HPIDb Host Pathogen Interaction database http://www.agbase.msstate.edu/hpi/main.html Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Journal of virology 2016 imex curation Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Only protein-protein interactions imex curation in vitro In vitro comig non denat gel comigration in non denaturing gel electrophoresis comig non denat gel weight by comassie molecular weight estimation by coomasie staining weight by comassie Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Accepted 2017-FEB-01 AT 13:07 GMT AT 13:07 GMT by ORCHARD Journal of virology 2016 imex curation Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Journal of virology 2016 imex curation Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Only protein-protein interactions imex curation in vitro In vitro solution sedimentati cosedimentation in solution solution sedimentati predetermined predetermined participant predetermined Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Accepted 2017-FEB-01 AT 13:07 GMT AT 13:07 GMT by ORCHARD Journal of virology 2016 imex curation Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer. Journal of virology 2016 imex curation Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Only protein-protein interactions imex curation in vitro In vitro molecular sieving molecular sieving Gel Filtration Size Exclusion Chromatography Size Exclusion Chromatography Gel Filtration Sizing column weight by comassie molecular weight estimation by coomasie staining weight by comassie Gottipati K., Holthauzen LM., Ruggli N., Choi KH., Gottipati K., Holthauzen LM., Ruggli N., Choi KH. Virus - Publications including interactions involving viral proteins kychoi@utmb.edu Accepted 2017-FEB-01 AT 13:07 GMT AT 13:07 GMT by ORCHARD Journal of virology 2016 imex curation f1rk46_pig Histone acetyltransferase CREBBP protein protein pig Sus scrofa (Pig) Pig MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLVPDAASKHKQLSELLRGGSSSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLGAMGKSPLNQGDSSAPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAETLTQVSPQMASHAGLNTAQTGGMTKMGMAGNTSPFGQPFSQAGGQQMGAPGVNPQIPGKQSMVNSLPPFPADIKNASVTSVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKNCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYLNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPSLISESALPTSLGATNPLMSDGATSGNIGPLSTLPSAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGTQPPGIPQAQPVRPPNGPMPLPVNRMQVSQGMNSFTPMSLGNVQLPQAPMGPRAASPMNHSVPMNSMGSVPGMAISPSRMPQPPNMMGTHANNMMAQAPAQNQFLPQNQFPSASGAMSVNSVGLGQPAAQAAVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHQTPPPASTAAGLPSLQHPVAPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSASQSQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKAEVKTEDTEPDASEPKGEPGSGMMEEDLQGSSQVKEETDTTEQKSEPMEVDEKKPEVKVEAKEEEDGGANGAASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRTRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHTHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSAGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNGMPPGRTGMVTPGSQMAPVGLNVPRPNQVSGPVVPNLPPGQWQQAPIPQQQPMPGMPRPVMSMPAQPAVAGPRMPSVQPPRSISPGALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVASQPGLQAQPSLQAQPGLQPQPGLHQQPGLQNLNAMQAGGPRPGVPPQQQTMGGLNPQGQALNIMNPGHSPSMASMNPQYREMLRRQLLQQQQQQQQQQQQQQGGAGMAGGMAGHGQFQQPQGPGGYPPAMQQQRMQQHLPIQGGSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQMATSLSSQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL