IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. J. Virol. (0022-538X) 2008 imex curation Rozen R., Sathish N., Li Y., Yuan Y., Rozen R., Sathish N., Li Y., Yuan Y. yuan2@pobox.upenn.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip anti tag western anti tag western blot anti tag western Rozen R., Sathish N., Li Y., Yuan Y. The ORF11, ORF21, ORF27, ORF33, ORF45, ORF52, ORF63, ORF75,AND ORF64 used in the experiment have V5 or Myc or FLAG tag and one of these has been used to perform the CoIP and the other to carry out the anti-tag western hence exact tag could not be added as feature on the interactors. yuan2@pobox.upenn.edu Accepted 2010-APR-22 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. J. Virol. (0022-538X) 2008 orchard IMEx Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. J. Virol. (0022-538X) 2008 imex curation Rozen R., Sathish N., Li Y., Yuan Y., Rozen R., Sathish N., Li Y., Yuan Y. yuan2@pobox.upenn.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Rozen R., Sathish N., Li Y., Yuan Y. yuan2@pobox.upenn.edu Accepted 2010-APR-22 by ORCHARD. J. Virol. (0022-538X) 2008 orchard IMEx Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. J. Virol. (0022-538X) 2008 imex curation Rozen R., Sathish N., Li Y., Yuan Y., Rozen R., Sathish N., Li Y., Yuan Y. yuan2@pobox.upenn.edu 25-Jun-2010: Contacted by JYOTI. orchard Only protein-protein interactions human-293 Homo sapiens transformed primary embryonal kidney cells Human 293 Transformed human primary embryonal kidney cells. The Cell type named 293 is synonymous with HEK-293. anti tag coip anti tag coimmunoprecipitation anti tag coip western blot western blot Immuno blot Immuno blot Rozen R., Sathish N., Li Y., Yuan Y. yuan2@pobox.upenn.edu Accepted 2010-APR-22 by ORCHARD. 25-Jun-2010: Contacted by JYOTI. J. Virol. (0022-538X) 2008 orchard IMEx o40925_hhv8 Major capsid protein MCP protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MEATLEQRPFPYLATEANLLTQIKESAADGLFKSFQLLLGKDAREGSVRFEALLGVYTNVVEFVKFLETALAAACVNTEFKDLRRMIDGKIQFKISMPTIAHGDGRRPNKQRQYIVMKACNKHHIGAEIELAAADIELLFAEKETPLDFTEYAGAIKTITSALQFGMDALERGLVDTVLAVKLRHAPPVFILKTLGDPVYSERGLKKAVKSDMVSMFKAHLIEHSFFLDKAELMTRGKQYVLTMLSDMLAAVCEDTVFKGVSTYTTASGQQVAGVLETTDSVMRRLMNLLGQVESAMSGPAAYASYVVRGANLVTAVSYGRAMRNFEQFMARIVDHPNALPSVEGDKAALADGHDEIQRTRIAASLVKIGDKFVAIESLQRMYNETQFPCPLNRRIQYTYFFPVGLHLPVPRYSTSVSVRGVESPAIQSTETWVVNKNNVPLCFGYQNALKSICHPRMHNPTQSAQALNQAFPDPDGGHGYGLRYEQTPNMNLFRTFHQYYMGKNVAFVPDVAQKALVTTEDLLHPTSHRLLRLEVHPFFDFFVHPCPGARGSYRATHRTMVGNIPQPLAPREFQESRGAQFDDVTNMTHVIDQLTIDVIQETAFDPAYPLFCYVIEAMIHGQEEKFVMNMPLIALVIQTYWVNSGKLAFVNSYHMVRFICTHMGNGSIPKEAHGHYRKILGELIALEQALLKLAGHETVGRTPITHLVSALLDPHLLPPFAYHDVFTDLMQKSSRQPIIKIGDQNYDNPQNRATFINLRGRMEDLVNNLVNIYQTRVNEDHDERHVLDVAPLDENDYNPVLEKLFYYVLMPVCSNGHMCGMGVDYQNVALTLTYNGPVFADVVNAQDDILLHLENGTLKDILQAGDIRPTVDMIRVLCTSFLTCPFVTQAARVITKRDPAQSFATHEYGKDVAQTVLVNGFGAFAVADRSREAAETMFYPVPFNKLYADPLVAATLHPLLANYVTRLPNQRNAVVFNVPSNLMAEYEEWHKSPVAAYAASCQATPGAISAMVSMHQKLSAPSFICQAKHRMHPGFAMTVVRTDEVLAEHILYCSRASTSMFVGLPSVVRREVRSDAVTFEITHEIASLHTALGYSSVIAPAHVAAITTDMGVHCQDLFMIFPGDAYQDRQLHDYIKMKAGVQTGSPGNRMDHVGYTAGVPRCENLPGLSHGQLATCEIIPTPVTSDVAYFQTPSNPRGRAACVVSCDAYSNESAERLLYDHSIPDPAYECRSTNNPWASQRGSLGDVLYNITFRQTALPGMYSPCRQFFHKEDIMRYNRGLYTLVNEYSARLAGAPATSTTDLQYVVVNGTDVFLDQPCHMLQEAYPTLAASHRVMLDEYMSNKQTHAPVHMGQYLIEEVAPMKRLLKLGNKVVY F10B59E380745A49 orf75_hhv8p Protein ORF75 ORF75 protein protein hhv8p Human herpesvirus 8 Kaposi's sarcoma-associated herpesvirus HHV-8 MAYDVTGLWLESDLTADEEAFVSFYTSRTGTLTLVPGGTGGYYLLWITFRRPPTSREERERRDVEIQTVLAVLSPLLGYPHVIRRSPPRGSERVVSFGYGPNINHRPTTLSTELGVLLRELGLQEWARVEVGRHLVSKITQTLLEPHPPQFIRAFTQNTDLVPYEGLEVPEGPQPVARPHIEDDVIMQAVMISLGADLLPLAVQASTGDNYNVARYFVIPGRCTMERWPWNCARQAFGIHGAYTHVHSSVQRGIRGLGNLLFHSTLFPGGQTQGALTGLYATEPALGPRAHSRFRRIFAKGVQQAEMLQGAGVPTLGGFLKTVRTIATTPGNALAVCSISTTTSKECISLRRMIPQQTVVCLGRFEPTDGPDTYPNLYRDSSDNAVRILETLKLVQRLAKGPIFSGLNRSHDPAPVVRHLQALAPRTGLELFVSKLPDEVRAHLPADPAAGPDAVEAAVAEHFLNVYCSLVFAVVAESGAVPGDLGETPLEVLQRAARLCACQITVLGRTSEQPGIRIVDDLTGETTRVFSVDQPSSTPPSPWLALSDGVRVSGHPEDVDWGLFATGSTIHQLLRHATVGSKEFFTRHMDRCSNGLIAQQAGVGPLDIPVSDYHLVLHSSMLAERVAPRVPDTVEAITPSMANLLHKDFETWVKALPQELLPVPAWRGQAMAMGEQAYKMATNVSTGATYAITEALTNLMFSPVSKLQDVVLTGAVAWSPEDHQAGLLQECLFACKEFCRELGVALSISSAASSPTLSERHVRITQQQETVEVLPFNSVVFTSWAEVKGSRYRVTPDVKVEGNALVYLAVNQSCLIAGSTFEHNFLASRHPIPPLNPSTVASLFMLVKYLMSKRLIVSGHDIGDGGLLPSAIEMALAGCRGLQLSLPAHPNPLELMVSETPGALVEVPQVHLSEVLRAARDYRCVAHPLGTVGPEGQGNNVTILQNETVVFQETLTSLQVSWTSFSDEMWNLVTPPLHPLEDMHRKDLGRLEHHLGSLRAMCLGSQLRLFSCPTSPRRVAALVLPGSSAPYALMAALQNTGFEVATVTVEELKRGQSLSGFSGLITCLRTGCQASYASARGWVLALCNDPTCASTLTEFLNRPDTFSICCGEVGFQLLVALGVVGRSESSPYTYGPTPPQRWAVNLETNVSKLYDSHWLNIQIPQNTKSVFLRVLRGTVLPSWAQGEYLGVRYEQDALEYILRQRGEITLTYHGNAADETLPARHYPRNPTGNSTVAGLTSSDGRHAALIIDPSLMFHPWQWQHVPPDLTPLSMSPWAMAFQSIYLWSVKKINDHH 72FCB9CC407E9AEB q80pp8_hhv8 ORF26 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 