAVTDKFLSAIVSSVDKIPYGMRFIAKVLKDSLHEKFPDAGEDELLKIIGNLLYYRYMNPAIVAPDAFDIIDLSAGGQLTTDQRRNLGSIAKMLQHAASNKMFLGDNAHLSIINEYLSQSYQKFRRFFQTACDVPELQDKFNVDEYSDLVTLTKPVIYISIGEIINTHTLLLDHQDAIAPEHNDPIHELLDDLGEVPTIESLIGESSGNLNDPNKEALAKTEVSLTLTNKFDVPGDENAEMDARTILLNTKRLIVDVIRFQPGETLTEILETPATSEQEAEHQRAMQRRAIRDAKTPDKMKKSKSVKEDSNLTLQEKKEKIQTGLKKLTELGTVDPKNKYQELINDIARDIRNQRRYRQRRKAELVKLQQTYAALNSKATFYGEQVDYYKSYIKTCLDNLASKGKVSKKPREMKGKKSKKISLKYTAARLHEKGVLLEIEDLQVNQFKNVIFEISPTEEVGDFEVKAKFMGVQMETFMLHYQDLLQLQYEGVAVMKLFDRAKVNVNLLIFLLNKKFYGK</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein P46940 original sequence version: 158</attribute>
          <attribute name="remark-internal">DIP protein P46940 original sequence version: 152</attribute>
          <attribute name="crc64">A52EC629596EAC33</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>kif23_human</shortLabel>
          <fullName>Kinesin-like protein KIF23</fullName>
          <alias type="gene name" typeAc="MI:0301">KIF23</alias>
          <alias type="gene name synonym" typeAc="MI:0302">KNSL5</alias>
          <alias type="gene name synonym" typeAc="MI:0302">MKLP1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Mitotic kinesin-like protein 1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Kinesin-like protein 5</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q02241" version="SP_82" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q8WVP0" version="SP_82" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000260363" version="SP_211" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000497065" version="SP_211" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-2558308" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B4E1K0" version="SP_151" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-306852" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_004847.2"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_612565.1"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000137807" version="SP_211" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000260363" version="SP_211" refType="transcript"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000647715" version="SP_211" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000022" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003777" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005654" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005813" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005819" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005871" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005874" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005925" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007018" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0008017" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0030496" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0032467" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051256" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0072686" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0090543" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0097149" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:1990939" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR001752" version="SP_211"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000281" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR019821" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027417" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR027640" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038105" version="SP_211"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q02241" version="SP_211"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3VHX" version="SP_211"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-2132295" version="SP_211"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-6811434" version="SP_211"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-68884" version="SP_211"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR032384" version="SP_211"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-983189" version="SP_211"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000260363"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000352331"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000304978"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000497065"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-40359N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MKSARAKTPRKPTVKKGSQTNLKDPVGVYCRVRPLGFPDQECCIEVINNTTVQLHTPEGYRLNRNGDYKETQYSFKQVFGTHTTQKELFDVVANPLVNDLIHGKNGLLFTYGVTGSGKTHTMTGSPGEGGLLPRCLDMIFNSIGSFQAKRYVFKSNDRNSMDIQCEVDALLERQKREAMPNPKTSSSKRQVDPEFADMITVQEFCKAEEVDEDSVYGVFVSYIEIYNNYIYDLLEEVPFDPIKPKPPQSKLLREDKNHNMYVAGCTEVEVKSTEEAFEVFWRGQKKRRIANTHLNRESSRSHSVFNIKLVQAPLDADGDNVLQEKEQITISQLSLVDLAGSERTNRTRAEGNRLREAGNINQSLMTLRTCMDVLRENQMYGTNKMVPYRDSKLTHLFKNYFDGEGKVRMIVCVNPKAEDYEENLQVMRFAEVTQEVEVARPVDKAICGLTPGRRYRNQPRGPVGNEPLVTDVVLQSFPPLPSCEILDINDEQTLPRLIEALEKRHNLRQMMIDEFNKQSNAFKALLQEFDNAVLSKENHMQGKLNEKEKMISGQKLEIERLEKKNKTLEYKIEILEKTTTIYEEDKRNLQQELETQNQKLQRQFSDKRRLEARLQGMVTETTMKWEKECERRVAAKQLEMQNKLWVKDEKLKQLKAIVTEPKTEKPERPSRERDREKVTQRSVSPSPVPLSSNYIAQISNGQQLMSQPQLHRRSNSCSSISVASCISEWEQKIPTYNTPLKVTSIARRRQQEPGQSKTCIVSDRRRGMYWTEGREVVPTFRNEIEIEEDHCGRLLFQPDQNAPPIRLRHRRSRSAGDRWVDHKPASNMQTETVMQPHVPHAITVSVANEKALAKCEKYMLTHQELASDGEIETKLIKGDIYKTRGGGQSVQFTDIETLKQESPNGSRKRRSSTVAPAQPDGAESEWTDVETRCSVAVEMRAGSQLGPGYQHHAQPKRKKP</sequence>
        <attributeList>
          <attribute name="remark-internal">DIP protein Q02241 original sequence version: 104</attribute>
          <attribute name="remark-internal">DIP protein Q02241 original sequence version: 159</attribute>
          <attribute name="remark-internal">DIP protein Q02241 original sequence version: 160</attribute>
          <attribute name="crc64">B2AA784D2D236A90</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>rn5a_human</shortLabel>
          <fullName>2-5A-dependent ribonuclease</fullName>
          <alias type="gene name" typeAc="MI:0301">RNASEL</alias>
          <alias type="gene name synonym" typeAc="MI:0302">RNS4</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ribonuclease L</alias>
          <alias type="gene name synonym" typeAc="MI:0302">Ribonuclease 4</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="Q05823" version="SP_101" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q6AI46" version="SP_144" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q5W0L2" version="SP_131" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="MINT-7990548" refType="intact-secondary"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSP00000356530" version="SP_199" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8390477" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_066956.1"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-61367N"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENSG00000135828" version="SP_199" refType="gene"/>
