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  <entry>
    <source releaseDate="2022-02-03">
      <names>
        <shortLabel>MINT</shortLabel>
        <fullName>MINT, Dpt of Biology, University of Rome Tor Vergata</fullName>
        <alias type="synonym" typeAc="MI:1041">MINT</alias>
      </names>
      <bibref>
        <xref>
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      </bibref>
      <xref>
        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0471" refType="identity" refTypeAc="MI:0356"/>
        <secondaryRef db="mint" dbAc="MI:0471" id="MINT-80017" refType="identity" refTypeAc="MI:0356"/>
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      </xref>
      <attributeList>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it/mint</attribute>
        <attribute name="url" nameAc="MI:0614">url&amp;gt;http://mint.bio.uniroma2.it/mint/</attribute>
        <attribute name="url" nameAc="MI:0614">https://mint.bio.uniroma2.it</attribute>
        <attribute name="id-validation-regexp" nameAc="MI:0628">MINT-[0-9]+</attribute>
        <attribute name="search-url" nameAc="MI:0615">https://mint.bio.uniroma2.it/index.php/results-interactions/?id=${ac}</attribute>
        <attribute name="definition">The Molecular INTeraction database (MINT) is a relational database designed to store interactions between biological molecules.</attribute>
        <attribute name="url" nameAc="MI:0614">http://mint.bio.uniroma2.it</attribute>
      </attributeList>
    </source>
    <experimentList>
      <experimentDescription id="1">
        <names>
          <fullName>Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex.</fullName>
        </names>
        <bibref>
          <xref>
            <primaryRef db="pubmed" dbAc="MI:0446" id="7552746" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="doi" dbAc="MI:0574" id="10.1038/nsb0995-752" refType="secondary-ac" refTypeAc="MI:0360"/>
            <secondaryRef db="mint" dbAc="MI:0471" id="MINT-5220407" refType="primary-reference" refTypeAc="MI:0358"/>
            <secondaryRef db="mint" dbAc="MI:0471" id="MINT-1506600" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8581537" refType="identity" refTypeAc="MI:0356"/>
          </xref>
          <attributeList>
            <attribute name="publication title" nameAc="MI:1091">Nucleotide mimicry in the crystal structure of the uracil-DNA glycosylase-uracil glycosylase inhibitor protein complex.</attribute>
            <attribute name="journal" nameAc="MI:0885">Nat. Struct. Biol. (1072-8368)</attribute>
            <attribute name="publication year" nameAc="MI:0886">1995</attribute>
            <attribute name="author-list" nameAc="MI:0636">Savva R., Pearl LH.</attribute>
            <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
            <attribute name="uniprot-dr-export">no</attribute>
          </attributeList>
        </bibref>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-1506600" refType="identity" refTypeAc="MI:0356"/>
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          <secondaryRef db="pubmed" dbAc="MI:0446" id="7552746" refType="primary-reference" refTypeAc="MI:0358"/>
        </xref>
        <hostOrganismList>
          <hostOrganism ncbiTaxId="-1">
            <names>
              <shortLabel>in vitro</shortLabel>
              <fullName>In vitro</fullName>
            </names>
          </hostOrganism>
        </hostOrganismList>
        <interactionDetectionMethod>
          <names>
            <shortLabel>x-ray diffraction</shortLabel>
            <fullName>x-ray crystallography</fullName>
            <alias type="go synonym" typeAc="MI:0303">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">X-ray</alias>
            <alias type="synonym" typeAc="MI:1041">x-ray diffraction</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0114" refType="identity" refTypeAc="MI:0356"/>
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          </xref>
        </interactionDetectionMethod>
        <participantIdentificationMethod>
          <names>
            <shortLabel>nucleotide sequence</shortLabel>
            <fullName>nucleotide sequence identification</fullName>
            <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
            <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
            <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-958" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </participantIdentificationMethod>
        <attributeList>
          <attribute name="author-list" nameAc="MI:0636">Savva R., Pearl LH.</attribute>
          <attribute name="dataset" nameAc="MI:0875">Virus - Publications including interactions involving viral proteins</attribute>
          <attribute name="uniprot-dr-export">no</attribute>
          <attribute name="journal" nameAc="MI:0885">Nat. Struct. Biol. (1072-8368)</attribute>
          <attribute name="publication year" nameAc="MI:0886">1995</attribute>
        </attributeList>
      </experimentDescription>
    </experimentList>
    <interactorList>
      <interactor id="2">
        <names>
          <shortLabel>ungi_bppb2</shortLabel>
          <fullName>Uracil-DNA glycosylase inhibitor</fullName>
          <alias type="gene name" typeAc="MI:0301">UGI</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P14739" version="SP_38" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1025973" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR024062"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1EUI"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LQG"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LQM"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UDI"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UGH"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UGI"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UUG"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2J8X"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2UGI"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2UUG"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2ZHX"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4LYL"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR043805"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LYD"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="6LYE"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10684">
