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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>IntAct</shortLabel>
        <fullName>European Bioinformatics Institute</fullName>
        <alias type="synonym" typeAc="MI:1041">IntAct</alias>
        <alias type="synonym" typeAc="MI:1041">intact</alias>
      </names>
      <bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="14681455" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
      </bibref>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0469" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-10" refType="identity" refTypeAc="MI:0356"/>
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        <secondaryRef db="pubmed" dbAc="MI:0446" id="22121220" refType="method reference" refTypeAc="MI:0357"/>
        <secondaryRef db="pubmed" dbAc="MI:0446" id="19850723" refType="method reference" refTypeAc="MI:0357"/>
      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/</attribute>
        <attribute name="search-url" nameAc="MI:0615">http://www.ebi.ac.uk/intact/query/${ac}</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">EBI-[0-9]+|IA:[0-9]+</attribute>
        <attribute name="definition">INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions.</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact</attribute>
        <attribute name="postaladdress">European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom</attribute>
        <attribute name="url" nameAc="MI:0614">http://www.ebi.ac.uk/intact/</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Phosphorylation of the DNA polymerase alpha-primase B subunit is dependent on its association with the p180 polypeptide.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="8621497" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1993029" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="imex" dbAc="MI:0670" id="IM-20079" refType="imex-primary" refTypeAc="MI:0662"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Phosphorylation of the DNA polymerase alpha-primase B subunit is dependent on its association with the p180 polypeptide.</attribute>
            <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
            <attribute name="publication year" nameAc="MI:0886">1996</attribute>
            <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
            <attribute name="author-list" nameAc="MI:0636">Ferrari M., Lucchini G., Plevani P., Foiani M.</attribute>
            <attribute name="exp-modification" nameAc="MI:0627">Yeast strain CG378 was synchronized by alpha-factor treatment and the degree of synchrony was measured by microscopic analysis of cell budding</attribute>
            <attribute name="antibodies" nameAc="MI:0671">Anti-primase complex</attribute>
            <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
            <attribute name="imex curation" nameAc="MI:0959"/>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="pubmed" dbAc="MI:0446" id="8621497" refType="primary-reference" refTypeAc="MI:0358"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-20079" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="4932">
            <names>
              <shortLabel>yeasx</shortLabel>
              <fullName>Saccharomyces cerevisiae (Baker's yeast)</fullName>
              <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>coip</shortLabel>
            <fullName>coimmunoprecipitation</fullName>
            <alias type="go synonym" typeAc="MI:0303">co-immunoprecipitation</alias>
            <alias type="go synonym" typeAc="MI:0303">CoIp</alias>
            <alias type="go synonym" typeAc="MI:0303">immunoprecipitation</alias>
            <alias type="go synonym" typeAc="MI:0303">Co-IP</alias>
            <alias type="synonym" typeAc="MI:1041">co-immunoprecipitation</alias>
            <alias type="synonym" typeAc="MI:1041">CoIp</alias>
            <alias type="synonym" typeAc="MI:1041">immunoprecipitation</alias>
            <alias type="synonym" typeAc="MI:1041">Co-IP</alias>
            <alias type="synonym" typeAc="MI:1041">coip</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0019" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-98" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="7708014" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>western blot</shortLabel>
            <fullName>western blot</fullName>
            <alias type="go synonym" typeAc="MI:0303">Immuno blot</alias>
            <alias type="synonym" typeAc="MI:1041">Immuno blot</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0113" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-973" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Ferrari M., Lucchini G., Plevani P., Foiani M.</attribute>
