MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Exp. Cell Res. (0014-4827) 2005 Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no Exp. Cell Res. (0014-4827) 2005 The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Exp. Cell Res. (0014-4827) 2005 Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no yeast Saccharomyces cerevisiae Baker's yeast two hybrid pooling two hybrid pooling approach two hybrid pooling nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no Exp. Cell Res. (0014-4827) 2005 The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Exp. Cell Res. (0014-4827) 2005 Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 anti bait coip anti bait coimmunoprecipitation anti bait coip predetermined predetermined participant predetermined Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no Exp. Cell Res. (0014-4827) 2005 The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Exp. Cell Res. (0014-4827) 2005 Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no chlae-cos_7 Cercopithecus aethiops simian cells transformed with SV40 Grivet cos_7 cercopithecus aethiops, by transformation with SV40 fluorescence imaging fluorescence microscopy fluorescence imaging immunostaining immunostaining Nunes SM., Ferralli J., Choi K., Brown-Luedi M., Minet AD., Chiquet-Ehrismann R. no Exp. Cell Res. (0014-4827) 2005 mbd1_mouse Methyl-CpG-binding domain protein 1 Mbd1 Methyl-CpG-binding protein MBD1 protein protein mouse Mus musculus Mouse MAESWQDCPALGPGWKRRESFRKSGASFGRSDIYYQSPTGEKIRSKVELTRYLGPACDLTLFDFRQGTLCHPIPKTHPLAVPSKKKKKPSKPAKTKKQQVGLQRSEVRIETPQGEYKAPTATALASLSVSASASSSASASASASSHAPVCCENCGIHFSWDGVKRQRLKTLCKDCRAQRIAFNREQRMFKRVGCGDCAACLVKEDCGVCSTCRLQLPSDVASGLYCKCERRRCLRIMEKSRGCGVCRGCQTQEDCGHCCICLRSPRPGLKRQWRCLQRRCFWGKRDSSKRGSKVASQRHSQAPPLPPHPASQYTEPTELHISDIAPTSPAEFIYYCVDEDEDELQPYTNQRQNRKCGACAACLRRMDCGRCDFCCDKPKFGGGNQKRQKCRWRQCLQFAMKRLLPSAGSGSGEGAGLRPYQTHQTHQKRPASARQLQLSSPLKAPWAVVTAPPGPVRDSRKQQAGRGSVLPQPDTDFVFLQEGTSSAMQMPGTAAASTEVPVQAAQCSAPSWVVALPQVKQETADAPEEWTAVTTFLTSSTLQSGFPSKAADPDLSPVKQEPPGPEEDGEEKKDDVSETTPAEEIGGVGTPVITEIFSLGGTRLRDAEAWLPRLHKLLAVNEKEYFTELQLKEEVL mint Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Isoform 1 can also repress transcription from unmethylated promoters 02D8B94EBD522F65 ten1_chick Teneurin-1 TENM1 ODZ1 Protein Odd Oz/ten-m homolog 1 TNM1 Tenascin-M1 Teneurin transmembrane protein 1 protein protein chick Gallus gallus (Chicken) Chicken MEQMDCKPYQPLSKVKHEVDLTYTSSSDESEDGRKQRQSYDSRETLNEYSQELRLNYNSQSRKRKNTDQSTQDMEFCETPHILCSGYQTDLHGVSEHSYPLEVGSDVDTETEGGASPDHALRMWMRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENDMPGSPHNQFTFRPLPPPPPPPHACTCTRKPPPAADSLQRRSMTTRSQPSPAAPTPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKCTALSATAITVTLALLLAYVIAVHLFGLTWQLQPVEGQLYENGVSKGNKGAESTDTTYSPIGGKVSDKTEKKVFQKGRAIDTGEVEIGAQVMQTIPPGLFWRFQITIHHPVYLKFNISLAKDSLLGIYGRRNIPPTHTQFDFVKLMDGKQLIKQEPKNSEEPQQAPRNLILTSLQETGFIEYMDQGAWHMAFYNDGKKVEQVFVLTTAIEVLDDCSTNCNGNGECISGHCHCFPGFLGPDCAKDSCPVLCSGNGEYEKGHCVCRNGWKGPECDVPEEQCIDPTCFGHGTCIMGVCICVPGYKGEICEEEDCLDPMCSGHGVCVQGECHCSAGWGGVNCETSLPICQEHCSGHGTFLLDVGLCSCEPQWTGSDCSTELCTLDCGSHGVCSRGICQCEEGWVGPTCEERTCHSHCAEHGQCKDGKCECSPGWEGDHCTIDGCPGLCYGNGRCTLDQNGWHCVCQVGWSGSGCNVVMEMACGDNLDNDGDGLTDCVDPDCCQQNNCYASPLCQGSPDPLDLIQHSQPPFSQHPPRLFYDRIRFLIGKESTHVIPGDISFESRRASVIRGQVVAIDGTPLVGVNVSFLHHDEYGYTISRQDGSFDLVAVGGISVTLVFDRSPFISEKRTLWLSWNRFVIVDKVVMQRAESDIPSCDVSSFISPNPIVLPSPLTAFGGSCPERGTVIPELQVVQEEIPIPSSFVKLSYLSSRTPGYKTLLRVILTHTTIPSGMTKVHLIIAVEGRLLQKWFPAAANLVYTFAWNKTDIYGQKVSGLAEAMVSVGYEYETCPDFILWEKRTVILQGFEMDASNLGGWSINKHHVLNPQSGIVHKGNGENMFISQQPPVISTMMGNGHQRSVSCSNCNGLALNSKLFAPVALTSGPDGSVYIGDFNFVRRIFPSGNSIGILELRNRDTRHSTSPAHKYYLAVDPVSESLYLSDTNTRRVYKAKSLIETKDLAKNVDVVAGTGDQCLPFDQSHCGDGGKASEASLNSPRGITIDKHGFIYFVDGTMIRKIDENGMITTIIGSNGLTSTQPLSCDSGMDITQVRLEWPTDLTVNPLDNSLYVLDNNIVLQISESRRVRIIAGRPIHCQVPGIDHFIVSKVAIHSTLESARAIAVSHSGIPYIRETDERKINRIQQVTTNGEISIIAGAPSDCDCKIDPNCDCFSGDGGYAKDAKLKAPSSLAVSPDDTLYVADLGNIRIRAVSRNKAHLSDTNMYEIASPADQELYQFTINGTHLHTLNLITRDYIYNFTYSGEGDVATITSSNGNSVHIRRDTSGLPLWVVVPGGQVYWLTISSNGVLKRVYAQGYNLALMTYPGNTGLLATKSDENGWTTVYEYDSDGHLTNATFPTGEVSSFHSDVEKLTRVELDTSNRENMVTATNFSATSTIYTLKQDNTQNIYRVSPDGSLRVTFASGMEITLNTEPHILAGVVSPTLGKCNISLPGEHNSNLIEWRQRREQTKGNISTFERRLRAHNRNLLSIDFDHVTRTGKIYDDHRKFTLRIMYDQTGRPVLWSPISKYNEVNITYSHSGLVTYIQRGTWTEKMEYDPSGNIISRTWADGKIWSYTYLEKSVMLLLHSQRRYIFEYDQSDYLLSVTMPSMVRHALQTMLSVGYYRNIYTPPDSGAAFIQDVTRDGRLLQTLYPGTGRRVLYKYSKQSRLSEILYDTTQVTFTYEESSGVIKTIHLMHDGFICTIRYRQTGPLIGRQIFRFSEEGLVNARFDYSYNNFRVTSMQAMINETPLPIDLYRYVDVSGRTEQFGKFSVINYDLNQVITTTVMKHTKIFSANGQVIEVQYEILKSIAYWMTIQYDNMGRMVICDIRVGVDANITRYFYEYDRDGQLQTVSVNDKTQWRYSYDLNGNINLLSHGNSARLTPLRYDLRDRITRLGEIQYKMDEDGFLRQRGNEIFEYNSNGLLNKAYNKVSGWTVQYCYDGLGRRVASKSSLGQHLQFFYADLSNPIRVTHLYNHSSSEITSLYYDLQGHLIAMELSSGEEYYVACDNTGTPLAVFSSRGQVIKEILYTPYGEIYQDTNPDFQVVIGFHGGLYDSLTKLVHLGQRDYDVIAGRWTTPNHHIWKHLNAVPQPFNLYSFENNYPVGRIQDVAKYTTDIGSWLELFGFQLHNVLPGFPKPEIEALETTYELLQLQTKTQEWDPGKTILGIQCELQKQLRNFISLDQLPMTPRYSDGKCYEGVKQPRFAAIPSVFGKGIKFAIKDGIVTADIIGVANEDSRRIAAILNNAHYLENLHFTIEGRDTHYFIKLGSLEEDLSLIGNTGGRRILENGVNVTVSQMTSVINGRTRRFADIQLQHGALCFNVRYGTTVEEEKNHVLEVARQRAVAQAWTKEQRRLQEGEEGIRAWTDGEKQQLLNTGRVQGYDGYFVLSVEQYLELSDSANNIHFMRQSEIGRR mint May function as a cellular signal transducer 230F03D1999037D2 srbs1_mouse Sorbin and SH3 domain-containing protein 1 Sorbs1 Kiaa1296 Sh3d5 Ponsin c-Cbl-associated protein SH3 domain protein 5 SH3P12 protein protein mouse Mus musculus Mouse MSSECDVGSSKAVVNGLASGNHGPDKDMDPTKICTGKGTVTLRASSSYRGTPSSSPVSPQESPKHESKSGLEPEDPSADEWKLSSSADTNGNAQPSPLAAKGYRSVHPSLSADKPQGSPLLNEVSSSHIETDSQDFPPTSRPSSAYPSTTIVNPTIVLLQHNRDPASERRAGEQDPVPTPAELTSPGRASERRAKDASRRVVRSAQDLSDVSTDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDVHSPRYSFSDDTKSPLSVPRSKSEMNYIEGEKVVKRSATLPLPARSSSLKSSPERNDWEPLDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGRPTNLEKDLSFCQAELEADLEKVETVNKSPSANSPQSSAVSPTPDITSEPPGYIYSSNFHAVKRESDGTPGGLASLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKVDRKGGNAHMISSSSVHSRTFHTSNALGPGCKHKKPLSAAKACISEILPSKFKPRLSAPSALLQEQKSVLLPSEKAQSCENLCVSLNDSKRGLPLRVGGSIENLLMRSRRDYDSKSSSTMSLQEYGTSSRRPCPLSRKAGLHFSMFYRDMHQINRAGLSLGSISSSSVRDLASHFERSSLTLARGELGASQEGSEHIPKHTVSSRITAFEQLIQRSRSMPSLDFSGRLSKSPTPVLSRSGLTSARSAESLLESTKLRPREMDGMDSGGVYASPTCSNMADHALSFRSLVPSEPLSICSDELDHCSNVSNDSREGSGGSVHGDFPKHRLNKCKGTCPASYTRFTTIRKHEQQSSRQSDWRSDSRGDKNSLLRNIHLMSPLPFRLKKPLQQHPRQPPPSDSSESPAGQKADLPCHDPQDQPHSAGKPQVPTRLSSRHTMARLSHNSEPPLDRPAGLEDCTRAINNGNPVPYSDHGLDRNNNPQSELAAAHGDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGLEMRPARAKFDFKAQTLKELPLQKGDVVYIYRQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPRKLAPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVLKRPLVKTPVDYIDLPYSSSPSRSATVSPQQPQAQQRRVTPDRSQPSLDLCSYQALYSYVPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKPLYL 07C9A74BD794E390 sorbs1-tenm1 4 6 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342581: original sequence: 1-300 : MEQMDCKPYQPLSKVKHEVDLTYTSSSDESEDGRKQRQSYDSRETLNEYSQELRLNYNSQSRKRKNTDQSTQDMEFCETPHILCSGYQTDLHGVSEHSYPLEVGSDVDTETEGGASPDHALRMWMRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENDMPGSPHNQFTFRPLPPPPPPPHACTCTRKPPPAADSLQRRSMTTRSQPSPAAPTPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 7 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 colocalization colocalization F3G mint mbd1-tenm1 4 5 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 6 immunostaining immunostaining predetermined predetermined participant predetermined unspecified role unspecified role neutral component neutral component over-expressed over expressed level over-expressed fixed cell fixed cell tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342448: original sequence: 1-300 : MEQMDCKPYQPLSKVKHEVDLTYTSSSDESEDGRKQRQSYDSRETLNEYSQELRLNYNSQSRKRKNTDQSTQDMEFCETPHILCSGYQTDLHGVSEHSYPLEVGSDVDTETEGGASPDHALRMWMRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENDMPGSPHNQFTFRPLPPPPPPPHACTCTRKPPPAADSLQRRSMTTRSQPSPAAPTPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 colocalization colocalization F5I homomint mint mbd1-tenm1-1 1 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 6 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role unspecified role unspecified role over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342470: original sequence: 1-300 : MEQMDCKPYQPLSKVKHEVDLTYTSSSDESEDGRKQRQSYDSRETLNEYSQELRLNYNSQSRKRKNTDQSTQDMEFCETPHILCSGYQTDLHGVSEHSYPLEVGSDVDTETEGGASPDHALRMWMRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENDMPGSPHNQFTFRPLPPPPPPPHACTCTRKPPPAADSLQRRSMTTRSQPSPAAPTPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 colocalization colocalization F4B homomint mint tenm1-sorbs1 3 6 western blot western blot Immuno blot Immuno blot predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342563: original sequence: 1-300 : MEQMDCKPYQPLSKVKHEVDLTYTSSSDESEDGRKQRQSYDSRETLNEYSQELRLNYNSQSRKRKNTDQSTQDMEFCETPHILCSGYQTDLHGVSEHSYPLEVGSDVDTETEGGASPDHALRMWMRGMKSEHSSCLSSRANSALSLTDTDHERKSDGENDMPGSPHNQFTFRPLPPPPPPPHACTCTRKPPPAADSLQRRSMTTRSQPSPAAPTPPTSTQDSVHLHNSWVLNSNIPLETRHFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 7 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 physical association physical association F3H mint tenm1-sorbs1-1 2 6 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342621: original sequence: 241-300 : HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 7 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed binding site binding region binding-associated region binding region full dna sequence full identification by DNA sequencing full dna sequence certain certain sequence position certain certain certain sequence position certain range MINT-1342630: original sequence: 626-683 : MHQINRAGLSLGSISSSSVRDLASHFERSSLTLARGELGASQEGSEHIPKHTVSSRI tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 physical association physical association F2 mint tenm1-mbd1 2 5 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 6 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined binding site binding region binding-associated region binding region deletion analysis deletion analysis certain certain sequence position certain certain certain sequence position certain intracellular domain range MINT-1342603: original sequence: 241-300 : HFLFKHGSGSSAIFSAASQNYPLTSNTVYSPPPRPLPRNTFSRPAFTFSKPYRCCNWKC Stoichiometry: 1.0 physical association physical association F4A homomint mint