NGFDIVFPMVVPQQLGHAILQQLLVYHIYSKISAGAPGDVNMAELDLYTTNVSFM A89F54D7DF086F80 d0uzp5_hhv8 Cytoplasmic envelopment protein 2 ORF33 HHV8GK18_gp37 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MASRRRKLRNFLNKECIWTVNPMSGDHIKVFNACTSISPVYDPELVTSYALSVPAYNVSVAILLHKVMGPCVAVGINGEMIMYVVSQCVSVRPVPGRDGMALIYFGRFLEEASGLRFPYIAPPPSREHVPDLTRQELVHTSQVVRRGDLTNCTMGLEFRNVNPFVWLGGGSVWLLFLGVDYMAFCPGVDGMPSLARVAALLTRCDHPDCVHCHGLRGHVNVFRGYCSAQSPGLSNICPCIKSCGTGNGVTRVTGNRNFLGLLFDPIVQSRVTALKITSHPTPTHVENVLTGVLDDGTLVPSSKAPWVLLRMSDYFSRLLIYECKKLKALGLRSY 160ACB98594EFA4F o40931_hhv8 Envelope glycoprotein M ORF39 gM HHV8GK18_gp43 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MRASKSDRFLMSSWVKLLFVAVIMYICSAVVPMAATYEGLGFPCYFNNLVNYSALNLTVRNSAKHLTPTLFLEKPEMLVYIFWTFIVDGIAIVYYCLAAVAVYRAKHVHATTMMSMQSWIALLGSHSVLYVAILRMWSMQLFIHVLSYKHVLMAAFVYCIHFCISFAHIQSLITCNSAQWEIPLLEQHVPDNTMMESLLTRWKPVCVNLYLSTTALEMLLFSLSTMMAVGNSFYVLVSDAIFGAVNMFLALTVVWYINTEFFLVKFMRRQVGFYVGVFVGYLILLLPVIRYENAFVQANLHYIVAINISCIPILCILAIVIRVIRSDWGLCTPSAAYMPLATSAPTVDRTPTVHQKPPPLPAKTRARAKVKDISTPAPRTQYQSDHESDSEIDETQMIFI F7D162F0199EE670 q76rf5_hhv8 Inner tegument protein ORF63 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MDGTDALEKLTKGLSGGGGSLHQTKLLMEFQLRGLPVPALLNSSTTEQFLNTVAQLPTDLSKFIRDYRVFALVRAAYFLEPPSSIDPLEAARALGRLVDILSSQPPQNTAPAQPPTSDDTLNNCTLLKLLAHYADQIAGFKTPALPPVPPGIIGLFTCVEQMYHACFQKYWAAALPPMWILTYDPPTSPLQDWLIVAYGNKEGLLLPSGIPSEEVLAKTLVTEHHELFVSRSNSTETAVTMPVSKERALAIYRVFAKGEVVAENTPILAFTDVELSTLKPHYLFIYDFIIEALCKSYTYSCTQARLESFLSRGIDFMTDLGQYLDTATSGKQQLTHSQIKEIKYRLLSCGLSASACDVFRTVIMTLPYRPTPNLANLSTFMGMVHQLTMFGHYFYRCLGSYSPTGLAFTELQKILTRASAEQTERNPWRHPGISDIPLRWKISRALAFFVPPAPINTLQRVYAALPSQLMRAIFEISVKTTWGGAVPANLARDIDTGPNTQHISSTPPPTLKDVETYCQGLRVGDTEYDEDIVRSPLFADAFTKSHLLPILREVLENRLQKNRALFQIRWLIIFAAEAATGLIPARRPLARAYFHIMDILEERHSQDALYNLLDCIQELFTHIRQAVPDAQCPHAFLQSLFVFQFRPFVLKHQQGVTLFLDGLQTSLPPVISLANLGDKLCRLEFEYDSEGDFVRVPVAPPEQPPHVHLSHFKKTIQTIEQATREATVAMTTIAKPIYPAYIRLLQRLEYLNRLNHHILRIPFPQDALSELQETYLAAFARLTKLAADAANTCSYSLTKYFGVLFQHQLVPTAIVKKLLHFDEAKDTTEAFLQSLAQPVVQGQRQGAAGGSGVLTQKELELLNKINPQFTDAQANIPPSIKRSYSNKYDVPEVSVDWETYSRSAFEAPDDELRFVPLTLAGLRKLFVE 35342FC1B0BC3B22 q76rg7_hhv8 Envelope glycoprotein L ORF47 ORF46 gL HHV8GK18_gp49 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MGIFALFAVLWTTLLVTSHAYVALPCCAIQASAASTLPLFFAVHSIHFADPNHCNGVCIAKLRSKTGDITVETCVNGFNLRSFLVAVVRRLGSWASQENLRLLWYLQRSLTAYTVGFNATTADSSIHNVNIIIISVGKAMNRTGSVSGSQTRAKSSSRRAHAGQKGK F711D54C707A8106 orf52_hhv8p Tegument protein ORF52 ORF52 protein protein hhv8p Human herpesvirus 8 Kaposi's sarcoma-associated herpesvirus HHV-8 MAAPRGRPKKDLTMEDLTAKISQLTVENRELRKALGSTADPRDRPLTATEKEAQLTATVGALSAAAAKKIEARVRTIFSKVVTQKQVDDALKGLSLRIDVCMSDGGTAKPPPGANNRRRRGASTTRAGVDD CE3399C0C1D143D9 q76rf4_hhv8 Small capsomere-interacting protein ORF65 SCP HHV8GK18_gp76 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MSNFKVRDPVIQERLDHDYAHHPLVARMNTLDQGNMSQAEYLVQKRHYLVFLIAHHYYEAYLRRMGGIQRRDHLQTLRDQKPRERADRVSAASAYDAGTFTVPSRPGPASGTTPGGQDSLGVSGSSITTLSSGPHSLSPASDILTTLSSTTETAAPAVADARKPPSGKKK 0B8620E9547FF42A orf11_hhv8p Protein ORF11 ORF11 protein protein hhv8p Human herpesvirus 8 Kaposi's sarcoma-associated herpesvirus HHV-8 MAQESEQCSRAFAVCSSKRQLGRGEPVWDSVIHPSHIVISNRVPLLLREQNICLPSCPSVGQILHRAYPNFTFDNTHRKQQTETYTAFYAFGDQNNKVRILPTVVESSSSVLIFRLRASVSANIAVGGLKIIILALTLVHAQGVYLRCGKDLSTPHCAPAIVQREVLSSGFEPQFTVTGIPVTSSNLNQCYFLVRKPKSRLAKPFARLSAETTEECRVRSIRLGKTHLRISVTAPAQETPVWGLVTTSFSLTPTAPLAFDRNPYNHETFACNARHYIPVIYSGPKITLAPRGRQVVWHNNSYTSSLPCKVTAIVSNHCCNCDIFLEDSEWRPNKPAPLKLVNTSDHPVILEPDTHIGNALFIIAPKARGLRRLTRLTTKTIELPGGVKIDSRKLQTFRKMYVATGRS 975F1029C482BA5C ltp_hhv8p Large tegument protein deneddylase ORF64 protein protein hhv8p Human herpesvirus 8 Kaposi's sarcoma-associated herpesvirus HHV-8 MAAQPLYMEGMASTHQANCIFGEHAGSQCLSNCVMYLASSYYNSETPLVDRASLDDVLEQGMRLDLLLRKSGMLGFRQYAQLHHIPGFLRTDDWATKIFQSPEFYGLIGQDAAIREPFIESLRSVLSRNYAGTVQYLIIICQSKAGAIVVKDKTYYMFDPHCIPNIPNSPAHVIKTNDVGVLLPYIATHDTEYTGCFLYFIPHDYISPEHYIANHYRTIVFEELHGPRMDISRGVESCSITEITSPSVSPAPSEAPLRRDSTQSQDETRPRRPRVVIPPYDPTDRPRPPHQDRPPEQAAGYGGNKGRGGNKGRGGKTGRGGNEGRGGHQPPDEHQPPHITAEHMDQSDGQGADGDMDSTPANGETSVTETPGPEPNPPARPDREPPPTPPATPGATALLSDLTATRGQKRKFSSLKESYPIDSPPSDDDDVSQPSQQTAPDTEDIWIDDPLTPLYPLTDTPSFDITADVTPDNTHPEKAADGDFTNKTTSTDADRYASASQESLGTLVSPYDFTNLDTLLAELGRLGTAQPIPVIVDRLTSRPFREASALQAMDRILTHVVLEYGLVSGYSTAAPSKCTHVLQFFILWGEKLGIPTEDAKTLLESALEIPAMCEIVQQGRLKEPTFSRHIISKLNPCLESLHATSRQDFKSLIQAFNAEGIRIASRERETSMAELIETITARLKPNFNIVCARQDAQTIQDGVGLLRAEVNKRNAQIAQEAAYFENIITALSTFQPPPQSQQTFEVLPDLKLRTLVEHLTLVEAQVTTQTVESLQAYLQSAATAEHHLTNVPNVHSILSNISNTLKVIDYVIPKFIINTDTLAPYKQQFSYLGGELASMFSLDWPHAPAEAVEPLPVLTSLRGKIAEALTRQENKNAVDQILTDAEGLLKNITDPNGAHFHAQAVSIPVLENYVHNAGVLLKGEKSERFSRLKTAIQNLVSSESFITVTLHSTNLGNLVTNVPKLGEAFTGGPHLLTSPSVRQSLSTLCTTLLRDALDALEKKDPALLGEGTTLALETLLGYGSVQDYKETVQIISSLVGIQKLVRDQGADKWATAVTRLTDLKSTLATTAIETATKRKLYRLIQRDLKEAQKHETNRAMEEWKQKVLALDNASPERVATLLQQAPTAKAREFAEKHFKILLPVPADAPVQASPTPMEYSASPLPDPKDIDRATSIHGEQAWKKIQQAFKDFNFAVLRPADWDALAAEYQRRGSPLPAAVGPALSGFLETILGTLNDIYMDKLRSFLPDAQPFQAPPFDWLTPYQDQVSFFLRTIGLPLVRALADKISVQALRLSHALQSGDLQQATVGTPLELPATEYARIASNMKSVFNDHGLQVRSEVADYVEAQRADAHTPHVPRPKIQAPKTLIPHPDAIVADGLPAFLKTSLLQQEAKLLALQRADFESLESDMRAAEAQRKASREETQRKMAHAITQLLQQAPSAISGRPLSLQDPVGFLEGIIYDKVLERESYETGLEGLSWLEQTIKSITVYAPVEEKQRMHVLLDEVKKQRANTETALELEAAATHGDDARLLQRAVDELSPLRVKGGKAAVESWRQKIQTLKSLVQEAEQAGLLLATIDTVAGQAQETISPSTLQGLYQQGQEAMAAIKRFRDSPQLAGLQEKLAELQQYVKYKKQYLEHFEATQSVVFTAFPLTQEVTIPALHYAGPFDNLERLSRYLHIGQTQPAPGQWLLTLPTFDPTRPACVPAGGHEPPLHRQVVFSSFLEAQIRLALSVAGPVPGRGLPGTPQIRRGVEAAACFLHQWDEISRLLPEVLDTFFHNAPLPAESSSNAFLAMCVLTHLVYLAGRAVLGPREPEHAAPDAYPREVALAPRDLTYLLLAMWPSWISAILKQPSHAEAAHACLVTLPTMLKAVPYLTLEASAGPLPADMRHFATPEARLFFPARWHHVNVQEKLWLRNDFMSLCHRSPGRARIAVLVWAVTCLDPEVIRQLWSTLRPLTADESDTASGLLRVLVEMEFGPPPKTPRREAVAPGATLPPYPYGLATGERLVGQAQERSGGAGKMPVSGFEIVLGALLFRAPLRIFSTASTHRISDFEGGFQILTPLLDCCPDREPFASLAAAPRRTVPLGDPCANIHTPEEIQIFARQAAWLQYTFANYQIPSTDNPIPIVVLNANNNLENSYIPRDRKADPLRPFYVVPLKPQGRWPEIMTTATTPCRLPTSPEEAGSQFARLLQSQVSATWSDIFSRVPERLAPNAPQKSSQTMSEIHEVAATPPLTITPNKPTGTPHVSPEADPITERKRGQQPKIVADNMPSRILPSLPTPKPREPRITLPHALPVISPPAHRPSPIPHLPAPQVTEPKGVLQSKRGTLVLRPAAVIDPRKPVSAPITRYERTALQPPRTEGEGRRPPDTQPVTLTFRLPPTAPTPATAALETKTTPPSTPPHAIDISPPQTPPMSTSPHARDTSPPAEKRAAPVIRVMAPTQPSGEARVKRVEIEQGLSTRNEAPPLERSNHAVPAVTPRRTVAREIRIPPEIKAGWDTAPDIPLPHSSPESSPPTSPQPIRVDDKSPLPNLVERYARGFLDTPSVEVMSLENQDIAVDPGLLTRRIPSVVPMPHPIMWSPIVPISLQNTDIDTAKITLISFIRRIKQKVAALSASLAETVDRIKKWYL 00070132EA8139AF q98143_hhv8 Thymidine kinase ORF21 TK protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAEGGFGADSVGRGGEKASVTRGGRWDLGSSDDESSTSTTSTDMDDLPEERKPLTGKSVKTSYIYDVPTVPTSKPWHLMHDNSLYATPRFPPRPLIRHPSEKGSIFASRLSATDDDSGDYAPMDRFAFQSPRVCGRPPLPPPNHPPPATRPADASMGDVGWADLQGLKRTPKGFLKTSTKGGSLKARGRDVGDRLRDGGFAFSPRGVKSAIGQNIKSWLGIGESSATAVPVTTQLMVPVHLIRTPVTVDYRNVYLLYLEGVMGVGKSTLVNAVCGILPQERVTSFPEPMVYWTRAFTDCYKEISHLMKSGKAGDPLTSAKIYSCQNKFSLPFRTNATAILRMMQPWNVGGGSGRGTHWCVFDRHLLSPAVVFPLMHLKHGRLSFDHFFQLLSIFRATEGDVVAILTLSSAESLRRVRARGRKNDGTVEQNYIRELAWAYHAVYCSWIMLQYITVEQMVQLCVQTTNIPEICFRSVRLAHKEETLKNLHEQSMLPMITGVLDPVRHHPVVIELCFCFFTELRKLQFIVADADKFHDDVCGLWTEIYRQILSNPAIKPRAINWPALESQSKAVNHLEETCRV C34E41D6B181DAFB q77uu3_hhv8 Envelope glycoprotein B ORF8 gB protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MTPRSRLATLGTVILLVCFCAGAAHSRGDTFQTSSSPTPPGSSSKAPTKPGEEASGPKSVDFYQFRVCSASITGELFRFNLEQTCPDTKDKYHQEGILLVYKKNIVPHIFKVRRYRKIATSVTVYRGLTESAITNKYELPRPVPLYEISHMDSTYQCFSSMKVNVNGVENTFTDRDDVNTTVFLQPVEGLTDNIQRYFSQPVIYAEPGWFPGIYRVRTTVNCEIVDMIARSAEPYNYFVTSLGDTVEVSPFCYNESSCSTTPSNKNGLSVQVVLNHTVVTYSDRGTSPTPQNRIFVETGAYTLSWASESKTTAVCPLALWKTFPRSIQTTHEDSFHFVANEITATFTAPLTPVANFTDTYSCLTSDINTTLNASKAKLASTHVPNGTVQYFHTTGGLYLVWQPMSAINLTHAQGDSGNPTSSPPPSASPMTTSASRRKRRSASTAAAGGGGSTDNLSYTQLQFAYDKLRDGINQVLEELSRAWCREQVRDNLMWYELSKINPTSVMTAIYGRPVSAKFVGDAISVTECINVDQSSVNIHKSLRTNSKDVCYARPLVTFKFLNSSNLFTGQLGARNEIILTNNQVETCKDTCEHYFITRNETLVYKDYAYLRTINTTDISTLNTFIALNLSFIQNIDFKAIELYSSAEKRLASSVFDLETMFREYNYYTHRLAGLREDLDNTIDMNKERFVRDLSEIVADLGGIGKTVVNVASSVVTLCGSLVTGFINFIKHPLGGMLMIIIVIAIILIIFMLSRRTNTIAQAPVKMIYPDVDRRAPPSGGAPTREEIKNILLGMHQLQQEERQKADDLKKSTPSVFQRTANGLRQRLRGYKPLTQSLDISPETGE C44A5F2FF29B1E41 d0uzu4_hhv8 ORF75 HHV8GK18_gp86 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAYDVTGLWLESDLTADEEAFVSFYTSRTGTLTLVPGGTGGYYLLWITFRRPPTSREERERRDVEIQTVLAVLSPLLGYPHVIRRSPPRGSERVVSFGYGPNINHRPTTLSTELGVLLRELGLQEWARVEVGRHLVSKITQTLLEPHPPQFIRAFTQNTDLVPYEGLEVPEGPQPVARPHIEDDVIMQAVMISLGADLLPLAVQASTGDNYNVARYFVIPGRCTMERWPWNCARQAFGIHGAYTHVHSSVQRGIRGLGNLLFHSTLFPGGQTQGALTGLYATEPALGPRAHSRFRRIFAKGVQQAEMLQGAGVPTLGGFLKTVRTIATTPGNALAVCSISTTTSKECISLRRMIPQQTVVCLGRFEPTDGPDTYPNLYRDSSDNAVRILETLKLVQRLAKGPIFSGLNRSHDPAPVVRHLQALAPRTGLELFVSKLPDEVRAHLPADPAAGPDAVEAAVAEHFLNVYCSLVFAVVAESGAVPGDLGETPLEVLQRAARLCACQITVLGRTSEQPGIRIVDDLTGETTRVFSVDQPSSTPPSPWLALSDGVRVSGHPEDVDWGLFATGSTIHQLLRHATVGSKEFFTRHMDRCSNGLIAQQAGVGPLDIPVSDYHLVLHSSMLAERVAPRVPDTVEAITPSMANLLHKDFETWVKALPQELLPVPAWRGQAMAMGEQAYKMATNVSTGATYAITEALTNLMFSPVSKLQDVVLTGAVAWSPEDHQAGLLQECLFACKEFCRELGVALSISSAASSPTLSERHVRITQQQETVEVLPFNSVVFTSWAEVKGSRYRVTPDVKVEGNALVYLAVNQSCLIAGSTFEHNFLASRHPIPPLNPSTVASLFMLVKYLMSKRLIVSGHDIGDGGLLPSAIEMALAGCRGLQLSLPAHPNPLELMVSETPGALVEVPQVHLSEVLRAARDYRCVAHPLGTVGPEGQGNNVTVLQNETVVFQETLTSLQVSWTSFSDEMWNLVTPPLHPLEDMHRKDLGRLEHHLGSLRAMCLGSQLRLFSCPTSPRRVAALVLPGSSAPYALMAALQNTGFEVATVTVEELKRGQSLSGFSGLITCLRTGCQASYASARGWVLALCNDPTCASTLTEFLNRPDTFSICCGEVGFQLLVALGVVGRSESSPYTYGPTPPQRWAVNLETNVSKLYDSHWLNIQIPQNTKSVFLRVLRGTVLPSWAQGEYLGVRYEQDALEYILRQRGEITLTYHGNAADETLPARHYPRNPTGNSTVAGLTSSDGRHAALIIDPSLMFHPWQWQHVPPDLTPLSMSPWAMAFQSIYLWSVKKINDHH 322832D4C1F23585 q76rg4_hhv8 ORF53 HHV8GK18_gp57 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MTASTVALALFVASILGHCWVTANSTGVASSTERSSPSTAGLSARPSPGPTSVTTPGFYDVACSADSFSPSLSSFSSVWALINALLVVVATFFYLVYLCFFKFVDEVVHA 468877D25B4B0173 q76rf6_hhv8 Triplex capsid protein 1 