          <attribute name="exp-modification" nameAc="MI:0627">Yeast strain CG378 was synchronized by alpha-factor treatment and the degree of synchrony was measured by microscopic analysis of cell budding</attribute>
          <attribute name="accepted">Annotation to indicate that this entry has been checked and accepted by a senior curator.</attribute>
          <attribute name="antibodies" nameAc="MI:0671">Anti-primase complex</attribute>
          <attribute name="journal" nameAc="MI:0885">J. Biol. Chem. (0021-9258)</attribute>
          <attribute name="publication year" nameAc="MI:0886">1996</attribute>
          <attribute name="full coverage" nameAc="MI:0957">Only protein-protein interactions</attribute>
          <attribute name="imex curation" nameAc="MI:0959"/>
          <attribute name="curation depth" nameAc="MI:0955">imex curation</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>pri2_yeast</shortLabel>
          <fullName>DNA primase large subunit</fullName>
          <alias type="gene name" typeAc="MI:0301">PRI2</alias>
          <alias type="locus name" typeAc="MI:0305">YKL045W</alias>
          <alias type="orf name" typeAc="MI:0306">YKL258</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA primase 58 kDa subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase alpha:primase complex p58 subunit</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P20457" version="SP_63" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblfungi" id="YKL045W" version="SP_171" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VXP2" version="SP_90" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13867" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-113501" version="SP_171"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68952" version="SP_171"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68962" version="SP_171"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69091" version="SP_171"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69166" version="SP_171"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69183" version="SP_171"/>
          <secondaryRef db="ensemblfungi" id="YKL045W" version="SP_171" refType="gene"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0051539" version="SP_171"/>
          <secondaryRef db="ensemblfungi" id="YKL045W_mRNA" version="SP_171" refType="transcript"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007238" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_171"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016558" version="SP_171"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DTV" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005658" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006260" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006269" version="SP_171"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006270" version="SP_171"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_171"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6DU0" version="SP_171"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_012879.1"/>
          <secondaryRef db="sgd" dbAc="MI:0484" id="S000001528"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P20457"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-2535N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="559292">
          <names>
            <shortLabel>yeast</shortLabel>
            <fullName>Saccharomyces cerevisiae</fullName>
            <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
          </names>
        </organism>
        <sequence>MFRQSKRRIASRKNFSSYDDIVKSELDVGNTNAANQIILSSSSSEEEKKLYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRNKSIKEIETIIKPQFQKLLPFNTESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQFQLNLNEEHQRKQYFQQEKFIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMKLTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSRQLQKKQQKLEKEKLFNNGNH</sequence>
        <attributeList>
          <attribute name="crc64">2DA521AA104D3D16</attribute>
          <attribute name="crc64">2DA521AA104D3D16</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>pri1_yeast</shortLabel>
          <fullName>DNA primase small subunit</fullName>
          <alias type="gene name" typeAc="MI:0301">PRI1</alias>
          <alias type="locus name" typeAc="MI:0305">YIR008C</alias>
          <alias type="orf name" typeAc="MI:0306">YIB8C</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA primase 48 kDa subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase alpha:primase complex p48 subunit</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P10363" version="SP_71" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="ensemblfungi" id="YIR008C" version="SP_184" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VVT8" version="SP_102" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-13863" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_012273.1"/>
