MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. Transmembrane mucins Hkr1 and Msb2 are putative osmosensors in the SHO1 branch of yeast HOG pathway. EMBO J. (0261-4189) 2007 imex curation Tatebayashi K., Tanaka K., Yang HY., Yamamoto K., Matsushita Y., Tomida T., Imai M., Saito H. 2009-01-08 Only protein-protein interactions in vitro In vitro pull down pull down predetermined predetermined participant predetermined Tatebayashi K., Tanaka K., Yang HY., Yamamoto K., Matsushita Y., Tomida T., Imai M., Saito H. EMBO J. (0261-4189) 2007 2009-01-08 Only protein-protein interactions imex curation msb2_yeast Signaling mucin MSB2 MSB2 Multicopy suppressor of bud emergence 2 Osmosensor MSB2 YGR014W protein protein yeast Saccharomyces cerevisiae Baker's yeast MQFPFACLLSTLVISGSLARASPFDFIFGNGTQQAQSQSESQGQVSFTNEASQDSSTTSLVTAYSQGVHSHQSATIVSATISSLPSTWYDASSTSQTSVSYASQESDYAVNQNSWSASTNQLPSTSTTSYYAPTFSTSADFAASSVNAASDVSTASVPIDTSANSIPFTTTSNIETTTSAPLTSDTPLISTSTMSAADNVFSSANPISASLTTTDSSESFDQTSTAGAIPVQSSADFSSSSEILVQSSADFSSPSSPTTTDISLSAAPLQTSESSSFTTASAALPVSSTDVDGSSASPVVSMSAAGQIASSSSTDNPTMSETFSLTSTEVDGSDVSSTVSALLSAPFLQTSTSNSFSIVSPSVSFVPSQSSSDVASSSTANVVSSSFSDIPPQTSTSGSVVSVAQSASALAFQSSTEVYGASASSTMSSLLSTTSLQSTTLDSSSLASSSASSSDLTDYGVSSTASIPLLSASEQASTSSSFSVVSPSVSFVPSQSSSDVASTSAPSVVSSSFSYTSLQAGGSSMTNPSSSTIVYSSSTGSSEESAASTASATLSGSSSTYMAGNLQSQPPSTSSLLSESQATSTSAVLASSSVSTTSPYTTAGGASTEASSLISSTSAETSQVSYSQSTTALQTSSFASSSTTEGSETSSQGFSTSSVLVQMPSSISSEFSPSQTTTQMNSASSSSQYTISSTGILSQVSDTSVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTPVSYTTSSSSVSQVSDTSVPSTSSRSSVSQVSDTPVPSTSSRSSVSQTSSSLQPTTTSSQRFTISTHGALSESSSVSQQASEITSSINATASEYHSIQTTAATQSTTLSFTDANSSSASAPLEVATSTPTPSSKASSLLLTPSTSSLSQVATNTNVQTSLTTESTTVLEPSTTNSSSTFSLVTSSDNNWWIPTELITQAPEAASTASSTVGGTQTMTLPHAIAAATQVPEPEGYTLITIGFKKALNYEFVVSEPKSSAQIFGYLPEALNTPFKNVFTNITVLQIVPLQDDSLNYLVSVAEVYFPTAEIEELSNLITNSSSAFYTDGMGTAKSMAAMVDSSIPLTGLLHDSNSNSGGSSDGSSSSNSNSGSSGSGSNSNSGVSSSSGNSYQDAGTLEYSSKSNSNVSTSSKSKKKIIGLVIGVVVGGCLYILFMIFAFKYIIRRRIQSQEIIKNPEISSISSSEFGGEKNYNNEKRMSVQESITQSMRIQNWMDDSYYGHGLTNNDSTPTRHNTSSSIPKISRPIASQNSLGWNEV 67D5D984D5CA4A6D hkr1_yeast Signaling mucin HKR1 YDR420W HKR1 Hansenula MRAKII killer toxin-resistant protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MVSLKIKKILLLVSLLNAIEAYSNDTIYSTSYNNGIESTPSYSTSAISSTGSSNKENAITSSSETTTMAGQYGESGSTTIMDEQETGTSSQYISVTTTTQTSDTMSSVKKSTEIATPSSSIVPTPLQSYSDESQISQTLSHNPKSVAESDSDTTSSESSSSVIISTSDSSAVPREISPIITTDSQISKEEGTLAQTSSISETTRIAQMVTRVSQISSITAASTIDGFSSESTQTDFSNTVSFENSVEEEYAMSKSQLSESYSSSSTVYSGGESTADKTSSSPITSFSSSYSQTTSTETSESSRVAVGVSRPSSITQTTSIDSFSMSEVELSTYYDLSAGNYPDQELIVDRPATSSTAETSSEASQGVSRESNTFAVSSISTTNFIVSSASDTVVSTSSTNTVPYSSVHSTFVHATSSSTYISSSLYSSPSLSASVSSHFGVAPFPSAYISFSSVPVAVSSTYTSSPSASVVVPSAYASSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPVAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSVPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSAPAAISSTYTSSPSAPVAVSSTYTSSPSALVVLSSTSTSSPYDIVYSPSTFAAISSGYTPSPSASVAMSSTSSSSPYDIVYSLSSSASRSSIATYEFSPSPSTSLPTSSTYTYFSSAYAFEFSSERYSTTSTIAPTQIHSTLSRITDFLLQTSMAIQSIVSQQISTSSTLNDEIHSSALSVFNPSASNLVETSLIISSTQASITSPKNSAKISSLQSQLSSSTKNPYDTANKNTETSGRSTVVSNFLYTSSAAKPDNEKFSATPTEITTISSSSHAYSLSIPSSHNSVTGLSHNFVDSSKSATSFGYSSSSISSIKLSKETIPASKSVSNTQERITSFTSTLRANSQSEKSEGRNSVGSLQSSHISSNPSLSTNTKVDSKSLSRKVSKTMGENGEETGLTTTKTQYKSSSETSGSYSRSFTKISIGPATTAVQTQASTNSVFTAPALSTYPTTPYPSPNSYAWLPTAIIVESSETGPTTASFNPSITGSLPNAIEPAVAVSEPINHTLITIGFTAALNYVFLVQNPLSSAQIFNFLPLVLKYPFSNTSSELDNSIGELSTFILSYRSGSSTTTLSPKSISSLSVVKKKKNQQKKNATKSTEDLHPPQVDTSSIAVKKIVPMVDSSKAYIVSVAEVYFPTEAVTYLQQLILDENSTLYSNPQTPLRSLAGLIDSGIPLGGLTLYGSGDGGYVPSLTSSSVLDSSKGNSQNIDGTYKYGALDDFINSFTDSASAGKYAVKIIIFLIVLTIGVLLWLFVAFFAFRHRNILLKRHPRNCIGKSLNNERELESTELSRSSSGNQVYNEKPPESENESVYSAVDDHYIVTGENTVYNTIHRLHYTINDDGDLLYRDAIPLDFDQTNGDDGSGIDSIVRDCVYDKNQDATEAFLNDEESISGILDVDENGDIRLYDSYSDNEESNSFHLPDEVIENYNKNHLCETKLHGLGTESCTTDDPDTGNQITNEFSTGSQTCLPSTAYTTPLHTNSIKLHTLRYTESSLPKPNQTLFSNLEDLEIEDIDDNGSVSDVHIEELDALDEELYKRMSKVIKQQNHQTTKI 