ORF62 TRX1 HHV8GK18_gp69 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MKVQAENAARLGRQVLGLLPPPTHRVSLTRGPEFARGVRDLLSKYAASTRPTVGSLHEALRQAPFRQPTYGDFLVYSQTFSPQEPLGTFLFSFKQEDNGSSMDMLLTPTSLFMLSGMEAAKAPQTHKVAGVWYGSGSGLADFIPNLSELMDTGEFHTLLTPVGPMVQSVHSTFVTKVTSAMKGVGLARDEPRAHVGLTLPCDMLVDLDESCPMVQRREPAGLNVTIYASLVYLRVNQRPSMALTFFQSGKGFAEVVAMIKDHFTDVIRTKYIQLRHELYINRLVFGAVCTLGTVPFDSHPVHQSLNVKGTSLPVLVFANFEAACGPWTVFL 91113380F7C0B7FB o40917_hhv8 ORF11 HHV8GK18_gp08 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAQESEQCSRAFAVCSSKRQLGRGEPVWDSVIHPSHIVISNRVPLLLREQHICLPSCPSVGQILHRAYPNFTFDNTHRKQQTETYTAFYAFGDQNNKVRILPTVVESSSSVLIFRLRASVSANIAVGGLKIIILALTLVHAQGVYLRCGKDLSTPHCAPAIVQREVLSSGFEPQFTVTGIPVTSSNLNQCYFLVRKPKSRLAKPFARLSAETTEECRVRSIRLGKTHLRISVTAPAQETPVWGLVTTSFSLTPTAPLAFDRNPYNHETFACNARHYIPVIYSGPKITLAPRGRQVVWHNNSYTSSLPCKVTAIVSNHCCNCDIFLEDSEWRPNKPAPLKLVNTSDHPVILEPDTHIGNALFIIAPKARGLRRLTRLTTKTIELPGGVKIDSRKLQTFRKMYVATGRS 7C54C20686FB0027 o40942_hhv8 Large tegument protein deneddylase protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAAQPLYMEGMASTHQANCIFGEHAGSQCLSNCVMYLASSYYNSETPLVDRASLDDVLEQGMRLDLLLRKSGMLGFRQYAQLHHIPGFLRTDDWATKIFQSPEFYGLIGQDAAIREPFIESLRSVLSRNYAGTVQYLIIICQSKAGAIVVKDKTYYMFDPHCIPNIPNSPAHVIKTNDVGVLLPYIATHDTEYTGCFLYFIPHDYISPEHYIANHYRTIVFEELHGPRMDISRGVESCSITEITSPSVSPAPSEAPLRRDSTQSQDETRPRRPRVVIPPYDPTDRPRPPHQDRPPEQAAGYGGNKGRGGNKGRGGKTGRGGNEGRGGHQPPDEHQPPHITAEHMDQSDGQGADGDMDSTPANGETSVTETPGPEPNPPARPDREPPPTPPATPGATALLSDLTATRGQKRKFSSLKESYPIDSPPSDDDDVSQPSQQTAPDTEDIWIDDPLTPLYPLTDTPSFDITADVTPDNTHPEKAADGDFTNKTTSTDADRYASASQESLGTLVSPYDFTNLDTLLAELGRLGTAQPIPVIVDRLTSRPFREASALQAMDRILTHVVLEYGLVSGYSTAAPSKCTHVLQFFILWGEKLGIPTEDAKTLLESALEIPAMCEIVQQGRLKEPTFSRHIISKLNPCLESLHATSRQDFKSLIQAFNAEGIRIASRERETSMAELIETITARLKPNFNIVCARQDAQTIQDGVGLLRAEVNKRNAQIAQEAAYFENIITALSTFQPPPQSQQTFEVLPDLKLRTLVEHLTLVEAQVTTQTVESLQAYLQSAATAEHHLTNVPNVHSILSNISNTLKVIDYVIPKFIINTDTLAPYKQQFSYLGGELASMFSLDWPHAPAEAVEPLPVLTSLRGKIAEALTRQENKNAVDQILTDAEGLLKNITDPNGAHFHAQAVSIPVLENYVHNAGVLLKGEKSERFSRLKTAIQNLVSSESFITVTLHSTNLGNLVTNVPKLGEAFTGGPHLLTSPSVRQSLSTLCTTLLRDALDALEKKDPALLGEGTTLALETLLGYGSVQDYKETVQIISSLVGIQKLVRDQGADKWATAVTRLTDLKSTLATTAIETATKRKLYRLIQRDLKEAQKHETNRAMEEWKQKVLALDNASPERVATLLQQAPTAKAREFAEKHFKILLPVPADAPVQASPTPMEYSASPLPDPKDIDRATSIHGEQAWKKIQQAFKDFNFAVLRPADWDALAAEYQRRGSPLPAAVGPALSGFLETILGTLNDIYMDKLRSFLPDAQPFQAPPFDWLTPYQDQVSFFLRTIGLPLVRALADKISVQALRLSHALQSGDLQQATVGTPLELPATEYARIASNMKSVFNDHGLQVRSEVADYVEAQRADAHTPHVPRPKIQAPKTLIPHPDAIVADGLPAFLKTSLLQQEAKLLALQRADFESLESDMRAAEAQRKASREETQRKMAHAITQLLQQAPSAISGRPLSLQDPVGFLEGIIYDKVLERESYETGLEGLSWLEQTIKSITVYAPVEEKQRMHVLLDEVKKQRANTETALELEAAATHGDDARLLQRAVDELSPLRVKGGKAAVESWRQKIQTLKSLVQEAEQAGLLLATIDTVAGQAQETISPSTLQGLYQQGQEAMAAIKRFRDSPQLAGLQEKLAELQQYVKYKKQYLEHFEATQSVVFTAFPLTQEVTIPALHYAGPFDNLERLSRYLHIGQTQPAPGQWLLTLPTFDPTRPACVPAGGHEPPLHRQVVFSSFLEAQIRLALSVAGPVPGRGLPGTPQIRRGVEAAACFLHQWDEISRLLPEVLDTFFHNAPLPAESSSNAFLAMCVLTHLVYLAGRAVLGPREPEHAAPDAYPREVALAPRDLTYLLLAMWPSWISAILKQPSHAEAAHACLVTLPTMLKAVPYLTLEASAGPLPADMRHFATPEARLFFPARWHHVNVQEKLWLRNDFMSLCHRSPGRARIAVLVWAVTCLDPEVIRQLWSTLRPLTADESDTASGLLRVLVEMEFGPPPKTPRREAVAPGATLPPYPYGLATGERLVGQAQERSGGAGKMPVSGFEIVLGALLFRTPLRIFSTASTHRISDFEGGFQILTPLLDCCPDREPFASLAAAPRRTVPLGDPCANIHTPEEIQIFARQAAWLQYTFANYQIPSTDNPIPIVVLNANNNLENSYIPRDRKADPLRPFYVVPLKPQGRWPEIMTTATTPCRLPTSPEEAGSQFARLLQSQVSATWSDIFSRVPERLAPNAPQKSSQTMSEIHEVAATPPLTITPNKPTGTPHVSPEADPITERKRGQQPKIVADNMPSRILPSLPTPKPREPRITLPHALPVISPPAHRPSPIPHLPAPQVTEPKGVLQSKRGTLVLRPAAVIDPRKPVSAPITRYERTALQPPRTEGEGRRPPDTQPVTLTFRLPPTAPTPATAALETKTTPPSTPPHAIDISPPQTPPMSTSPHARDTSPPAEKRAAPVIRVMAPTQPSGEARVKRVEIEQGLSTRNEAPPLERSNHAVPAVTPRRTVAREIRIPPEIKAGWDTAPDIPLPHSSPESSPPTSPQPIRVDDKSPLPNLVERYARGFLDTPSVEVMSLENQDIAVDPGLLTRRIPSVVPMPHPIMWSPIVPISLQNTDIDTAKITLISFIRRIKQKVAALSASLAETVDRIKKWYL 91DDA0D6FF7B660A q77uv9_hhv8 ORF45 KIE-2 HHV8GK18_gp51 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAMFVRTSSSTHDEERMLPIEGAPRRRPPVKFIFPPPPLSSLPGFGRPRGYAGPTVIDMSAPDDVFAEDTPSPPATPLDLQISPDQSSGESEYDEDEEDEDEEENDDVQEEDEPEGYPADFFQPLSHLRPRPLARRAHTPKPVAVVAGRVRSSTDTAESEASMGWVSQDDGFSPAGLSPSDDEGVAILEPMAAYTGTGAYGLSPASRNSVPGTQSSPYSDPDEGPSWRPLRAAPTAIVDLTSDSDSDDSSNSPDVNNEAAFTDARHFSHQPPSSEEDGEDQGEVLSQRIGLMDVGQKRKRQSTASSGSEDVVRCQRQPNLSRKAVASVIIISSGSDTDEEPSSAVSVIVSPSSTKGHLPTQSPSTSAHSISSGSTTTAGSRCSDPTRILASTPPLCGNGAYNWPWLD F8F5876EFDA2BB35 c7e599_hhv8 Triplex capsid protein 2 ORF26 TRX2 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MALDKSIVVNFTSRLFADELAALQSKIGSVLPLGDCHRLQNIQALGLGCVCSRETSPDYIQIMQYLSKCTLAVLEEVRPDSLRLTRMDPSDNLQIKNVYAPFFQWDSNTQLAVLPPFFSRKDSTIVLESNGFDLVFPMVVPQQLGHAILQQLLVYHIYSKISAGAPDDVNMAELDLYTTNVSFMGRTYRLDVDNTDPRTALRVLDDLSMYLCILSALVPRGCLRLLTALVRHDRHPLTEVFEGVVPDEVTRIDLDQLSVPDDITRMRVMFSYLQSLSSIFNLGPRLHVYAYSAETLAASCWYSPR 5C5D9E83C24902BD d0uzn7_hhv8 Major capsid protein ORF25 HHV8GK18_gp29 MCP protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MEATLEQRPFPYLATEANLLTQIKESAADGLFKSFQLLLGKDAREGSVRFEALLGVYTNVVEFVKFLETALAAACVNTEFKDLRRMIDGKIQFKISMPTIAHGDGRRPNKQRQYIVMKACNKHHIGAEIELAAADIELLFAEKETPLDFTEYAGAIKTITSALQFGMDALERGLVDTVLAVKLRHAPPVFILKTLGDPVYSERGLKKAVKSDMVSMFKAHLIEHSFFLDKAELMTRGKQYVLTMLSDMLAAVCEDTVFKGVSTYTTASGQQVAGVLETTDSVMRRLMNLLGQVESAMSGPAAYASYVVRGANLVTAVSYGRAMRNFEQFMARIVDHPNALPSVEGDKAALADGHDEIQRTRIAASLVKIGDKFVAIESLQRMYNETQFPCPLNRRIQYTYFFPVGLHLPVPRYSTSVSVRGVESPAIQSTETWVVNKNNVPLCFGYQNALKSICHPRMHNPTQSAQALNQAFPDPDGGHGYGLRYEQTPNMNLFRTFHQYYMGKNVAFVPDVAQKALVTTEDLLHPTSHRLLRLEVHPFFDFFVHPCPGARGSYRATHRTMVGNIPQPLAPREFQESRGAQFDAVTNMTHVIDQLTIDVIQETAFDPAYPLFCYVIEAMIHGQEEKFVMNMPLIALVIQTYWVNSGKLAFVNSYHMVRFICTHMGNGSIPKEAHGHYRKILGELIALEQALLKLAGHETVGRTPITHLVSALLDPHLLPPFAYHDVFTDLMQKSSRQPIIKIGDQNYDNPQNRATFINLRGRMEDLVNNLVNIYQTRVNEDHDERHVLDVAPLDENDYNPVLEKLFYYVLMPVCSNGHMCGMGVDYQNVALTLTYNGPVFADVVNAQDDILLHLENGTLKDILQAGDIRPTVDMIRVLCTSFLTCPFVTQAARVITKRDPAQSFATHEYGKDVAQTVLVNGFGAFAVADRSREAAETMFYPVPFNKLYADPLVAATLHPLLANYVTRLPNQRNAVVFNVPSNLMAEYEEWHKSPVAAYAASCQATPGAISAMVSMHQKLSAPSFICQAKHRMHPGFAMTVVRTDEVLAEHILYCSRASTSMFVGLPSVVRREVRSDAVTFEITHEIASLHTALGYSSVIAPAHVAAITTDMGVHCQDLFMIFPGDAYQDRQLHDYIKMKAGVQTGPPGNRMDHVGYAAGVPRCENLPGLSHGQLATCEIIPTPVTSDVAYFQTPSNPRGRAACVVSCDAYSNESAERLLYDHSIPDPAYECRSTNNPWASQRGSLGDVLYNITFRQTALPGMYSPCRQFFHKEDIMRYNRGLYTLVNEYSARLAGAPATSTTDLQYVVVNGTDVFLDQPCHMLQEAYPTLAASHRVMLDEYMSNKQTHAPVHMGQYLIEEVAPMKRLLKLGNKVVY 0F2CEC46FADA0A30 o40929_hhv8 Cytoplasmic envelopment protein 2 ORF33 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MASRRRKLRNFLNKECIWTVNPMSGDHIKVFNACTSISPVYDPELVTSYALSVPAYNVSVAILLHKVMGPCVAVGINGEMIMYVVSQCVSVRPVPGRDGMALIYFGQFLEEASGLRFPYIAPPPSREHVPDLTRQELVHTSQVVRRGDLTNCTMGLEFRNVNPFVWLGGGSVWLLFLGVDYMAFCPGVDGMPSLARVAALLTRCDHPDCVHCHGLRGHVNVFRGYCSAQSPGLSNICPCIKSCGTGNGVTRVTGNRNFLGLLFDPIVQSRVTALKITSHPTPTHVENVLTGVLDDGTLVPSSKAPWVLLRMSDYFSRLLIYECKKLKALGLRSY 2B7F1CC59A6D378D q98138_hhv8 ORF27 HHV8GK18_gp31 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MASSDILSVARTDDGSVCEVSLRGGRKKTTVYLPDTEPWVVETDAIKDAFLSDGIVDMARKLHRGALPSNSHNGLRMVLFCYCYLQNCVYLALFLCPLNPYLVTPSSIEFAEPVVAPEVLFPHPAEMSRGCDDAIFCKLPYTVPIINTTFGRIYPNSTREPDGRPTDYSMALRRAFAVMVNTSCAGVTLCRGETQTASRNHTEWENLLAMFSVIIYALDHNCHPEALSIASGIFDERDYGLFISQPRSVPSPTPCDVSWEDIYNGTYLARPGNCDPWPNLSTPPLILNFK 1F26E152B98EE965 d0uzt1_hhv8 Large tegument protein deneddylase ORF64 HHV8GK18_gp72 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MAAQPLYMEGMASTHQANCIFGEHAGSQCLSNCVMYLASSYYNSETPLVDRASLDDVLEQGMRLDLLLRKSGMLGFRQYAQLHHIPGFLRTDDWATKIFQSPEFYGLIGQDAAIREPFIESLRSVLSRNYAGTVQYLIIICQSKAGAIVVKDKTYYMFDPHCIPNIPNSPAHVIKTNDVGVLLPYIATHDTEYTGCFLYFIPHDYISPEHYIANHYRTIVFEELHGPRMDISRGVESCSITEITSPSVSPAPSEAPLRRDSTQSQDETRPRRPRVVIPPYDPTDRPRPPHQDRPPEQAAGYGGNKGRGGNKGRGGKTGRGGNEGRGGHQPPDEHQPPHITAEHMDQSDGQGADGDMDSTPANGETSVTETPGPEPNPPARPDREPPPTPPATPGATALLSDLTATRGQKRKFSSLKESYPIDSPPSDDDDVSQPSQQTAPDTEDIWIDDPLTPLYPLTDTPSFDITADVTPDNTHPEKAADGDFTNKTTSTDADRYASASQESLGTLVSPYDFTNLDTLLAELGRLGTAQPIPVIVDRLTSRPFREASALQAMDRILTHVVLEYGLVSGYSTAAPSKCTHVLQFFILWGEKLGIPTEDAKTLLESALEIPAMCEIVQQGRLKEPTFSRHIISKLNPCLESLHATSRQDFKSLIQAFNAEGIRIASRERETSMAELIETITARLKPNFNIVCARQDAQTIQDGVGLLRAEVNKRNAQIAQEAAYFENIITALSTFQPPPQSQQTFEVLPDLKLRTLVEHLTLVEAQVTTQTVESLQAYLQSAATAEHHLTNVPNVHSILSNISNTLKVIDYVIPKFIINTDTLAPYKQQFSYLGGELASMFSLDWPHAPAEAVEPLPVLTSLRGKIAEALTRQENKNAVDQILTDAEGLLKNITDPNGAHFHAQAVSIPVLENYVHNAGVLLKGEKSERFSRLKTAIQNLVSSESFITVTLHSTNLGNLVTNVPKLGEAFTGGPHLLTSPSVRQSLSTLCTTLLRDALDALEKKDPALLGEGTTLALETLLGYGSVQDYKETVQIISSLVGIQKLVRDQGADKWATAVTRLTDLKSTLATTAIETATKRKLYRLIQRDLKEAQKHETNRAMEEWKQKVLALDNASPERVATLLQQAPTAKAREFAEKHFKILLPVPADAPVQASPTPMEYSASPLPDPKDIDRATSIHGEQAWKKIQQAFKDFNFAVLRPADWDALAAEYQRRGSPLPAAVGPALSGFLETILGTLNDIYMDKLRSFLPDAQPFQAPPFDWLTPYQDQVSFFLRTIGLPLVRALADKISVQALRLSHALQSGDLQQATVGTPLELPATEYARIASNMKSVFNDHGLQVRSEVADYVEAQRADAHTPHVPRPKIQAPKTLIPHPDAIVADGLPAFLKTSLLQQEAKLLALQRADFESLESDMRAAEAQRKASREETQRKMAHAITQLLQQAPSAISGRPLSLQDPVGFLEGIIYDKVLERESYETGLEGLSWLEQTIKSITVYAPVEEKQRMHVLLDEVKKQRANTETALELEAAATHGDDARLLQRAVDELSPLRVKGGKAAVESWRQKIQTLKSLVQEAEQAGLLLATIDTVAGQAQETISPSTLQGLYQQGQEAMAAIKRFRDSPQLAGLQEKLAELQQYVKYKKQYLEHFEATQSVVFTAFPLTQEVTIPALHYAGPFDNLERLSRYLHIGQTQPAPGQWLLTLPTFDPTRPACVPAGGHEPPLHRQVVFSSFLEAQIRLALSVAGPVPGRGLPGTPQIRRGVEAAACFLHQWDEISRLLPEVLDTFFHNAPLPAESSSNAFLAMCVLTHLVYLAGRAVLGPREPEHAAPDAYPREVALAPRDLTYLLLAMWPSWISAILKQPSHAEAAHACLVTLPTMLKAVPYLTLEASAGPLPADMRHFATPEARLFFPARWHHVNVQEKLWLRNDFMSLCHRSPGRARIAVLVWAVTCLDPEVIRQLWSTLRPLTADESDTASGLLRVLVEMEFGPPPKTPRREAVAPGATLPPYPYGLATGERLVGQAQERSGGAGKMPVSGFEIVLGALLFRAPLRIFSTASTHRISDFEGGFQILTPLLDCCPDREPFASLAAAPRRTVPLGDPCANIHTPEEIQIFARQAAWLQYTFANYQIPSTDNPIPIVVLNANNNLENSYIPRDRKADPLRPFYVVPLKPQGRWPEIMTTATTPCRLPTSPEEAGSQFARLLQSQVSATWSDIFSRVPERLAPNATQKSSQTMSEIHEVAATPPLTITPNKPTGTPHVSPEADPITERKRGQQPKIVADNMPSRILPSLPTPKPREPRITLPHALPVISPPAHRPSPIPHLPAPQVTEPKGVLQSKRGTLVLRPAAVIDPRKPVSAPITRYERTALQPPRTEGEGRRPPDTQPVTLTFRLPPTAPTPATAALETKTTPPSTPPHAIDISPPQTPPMSTSPHARDTSPPAEKRAAPVIRVMAPTQPSGEARVKRVEIEQGLSTRNEAPPLERSNHAVPAVTPRRTVAREIRIPPEIKAGWDTAPDIPLPHSSPESSPPTSPQPIRVDDKSPLPNLVERYARGFLDTPSVEVMSLENQDIAVDPGLLTRRIPSVVPMPHPIMWSPIVPISLQNTDIDTAKITLISFIRRIKQKVAALSASLAETVDRIKKWYL 