          <secondaryRef db="ensembl" dbAc="MI:0476" id="ENST00000367559" version="SP_199" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003723" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004521" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004540" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004672" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005759" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005829" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006364" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006396" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006397" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006468" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016363" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019843" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042802" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043021" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043488" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045071" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045444" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0045944" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046326" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_199"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051607" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR000719" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002110" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR010513" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR011009" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR020683" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036770" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038357" version="SP_199"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR042745" version="SP_199"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="Q05823" version="SP_199"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1WDY" version="SP_199"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4G8K" version="SP_199"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4G8L" version="SP_199"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4OAU" version="SP_199"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4OAV" version="SP_199"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-8983711" version="SP_199"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-HSA-909733" version="SP_199"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="9606">
          <names>
            <shortLabel>human</shortLabel>
            <fullName>Homo sapiens</fullName>
            <alias type="synonym" typeAc="MI:1041">Human</alias>
          </names>
        </organism>
        <sequence>MESRDHNNPQEGPTSSSGRRAAVEDNHLLIKAVQNEDVDLVQQLLEGGANVNFQEEEGGWTPLHNAVQMSREDIVELLLRHGADPVLRKKNGATPFILAAIAGSVKLLKLFLSKGADVNECDFYGFTAFMEAAVYGKVKALKFLYKRGANVNLRRKTKEDQERLRKGGATALMDAAEKGHVEVLKILLDEMGADVNACDNMGRNALIHALLSSDDSDVEAITHLLLDHGADVNVRGERGKTPLILAVEKKHLGLVQRLLEQEHIEINDTDSDGKTALLLAVELKLKKIAELLCKRGASTDCGDLVMTARRNYDHSLVKVLLSHGAKEDFHPPAEDWKPQSSHWGAALKDLHRIYRPMIGKLKFFIDEKYKIADTSEGGIYLGFYEKQEVAVKTFCEGSPRAQREVSCLQSSRENSHLVTFYGSESHRGHLFVCVTLCEQTLEACLDVHRGEDVENEEDEFARNVLSSIFKAVQELHLSCGYTHQDLQPQNILIDSKKAAHLADFDKSIKWAGDPQEVKRDLEDLGRLVLYVVKKGSISFEDLKAQSNEEVVQLSPDEETKDLIHRLFHPGEHVRDCLSDLLGHPFFWTWESRYRTLRNVGNESDIKTRKSESEILRLLQPGPSEHSKSFDKWTTKINECVMKKMNKFYEKRGNFYQNTVGDLLKFIRNLGEHIDEEKHKKMKLKIGDPSLYFQKTFPDLVIYVYTKLQNTEYRKHFPQTHSPNKPQCDGAGGASGLASPGC</sequence>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
          <attribute name="crc64">91385EA307E3CE1D</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="5" imexId="IM-15629-1">
        <names>
          <shortLabel>rnasel-iqgap1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990574" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8390471" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-15629-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="6">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">RNaseL</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990576" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>ms participant</shortLabel>
                  <fullName>Identification by mass spectrometry</fullName>
                  <alias type="synonym" typeAc="MI:1041">ms participant</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0427" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608794" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="7">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">Ras GTPase-activating-like protein IQGAP1</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990580" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>ms participant</shortLabel>
                  <fullName>Identification by mass spectrometry</fullName>
                  <alias type="synonym" typeAc="MI:1041">ms participant</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0427" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608794" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="8">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">Kinesin-like protein KIF23</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990582" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>ms participant</shortLabel>
                  <fullName>Identification by mass spectrometry</fullName>
                  <alias type="synonym" typeAc="MI:1041">ms participant</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0427" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608794" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>association</shortLabel>
            <fullName>association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
          <attribute name="figure legend" nameAc="MI:0599">fs1; f1; t1</attribute>
        </attributeList>
      </interaction>
      <interaction id="9" imexId="IM-15629-2">
        <names>
          <shortLabel>rnasel-iqgap1-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990598" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8390522" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-15629-2" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="10">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">RNaseL</alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990600" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>4</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>bait</shortLabel>
                  <fullName>bait</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0496" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-49" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
          <participant id="11">
            <names>
              <alias type="author assigned name" typeAc="MI:0345">IQGAP1 </alias>
            </names>
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-7990601" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>western blot</shortLabel>
                  <fullName>western blot</fullName>
                  <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
                  <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>prey</shortLabel>
                  <fullName>prey</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0498" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-58" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>living cell</shortLabel>
                  <fullName>living cell</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0349" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537765" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
              <experimentalPreparation>
                <names>
                  <shortLabel>physiological level</shortLabel>
                  <fullName>physiological level</fullName>
                  <alias type="go synonym" typeAc="MI:0303">endogenous level</alias>
                  <alias type="go synonym" typeAc="MI:0303">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous</alias>
                  <alias type="synonym" typeAc="MI:1041">endogenous level</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0222" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537793" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>physical association</shortLabel>
            <fullName>physical association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0915" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813147" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">homomint</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
          <attribute name="figure legend" nameAc="MI:0599">f2b; f3b; f4a</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>