IntAct European Bioinformatics Institute IntAct intact http://www.ebi.ac.uk/ http://www.ebi.ac.uk/intact/query/${ac} EBI-[0-9]+|IA:[0-9]+ INTerAction database (IntAct) provides an open source database and toolkit for the storage, presentation and analysis of molecular interactions. http://www.ebi.ac.uk/intact European Bioinformatics Institute; Wellcome Trust Genome Campus; Hinxton, Cambridge; CB10 1SD; United Kingdom http://www.ebi.ac.uk/intact/ The Hepatitis E virus intraviral interactome. The Hepatitis E virus intraviral interactome. Scientific reports 2014 imex curation Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG, Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG., Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG. Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar 21-10-2015: Contacted by IntAct-Help. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast 2 hybrid two hybrid 2H 2h Gal4 transcription regeneration two-hybrid yeast two hybrid 2-hybrid classical two hybrid classical two hybrid 2H two-hybrid 2-hybrid Gal4 transcription regeneration 2h yeast two hybrid Y2H Y-2H 2 hybrid predetermined predetermined participant predetermined Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar Accepted 2015-SEP-23 AT 11:04 BST AT 11:04 BST by ORCHARD 2015 imex curation The Hepatitis E virus intraviral interactome. The Hepatitis E virus intraviral interactome. Scientific reports 2014 imex curation Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG, Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG., Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG. Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar 21-10-2015: Contacted by IntAct-Help. Only protein-protein interactions in vitro In vitro mst microscale thermophoresis mst predetermined predetermined participant predetermined Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG Virus - Publications including interactions involving viral proteins EC50 parameter values registered in this entry refer to figure 4 and are consigned in the body text of the manuscript. These values slightly vary from the ones given in figure 5. 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar Accepted 2015-SEP-23 AT 11:04 BST AT 11:04 BST by ORCHARD 2015 imex curation The Hepatitis E virus intraviral interactome. The Hepatitis E virus intraviral interactome. Scientific reports 2014 imex curation Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG, Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG., Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG. Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar 21-10-2015: Contacted by IntAct-Help. Only protein-protein interactions human-293t Homo sapiens 293 cells transformed with SV40 large T antigen 293t 293 cells expressing SV40 large T antigen. The original designation of this cell line was 293tsA1609neo. It is not in Cabri,ATCC or HyperCLDB. lumier luminescence based mammalian interactome mapping lumier predetermined predetermined participant predetermined Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. A variant of LUMIER called LuMPIS (see PMID:19834906) was used. This methods uses an MBP tag to pull down baits and their associated preys, which are detected using luminescence emited by a tandem eGFP-luciferase tag. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar Accepted 2015-SEP-23 AT 11:04 BST AT 11:04 BST by ORCHARD 2015 imex curation The Hepatitis E virus intraviral interactome. The Hepatitis E virus intraviral interactome. Scientific reports 2014 imex curation Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG, Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG., Osterman A., Stellberger T., Gebhardt A., Kurz M., Friedel CC., Uetz P., Nitschko H., Baiker A., Vizoso-Pinto MG. Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar 21-10-2015: Contacted by IntAct-Help. Only protein-protein interactions yeasx Saccharomyces cerevisiae (Baker's yeast) Baker's yeast validated two hybrid validated two hybrid predetermined predetermined participant predetermined Osterman A,Stellberger T, Gebhardt A, Kurz M, Friedel CC, Uetz P, Nitschko H, Baiker A, Vizoso-Pinto MG Virus - Publications including interactions involving viral proteins 05-02-2015: Submitted by T Stellberger, Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Karlsruhe, Germany Files for this submission can be found in /pro6/intact/local/data/curation-material/2015/osterman-2015. Additional details on the HEV genome library (nucleotide sequence L08816) obtained from the authors. Only those interactions with "high" confidence scoring were registered in the validated 2 hybrid experiment, following the definition of the method. guadalupevizoso@yahoo.com, guadalupevizoso@conicet.gov.ar Accepted 2015-SEP-23 AT 11:04 BST AT 11:04 BST by ORCHARD 2015 imex curation capsd_hevhy Secreted protein ORF2 Protein ORF2 ORF2 protein protein isolate Human/India/Hyderabad Hepatitis E virus genotype 1 HEV-1 MGPRPILLLFLMFLPMLLAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQPFAIPYIHPTNPFAPNVTAAAGAGPRVRQPVRPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPNAVGGYAISISFWPQTTPTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFMKDLYFTSTNGVGEIGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRPVVSANGEPTVKLYTSVENAQQDKGIAIPNDIDLGESRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTIQQYSKIFFVLPLRGKLSFWEAGTTRPGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAGPVSISAVAVLGPHSALALLEDTLDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRLKMKVGKTREL 948556F804382EB3 orf3_hevhy Protein ORF3 ORF3 protein protein isolate Human/India/Hyderabad Hepatitis E virus genotype 1 HEV-1 MGSRPWALGLFCCCSSCFCLCCSRHRPVSRLAAVVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPRMSPLRPGLDLVFANPSDHSAPLGATRPSAPPLPHVVDLPQLGPRR 94DE3D4161FAD67D poln_hevhy Non-structural polyprotein pORF1 ORF1 protein protein isolate Human/India/Hyderabad Hepatitis E virus genotype 1 HEV-1 