IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2. Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2. Arthritis Rheum. (0004-3591) 2004 imex curation Buisson-Legendre N., Smith S., March L., Jackson C. The coimmunoprecipitation was carried out on synovial fluid from patients with osteoarthritis. nathalie@med.usyd.edu.au 12-Oct-2007: Contacted by JYOTI. Only protein-protein interactions human-synovial_fluid Homo sapiens synovial fluid synovial_fluid Synovial fluid anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Buisson-Legendre N., Smith S., March L., Jackson C. The coimmunoprecipitation was carried out on synovial fluid from patients with osteoarthritis. nathalie@med.usyd.edu.au Accepted 2007-OCT-24 by JYOTI. Arthritis Rheum. (0004-3591) 2004 Only protein-protein interactions imex curation Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2. Elevation of activated protein C in synovial joints in rheumatoid arthritis and its correlation with matrix metalloproteinase 2. Arthritis Rheum. (0004-3591) 2004 imex curation Buisson-Legendre N., Smith S., March L., Jackson C. The coimmunoprecipitation was carried out on synovial fluid from patients with osteoarthritis. nathalie@med.usyd.edu.au 12-Oct-2007: Contacted by JYOTI. Only protein-protein interactions human-rheu_arth_syn_fluid Homo sapiens rheumatoid arthritic synovial fluid synovial_fluid_ra Synovial fluid from rheumotoid arthritis patient anti bait coip anti bait coimmunoprecipitation anti bait coip western blot western blot Immuno blot Immuno blot Buisson-Legendre N., Smith S., March L., Jackson C. The coimmunoprecipitation was carried out on synovial fluid from patients with rheumatoid arthritis. nathalie@med.usyd.edu.au Accepted 2007-OCT-24 by JYOTI. 12-Oct-2007: Contacted by JYOTI. Arthritis Rheum. (0004-3591) 2004 Only protein-protein interactions imex curation proc_human Vitamin K-dependent protein C PROC Autoprothrombin IIA Anticoagulant protein C Blood coagulation factor XIV protein protein human Homo sapiens Human MWQLTSLLLFVATWGISGTPAPLDSVFSSSERAHQVLRIRKRANSFLEELRHSSLERECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCLVLPLEHPCASLCCGHGTCIDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRRWEKWELDLDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQKSWAP 3531B0AE5345B39A mmp15_human Matrix metalloproteinase-15 MMP15 Membrane-type matrix metalloproteinase 2 Membrane-type-2 matrix metalloproteinase SMCP-2 protein protein human Homo sapiens Human MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV FE875EC0674B297F proc-mmp15 1 3 unspecified role unspecified role bait bait 4 unspecified role unspecified role prey prey physical association physical association 3 D Western blot analysis demonstrated the presence of latent and active MMP-2 in the immunoprecipitate from both RA and OA synovial fluid Both active and latent MMP-2 were coimmunoprecipitated with PC/APC. proc-mmp15-1 2 4 unspecified role unspecified role prey prey 3 unspecified role unspecified role bait bait physical association physical association 3 D Western blot analysis demonstrated the presence of latent and active MMP-2 in the immunoprecipitate from both RA and OA synovial fluid Both active and latent MMP-2 were coimmunoprecipitated with PC/APC.