MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it A protein domain-based interactome network for C. elegans early embryogenesis. A protein domain-based interactome network for C. elegans early embryogenesis. Cell (0092-8674) 2008 imex curation Boxem M., Maliga Z., Klitgord N., Li N., Lemmens I., Mana M., de Lichtervelde L., Mul JD., van de Peut D., Devos M., Simonis N., Yildirim MA., Cokol M., Kao HL., de Smet AS., Wang H., Schlaitz AL., Hao T., Milstein S., Fan C., Tipsword M., Drew K., Galli M., Rhrissorrakrai K., Drechsel D., Koller D., Roth FP., Iakoucheva LM., Dunker AK., Bonneau R., Gunsalus KC., Hill DE., Piano F., Tavernier J., van den Heuvel S., Hyman AA., Vidal M. A large number of interactions found by yeast two-hybrid screening in this publication were corrected by the authors in an erratum published in 2012, so they were deleted upon the authors' request and included in a new entry created for the erratum publication (IntAct accession number EBI-6455527). Check reference Boxem et al., Erratum: A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis, Cell(2012), http://dx.doi.org/10.1016/j.cell.2012.11.042. Two hybrid matrix method used. mboxem@partners.org 16-Oct-2008: Contacted by JYOTI. Literature-derived interactions were tested using a human AD-fusion cDNA library. Only protein-protein interactions 843 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast two hybrid array two hybrid array predetermined predetermined participant predetermined Boxem M., Maliga Z., Klitgord N., Li N., Lemmens I., Mana M., de Lichtervelde L., Mul JD., van de Peut D., Devos M., Simonis N., Yildirim MA., Cokol M., Kao HL., de Smet AS., Wang H., Schlaitz AL., Hao T., Milstein S., Fan C., Tipsword M., Drew K., Galli M., Rhrissorrakrai K., Drechsel D., Koller D., Roth FP., Iakoucheva LM., Dunker AK., Bonneau R., Gunsalus KC., Hill DE., Piano F., Tavernier J., van den Heuvel S., Hyman AA., Vidal M. A large number of interactions found by yeast two-hybrid screening in this publication were corrected by the authors in an erratum published in 2012, so they were deleted upon the authors' request and included in a new entry created for the erratum publication (IntAct accession number EBI-6455527). Check reference Boxem et al., Erratum: A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis, Cell(2012), http://dx.doi.org/10.1016/j.cell.2012.11.042. Two hybrid matrix method used. mboxem@partners.org Accepted 2008-NOV-2 by ORCHARD. 16-Oct-2008: Contacted by JYOTI. Literature-derived interactions were tested using a human AD-fusion cDNA library. Cell (0092-8674) 2008 Only protein-protein interactions 843 imex curation A protein domain-based interactome network for C. elegans early embryogenesis. A protein domain-based interactome network for C. elegans early embryogenesis. Cell (0092-8674) 2008 imex curation Boxem M., Maliga Z., Klitgord N., Li N., Lemmens I., Mana M., de Lichtervelde L., Mul JD., van de Peut D., Devos M., Simonis N., Yildirim MA., Cokol M., Kao HL., de Smet AS., Wang H., Schlaitz AL., Hao T., Milstein S., Fan C., Tipsword M., Drew K., Galli M., Rhrissorrakrai K., Drechsel D., Koller D., Roth FP., Iakoucheva LM., Dunker AK., Bonneau R., Gunsalus KC., Hill DE., Piano F., Tavernier J., van den Heuvel S., Hyman AA., Vidal M. A large number of interactions found by yeast two-hybrid screening in this publication were corrected by the authors in an erratum published in 2012, so they were deleted upon the authors' request and included in a new entry created for the erratum publication (IntAct accession number EBI-6455527). Check reference Boxem et al., Erratum: A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis, Cell(2012), http://dx.doi.org/10.1016/j.cell.2012.11.042. Two hybrid matrix method used. mboxem@partners.org 