C9315CE56A956FCB q68871_9flav Autoprotease p20 Capsid protein C Cysteine protease NS2 E(rns) glycoprotein Envelope glycoprotein E1 Envelope glycoprotein E2 Genome polyprotein N-terminal protease NS5B Non-structural protein 2 Non-structural protein 2-3 Non-structural protein 3 Non-structural protein 4A Non-structural protein 4B Non-structural protein 5A RNA-directed RNA polymerase Serine protease NS3 gp33 gp44/48 gp55 Viroporin p7 protein protein classical swine fever virus - alfort/187 classical swine fever virus - alfort/187 MELNHFELLYKTNKQKPMGVEEPVYDATGKPLFGDPSEVHPQSTLKLPHDRGRGNIKTTLKNLPRKGDCRSGNHLGPVSGIYVKPGPVFYQDYMGPVYHRAPLEFFSEAQFCEVTKRIGRVTGSDGRLYHIYVCIDGCILLKLAKRGEPRTLKWIRNFTDCPLWVTSCSDDGASGSKEKKPDRINKGKLKIAPKEHEKDSRTKPPDATIVVEGVKYQVKKKGKVKGKNTQDGLYHNKNKPPESRKKLEKALLAWAVIAIMLYQPVEAENITQWNLSDNGTNGIQHAMYLRGISRSLHGIWPEKICKGVPTYLATDTELKEIQGMMDASEGTNYTCCKLQRHEWNKHGWCNWYNIDPWIQLMNRTQANLAEGPPAKECAVTCRYDKDADVNVVTQARNRPTTLTGCKKGKNFSFAGTVIEGPCNFNVSVEDILYGDHECGSLLQDTALYLVDGMTNTIENARQGAARVTSWLGRQLRIAGKRLEGRSKTWFGAYALSPYCNVTSKIGYIWYTNNCTPACLPKNTKIIGPGKFDTNAEDGKILHEMGGHLSEFLLLSLVVLSDFAPETASALYLILHYVIPQSHEEPEGCDTNQLNLTVELRTEDVIPSSVWNVGKYVCVRPDWWPYETKVALLFEEAGQVVKLALRALRDLTRVWNSASTTAFLICLIKVLRGQIVQGVIWLLLVTGAQGQLACKEDYRYAISSTNEIGLLGAGGLTTTWKEYNHDLQLNDGTVKAICVAGSFKVTALNVVSRRYLASLHKEALPTSVTFELLFDGTNPSTEEMGDDFGFGLCPFDTSPVVKGKYNTTLLNGSAFYLVCPIGWTGVIECTAVSPTTLRTEVVKTFRRDKPFPHRMDCVTTTVENEDLFYCKLGGNWTCVKGEPVVYTGGLVKQCRWCGFDFNEPDGLPHYPIGKCILANETGYRIVDSTDCNRDGVVISTEGSHECLIGNTTVKVHASDERLGPMPCRPKEIVSSAGPVRKTSCTFNYAKTLKNKYYEPRDSYFQQYMLKGEYQYWFDLDVTDRHSDYFAEFVVLVVVALLGGRYILWLIVTYIVLTEQLAAGLPLGQGEVVLIGNLITHTDIEVVVYFLLLYLVMRDEPIKKWILLLFHAMTNNPVKTITVALLMVSGVARGGKIDGGWQRLPETSFDIQLALTVIVVAVMLLAKRDPTTVPLVVTVATLRTAKMTNGLSTDIAIATVSTALLTWTYISDYYRYKTWLQYLISTVTGIFLIRVLKGIGELDLHTPTLPSYRPLFFILVYLISTAVVTRWNLDIAGLLLQCVPTLLMVFTMWADILTLILILPTYELTKLYYLKEVKIGAERGWLWKTNFKRVNDIYEVDQAGEGVYLFPSKQKTSSITGTMLPLIKAILISCISNKWQFIYLLYLIFEVSYYLHKKIIDEIAGGTNFISRLVAALIEANWAFDNEEVRGLKKFFLLSSRVKELIIKHKVRNEVMVHWFGDEEVYGMPKLVGLVKAATLSKNKHCILCTVCEDREWRGETCPKCGRFGPPMTCGMTLADFEEKHYKRIFFREDQSEGPVREEYAGYLQYRARGQLFLRNLPVLATKVKMLLVGNLGTEVGDLEHLGWVLRGPAVCKKVTEHEKCTTSIMDKLTAFFGVMPRGTTPRAPVRFPTSLLKIRRGLETGWAYTHQGGISSVDHVTCGKDLLVCDTMGRTRVVCQSNNKMTDESEYGVKTDSGCPEGARCYVFNPEAVNISGTKGAMVHLQKTGGEFTCVTASGTPAFFDLKNLKGWSGLPIFEASSGRVVGRVKVGKNEDSKPTKLMSGIQTVSKSTTDLTEMVKKITTMNRGEFRQITLATGAGKTTELPRSVIEEIGRHKRVLVLIPLRAAAESVYQYMRQKHPSIAFNLRIGEMKEGDMATGITYASYGYFCQMPQPKLRAAMVEYSFIFLDEYHCATPEQLAIMGKIHRFSENLRVVAMTATPAGTVTTTGQKHPIEEFIAPEVMKGEDLGSEYLDIAGLKIPVEEMKSNMLVFVPTRNMAVETAKKLKAKGYNSGYYYSGEDPSNLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGLKRMAVTIGEQAQRRGRVGRVKPGRYYRSQETPVGSKDYHYDLLQAQRYGIEDGINITKSFREMNYDWSLYEEDSLMITQLEILNNLLISEELPMAVKNIMARTDHPEPIQLAYNSYETQVPVLFPKIKNGEVTDSYDNYTFLNARKLGDDVPPYVYATEDEDLAVELLGLDWPDPGNQGTVEAGRALKQVVGLSTAENALLVALFGYVGYQALSKRHIPVVTDIYSIEDHRLEDTTHLQYAPNAIKTEGKETELKELAQGDVQRCVEAMTNYAREGIQFMKSQALKVKETPTYKETMDTVTDYVKKFMEALTDSKEDIIKYGLWGTHTALYKSICARLGSETAFATLVVKWLAFGGESIADHVKQAATDLVVYYIINRPQFPGDTETQQEGRKFVASLLVSALVTYTYKSWNYNNLSKIVEPALATLPYAATALKLFAPTRLESVVILSTAIYKTYLSIRRGKSDGLLGTGVSAAMEIMSQNPVSVGIAVMLGVGAVAAHNAIEASEQKRTLLMKVFVKNFLDQAATDELVKESPEKIIMALFEAVQTVGNPLRLVYHLYGVFYKGWEAKELAQRTAGRNLFTLIMFEAVELLGVDSEGKIRQLSSNYILELLYKFRDSIKSSVREMAISWAPAPFSCDWTPTDDRIGLPQDNFLQVETKCPCGYKMKAVKNCAGELRLLEEEGSFLCRNKFGRGSRNYRVTKYYDDNLSEIKPVIRMEGHVELYYKGATIKLDFNNSKTILATDKWEVDHSTLVRVLKRHTGAGYHGAYLGEKPNHKHLIERDCATITKDKVCFLKMKRGCAFTYDLSLHNLTRLIELVHKNNLEDKEIPAVTVTTWLAYTFVNEDIGTIKPAFGEKVTPEMQEEITLQPAVVVDTTDVTVTVVGEAPTMTTGETPTAFTSSGSDPKGQQVLKLGVGEGQYPGTNPQRASLHEAIQGADERPSVLILGSDKATSNRVKTAKNVKVYRGRDPLEVRDMMRRGKILVIALSRVDNALLKFVDYKGTFLTRETLEALSLGRPKKKNITKAEAQWLLCLEDQMEELPDWFAAGEPIFLEANIKHDRYHLVGDIATIKEKAKQLGATDSTKISKEVGAKVYSMKLSNWVMQEENKQGNLTPLFEELLQQCPPGGQNKTAHMVSAYQLAQGNWMPTSCHVFMGTISARRTKTHPYEAYVKLRELVEEHKMKTLCPGSSLGKHNEWIIGKIKYQGNLRTKHMLNPGKVAEQLCREGHRRNVYNKTIGSVMTATGIRLEKLPVVRAQTDTTNFHQAIRDKIDKEENLQTPGLHKKLMEVFNALKRPELESSYDAVEWEELERGINRKGAAGFFERKNIGEILDSEKNKVEEIIDNLKKGRNIKYYETAIPKNEKRDVNDDWTSGDFVDEKKPRVIQYPEAKTRLAITKVMYKWVKQKPVVIPGYEGKTPLFQIFDKVKKEWDQFQNPVAVSFDTKAWDTQVTTKDLELIKDIQKYYFKKKWHKFIDTLTMHMSEVPVISADGEVYIRKGQRGSGQPDTSAGNSMLNVLTMVYAFCEATGVPYKSFDRVAKIHVCGDDGFLITERALGEKFASKGVQILYEAGKPQKITEGDKMKVAYQFDDIEFCSHTPIQVRWSDNTSSYMPGRNTTTILAKMATRLDSSGERGTIAYEKAVAFSFLLMYSWNPLIRRICLLVLSTELQVKPGKSTTYYYEGDPISAYKEVIGHNLFDLKRTSFEKLAKLNLSMSVLGAWTRHTSKRLLQDCVNMGVKEGNWLVNADRLVSSKTGNRYIPGEGHTLQGRHYEELVLARKQINNFQGTDRYNLGPIVNMVLRRLRVMMMTLIGRGV irf3_pig Interferon regulatory factor 3 IRF3 protein protein pig Sus scrofa (Pig) Pig MGTQKPRILPWLISQLNQGQLEGVAWLDEGHTRFRIPWKHGLRQDAQQEDFGIFQAWAEASGAYTPGKDKPDLPTWKRNFRSALNRKEALRLAEDHSKDPHDPHKIYEFVTSGVGDFPEPDTSLDLSGRYSTSDTHEDSLDKLLSGMDLASDAGPQSLTLALEQPPQLSLSPSVDAPASCPNLGVRENPLKQLLANDDEWEFQVTVFYRGCQVFQQTVCSPGGLRLVGSEAEDGTLAGQPVRLPDPAASLTDRGVADYVRRVLSCLGGGLALWRAGQWLWAQRLGHCHVYWAMGEELIPDSGHKPDGEVPKDREGGVFDLGPFIEDLIAFIEGSRRSPRYTLWFCMGQSWPQDEPWVKRLVMVKVVPMCLRALVDMARDGGASSLENTVDLHISNSHPLSLTSDQYKACLRDLVEDMDF 8B731861BE002284 npro-irf3-7 1 5 unspecified role unspecified role neutral component neutral component 6 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction 1B, 2A irf3-q68871_9flav-1 3 5 unspecified role unspecified role neutral component neutral component 6 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction 1C, 2B irf3-q68871_9flav-2 2 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component ecoli Escherichia coli (strain K12) direct interaction direct interaction 1D irf3-q68871_9flav-3 1 4 unspecified role unspecified role neutral component neutral component F1RK46:p.Gln2060_Pro2061insMetSer mutation mutation certain certain sequence position certain certain certain sequence position certain QP QMSP Mon Feb 27 13:47:51 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_pro2065met' Fri Dec 08 14:20:00 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065met_ser_pro' Wed May 02 18:09:27 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061met_ser_pro' Tue Jun 30 16:33:50 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln2060_Pro2061insMetSer' region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Wed May 02 19:02:50 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 19:56:07 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) physical association physical association 3A crebbp-irf3-1 1 4 unspecified role unspecified role neutral component neutral component F1RK46:p.Gln2060_Pro2061insMetSer mutation mutation certain certain sequence position certain certain certain sequence