MEAHQFLKAPGITTAVEQAALATANSALANAVVVRPFLSHQQIEILINLMQPRQLVFRPEVFWNQPIQRVIHNELELYCRARSGRCLEIGAHPRSINDNPNVVHRCFLRPVGRDVQRWYTAPTRGPAANCRRSALRGLPAADRTYCFDGFSGCSCPAETGIALYSLHDMSPSDVAEAMFRHGMTRLYAALHLPPEVLLPPGTYRTASYLLIHDGRRVVVTYEGDTSAGYNHDVSNLRSWIRTTKVTGDHPLVIERVRAIGCHFVLLLTAAPEPSPMPYVPYPRSTEVYVRSIFGPGGTPSLFPTSCSTKSTFHAVPAHIWDRLMLFGATLDDQAFCCSRLMTYLRGISYKVTVGTLVANEGRNASEDALTAVITAAYLTICHQRYLRTQAISKGIRRLEREHDQKFITRLYSWLFEKSGRDYIPGRQLEFYAQCRRWLSAGFHLDPRVLVFDESAPCHCRTVIRKALSKFCCFMKWLGQECTCFLQPAEGVVGDQGHDNESYEGSDVDPAESAISDISGSYVVPGTALQPLYQALDLPDEIVARACRLTATVKVSQVDGRIDCETLLGNKTFRTSFVDGAVLETNGPERHNLSFDASQSTMAAGPFSLTYAASAAGLEVRYVGAGLDHRAIFAPGVSPRSNPGEVTAFCSALYRFNREAQRHSLTGNLWFHPEGLIGLFAPFSPGHVWESAKPFCGESTLYTRTWSEVDAVSSPTRPDLGFMSEPPIPSRAATPTLAAPLPPLAPDPSPPSSAPALDEPASAATSGVPAITHQTARHRRLLFTYPDGSKVFAGSLFESTCTWLVNASNVDHCPGGGLCHAFYQRYPASFDAACFVMRDGAAAYTLTPRPIIHRVAPDYRLEHNPKRLEAAYRETCSRLGTAAYPLLGTGIYQVPIGPSFDAWERNHRPGDELYLPELAARWFEANRPTRPTLTITEDAARTANLAIELDSATDVGRACAGCRVTPGVVQYQFTAGVPGSGKSRSITRADVDVVVVPTRELRNAWRRRGFAAFTPHTAARVTDGRRVVIDEAPSLPPHLLLLHMQRAATVHLLGDPNQIPAIDFEHPGLVPAIRPDLAPTSWWHVTHRCPADVCELIRGAYPMIQTTSRVLRSLFWGEPAVGQKLVFTQAAKPANPGSVTVHDSQGATYTYTTIIATADARGLIQSSRAHAIVALTRHTEKWVIIDAPGLLREVGISDAIVNNFFLAGGEIGHQRPSVIPRGNPDANVDTLAAFPPSCQISAFHQLAEELGHRPAPVAAVLPPCPELEQGLLYLPQELTTCDSVVTFELTDIVHCRMAAPSQRKAVVSTLVGRYGRRTKLYNASHSDVRDSLARFIPAIGPVQVTTCELYELVEAMVEKGQDGSAVLELDLCNRDVSRITFFQKDCNKFTTGETIAHGKVGQGISAWSKTFCALFGPWFRAIEKAILALLPQGVFYGDAFDDTVFSAAVAAAKASMVFENDFSEFDSTQNNFSLGLECAIMEECGMPQGLIRLYHLIRSAWILQAPKESLLGFWKKHSGEPGTLLWNTVWNMAVITHCYDFRDLQVAAFKGDDSIVLCSEYRQSPGAAVLIAGCGLKLKVDFRPMRLYAGVVVAPGLGALPDVVRFAGRLTEKNWGPGPERADELRIAVSDFLRKLTNVAQMCVDVVSRVYGVSPGLVHNLIGMLQAVADGKAHFTESVKPVLDLTNSILCRVE FB37B87BF6BBB501 orf3_hevhy-poln_hevhy-1 2 Plp 7 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range plp region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) O3 6 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecoli Escherichia coli (strain K12) direct interaction direct interaction 4a, 5a, 5b The interaction was tested at different temperatures, showing inverse dependency: 30°C (0.3nM)>35°C (2.8nM)>37°C (16nM)>41°C (19nM). Analogously, different pHs were tested. The strongest binding was detected at a pH of 7 (EC50: 0.3 nM). Unless otherwise stated, temp=30C, pH=7. orf3_hevhy-poln_hevhy-2 2 Pvx 7 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range pvx region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) O3 6 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecoli Escherichia coli (strain K12) direct interaction direct interaction 4b Temp=30C, pH=7 orf3_hevhy-poln_hevhy-3 2 X 7 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range x region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) O3 6 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecoli Escherichia coli (strain K12) direct interaction direct interaction 4c Temp=30C, pH=7 orf3_hevhy-poln_hevhy-4 2 Met 7 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Met region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) O3 6 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecoli Escherichia coli (strain K12) direct interaction direct interaction 4d Temp=30C, pH=7 orf3_hevhy-poln_hevhy-5 2 Hel 7 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range Hel region sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain ecoli Escherichia coli (strain K12) O3 6 unspecified role unspecified role neutral component neutral component purified purified n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range ecoli Escherichia coli (strain K12) direct interaction direct interaction 4e Temp=30C, pH=7 orf3-orf3-2 1 O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 34 high orf3-orf3-3 1 O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 34 high orf3-orf3-4 1 O3 6 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 34 high orf3-orf3-5 1 O3 6 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 34 high poln-orf3-21 1 Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 2 high poln-orf3-1 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 23 high poln-orf3-2 1 Met 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 2 high poln-orf3-3 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 23 high poln-orf3-4 1 Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 2 high poln-orf3-5 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 14 high poln-orf3-6 1 O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 9 high poln-orf3-7 1 X 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 23 high poln-orf3-8 1 Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 29 high poln-orf3-9 1 Met 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 2 high poln-orf3-10 1 O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 14 high poln-orf3-11 1 Plp 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 9 high poln-orf3-12 1 O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 23 high poln-orf3-13 1 Hel 7 unspecified role unspecified role bait bait hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 25 medium poln-orf3-14 1 O3 6 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 29 high capsd-capsd-24 1 O2_S 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_FLd 5 unspecified role unspecified role bait bait o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 4 capsd-capsd-1 1 O2_P1P2 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_FLd 5 unspecified role unspecified role bait bait o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 2 capsd-capsd-2 1 O2_S 5 unspecified role unspecified role prey prey o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_P1 5 unspecified role unspecified role bait bait o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 9 capsd-capsd-3 1 O2_P1P2 5 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_P1P2 5 unspecified role unspecified role prey prey o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 13 capsd-capsd-4 1 O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_S 5 unspecified role unspecified role prey