IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Frontiers in chemistry 2020 imex curation Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F., Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F. Virus - Publications including interactions involving viral proteins Coronavirus - Interactions investigated in the context of Coronavirus a "methods-lite" publication zhulfl@ecust.edu.cn,baifang@shanghaitech.edu.cn Only protein-protein interactions imex curation in vitro In vitro ms interact detect detection by mass spectrometry ms interact detect predetermined predetermined participant predetermined Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F., Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F. Virus - Publications including interactions involving viral proteins a "methods-lite" publication zhulfl@ecust.edu.cn,baifang@shanghaitech.edu.cn Accepted 2021-AUG-16 AT 10:34 BST AT 10:34 BST by KALPANAP Frontiers in chemistry 2020 Only protein-protein interactions imex curation imex curation Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein. Frontiers in chemistry 2020 imex curation Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F., Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F. Virus - Publications including interactions involving viral proteins Coronavirus - Interactions investigated in the context of Coronavirus a "methods-lite" publication zhulfl@ecust.edu.cn,baifang@shanghaitech.edu.cn Only protein-protein interactions imex curation in vitro In vitro spr surface plasmon resonance Optical biosensor BIAcore(r) BIAcore(r) Optical biosensor spr predetermined predetermined participant predetermined Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F., Li B., Wang L., Ge H., Zhang X., Ren P., Guo Y., Chen W., Li J., Zhu W., Chen W., Zhu L., Bai F. Virus - Publications including interactions involving viral proteins a "methods-lite" publication zhulfl@ecust.edu.cn,baifang@shanghaitech.edu.cn Accepted 2021-AUG-16 AT 10:34 BST AT 10:34 BST by KALPANAP Frontiers in chemistry 2020 Only protein-protein interactions imex curation imex curation spike_sars2 Spike glycoprotein S E2 Peplomer protein 2 protein protein SARS-CoV-2 SARS-CoV-2 SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 2019-nCoV MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT n-acetylneuraminic acid N-acetylneuraminic acid 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid Aceneuramic acid aceneuramic acid acide aceneuramique acidium aceneuramicum acido aceneuramico N-Acetylneuraminic acid Neu5Ac NeuAc O-sialic acid WURCS=2.0/1,1,0/[Aad21122h-2x_2-6_5*NCC/3=O]/1/ 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid small molecule small molecule chemical synthesis Chemical synthesis (Chemical synthesis) n_acetylneuraminic acid-s-1 1 3 unspecified role unspecified role neutral component neutral component rbd sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 4 unspecified role unspecified role neutral component neutral component direct interaction direct interaction 5 n_acetylneuraminic acid-s-2 2 3 unspecified role unspecified role bait bait rbd sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain 4 unspecified role unspecified role prey prey direct interaction direct interaction 6