position certain QP QMSP Mon Feb 27 13:56:56 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_pro2065ser' Fri Dec 08 14:15:57 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065met_ser_pro' Wed May 02 18:15:12 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061met_ser_pro' Tue Jun 30 17:48:36 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln2060_Pro2061insMetSer' region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Wed May 02 18:35:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 16:37:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) physical association physical association 3A crebbp-crebbp-1 1 4 unspecified role unspecified role neutral component neutral component region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain F1RK46:p.Gln2060_Pro2061insMetSer mutation mutation certain certain sequence position certain certain certain sequence position certain QP QMSP Mon Feb 27 13:52:35 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_pro2065met' Fri Dec 08 14:03:57 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065met_ser_pro' Wed May 02 20:30:43 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061met_ser_pro' Tue Jun 30 20:10:05 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln2060_Pro2061insMetSer' ecoli Escherichia coli (strain K12) 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Wed May 02 16:50:30 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 17:20:16 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) physical association physical association 3A crebbp-irf3-5 1 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Wed May 02 17:53:31 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 17:41:21 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) 4 unspecified role unspecified role neutral component neutral component F1RK46:p.Gln2060_Pro2061insMetSer mutation mutation certain certain sequence position certain certain certain sequence position certain QP QMSP Mon Feb 27 13:40:48 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_pro2065met' Fri Dec 08 14:43:20 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065met_ser_pro' Wed May 02 16:48:01 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061met_ser_pro' Tue Jun 30 16:39:08 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln2060_Pro2061insMetSer' region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association 3A crebbp-irf3-6 3 4 unspecified role unspecified role neutral component neutral component region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain F1RK46:p.Pro2061delinsSerMet mutation mutation certain certain sequence position certain certain certain sequence position certain P SM Fri Dec 08 13:57:49 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_met' Wed May 02 18:41:17 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061ser_met' Tue Jun 30 19:18:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro2061delinsSerMet' ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser384Glu;Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Mon Feb 27 14:00:44 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'Ser384glu_ser394glu_ser396glu_ser400glu_thr402glu_ser403glu' Wed May 02 17:42:04 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser384glu,ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 