0FF726990C7CDC51 sho1_yeast High osmolarity signaling protein SHO1 YER118C SHO1 SSU81 Osmosensor SHO1 Suppressor of SUA8-1 mutation Synthetic high osmolarity-sensitive protein 1 protein protein yeast Saccharomyces cerevisiae Baker's yeast MSISSKIRPTPRKPSRMATDHSFKMKKFYADPFAISSISLAIVSWVIAIGGSISSASTNESFPRFTWWGIVYQFLIICSLMLFYCFDLVDHYRIFITTSIAVAFVYNTNSATNLVYADGPKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPYQNNVYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFENTQPNTSEAVNLHLNTLQQRINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQNEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR E467A4D50AA3EDB6 E467A4D50AA3EDB6 ssu81-hkr1 1 HKR1 3 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed cell lysate cell lysate ha tagged ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined SHO1 4 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P40073:p.Tyr106His mutation decreasing interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Y H Tue Jul 12 10:11:01 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation decreasing' Wed May 02 15:58:34 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr106his' Tue Jun 30 20:20:30 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr106His' range MINT-5225277: original sequence: 106-106 : ITTSIAVAFVYNTNSATNLV gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined P40073:p.Thr108Ile mutation decreasing interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain T I Tue Jul 12 10:11:07 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation decreasing' Wed May 02 19:59:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr108ile' Tue Jun 30 19:47:00 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr108Ile' range MINT-5225280: original sequence: 108-108 : TSIAVAFVYNTNSATNLVYA physical association physical association f6e mint ssu81-msb2 1 HKR1 MSB2 2 anti tag western anti tag western blot anti tag western predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed cell lysate cell lysate ha tagged ha tag ha tag YPYDVPDYA epitope tag YPYDVPDYA epitope tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined SHO1 4 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role bait bait purified purified P40073:p.Tyr106His mutation decreasing interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain Y H Tue Jul 12 10:52:55 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation decreasing' Wed May 02 16:59:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'tyr106his' Tue Jun 30 16:13:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Tyr106His' range MINT-5225284: original sequence: 106-106 : ITTSIAVAFVYNTNSATNLV P40073:p.Thr108Ile mutation decreasing interaction mutation decreasing mutation decreasing interaction hotspot hotspot mutation decreasing mutation analysis mutation analysis certain certain sequence position certain certain certain sequence position certain T I Tue Jul 12 10:13:02 BST 2016 This feature has been corrected as a result of our quality control procedures. The original label was 'mutation decreasing' Wed May 02 16:35:45 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'thr108ile' Tue Jun 30 18:08:15 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Thr108Ile' range MINT-5225287: original sequence: 108-108 : TSIAVAFVYNTNSATNLVYA gst tagged gst tag glutathione s tranferase tag glutathione S-tranferase tag glutathione S-tranferase tag gst tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined physical association physical association f6e mint