16-Oct-2008: Contacted by JYOTI. Literature-derived interactions were tested using a human AD-fusion cDNA library. Only protein-protein interactions 843 yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast two hybrid pooling two hybrid pooling approach two hybrid pooling predetermined predetermined participant predetermined Boxem M., Maliga Z., Klitgord N., Li N., Lemmens I., Mana M., de Lichtervelde L., Mul JD., van de Peut D., Devos M., Simonis N., Yildirim MA., Cokol M., Kao HL., de Smet AS., Wang H., Schlaitz AL., Hao T., Milstein S., Fan C., Tipsword M., Drew K., Galli M., Rhrissorrakrai K., Drechsel D., Koller D., Roth FP., Iakoucheva LM., Dunker AK., Bonneau R., Gunsalus KC., Hill DE., Piano F., Tavernier J., van den Heuvel S., Hyman AA., Vidal M. A large number of interactions found by yeast two-hybrid screening in this publication were corrected by the authors in an erratum published in 2012, so they were deleted upon the authors' request and included in a new entry created for the erratum publication (IntAct accession number EBI-6455527). Check reference Boxem et al., Erratum: A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis, Cell(2012), http://dx.doi.org/10.1016/j.cell.2012.11.042. Two hybrid matrix method used. mboxem@partners.org Accepted 2008-NOV-2 by ORCHARD. 16-Oct-2008: Contacted by JYOTI. Literature-derived interactions were tested using a human AD-fusion cDNA library. Cell (0092-8674) 2008 Only protein-protein interactions 843 imex curation fen1_human Flap endonuclease 1 Flap structure-specific endonuclease 1 Maturation factor 1 DNase IV FEN1 RAD2 protein protein human Homo sapiens Human MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQAAGAEQEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKSIEEIVRRLDPNKYPVPENWLHKEAHQLFLEPEVLDPESVELKWSEPNEEELIKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGSTKKKAKTGAAGKFKRGK DIP protein P39748 original sequence version: 106 DIP protein P39748 original sequence version: 112 DIP protein P39748 original sequence version: 160 5154F2F6E57592C5 md1l1_human Mitotic spindle assembly checkpoint protein MAD1 Mitotic arrest deficient 1-like protein 1 Mitotic checkpoint MAD1 protein homolog Tax-binding protein 181 MAD1L1 MAD1 TXBP181 protein protein human Homo sapiens Human MEDLGENTMVLSTLRSLNNFISQRVEGGSGLDISTSAPGSLQMQYQQSMQLEERAEQIRSKSHLIQVEREKMQMELSHKRARVELERAASTSARNYEREVDRNQELLTRIRQLQEREAGAEEKMQEQLERNRQCQQNLDAASKRLREKEDSLAQAGETINALKGRISELQWSVMDQEMRVKRLESEKQELQEQLDLQHKKCQEANQKIQELQASQEARADHEQQIKDLEQKLSLQEQDAAIVKNMKSELVRLPRLERELKQLREESAHLREMRETNGLLQEELEGLQRKLGRQEKMQETLVGLELENERLLAKLQSWERLDQTMGLSIRTPEDLSRFVVELQQRELALKDKNSAVTSSARGLEKARQQLQEELRQVSGQLLEERKKRETHEALARRLQKRVLLLTKERDGMRAILGSYDSELTPAEYSPQLTRRMREAEDMVQKVHSHSAEMEAQLSQALEELGGQKQRADMLEMELKMLKSQSSSAEQSFLFSREEADTLRLKVEELEGERSRLEEEKRMLEAQLERRALQGDYDQSRTKVLHMSLNPTSVARQRLREDHSQLQAECERLRGLLRAMERGGTVPADLEAAAASLPSSKEVAELKKQVESAELKNQRLKEVFQTKIQEFRKACYTLTGYQIDITTENQYRLTSLYAEHPGDCLIFKATSPSGSKMQLLETEFSHTVGELIEVHLRRQDSIPAFLSSLTLELFSRQTVA DIP protein Q9Y6D9 original sequence version: 56 DIP protein Q9Y6D9 original sequence version: 99 DIP protein Q9Y6D9-1 original sequence version: 135 DIP protein Q9Y6D9 original sequence version: 135 DIP protein Q9Y6D9 original sequence version: 113 DA65529856A37EE3 junb_human Transcription factor jun-B JUNB protein protein human Homo sapiens Human MCTKMEQPFYHDDSYTATGYGRAPGGLSLHDYKLLKPSLAVNLADPYRSLKAPGARGPGPEGGGGGSYFSGQGSDTGASLKLASSELERLIVPNSNGVITTTPTPPGQYFYPRGGGSGGGAGGAGGGVTEEQEGFADGFVKALDDLHKMNHVTPPNVSLGATGGPPAGPGGVYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHPAQLGLGRGASTFKEEPQTVPEARSRDATPPVSPINMEDQERIKVERKRLRNRLAATKCRKRKLERIARLEDKVKTLKAENAGLSSTAGLLREQVAQLKQKVMTHVSNGCQLLLGVKGHAF DIP protein P17275 original sequence version: 151 DIP protein P17275 original sequence version: 118 