prey o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 19 capsd-capsd-5 1 O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_P2 5 unspecified role unspecified role prey prey o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 18 capsd-capsd-6 1 O2_S 5 unspecified role unspecified role prey prey o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_SP1 5 unspecified role unspecified role bait bait o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 22 capsd-capsd-7 1 O2_SP1 5 unspecified role unspecified role prey prey o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_FLd 5 unspecified role unspecified role bait bait o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 5 capsd-capsd-8 1 O2_SP1 5 unspecified role unspecified role bait bait o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_P1 5 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 20 capsd-capsd-9 1 O2_FLd 5 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_P2 5 unspecified role unspecified role prey prey o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association Table 3, fig. 2b Table 3 - 3 capsd-capsd-10 1 O2_P1 5 unspecified role unspecified role bait bait o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_S 5 unspecified role unspecified role prey prey o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association Table 3, fig. 2b Table 3 - 9 capsd-capsd-11 1 O2_P1 5 unspecified role unspecified role prey prey o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P1P2 5 unspecified role unspecified role bait bait o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 12 capsd-capsd-12 1 O2_P1 5 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_P1 5 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 7 capsd-capsd-13 1 O2_S 5 unspecified role unspecified role prey prey o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 19 capsd-capsd-14 1 O2_P2 5 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 18 capsd-capsd-15 1 O2_S 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_SP1 5 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 22 capsd-capsd-16 1 O2_S 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_s domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_FLd 5 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 4 capsd-capsd-17 1 O2_SP1 5 unspecified role unspecified role bait bait o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P1 5 unspecified role unspecified role prey prey o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 20 capsd-capsd-18 1 O2_P1 5 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_SP1 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_sp1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 10 capsd-capsd-19 1 O2_P1P2 5 unspecified role unspecified role bait bait o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P1 5 unspecified role unspecified role prey prey o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association Table 3, fig. 2b Table 3 - 12 capsd-capsd-20 1 O2_P1 5 unspecified role unspecified role bait bait o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P1 5 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true o2_p1 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 7 capsd-capsd-21 1 O2_P1P2 5 unspecified role unspecified role prey prey o2_p1p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association Table 3, fig. 2b Table 3 - 17 capsd-capsd-22 1 O2_P2 5 unspecified role unspecified role bait bait o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2_P2 5 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_p2 domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, fig. 2b Table 3 - 18 orf3-poln-10 1 Pvx 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 33 high orf3-poln-1 1 O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true X 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 32 high orf3-poln-2 1 O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 31 high orf3-poln-3 1 O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 33 high orf3-poln-4 1 O3 6 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 32 high orf3-poln-5 1 O3 6 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 32 high orf3-poln-6 1 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 33 high orf3-poln-7 1 O3 6 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 32 high capsd-poln-2 1 O2 5 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 35 medium poln-poln-72 1 Met 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 1 high poln-poln-1 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 11 high poln-poln-2 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 6 high poln-poln-3 1 Met 7 unspecified role unspecified role prey prey met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 18 high poln-poln-4 1 X 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 20 high poln-poln-5 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 3 medium poln-poln-6 1 Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 4 high poln-poln-7 1 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 1 high poln-poln-8 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 10 high poln-poln-9 1 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 11 high poln-poln-10 1 Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 6 high poln-poln-11 1 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 8 high poln-poln-12 1 V 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true v protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 15 medium poln-poln-13 1 V 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true v protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true V 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true v protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 17 medium poln-poln-14 1 X 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Met 7 unspecified role unspecified role prey prey met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 18 