          <names>
            <shortLabel>bppb2</shortLabel>
            <fullName>Bacteriophage PBS2</fullName>
          </names>
        </organism>
        <sequence>MTNLSDIIEKETGKQLVIQESILMLPEEVEEVIGNKPESDILVHTAYDESTDENVMLLTSDAPEYKPWALVIQDSNGENKIKML</sequence>
        <attributeList>
          <attribute name="crc64">C07DCF9DB101BC2A</attribute>
        </attributeList>
      </interactor>
      <interactor id="3">
        <names>
          <shortLabel>ung_hhv11</shortLabel>
          <fullName>Uracil-DNA glycosylase</fullName>
          <alias type="orf name" typeAc="MI:0306">UL2</alias>
          <alias type="gene name synonym" typeAc="MI:0302">UNG</alias>
        </names>
        <xref>
          <primaryRef db="uniprotkb" dbAc="MI:0486" id="P10186" version="SP_58" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="MINT-1506602" refType="intact-secondary"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="B9VQC9" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
          <secondaryRef db="uniprotkb" dbAc="MI:0486" id="Q09ID1" version="SP_70" refType="secondary-ac" refTypeAc="MI:0360"/>
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          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="5AYS"/>
          <secondaryRef db="refseq" dbAc="MI:0481" id="YP_009137076.1"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0004844" version="SP_126"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0006284" version="SP_126"/>
          <secondaryRef db="go" dbAc="MI:0448" id="GO:0042025" version="SP_126"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UDG"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UDH"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1LAU"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="1UDI"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C56"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="2C53"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR018085"/>
          <secondaryRef db="rcsb pdb" dbAc="MI:0460" id="4L5N"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR036895"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR002043" version="SP_126"/>
          <secondaryRef db="interpro" dbAc="MI:0449" id="IPR005122" version="SP_126"/>
        </xref>
        <interactorType>
          <names>
            <shortLabel>protein</shortLabel>
            <fullName>protein</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0326" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-619654" refType="identity" refTypeAc="MI:0356"/>
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            <secondaryRef db="so" dbAc="MI:0601" id="SO:0000358" refType="see-also" refTypeAc="MI:0361"/>
          </xref>
        </interactorType>
        <organism ncbiTaxId="10299">
          <names>
            <shortLabel>hhv11</shortLabel>
            <fullName>Human herpesvirus 1 (strain 17) (HHV-1)</fullName>
            <alias type="synonym" typeAc="MI:1041">Human herpes simplex virus 1</alias>
            <alias type="synonym" typeAc="MI:1041">HHV-1</alias>
          </names>
        </organism>
        <sequence>MKRACSRSPSPRRRPSSPRRTPPRDGTPPQKADADDPTPGASNDASTETRPGSGGEPAACRSSGPAALLAALEAGPAGVTFSSSAPPDPPMDLTNGGVSPAATSAPLDWTTFRRVFLIDDAWRPLMEPELANPLTAHLLAEYNRRCQTEEVLPPREDVFSWTRYCTPDEVRVVIIGQDPYHHPGQAHGLAFSVRANVPPPPSLRNVLAAVKNCYPEARMSGHGCLEKWARDGVLLLNTTLTVKRGAAASHSRIGWDRFVGGVIRRLAARRPGLVFMLWGTHAQNAIRPDPRVHCVLKFSHPSPLSKVPFGTCQHFLVANRYLETRSISPIDWSV</sequence>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
          <attribute name="function" nameAc="MI:0613">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine</attribute>
          <attribute name="crc64">7CD3B74FB43F00CD</attribute>
        </attributeList>
      </interactor>
    </interactorList>
    <interactionList>
      <interaction id="4">
        <names>
          <shortLabel>ugi-ung-6</shortLabel>
        </names>
        <xref>
          <primaryRef db="mint" dbAc="MI:0471" id="MINT-24794" refType="identity" refTypeAc="MI:0356"/>
          <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8581576" refType="identity" refTypeAc="MI:0356"/>
        </xref>
        <experimentList>
          <experimentRef>1</experimentRef>
        </experimentList>
        <participantList>
          <participant id="5">
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-1506617" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>3</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>nucleotide sequence</shortLabel>
                  <fullName>nucleotide sequence identification</fullName>
                  <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0078" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
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            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="6">
                <names>
                  <shortLabel>tagged molecule</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-1506618" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
                <featureType>
                  <names>
                    <shortLabel>tag</shortLabel>
                    <fullName>tag</fullName>
                  </names>
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                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
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                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
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                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <stoichiometry value="1"/>
            <attributeList>
              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