73D3C989C9841616 q98142_hhv8 Envelope glycoprotein H ORF22 gH HHV8GK18_gp26 protein protein hhv8 Human herpesvirus 8 (HHV-8) Kaposi's sarcoma-associated herpesvirus HHV-8 MQGLAFLAALACWRCISLTCGATGALPTTATTITRSATQLINGRTNLSIELEFNGTSFFLNWQNLLNVITEPALTELWTSAEVAEDLRVTLKKRQSLFFPNKTVVISGDGHRYTCEVPTSSQTYNITKGFNYSALPGHLGGFGINARLVLGDIFASKWSLFARDTPEYRVFYPMNVMAVKFSISIGNNESGVALYGVVSEDFVVVTLHNRSKEANETASHLLFGLPDSLPSLKGHATYDELTFARNAKYALVAILPKDSYQTLLTENYTRIFLNMTESTPLEFTRTIQTRIVSIEARRACAAQEAAPDIFLVLFQMLVAHFLVARGIAEHRFVEVDCVCRQYAELYFLRRISRLCMPTFTTVGYNHTTLGAVAATQIARVSATKLASLPRSSQETVLAMVQLGARDGAVPSSILEGIAMVVEHMYTAYTYVYTLGDTERKLMLDIHTVLTDSCPPKDSGVSEKLLRTYLMFTSMCTNIELGEMIARFSKPDSLNIYRAFSPCFLGLRYDLHPAKLRAEAPQSSALTRTAVARGTSGFAELLHALHLDSLNLIPAINCSKITADKIIATVPLPHVTYIISSEALSNAVVYEVSEIFLKSAMFISAIKPDCSGFNFSQIDRHIPIVYNISTPRRGCPLCDSVIMSYDESDGLQSLMYVTNERVQTNLFLDKSPFFDNNNLHIHYLWLRDNGTVVEIRGMYRRRAASALFLILSFIGFSGVIYFLYRLFSILY B5DB4B733DDFE451 orf11-orf21 2 20 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association table 2 orf11-orf47 2 20 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association table 2 orf11-orf53 2 20 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey physical association physical association table 2 orf21-orf25 2 4 unspecified role unspecified role prey prey n terminal sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf62 2 19 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf64 2 21 unspecified role unspecified role prey prey n terminal sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf25-1 1 24 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf22-1 2 28 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf47 2 15 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf21-orf53 2 15 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey physical association physical association Table 2 orf27-orf39 2 26 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey physical association physical association Table 2 orf27-orf22 2 28 unspecified role unspecified role prey prey 26 unspecified role unspecified role bait bait physical association physical association Table 2 orf27-orf47 2 26 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf27-orf53 2 18 unspecified role unspecified role prey prey 26 unspecified role unspecified role bait bait physical association physical association Table 2 orf33-orf52 1 11 unspecified role unspecified role prey prey 25 unspecified role unspecified role bait bait physical association physical association Table 2 orf33-orf8 2 16 unspecified role unspecified role prey prey 25 unspecified role unspecified role bait bait physical association physical association Table 2 orf33-orf39 2 8 unspecified role unspecified role prey prey 25 unspecified role unspecified role bait bait physical association physical association Table 2 orf33-orf22 2 28 unspecified role unspecified role prey prey 25 unspecified role unspecified role bait bait physical association physical association Table 2 orf33-orf53 2 25 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf26 2 23 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf62 2 19 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf65 2 12 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf11 2 22 unspecified role unspecified role bait bait 20 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf21 2 22 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf33 2 22 unspecified role unspecified role bait bait 25 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf63 2 9 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf64 2 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf75 2 17 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf39 2 8 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf22 2 28 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf47 2 22 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf53 2 22 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf26 2 11 unspecified role unspecified role bait bait 23 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf45 2 22 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait physical association physical association Table 2 orf52-orf64 2 21 unspecified role unspecified role prey prey n terminal sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 11 unspecified role unspecified role bait bait physical association physical association Table 2 orf52-orf75 2 11 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf39 2 11 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf47 2 11 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf53 2 18 unspecified role unspecified role prey prey 11 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf33 1 14 unspecified role unspecified role bait bait 25 