high poln-poln-15 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 19 medium poln-poln-16 1 Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 21 high poln-poln-17 1 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 20 high poln-poln-18 1 Hel 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 22 high poln-poln-19 1 Rdrp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Rdrp 7 unspecified role unspecified role bait bait c-terminal dna binding domain dna binding domain tag dna binding domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 30 medium poln-poln-20 1 Met 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 1 high poln-poln-21 1 Met 7 unspecified role unspecified role prey prey met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 12 high poln-poln-22 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 10 high poln-poln-23 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 11 high poln-poln-24 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Plp 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 6 high poln-poln-25 1 Plp 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 8 high poln-poln-26 1 Pvx 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 13 high poln-poln-27 1 Plp 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 7 medium poln-poln-28 1 V 7 unspecified role unspecified role bait bait v protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true V 7 unspecified role unspecified role prey prey v protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 17 medium poln-poln-29 1 X 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Met 7 unspecified role unspecified role prey prey met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 18 high poln-poln-30 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 21 high poln-poln-31 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 20 high poln-poln-32 1 X 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Hel 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 24 high poln-poln-33 1 Pvx 7 unspecified role unspecified role prey prey c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 28 high poln-poln-34 1 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 27 medium poln-poln-35 1 Rdrp 7 unspecified role unspecified role prey prey rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true c-terminal activation domain activation domain tag activation domain c-term range C-terminal range c-term range c-term range C-terminal range c-term range true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 30 medium poln-poln-36 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 3 medium poln-poln-37 1 Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Met 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 4 high poln-poln-38 1 Met 7 unspecified role unspecified role bait bait met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 1 high poln-poln-39 1 Y 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true y protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 5 medium poln-poln-40 1 Pvx 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Met 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 12 high poln-poln-41 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 10 high poln-poln-42 1 Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 11 high poln-poln-43 1 Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 6 high poln-poln-44 1 Plp 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 8 high poln-poln-45 1 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 13 high poln-poln-46 1 X 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 7 medium poln-poln-47 1 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Rdrp 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 16 high poln-poln-48 1 Met 7 unspecified role unspecified role prey prey met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 18 high poln-poln-49 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 19 medium poln-poln-50 1 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 21 high poln-poln-51 1 X 7 unspecified role unspecified role bait bait n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 20 high poln-poln-52 1 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Hel 7 unspecified role unspecified role prey prey hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 22 high poln-poln-53 1 Hel 7 unspecified role unspecified role bait bait hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 24 high poln-poln-54 1 Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 26 medium poln-poln-55 1 Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role prey prey n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 28 high poln-poln-56 1 Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal dna binding domain dna binding domain tag dna binding domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal activation domain activation domain tag activation domain n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 27 medium orf3-orf3-1 3 O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 34 high capsd-orf3 3 O2 5 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association Figs. 3 and 2b poln-orf3-15 3 Met 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 2 high poln-orf3-16 3 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 14 high poln-orf3-17 3 O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 9 high poln-orf3-18 3 X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 23 high poln-orf3-19 3 O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Hel 7 unspecified role unspecified role bait bait hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 25 medium poln-orf3-20 3 O3 6 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Rdrp 7 unspecified role unspecified role bait bait rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 29 high capsd-capsd-23 3 O2_FLd 5 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O2_FLd 5 