MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature (0028-0836) 2001 Lachner M., O'Carroll D., Rea S., Mechtler K., Jenuwein T. Chromatin - Epigenetic interactions resulting in chromatin modulation no in vitro In vitro pull down pull down western blot western blot Immuno blot Immuno blot Lachner M., O'Carroll D., Rea S., Mechtler K., Jenuwein T. Chromatin - Epigenetic interactions resulting in chromatin modulation no Accepted 2010-JAN-10 by SKERRIEN (applied to all records created before 2005-Sep-01). Nature (0028-0836) 2001 h31_human Histone H3.1 H3FA H3FL H3FD H3FI H3FH H3FK H3FF H3FJ H3FB Histone H3/a Histone H3/b Histone H3/c Histone H3/d Histone H3/f Histone H3/h Histone H3/i Histone H3/j Histone H3/k Histone H3/l H3C1 HIST1H3A H3C2 HIST1H3B H3C3 H3FC HIST1H3C H3C4 HIST1H3D H3C6 HIST1H3E H3C7 HIST1H3F H3C8 HIST1H3G H3C10 HIST1H3H H3C11 HIST1H3I H3C12 HIST1H3J protein protein human Homo sapiens Human MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA DIP protein P68431 original sequence version: 78 DIP protein P68431 original sequence version: 79 DIP protein P68431 original sequence version: 76 DIP protein P68431 original sequence version: 92 DIP protein P68431 original sequence version: 87 DIP protein P68431 original sequence version: 101 DIP protein P68431 original sequence version: 130 DIP protein P68431 original sequence version: 115 9B89008EA50A0EF6 cbx1_human Chromobox protein homolog 1 CBX1 CBX Heterochromatin protein 1 homolog beta Modifier 1 protein M31 Heterochromatin protein p25 p25beta HP1Hsbeta protein protein human Homo sapiens Human MGKKQNKKKVEEVLEEEEEEYVVEKVLDRRVVKGKVEYLLKWKGFSDEDNTWEPEENLDCPDLIAEFLQSQKTAHETDKSEGGKRKADSDSEDKGEESKPKKKKEESEKPRGFARGLEPERIIGATDSSGELMFLMKWKNSDEADLVPAKEANVKCPQVVISFYEERLTWHSYPSEDDDKKDDKN DIP protein P83916 original sequence version: 29 DIP protein P83916 original sequence version: 105 DIP protein P83916 original sequence version: 101 BE687AF9C66E48E3 cbx5_mouse Chromobox protein homolog 5 Cbx5 Hp1a Heterochromatin protein 1 homolog alpha protein protein mouse Mus musculus Mouse MGKKTKRTADSSSSEDEEEYVVEKVLDRRMVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKKMKEGENNKPREKSEGNKRKSSFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLMKWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKESAKS DIP protein Q61686 original sequence version: 105 DIP protein Q61686 original sequence version: 91 DIP protein Q61686 original sequence version: 107 8AB87E2F00DB8C40 cbx2_mouse Chromobox protein homolog 2 Cbx2 M33 Modifier 3 protein protein protein mouse Mus musculus Mouse MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVTSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSAAKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGMAGSPSRGGIWQSSIVHYMNRMSQSQVQAASRLALKAQATNKCGLGLDLKVRTQKGGELGGSPAGGKVPKAPGGGAAEQQRGNHSGSPGAQLAPTQELSLQVLDLQSVKNGVPGVGLLARHAPAKAIPATNPATGKGPGSGPTGANMTNAPTDNNKGEKLTCKATALPAPSVKRDTVKSVAASGGQEGHTAPGEGRKPPALSELSTGEENSSSDSDPDSTSLPSAAQNLSVAIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY DIP protein P30658 original sequence version: 76 F89EF3CEF14ACA72 h4_pladu Histone H4 protein protein pladu Platynereis dumerilii (Dumeril's clam worm) MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG A9E5DFD3F8B97598 pax5_mouse Paired box protein Pax-5 Pax5 Pax-5 B-cell-specific transcription factor protein protein mouse Mus musculus Mouse MDLEKNYPTPRTIRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQTTEYSAMASLAGGLDDMKANLTSPTPADIGSSVPGPQSYPIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVPGSEFSGSPYSHPQYSSYNDSWRFPNPGLLGSPYYYSPAARGAAPPAAATAYDRH D703E94808DE8EC8 cbx3_mouse Chromobox protein homolog 3 Cbx3 Heterochromatin protein 1 homolog gamma Modifier 2 protein M32 protein protein mouse Mus musculus Mouse MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEDFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMFLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ DIP protein P23198 original sequence version: 123 DIP protein P23198 original sequence version: 121 DIP protein P23198 original sequence version: 111 2FF3AD53B883E27E suv91_human Histone-lysine N-methyltransferase SUV39H1 SUV39H1 SUV39H KMT1A Suppressor of variegation 3-9 homolog 1 Position-effect variegation 3-9 homolog Histone H3-K9 methyltransferase 1 Lysine N-methyltransferase 1A protein protein human Homo sapiens Human MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF DIP protein O43463 original sequence version: 137 DIP protein O43463 original sequence version: 157 DIP protein O43463 original sequence version: 116 AF6F959AD20C6C76 h3fa-pax5 1 2 unspecified role unspecified role bait bait ser 10 opser O-phospho-L-serine (2S)-2-amino-3-(phosphonooxy)propanoic acid 2-amino-3-hydroxypropanoic acid 3-phosphate 2-azanyl-3-(phosphonooxy)propanoic acid ACT_SITE Phosphoserine intermediate MOD_RES Phosphoserine O-phospho-L-serine O-phosphonoserine O-phosphorylated L-serine O3-phosphoserine serine phosphate ester OPSer Phospho Phospho Seryl Phosphorylation phosphorylations certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 7 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h3fa-cbx2 1 5 unspecified role unspecified role prey prey in vitro In vitro 2 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h3fa-cbx5 1 2 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) 4 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h3fa-cbx1 1 2 unspecified role unspecified role bait bait lys 9 n6me2lys N6,N6-dimethyl-L-lysine (2S)-2-amino-6-(dimethylamino)hexanoic acid MOD_RES N6,N6-dimethyllysine N(zeta)-dimethyllysine N6,N6-dimethyl-L-lysine N6,N6-dimethylated L-lysine epsilon-dimethyllysine lysine derivative Lys(y) Dimethyl N6Me2Lys di-Methylation dimethylk certain certain sequence position certain certain certain sequence position certain chemical synthesis Chemical synthesis (Chemical synthesis) 3 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h3fa-cbx3 1 2 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) 8 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h3fa-suv39h1 1 2 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) 9 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h4f2-pax5 1 6 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) 7 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place. h4f2-cbx2 1 6 unspecified role unspecified role bait bait chemical synthesis Chemical synthesis (Chemical synthesis) 5 unspecified role unspecified role prey prey in vitro In vitro physical association physical association Prey is myc tagged. AA1-20 of bait used in the interaction. Revisit when Swiss Prot demerges. Revisit when Protein Editor in place.