DIP protein P17275 original sequence version: 143 DF8CD1CD4409C6BE nf2l2_human Nuclear factor erythroid 2-related factor 2 NFE2L2 NRF2 Nuclear factor, erythroid derived 2, like 2 HEBP1 protein protein human Homo sapiens Human MMDLELPPPGLPSQQDMDLIDILWRQDIDLGVSREVFDFSQRRKEYELEKQKKLEKERQEQLQKEQEKAFFAQLQLDEETGEFLPIQPAQHIQSETSGSANYSQVAHIPKSDALYFDDCMQLLAQTFPFVDDNEVSSATFQSLVPDIPGHIESPVFIATNQAQSPETSVAQVAPVDLDGMQQDIEQVWEELLSIPELQCLNIENDKLVETTMVPSPEAKLTEVDNYHFYSSIPSMEKEVGNCSPHFLNAFEDSFSSILSTEDPNQLTVNSLNSDATVNTDFGDEFYSAFIAEPSISNSMPSPATLSHSLSELLNGPIDVSDLSLCKAFNQNHPESTAEFNDSDSGISLNTSPSVASPEHSVESSSYGDTLLGLSDSEVEELDSAPGSVKQNGPKTPVHSSGDMVQPLSPSQGQSTHVHDAQCENTPEKELPVSPGHRKTPFTKDKHSSRLEAHLTRDELRAKALHIPFPVEKIINLPVVDFNEMMSKEQFNEAQLALIRDIRRRGKNKVAAQNCRKRKLENIVELEQDLDHLKDEKEKLLKEKGENDKSLHLLKKQLSTLYLEVFSMLRDEDGKPYSPSEYSLQQTRDGNVFLVPKSKKPDVKKN DIP protein Q16236 original sequence version: 80 DIP protein Q16236 original sequence version: 103 DIP protein Q16236 original sequence version: 148 DIP protein Q16236 original sequence version: 102 DIP protein Q16236-1 original sequence version: 113 99FAFD811B6C1416 nc2b_human Protein Dr1 Down-regulator of transcription 1 TATA-binding protein-associated phosphoprotein Negative cofactor 2-beta DR1 protein protein human Homo sapiens Human MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI 36E7E59F2FD6CAB5 grb2_human Growth factor receptor-bound protein 2 GRB2 ASH Adapter protein GRB2 SH2/SH3 adapter GRB2 Protein Ash protein protein human Homo sapiens Human MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV 83A4B0BA1B248DC4 cdn1b_human Cyclin-dependent kinase inhibitor 1B Cyclin-dependent kinase inhibitor p27 p27Kip1 CDKN1B KIP1 protein protein human Homo sapiens Human MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT DIP protein P46527 original sequence version: 120 DIP protein P46527 original sequence version: 115 DIP protein P46527 original sequence version: 154 DIP protein P46527 original sequence version: 168 DIP protein P46527 original sequence version: 164 DIP protein P46527 original sequence version: 118 1118D58901CDF3FC batf_human Basic leucine zipper transcriptional factor ATF-like SF-HT-activated gene 2 protein BATF B-cell-activating transcription factor protein protein human Homo sapiens Human MPHSSDSSDSSFSRSPPPGKQDSSDDVRRVQRREKNRIAAQKSRQRQTQKADTLHLESEDLEKQNAALRKEIKQLTEELKYFTSVLNSHEPLCSVLAASTPSPPEVVYSAHAFHQPHVSSPRFQP 7FD633C6F1963DF4 7FD633C6F1963DF4 md2l1_human Mitotic spindle assembly checkpoint protein MAD2A MAD2L1 MAD2 Mitotic arrest deficient 2-like protein 1 protein protein human Homo sapiens Human MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLELIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKSQKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEEVRLRSFTTTIHKVNSMVAYKIPVND DIP protein Q13257 original sequence version: 133 DIP protein Q13257 original sequence version: 78 DIP protein Q13257 original sequence version: 105 DIP protein Q13257 original sequence version: 120 DIP protein Q13257 original sequence version: 127 DIP protein Q13257 original sequence version: 116 DIP protein Q13257 original sequence version: 150 DIP protein Q13257 original sequence version: 156 DIP protein Q13257 original sequence version: 134 B8DCBF0043836764 ccna1_human Cyclin-A1 CCNA1 protein protein human Homo sapiens Human METGFPAIMYPGSFIGGWGEEYLSWEGPGLPDFVFQQQPVESEAMHCSNPKSGVVLATVARGPDACQILTRAPLGQDPPQRTVLGLLTANGQYRRTCGQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMAFEDVYEVDTGTLKSDLHFLLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDRFLSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHLLLKVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAFCLANYTVNKHFWPETLAAFTGYSLSEIVPCLSELHKAYLDIPHRPQQAIREKYKASKYLCVSLMEPPAVLLLQ C9C023EEA1CF036D pcna_human Proliferating cell nuclear