          <secondaryRef db="sgd" dbAc="MI:0484" id="S000001447"/>
          <secondaryRef db="ensemblfungi" id="YIR008C" version="SP_184" refType="gene"/>
          <secondaryRef db="ensemblfungi" id="YIR008C_mRNA" version="SP_184" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003896" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005524" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005658" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006260" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006269" version="SP_184"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0043596" version="SP_184"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002755" version="SP_184"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR014052" version="SP_184"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LIM" version="SP_184"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4MM2" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-113501" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68952" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68962" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69091" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69166" version="SP_184"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69183" version="SP_184"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P10363"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-2534N"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="559292">
          <names>
            <shortLabel>yeast</shortLabel>
            <fullName>Saccharomyces cerevisiae</fullName>
            <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
          </names>
        </organism>
        <sequence>MTNSVKTNGPSSSDMEYYYKSLYPFKHIFNWLNHSPKPSRDMINREFAMAFRSGAYKRYNSFNSVQDFKAQIEKANPDRFEIGAIYNKPPRERDTLLKSELKALEKELVFDIDMDDYDAFRTCCSGAQVCSKCWKFISLAMKITNTALREDFGYKDFIWVFSGRRGAHCWVSDKRARALTDVQRRNVLDYVNVIRDRNTDKRLALKRPYHPHLARSLEQLKPFFVSIMLEEQNPWEDDQHAIQTLLPALYDKQLIDSLKKYWLDNPRRSSKEKWNDIDQIATSLFKGPKQDSHIIKLRECKEDLVLMTLYPKLDVEVTKQTIHLLKAPFCIHPATGNVCVPIDESFAPEKAPKLIDLQTEMEKNNDVSLTALQPFINQFQAYVSSLLKNELGSVKREREDDDEPASLDF</sequence>
        <attributeList>
          <attribute name="crc64">C4B1C82257AA86F2</attribute>
          <attribute name="crc64">C4B1C82257AA86F2</attribute>
        </attributeList>
      </interactor>
      <interactor id="4">
        <names>
          <shortLabel>dpoa_yeast</shortLabel>
          <fullName>DNA polymerase alpha catalytic subunit A</fullName>
          <alias type="gene name" typeAc="MI:0301">POL1</alias>
          <alias type="gene name synonym" typeAc="MI:0302">CDC17</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase alpha:primase complex p180 subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase I subunit A</alias>
          <alias type="orf name" typeAc="MI:0306">N2181</alias>
          <alias type="locus name" typeAc="MI:0305">YNL102W</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P13382" version="SP_78" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6W177" version="SP_113" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblfungi" id="YNL102W" version="SP_208" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6128" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="sgd" dbAc="MI:0484" id="S000005046"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_014297.3"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-2526N"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P13382"/>
          <secondaryRef db="ensemblfungi" id="YNL102W" version="SP_208" refType="gene"/>
          <secondaryRef db="ensemblfungi" id="YNL102W_mRNA" version="SP_208" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0000731" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003682" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003688" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003697" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003887" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005657" version="SP_208"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006278" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006279" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006302" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0017076" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0019103" version="SP_208"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0046872" version="SP_208"/>
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          <secondaryRef db="go" dbAc="MI:0448" id="GO:1902975" version="SP_208"/>
