MINT MINT, Dpt of Biology, University of Rome Tor Vergata MINT http://mint.bio.uniroma2.it/mint url>http://mint.bio.uniroma2.it/mint/ https://mint.bio.uniroma2.it MINT-[0-9]+ https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac} The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules. http://mint.bio.uniroma2.it The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (0092-8674) 1997 Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no in vivo in vivo coip coimmunoprecipitation co-immunoprecipitation CoIp immunoprecipitation Co-IP co-immunoprecipitation CoIp immunoprecipitation Co-IP coip predetermined predetermined participant predetermined Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no Cell (0092-8674) 1997 The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (0092-8674) 1997 Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no in vitro In vitro pull down pull down predetermined predetermined participant predetermined Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no Cell (0092-8674) 1997 The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (0092-8674) 1997 Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no in vitro In vitro experimental interac experimental interaction detection experimental interac predetermined predetermined participant predetermined Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no Cell (0092-8674) 1997 The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (0092-8674) 1997 Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no in vitro In vitro filter binding filter binding Filter overlay assay Filter overlay assay predetermined predetermined participant predetermined Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no Cell (0092-8674) 1997 The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. Cell (0092-8674) 1997 Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no in vivo in vivo 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence Liu Q., Fischer U., Wang F., Dreyfuss G. Virus - Publications including interactions involving viral proteins no Cell (0092-8674) 1997 ruxg_human Small nuclear ribonucleoprotein G SNRPG PBSCG Sm protein G protein protein human Homo sapiens Human MSKAHPPELKKFMDKKLSLKLNGGRHVQGILRGFDPFMNLVIDECVEMATSGQQNNIGMVVIRGNSIIMLEALERV DIP protein P62308 original sequence version: 69 DIP protein P62308 original sequence version: 92 DIP protein P62308 original sequence version: 78 DIP protein P62308 original sequence version: 126 623302BF6BE758FE gemi2_human Gem-associated protein 2 GEMIN2 SIP1 Component of gems 2 Survival of motor neuron protein-interacting protein 1 protein protein human Homo sapiens Human MRRAELAGLKTMAWVPAESAVEELMPRLLPVEPCDLTEGFDPSVPPRTPQEYLRRVQIEAAQCPDVVVAQIDPKKLKRKQSVNISLSGCQPAPEGYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWKKFCLGEKLCADGAVGPATNESPGIDYVQIGFPPLLSIVSRMNQATVTSVLEYLSNWFGERDFTPELGRWLYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVDSKDDERVPALNLLICLVSRYFDQRDLADEPS DIP protein O14893 original sequence version: 146 DIP protein O14893 original sequence version: 114 3232F410EA98EB81 ruxe_chick Small nuclear ribonucleoprotein E SNRPE Sm protein E protein protein chick Gallus gallus (Chicken) Chicken MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN Associated with snRNP U1, U2, U4/U6 and U5 mint 7D8881CE1F4FA2FD snrpa_human U1 small nuclear ribonucleoprotein A SNRPA protein protein human Homo sapiens Human MAVPETRPNHTIYINNLNEKIKKDELKKSLYAIFSQFGQILDILVSRSLKMRGQAFVIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKMKGTFVERDRKREKRKPKSQETPATKKAVQGGGATPVVGAVQGPVPGMPPMTQAPRIMHHMPGQPPYMPPPGMIPPPGLAPGQIPPGAMPPQQLMPGQMPPAQPLSENPPNHILFLTNLPEETNELMLSMLFNQFPGFKEVRLVPGRHDIAFVEFDNEVQAGAARDALQGFKITQNNAMKISFAKK DIP protein P09012 original sequence version: 99 9426E83EE5A22894 rsmb_human Small nuclear ribonucleoprotein-associated proteins B and B' Sm protein B/B' SNRPB COD SNRPB1 protein protein human Homo sapiens Human MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNSKQAEREEKRVLGLVLLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGIGRAAGRGIPAGVPMPQAPAGLAGPVRGVGGPSQQVMTPQGRGTVAAAAAAATASIAGAPTQYPPGRGGPPPPMGRGAPPPGMMGPPPGMRPPMGPPMGIPPGRGTPMGMPPPGMRPPPPGMRGPPPPGMRPPRP DIP protein P14678 original sequence version: 150 DIP protein P14678 original sequence version: 131 DIP protein P14678 original sequence version: 186 F2E1D5E11A601170 smd2_mouse Small nuclear ribonucleoprotein Sm D2 Snrpd2 snRNP core protein D2 protein protein mouse Mus musculus Mouse MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKSGKGKKKSKPVNKDRYISKMFLRGDSVIVVLRNPLIAGK D986059D82B7E045 smn_human Survival motor neuron protein SMN1 SMN SMNT SMN2 SMNC Component of gems 1 Gemin-1 protein protein human Homo sapiens Human MAMSSGGSGGGVPEQEDSVLFRRGTGQSDDSDIWDDTALIKAYDKAVASFKHALKNGDICETSGKPKTTPKRKPAKKNKSQKKNTAASLQQWKVGDKCSAIWSEDGCIYPATIASIDFKRETCVVVYTGYGNREEQNLSDLLSPICEVANNIEQNAQENENESQVSTDESENSRSPGNKSDNIKPKSAPWNSFLPPPPPMPGPRLGPGKPGLKFNGPPPPPPPPPPHLLSCWLPPFPSGPPIIPPPPPICPDSLDDADALGSMLISWYMSGYHTGYYMGFRQNQKEGRCSHSLN DIP protein Q16637 original sequence version: 129 DIP protein Q16637-1 original sequence version: 185 DIP protein Q16637 original sequence version: 182 DIP protein Q16637 original sequence version: 149 8A9A2A94192DCB9B ruxf_mouse Small nuclear ribonucleoprotein F Snrpf Sm protein F protein protein mouse Mus musculus Mouse MSLPLNPKPFLNGLTGKPVMVKLKWGMEYKGYLVSVDGYMNMQLANTEEYIDGALSGHLGEVLIRCNNVLYIRGVEEEEEDGEMRE Associated with snRNP U1, U2, U4/U6 and U5 mint 416B88D575DAE58A smd1_mouse Small nuclear ribonucleoprotein Sm D1 Snrpd1 snRNP core