unspecified role unspecified role prey prey physical association physical association Table 2 orf63-orf45 2 9 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association Table 2 orf63-orf64 2 9 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf63-orf47 2 9 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf63-orf53 2 18 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf25 2 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 4 unspecified role unspecified role prey prey n terminal sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf62 2 19 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf11 2 20 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf21-1 1 15 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf64 2 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf75 2 17 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf8 2 16 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf39 2 8 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf22 2 28 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf47 2 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 10 unspecified role unspecified role prey prey physical association physical association Table 2 orf75-orf62 2 19 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association Table 2 orf75-orf39 2 17 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey physical association physical association Table 2 orf75-orf53 2 18 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf21 1 15 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf11-orf53-1 1 20 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association table 2 orf21-orf75 1 15 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey physical association physical association Table 2 orf21-orf62-1 1 19 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf64-1 1 21 unspecified role unspecified role prey prey n terminal sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf21-orf53-1 1 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 15 unspecified role unspecified role bait bait physical association physical association Table 2 orf27-orf47-1 1 26 unspecified role unspecified role bait bait 10 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf27-orf53-1 1 26 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf33-orf8-1 1 25 unspecified role unspecified role bait bait 16 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf33-orf53-1 1 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 25 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf62-1 1 19 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf11-1 1 22 unspecified role unspecified role bait bait 20 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf21-1 1 22 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf33-1 1 22 unspecified role unspecified role bait bait 25 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf63-1 1 9 unspecified role unspecified role prey prey 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf64-1 1 22 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf45-orf75-1 1 22 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf47-1 1 10 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf53-1 1 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 22 unspecified role unspecified role bait bait physical association physical association Table 2 orf52-orf26-1 1 11 unspecified role unspecified role bait bait 23 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf52-orf45-1 1 11 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf75-1 1 11 unspecified role unspecified role bait bait 17 unspecified role unspecified role prey prey physical association physical association Table 2 orf52-orf39-1 1 8 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 11 unspecified role unspecified role bait bait physical association physical association Table 2 orf52-orf53-1 1 11 unspecified role unspecified role bait bait 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf63-orf45-1 1 9 unspecified role unspecified role bait bait 22 unspecified role unspecified role prey prey physical association physical association Table 2 orf63-orf64-1 1 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 9 unspecified role unspecified role bait bait physical association physical association Table 2 orf63-orf47-1 1 10 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 9 unspecified role unspecified role bait bait physical association physical association Table 2 orf63-orf53-1 1 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 9 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf25-1 1 4 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf62-1 1 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 19 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf64-orf64-1 1 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf75-1 