19:36:28 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser384Glu;Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) physical association physical association 3B crebbp-irf3-7 3 4 unspecified role unspecified role neutral component neutral component region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain F1RK46:p.Pro2061delinsSerMet mutation mutation certain certain sequence position certain certain certain sequence position certain P SM Fri Dec 08 14:09:23 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_met' Wed May 02 17:47:18 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061ser_met' Tue Jun 30 18:18:06 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Pro2061delinsSerMet' ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component Q764M6:p.[Ser384Glu;Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu] mutation mutation certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain S E certain certain sequence position certain certain certain sequence position certain T E certain certain sequence position certain certain certain sequence position certain S E Mon Feb 27 13:58:28 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'ser384glu_ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Wed May 02 14:27:02 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'ser384glu,ser394glu,ser396glu,ser400glu,thr402glu,ser403glu' Tue Jun 30 20:04:55 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.[Ser384Glu;Ser394Glu;Ser396Glu;Ser400Glu;Thr402Glu;Ser403Glu]' ecoli Escherichia coli (strain K12) physical association physical association 3B crebbp-irf3-8 3 4 unspecified role unspecified role neutral component neutral component region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain pro2065ser_pro2065met multisulfide crosslinked residues multisulfide crosslinked residues certain certain sequence position certain certain certain sequence position certain P S certain certain sequence position certain certain certain sequence position certain P M ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association 4B crebbp-irf3-9 1 4 unspecified role unspecified role neutral component neutral component F1RK46:p.Gln2060_Pro2061insMetSer mutation mutation certain certain sequence position certain certain certain sequence position certain QP QMSP Mon Feb 27 13:44:44 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065ser_pro2065met' Fri Dec 08 14:27:46 GMT 2017 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2065met_ser_pro' Wed May 02 16:04:49 BST 2018 This feature has been corrected as a result of our quality control procedures. The original label was 'pro2061met_ser_pro' Tue Jun 30 18:32:27 BST 2020 This feature has been corrected as a result of our quality control procedures. The original label was 'p.Gln2060_Pro2061insMetSer' region binding region binding-associated region binding region certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) 5 unspecified role unspecified role neutral component neutral component Npro region binding region binding-associated region binding region range range range range 6 unspecified role unspecified role neutral component neutral component region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) physical association physical association 4A