            </attributeList>
          </participant>
          <participant id="7">
            <xref>
              <primaryRef db="mint" dbAc="MI:0471" id="MINT-1506624" refType="identity" refTypeAc="MI:0356"/>
            </xref>
            <interactorRef>2</interactorRef>
            <participantIdentificationMethodList>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>nucleotide sequence</shortLabel>
                  <fullName>nucleotide sequence identification</fullName>
                  <alias type="go synonym" typeAc="MI:0303">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">sequence cloning</alias>
                  <alias type="synonym" typeAc="MI:1041">nucleotide sequence</alias>
                </names>
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                </xref>
              </participantIdentificationMethod>
              <participantIdentificationMethod>
                <names>
                  <shortLabel>predetermined</shortLabel>
                  <fullName>predetermined participant</fullName>
                  <alias type="synonym" typeAc="MI:1041">predetermined</alias>
                </names>
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                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0396" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1465" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </participantIdentificationMethod>
            </participantIdentificationMethodList>
            <biologicalRole>
              <names>
                <shortLabel>unspecified role</shortLabel>
                <fullName>unspecified role</fullName>
              </names>
              <xref>
                <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="intact" dbAc="MI:0469" id="EBI-77781" refType="identity" refTypeAc="MI:0356"/>
                <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
              </xref>
            </biologicalRole>
            <experimentalRoleList>
              <experimentalRole>
                <names>
                  <shortLabel>unspecified role</shortLabel>
                  <fullName>unspecified role</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0499" refType="identity" refTypeAc="MI:0356"/>
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                </xref>
              </experimentalRole>
            </experimentalRoleList>
            <experimentalPreparationList>
              <experimentalPreparation>
                <names>
                  <shortLabel>purified</shortLabel>
                  <fullName>purified</fullName>
                </names>
                <xref>
                  <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0350" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-1537811" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                </xref>
              </experimentalPreparation>
            </experimentalPreparationList>
            <featureList>
              <feature id="8">
                <names>
                  <shortLabel>tagged molecule</shortLabel>
                </names>
                <xref>
                  <primaryRef db="mint" dbAc="MI:0471" id="MINT-1506625" refType="identity" refTypeAc="MI:0356"/>
                  <secondaryRef db="intact" dbAc="MI:0469" id="EBI-8581590" refType="identity" refTypeAc="MI:0356"/>
                </xref>
                <featureType>
                  <names>
                    <shortLabel>tag</shortLabel>
                    <fullName>tag</fullName>
                  </names>
                  <xref>
                    <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0507" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="intact" dbAc="MI:0469" id="EBI-456738" refType="identity" refTypeAc="MI:0356"/>
                    <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                  </xref>
                </featureType>
                <featureRangeList>
                  <featureRange>
                    <startStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </startStatus>
                    <endStatus>
                      <names>
                        <shortLabel>undetermined</shortLabel>
                        <fullName>undetermined sequence position</fullName>
                        <alias type="synonym" typeAc="MI:1041">undetermined</alias>
                      </names>
                      <xref>
                        <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0339" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="intact" dbAc="MI:0469" id="EBI-448295" refType="identity" refTypeAc="MI:0356"/>
                        <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
                      </xref>
                    </endStatus>
                  </featureRange>
                </featureRangeList>
              </feature>
            </featureList>
            <stoichiometry value="1"/>
            <attributeList>
              <attribute name="comment" nameAc="MI:0612">Stoichiometry: 1.0</attribute>
            </attributeList>
          </participant>
        </participantList>
        <interactionType>
          <names>
            <shortLabel>direct interaction</shortLabel>
            <fullName>direct interaction</fullName>
          </names>
          <xref>
            <primaryRef db="psi-mi" dbAc="MI:0488" id="MI:0407" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="intact" dbAc="MI:0469" id="EBI-608833" refType="identity" refTypeAc="MI:0356"/>
            <secondaryRef db="pubmed" dbAc="MI:0446" id="14755292" refType="primary-reference" refTypeAc="MI:0358"/>
          </xref>
        </interactionType>
        <attributeList>
          <attribute name="comment" nameAc="MI:0612">In the xray complex 1udi, P10186 is chain E and P14739 is chain I Resolution 2.700</attribute>
          <attribute name="comment" nameAc="MI:0612">mint</attribute>
        </attributeList>
      </interaction>
    </interactionList>
  </entry>
</entrySet>