1 17 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf8-1 1 16 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 21 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf39-1 1 21 unspecified role unspecified role bait bait 8 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association Table 2 orf75-orf21 1 5 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 orf75-orf39-1 1 8 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait physical association physical association Table 2 orf75-orf53-1 1 18 unspecified role unspecified role prey prey region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 17 unspecified role unspecified role bait bait physical association physical association Table 2 orf75-orf45 2 22 unspecified role unspecified role prey prey 17 unspecified role unspecified role bait bait physical association physical association Table 2 orf75-orf52 2 17 unspecified role unspecified role bait bait 11 unspecified role unspecified role prey prey physical association physical association Table 2 orf75-orf64 2 17 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf75-orf64-1 1 17 unspecified role unspecified role bait bait 21 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf45 2 22 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf45-1 1 22 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf52 2 11 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf63 1 9 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf63-1 2 9 unspecified role unspecified role prey prey 21 unspecified role unspecified role bait bait region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain physical association physical association Table 2 orf64-orf21 2 21 unspecified role unspecified role bait bait 15 unspecified role unspecified role prey prey physical association physical association Table 2 orf64-orf26 1 6 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association Table 2 orf64-orf11-1 1 13 unspecified role unspecified role prey prey 14 unspecified role unspecified role bait bait physical association physical association Table 2 orf63-orf21 1 15 unspecified role unspecified role prey prey 9 unspecified role unspecified role bait bait physical association physical association Table 2 orf45-orf27 1 22 unspecified role unspecified role bait bait 26 unspecified role unspecified role prey prey physical association physical association Table 2 orf45-orf52 1 22 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 11 unspecified role unspecified role prey prey region myc tag myc tag EUKLISEED epitope tag EUKLISEED epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association fig2 orf39-orf52 1 11 unspecified role unspecified role prey prey n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 8 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association fig3 orf39-orf64 3 27 unspecified role unspecified role prey prey 8 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 3 orf25-orf64-1 3 24 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 1 orf26-orf64 3 6 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 1 orf62-orf64 3 27 unspecified role unspecified role prey prey 19 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 1 orf11-orf64 3 27 unspecified role unspecified role prey prey 20 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 2 orf21-orf64-2 3 27 unspecified role unspecified role prey prey 15 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association 2 orf33-orf64 3 7 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 2 orf45-orf64-2 3 22 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 2 orf63-orf64-2 3 9 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 2 orf75-orf64-2 3 17 unspecified role unspecified role bait bait n terminal v5 tag v5 tag GKPIPNPLLGLDST epitope tag GKPIPNPLLGLDST epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined 27 unspecified role unspecified role prey prey physical association physical association 2 orf64-orf64-2 3 27 unspecified role unspecified role bait bait region flag tag flag tag FLAG-tagged FLAG DYKDDDDKV epitope tag DYKDDDDKV epitope tag FLAG FLAG-tagged undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 27 unspecified role unspecified role prey prey region sufficient to bind sufficient binding region sufficient to bind deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain 459 457 physical association physical association 2 This self-association suggests dimerization or multimerization of the ORF64 protein in virions or in infected cells. Since the self-association appears to involve different regions in ORF64N (amino acids 1 to 849) and ORF64M (amino acids 600 to 1931) fragments, the possibility exists that the self-association may contribute to intramolecular folding of the protein