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          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006134" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR006172" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR012337" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR015088" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR017964" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024647" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036397" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR038256" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR042087" version="SP_208"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043502" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FLO" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3OIQ" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4B08" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4C93" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FVM" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FXD" version="SP_208"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4FYD" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-113501" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68952" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68962" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69091" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69166" version="SP_208"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69183" version="SP_208"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="559292">
          <names>
            <shortLabel>yeast</shortLabel>
            <fullName>Saccharomyces cerevisiae</fullName>
            <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
          </names>
        </organism>
        <sequence>MSSKSEKLEKLRKLQAARNGTSIDDYEGDESDGDRIYDEIDEKEYRARKRQELLHDDFVVDDDGVGYVDRGVEEDWREVDNSSSDEDTGNLASKDSKRKKNIKREKDHQITDMLRTQHSKSTLLAHAKKSQKKSIPIDNFDDILGEFESGEVEKPNILLPSKLRENLNSSPTSEFKSSIKRVNGNDESSHDAGISKKVKIDPDSSTDKYLEIESSPLKLQSRKLRYANDVQDLLDDVENSPVVATKRQNVLQDTLLANPPSAQSLADEEDDEDSDEDIILKRRTMRSVTTTRRVNIDSRSNPSTSPFVTAPGTPIGIKGLTPSKSLQSNTDVATLAVNVKKEDVVDPETDTFQMFWLDYCEVNNTLILFGKVKLKDDNCVSAMVQINGLCRELFFLPREGKTPTDIHEEIIPLLMDKYGLDNIRAKPQKMKYSFELPDIPSESDYLKVLLPYQTPKSSRDTIPSDLSSDTFYHVFGGNSNIFESFVIQNRIMGPCWLDIKGADFNSIRNASHCAVEVSVDKPQNITPTTTKTMPNLRCLSLSIQTLMNPKENKQEIVSITLSAYRNISLDSPIPENIKPDDLCTLVRPPQSTSFPLGLAALAKQKLPGRVRLFNNEKAMLSCFCAMLKVEDPDVIIGHRLQNVYLDVLAHRMHDLNIPTFSSIGRRLRRTWPEKFGRGNSNMNHFFISDICSGRLICDIANEMGQSLTPKCQSWDLSEMYQVTCEKEHKPLDIDYQNPQYQNDVNSMTMALQENITNCMISAEVSYRIQLLTLTKQLTNLAGNAWAQTLGGTRAGRNEYILLHEFSRNGFIVPDKEGNRSRAQKQRQNEENADAPVNSKKAKYQGGLVFEPEKGLHKNYVLVMDFNSLYPSIIQEFNICFTTVDRNKEDIDELPSVPPSEVDQGVLPRLLANLVDRRREVKKVMKTETDPHKRVQCDIRQQALKLTANSMYGCLGYVNSRFYAKPLAMLVTNKGREILMNTRQLAESMNLLVVYGDTDSVMIDTGCDNYADAIKIGLGFKRLVNERYRLLEIDIDNVFKKLLLHAKKKYAALTVNLDKNGNGTTVLEVKGLDMKRREFCPLSRDVSIHVLNTILSDKDPEEALQEVYDYLEDIRIKVETNNIRIDKYKINMKLSKDPKAYPGGKNMPAVQVALRMRKAGRVVKAGSVITFVITKQDEIDNAADTPALSVAERAHALNEVMIKSNNLIPDPQYYLEKQIFAPVERLLERIDSFNVVRLSEALGLDSKKYFRREGGNNNGEDINNLQPLETTITDVERFKDTVTLELSCPSCDKRFPFGGIVSSNYYRVSYNGLQCKHCEQLFTPLQLTSQIEHSIRAHISLYYAGWLQCDDSTCGIVTRQVSVFGKRCLNDGCTGVMRYKYSDKQLYNQLLYFDSLFDCEKNKKQELKPIYLPDDLDYPKEQLTESSIKALTEQNRELMETGRSVVQKYLNDCGRRYVDMTSIFDFMLN</sequence>
        <attributeList>
          <attribute name="crc64">50C9032DBE95B5AE</attribute>
          <attribute name="crc64">50C9032DBE95B5AE</attribute>
        </attributeList>
      </interactor>
      <interactor id="5">
        <names>
          <shortLabel>dpoa2_yeast</shortLabel>
          <fullName>DNA polymerase alpha subunit B</fullName>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase I subunit B</alias>
          <alias type="gene name" typeAc="MI:0301">POL12</alias>
          <alias type="locus name" typeAc="MI:0305">YBL035C</alias>
          <alias type="orf name" typeAc="MI:0306">YBL0414</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase alpha:primase complex p86 subunit</alias>
          <alias type="gene name synonym" typeAc="MI:0302">DNA polymerase-primase complex p74 subunit</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P38121" version="SP_56" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="D6VPW4" version="SP_84" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="ensemblfungi" id="YBL035C" version="SP_163" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6111" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="NP_009518.1"/>
          <secondaryRef db="sgd" dbAc="MI:0484" id="S000000131"/>
          <secondaryRef db="dip" dbAc="MI:0465" id="DIP-2536N"/>
          <secondaryRef db="mint" dbAc="MI:0471" id="P38121"/>
          <secondaryRef db="ensemblfungi" id="YBL035C" version="SP_163" refType="gene"/>
