MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Structure and oligomeric state of human transcription factor TFIIE. Structure and oligomeric state of human transcription factor TFIIE. EMBO Rep. (1469-221X) 2006 imex curation Jawhari A., Uhring M., De Carlo S., Crucifix C., Tocchini-Valentini G., Moras D., Schultz P., Poterszman A. 2009-01-08 Only protein-protein interactions in vitro In vitro electron microscopy electron microscopy Electron crystallography Electron cryomicroscopy Electron crystallography Electron cryomicroscopy predetermined predetermined participant predetermined Jawhari A., Uhring M., De Carlo S., Crucifix C., Tocchini-Valentini G., Moras D., Schultz P., Poterszman A. EMBO Rep. (1469-221X) 2006 2009-01-08 Only protein-protein interactions imex curation Structure and oligomeric state of human transcription factor TFIIE. Structure and oligomeric state of human transcription factor TFIIE. EMBO Rep. (1469-221X) 2006 imex curation Jawhari A., Uhring M., De Carlo S., Crucifix C., Tocchini-Valentini G., Moras D., Schultz P., Poterszman A. 2009-01-08 Only protein-protein interactions in vitro In vitro crosslink cross-linking study crosslink predetermined predetermined participant predetermined Jawhari A., Uhring M., De Carlo S., Crucifix C., Tocchini-Valentini G., Moras D., Schultz P., Poterszman A. EMBO Rep. (1469-221X) 2006 2009-01-08 Only protein-protein interactions imex curation t2ea_human General transcription factor IIE subunit 1 GTF2E1 TF2E1 General transcription factor IIE 56 kDa subunit Transcription initiation factor IIE subunit alpha protein protein human Homo sapiens Human MADPDVLTEVPAALKRLAKYVIRGFYGIEHALALDILIRNSCVKEEDMLELLKFDRKQLRSVLNNLKGDKFIKCRMRVETAADGKTTRHNYYFINYRTLVNVVKYKLDHMRRRIETDERDSTNRASFKCPVCSSTFTDLEANQLFDPMTGTFRCTFCHTEVEEDESAMPKKDARTLLARFNEQIEPIYALLRETEDVNLAYEILEPEPTEIPALKQSKDHAATTAGAASLAGGHHREAWATKGPSYEDLYTQNVVINMDDQEDLHRASLEGKSAKERPIWLRESTVQGAYGSEDMKEGGIDMDAFQEREEGHAGPDDNEEVMRALLIHEKKTSSAMAGSVGAAAPVTAANGSDSESETSESDDDSPPRPAAVAVHKREEDEEEDDEFEEVADDPIVMVAGRPFSYSEVSQRPELVAQMTPEEKEAYIAMGQRMFEDLFE DIP protein P29083 original sequence version: 70 DIP protein P29083 original sequence version: 160 9234FFE3F150340B t2eb_human Transcription initiation factor IIE subunit beta GTF2E2 TF2E2 General transcription factor IIE subunit 2 protein protein human Homo sapiens Human MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSSKKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLDEILDETQHLDIGLKQKQWLMTEALVNNPKIEVIDGKYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKALGDQILFVNRPDKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKTHNEHLAGVLKDYSDITSSK DIP protein P29084 original sequence version: 171 DIP protein P29084 original sequence version: 162 20F6BDFF2E06E5E7 gtf2e1-gtf2e2 1 3 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Stoichiometry: 1.0 4 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Stoichiometry: 1.0 direct interaction direct interaction F2 EMBO-Reports The analysis of 4,480 images of large particles resulted in class averages that clearly showed a two-fold symmetry axis consistent with a2/b2 tetramers homomint mint gtf2e1-gtf2e2-1 2 3 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Stoichiometry: 1.0 4 predetermined predetermined participant predetermined predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component purified purified Stoichiometry: 1.0 direct interaction direct interaction F3A EMBO-Reports When TFIIE (Fig 3A, lane 1) was chemically crosslinked with 0.02% glutaraldehyde, a single polypeptide with an estimated molecular mass of 90 kDa corresponding to the a/b heterodimer was generated, whereas no band of higher molecular mass was detected (Fig 3A, lane 2). homomint mint