antigen PCNA Cyclin protein protein human Homo sapiens Human MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSMDSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILKCAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMDLDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVISCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMNEPVQLTFALRYLNFFTKATPLSSTVTLSMSADVPLVVEYKIADMGHLKYYLAPKIEDEEGS DIP protein P12004 original sequence version: 200 DIP protein P12004 original sequence version: 128 DIP protein P12004 original sequence version: 139 DIP protein P12004 original sequence version: 185 DIP protein P12004 original sequence version: 102 DIP protein P12004 original sequence version: 105 DIP protein P12004 original sequence version: 158 E6F08E7EDBC48B00 vav_human Proto-oncogene vav VAV1 VAV protein protein human Homo sapiens Human MELWRQCTHWLIQCRVLPPSHRVTWDGAQVCELAQALRDGVLLCQLLNNLLPHAINLREVNLRPQMSQFLCLKNIRTFLSTCCEKFGLKRSELFEAFDLFDVQDFGKVIYTLSALSWTPIAQNRGIMPFPTEEESVGDEDIYSGLSDQIDDTVEEDEDLYDCVENEEAEGDEIYEDLMRSEPVSMPPKMTEYDKRCCCLREIQQTEEKYTDTLGSIQQHFLKPLQRFLKPQDIEIIFINIEDLLRVHTHFLKEMKEALGTPGAANLYQVFIKYKERFLVYGRYCSQVESASKHLDRVAAAREDVQMKLEECSQRANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHTQEAMEKENLRLALDAMRDLAQCVNEVKRDNETLRQITNFQLSIENLDQSLAHYGRPKIDGELKITSVERRSKMDRYAFLLDKALLICKRRGDSYDLKDFVNLHSFQVRDDSSGDRDNKKWSHMFLLIEDQGAQGYELFFKTRELKKKWMEQFEMAISNIYPENATANGHDFQMFSFEETTSCKACQMLLRGTFYQGYRCHRCRASAHKECLGRVPPCGRHGQDFPGTMKKDKLHRRAQDKKRNELGLPKMEVFQEYYGLPPPPGAIGPFLRLNPGDIVELTKAEAEQNWWEGRNTSTNEIGWFPCNRVKPYVHGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISRPAVGSTKYFGTAKARYDFCARDRSELSLKEGDIIKILNKKGQQGWWRGEIYGRVGWFPANYVEEDYSEYC AC3BC9736FD2F138 nc2a_human Dr1-associated corepressor Dr1-associated protein 1 DRAP1 Negative cofactor 2-alpha protein protein human Homo sapiens Human MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHMDGDKGARRGRKPGSGGRKNGGMGTKSKDKKLSGTDSEQEDESEDTDTDGEEETSQPPPQASHPSAHFQSPPTPFLPFASTLPLPPAPPGPSAPDEEDEEDYDS 6154C43C6B8DC877 mafg_human Transcription factor MafG V-maf musculoaponeurotic fibrosarcoma oncogene homolog G MAFG hMAF protein protein human Homo sapiens Human MTTPNKGNKALKVKREPGENGTSLTDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKAELQQEVEKLASENASMKLELDALRSKYEALQTFARTVARSPVAPARGPLAAGLGPLVPGKVAATSVITIVKSKTDARS E49F1FBA230F8D30 fen1-pcna-1 2 13 unspecified role unspecified role unspecified role unspecified role 3 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D junb-batf-1 2 10 unspecified role unspecified role unspecified role unspecified role 5 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D mad1l1-mad2l1-2 2 4 unspecified role unspecified role unspecified role unspecified role 11 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D mafg-nfe2l2 2 6 unspecified role unspecified role unspecified role unspecified role 16 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D grb2-vav1-3 2 8 unspecified role unspecified role unspecified role unspecified role 14 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D cdkn1b-ccna1-2 2 12 unspecified role unspecified role unspecified role unspecified role 9 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D dr1-drap1 2 15 unspecified role unspecified role unspecified role unspecified role 7 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D junb-batf-2 1 5 unspecified role unspecified role unspecified role unspecified role 10 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D fen1-pcna-2 1 3 unspecified role unspecified role unspecified role unspecified role 13 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D mad1l1-mad2l1-3 1 4 unspecified role unspecified role unspecified role unspecified role 11 unspecified role unspecified role unspecified role unspecified role physical association physical association 1D