protein D1 Sm-D autoantigen protein protein mouse Mus musculus Mouse MKLVRFLMKLSHETVTIELKNGTQVHGTITGVDVSMNTHLKAVKMTLKNREPVQLETLSIRGNNIRYFILPDSLPLDTLLVDVEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA mint 0C81C94BF98E0810 smd3_mouse Small nuclear ribonucleoprotein Sm D3 Snrpd3 snRNP core protein D3 protein protein mouse Mus musculus Mouse MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR 59A6E78E860AA3E0 smn1-snrpd1 1 14 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527836: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association mint smn1-snrpf 1 13 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527867: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association homomint mint smn1-gemin2-1 1 7 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527877: original sequence: 13-44 : PEQEDSVLFRRGTGQSDDSDIWDDTALIKAY Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpd2 1 11 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527887: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association mint smn1-snrpe 1 8 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527921: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpb 1 10 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527965: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpg 1 6 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528006: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpa 1 9 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpd3 1 15 unspecified role unspecified role prey prey physiological level physiological level endogenous level endogenous endogenous endogenous level Stoichiometry: 1.0 12 unspecified role unspecified role bait bait physiological level physiological level endogenous level endogenous endogenous endogenous level binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528064: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 physical association physical association homomint mint smn1-snrpe-1 2 8 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527848: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpb-1 2 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527911: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 10 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpd3-1 2 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527943: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 15 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpd2-1 2 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527975: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 11 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction mint smn1-gemin2-2 2 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528054: original sequence: 13-44 : PEQEDSVLFRRGTGQSDDSDIWDDTALIKAY Stoichiometry: 1.0 7 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpd1-1 2 14 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528074: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 direct interaction direct interaction mint smn1-snrpf-1 2 13 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528084: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpg-1 2 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528094: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 6 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction homomint mint smn1-snrpb-2 3 10 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 12 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527899: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 association association homomint mint smn1-snrpd2-2 3 12 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527931: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 11 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 association association mint smn1-snrpd1-2 3 14 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 12 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1527953: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 association association mint smn1-snrpd3-2 3 15 unspecified role unspecified role unspecified role unspecified role purified purified Stoichiometry: 1.0 12 unspecified role unspecified role unspecified role unspecified role purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528104: original sequence: 240-267 : PPIIPPPPPICPDSLDDADALGSMLIS Stoichiometry: 1.0 association association homomint mint smn1-gemin2-3 5 12 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role bait bait over-expressed over expressed level over-expressed binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528026: original sequence: 13-44 : PEQEDSVLFRRGTGQSDDSDIWDDTALIKAY tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 7 nucleotide sequence nucleotide sequence identification sequence cloning sequence cloning nucleotide sequence predetermined predetermined participant predetermined unspecified role unspecified role prey prey over-expressed over expressed level over-expressed tagged molecule tag tag undetermined undetermined sequence position undetermined undetermined undetermined sequence position undetermined Stoichiometry: 1.0 physical association physical association homomint mint smn1-gemin2-4 4 12 unspecified role unspecified role bait bait purified purified binding site binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain range MINT-1528044: original sequence: 13-44 : PEQEDSVLFRRGTGQSDDSDIWDDTALIKAY Stoichiometry: 1.0 7 unspecified role unspecified role prey prey purified purified Stoichiometry: 1.0 direct interaction direct interaction homomint mint