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true o2_fld domain sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 3, figs. 3 and 2b orf3-poln-8 3 O3 6 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 31 high orf3-poln-9 3 Pvx 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 33 high capsd-poln-1 3 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true O2 5 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 35 medium poln-poln-57 3 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Met 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 4 high poln-poln-58 3 Met 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 1 high poln-poln-59 3 Y 7 unspecified role unspecified role bait bait y protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score medium Table 2, figs. 3 and 2b Table 2 - 5 medium poln-poln-60 3 Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Met 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 12 high poln-poln-61 3 Plp 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 10 high poln-poln-62 3 Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 11 high poln-poln-63 3 Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Plp 7 unspecified role unspecified role prey prey plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 6 high poln-poln-64 3 Plp 7 unspecified role unspecified role bait bait plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 8 high poln-poln-65 3 X 7 unspecified role unspecified role prey prey x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true Pvx 7 unspecified role unspecified role bait bait pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 13 high poln-poln-66 3 Pvx 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Rdrp 7 unspecified role unspecified role prey prey rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 16 high poln-poln-67 3 X 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 21 high poln-poln-68 3 X 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role bait bait x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 20 high poln-poln-69 3 Hel 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 22 high poln-poln-70 3 X 7 unspecified role unspecified role prey prey n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Hel 7 unspecified role unspecified role bait bait hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 24 high poln-poln-71 3 Rdrp 7 unspecified role unspecified role bait bait n-terminal mbp tag maltose binding protein tag maltose binding protein tag maltose binding protein tag mbp tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role prey prey pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true n-terminal egfp-luciferase tandem tag tandem tag tandem tag n-term range n-terminal range n-term range n-term range n-terminal range n-term range true physical association physical association author score author-based confidence author score high Table 2, figs. 3 and 2b Table 2 - 28 high orf3-orf3-6 4 O3 6 unspecified role unspecified role neutral component neutral component O3 6 unspecified role unspecified role neutral component neutral component physical association physical association Table 2, figs. 3 and 2b Table 2 - 34 orf3-poln-11 4 O3 6 unspecified role unspecified role neutral component neutral component Met 7 unspecified role unspecified role neutral component neutral component met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 2 orf3-poln-12 4 X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true O3 6 unspecified role unspecified role neutral component neutral component physical association physical association Table 2, figs. 3 and 2b Table 2 - 23,32 orf3-poln-13 4 O3 6 unspecified role unspecified role neutral component neutral component Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 14,33 orf3-poln-14 4 O3 6 unspecified role unspecified role neutral component neutral component Rdrp 7 unspecified role unspecified role neutral component neutral component rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 29 orf3-poln-15 4 O3 6 unspecified role unspecified role neutral component neutral component Plp 7 unspecified role unspecified role neutral component neutral component plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 31,9 poln-poln-73 4 Met 7 unspecified role unspecified role neutral component neutral component met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 1,18 poln-poln-74 4 Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 11 poln-poln-75 4 Plp 7 unspecified role unspecified role neutral component neutral component plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Plp 7 unspecified role unspecified role neutral component neutral component plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 6 poln-poln-76 4 X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 20 poln-poln-77 4 Met 7 unspecified role unspecified role neutral component neutral component met protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 4,12 poln-poln-78 4 Plp 7 unspecified role unspecified role neutral component neutral component plp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 8,10 poln-poln-79 4 Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 13,21 poln-poln-80 4 X 7 unspecified role unspecified role neutral component neutral component x protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Hel 7 unspecified role unspecified role neutral component neutral component hel protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 22, 24 poln-poln-81 4 Rdrp 7 unspecified role unspecified role neutral component neutral component rdrp protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true Pvx 7 unspecified role unspecified role neutral component neutral component pvx protein sufficient to bind sufficient binding region sufficient to bind certain certain sequence position certain certain certain sequence position certain true physical association physical association Table 2, figs. 3 and 2b Table 2 - 16,28