          <secondaryRef db="ensemblfungi" id="YBL035C_mRNA" version="SP_163" refType="transcript"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0003677" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005634" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005635" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005658" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006270" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006273" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0016233" version="SP_163"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0071897" version="SP_163"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR007185" version="SP_163"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR013627" version="SP_163"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR016722" version="SP_163"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="3FLO" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-113501" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68952" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-68962" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69091" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69166" version="SP_163"/>
          <secondaryRef db="reactome" dbAc="MI:0467" id="R-SCE-69183" version="SP_163"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="559292">
          <names>
            <shortLabel>yeast</shortLabel>
            <fullName>Saccharomyces cerevisiae</fullName>
            <alias type="synonym" typeAc="MI:1041">Baker's yeast</alias>
          </names>
        </organism>
        <sequence>MSGSIDVITHFGPDADKPEIITALENLTKLHALSVEDLYIKWEQFSNQRRQTHTDLTSKNIDEFKQFLQLQMEKRANQISSSSKVNTSTKKPVIKKSLNSSPLFGLSIPKTPTLKKRKLHGPFSLSDSKQTYNVGSEAETNEKGNSSLKLEFTPGMAEDAVGDSAPLSHAKSSDAKTPGSSTFQTPTTNTPTTSRQNVPAGEILDSLNPENIEISSGNPNVGLLSTEEPSYNQVKVEPFYDAKKYKFRTMRQNLQEASDVLDDQIESFTKIIQNHYKLSPNDFADPTIQSQSEIYAVGRIVPDSPTYDKFLNPESLSLETSRMGGVGRRVRLDLSQVNELSFFLGQIVAFKGKNANGDYFTVNSILPLPYPNSPVSTSQELQEFQANLEGSSLKVIVTCGPYFANDNFSLELLQEFIDSINNEVKPHVLIMFGPFIDITHPLIASGKLPNFPQFKTQPKTLDELFLKLFTPILKTISPHIQTVLIPSTKDAISNHAAYPQASLIRKALQLPKRNFKCMANPSSFQINEIYFGCSNVDTFKDLKEVIKGGTTSSRYRLDRVSEHILQQRRYYPIFPGSIRTRIKPKDVSTKKETNDMESKEEKVYEHISGADLDVSYLGLTEFVGGFSPDIMIIPSELQHFARVVQNVVVINPGRFIRATGNRGSYAQITVQCPDLEDGKLTLVEGEEPVYLHNVWKRARVDLIAS</sequence>
        <attributeList>
          <attribute name="crc64">F9F06D12F6979637</attribute>
          <attribute name="crc64">F9F06D12F6979637</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="6" imexId="IM-20079-1">
        <names>
          <shortLabel>dpoa-dpoa2-1</shortLabel>
        </names>
        <xref>
          <primaryRef db="intact" dbAc="MI:0469" id="EBI-849030" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0005658" refType="component" refTypeAc="MI:0354"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0007049" refType="process" refTypeAc="MI:0359"/>
          <secondaryRef db="imex" dbAc="MI:0670" id="IM-20079-1" refType="imex-primary" refTypeAc="MI:0662"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="7">
            <interactorRef>3</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="8">
            <interactorRef>2</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="9">
            <interactorRef>4</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
          </participant>
          <participant id="10">
            <interactorRef>5</interactorRef>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1383079" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <featureList>
              <feature id="11">
                <names>
                  <shortLabel>region</shortLabel>
                  <fullName>(potential)</fullName>
                </names>
                <xref>
                  <primaryRef db="intact" dbAc="MI:0469" id="EBI-849035" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>phosres</shortLabel>
                    <fullName>phosphorylated residue</fullName>
                    <alias type="synonym" typeAc="MI:1041">PhosRes</alias>
                    <alias type="synonym" typeAc="MI:1041">Phospho</alias>
                    <alias type="synonym" typeAc="MI:1041">Phosphorylation</alias>
                    <alias type="synonym" typeAc="MI:1041">Phosphorylation (O of Serine, Threonine, Tyrosine and Aspartate, N epsilon of Lysine)</alias>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0170" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="psi-mod" dbAc="MI:0897" id="MOD:00696" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-6410650" refType="secondary-ac" refTypeAc="MI:0360"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456700" refType="identity" refTypeAc="MI:0356"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>association</shortLabel>
            <fullName>association</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0914" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1813191" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="remark-internal">Ab is to the entire complex, so impossible to tell which protein(s) is actually the bait.</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>